methacycline has been researched along with inositol 1,4,5-trisphosphate in 78 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (26.92) | 18.7374 |
| 1990's | 39 (50.00) | 18.2507 |
| 2000's | 10 (12.82) | 29.6817 |
| 2010's | 8 (10.26) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Müller, S; Nigam, S; Walzog, B | 1 |
| Küntzel, H; Schomerus, C | 1 |
| Andersson, T; Fällman, M; Nilsson, E; Palmblad, J; Rosendahl, K | 1 |
| Cerpovicz, PF; Ochs, RS | 1 |
| Kaiya, H | 1 |
| Nakashima, S; Nozawa, Y; Okano, Y; Suganuma, A | 1 |
| Rosales, OR; Sumpio, BE | 1 |
| Abdel-Latif, AA; Zhang, YW | 1 |
| Firsov, DL; Parnova, RG | 1 |
| Cook, SJ; Palmer, S; Plevin, R; Wakelam, MJ | 1 |
| Izawa, T; Komabayashi, T; Noguchi, M; Suda, K; Tsuboi, M; Yakata, A | 1 |
| Elmore, M; Kellie, S; Murphy, CT; Westwick, J | 1 |
| Baker, RC; French, TA; Masserano, JM; Weiner, EA | 1 |
| Kato, M; Takenawa, T; Yamakawa, A | 1 |
| Sit, KH; Wong, KP | 1 |
| Capponi, AM; Johnson, EI; Lang, U; Vallotton, MB | 1 |
| Sandmann, J; Wurtman, RJ | 1 |
| King, WG; Kucera, GL; Rittenhouse, SE; Sorisky, A | 1 |
| Baukal, AJ; Bor, M; Catt, KJ; Ely, JA; Hunyady, L | 1 |
| Brock, TA; Danthuluri, NR | 1 |
| Bonser, RW; Garland, LG; Randall, RW; Spacey, GD; Tateson, JE; Thompson, NT | 1 |
| Pfeilschifter, J | 1 |
| Exton, JH | 2 |
| Holub, BJ | 1 |
| Abdel-Latif, AA; Akhtar, RA; Yousufzai, SY | 1 |
| Murer, H; Pfeilschifter, J; Quamme, G | 1 |
| Araki, S; Fukuzaki, H; Kariya, K; Kawahara, Y; Sunako, M; Takai, Y | 1 |
| Drozdova, EI; Kotliar, BI; Pivovarov, AS | 1 |
| Fukami, K; Takenawa, T | 1 |
| Abdel-Latif, AA | 1 |
| Gershengorn, MC | 1 |
| Cooper, RH; Joseph, SK; Thomas, AP; Williamson, JR | 1 |
| Aghajanian, GK; Freedman, JE | 1 |
| Albrecht, T; Bandi, Z; Boldogh, I; Valyi-Nagy, T | 1 |
| Berridge, MJ | 4 |
| Cantley, L; Chahwala, SB; Fleischman, LF | 1 |
| Knight, DE; Niggli, V; Scrutton, MC | 1 |
| Bajjalieh, SM; Kowalchyk, JA; Lucas, DO; Martin, TF | 1 |
| Bollag, WE; Rasmussen, H; Takuwa, N; Takuwa, Y | 1 |
| Biden, TJ; Bruzzone, R; Farese, RV; Trimble, ER | 1 |
| Bhattacharya, RK; Choudhury, S; Krishna, M | 1 |
| Endo, K; Mitsui, H; Takei, M | 1 |
| Advenier, C; Grandordy, BM; Lacroix, H; Mavoungou, E; Naline, E; Roux, F; Tordet, C | 1 |
| Agui, T; Cai, Y; Matsumoto, K; Sakai, T; Xin, X | 1 |
| Banfić, H; Lasić, Z; Somogyi, L; Vukicević, S | 1 |
| Nahorski, SR; Tobin, AB; Wojcikiewicz, RJ | 1 |
| Nahorski, SR; Wojcikiewicz, RJ | 1 |
| Allan, CJ; Exton, JH | 1 |
| Ochi, S; Sakurai, J; Tanaka, H | 1 |
| Banfić, H; Jaksić, O; Knotek, M; Selmani, R; Skorić, B | 1 |
| Kirchgessner, M; Moser, C; Roth, HP | 1 |
| Helliwell, RM; Large, WA | 1 |
| Espinoza, R; Smart, T; Stith, BJ; Woronoff, K | 1 |
| del Río, E; Downes, CP; Nicholls, DG; Shinomura, T; van der Kaay, J | 1 |
| Assmann, G; Kehrel, B; Nofer, JR; Seedorf, U; Tepel, M; Walter, M; Wierwille, S | 1 |
| Boland, R; Picotto, G; Vazquez, G | 1 |
| Ishii, Y; Kimura, T; Mochizuki, M; Morishima, Y; Nomura, A; Sakamoto, T; Sekizawa, K; Uchida, Y | 1 |
| Kong, XT; Wu, ZG; Yan, JC; Zhan, LZ; Zong, RQ | 1 |
| Bolton, TB; Gordienko, DV; Tsvilovskyy, VV; Tsytsyura, YD; Zholos, AV | 1 |
| Ikari, S; Matsuda, H; Ochi, S; Oda, M; Sakurai, J | 1 |
| Dent, MR; Dhalla, NS; Tappia, PS | 1 |
| Hisatsune, C; Kuroda, Y; Mikoshiba, K; Nakamura, K; Nakamura, T | 1 |
| Akagi, M; Fukuyama, Y; Mitsumoto, Y; Nakade, K; Oda, M; Sakurai, J; Zhai, H | 1 |
| Brown, Z; Cronshaw, DG; Kouroumalis, A; Parry, R; Ward, SG; Webb, A | 1 |
| Nurrish, SJ; Saiardi, A; Tokuoka, SM | 1 |
| Chen, G; Du, R; Liu, P; Wang, C; Yan, J | 1 |
| Aggarwal, P; Akbulut, S; Ambardekar, C; Basson, MA; Canciani, B; Collins, S; Hix, L; Kim, MK; Licht, JD; Lovatt, M; Mason, J; Phillips, M; Powell, J; Quatela, S; Reddi, AL; Vilimas, T | 1 |
| Fu, G; Huang, W; Peng, D; Wang, X; Wang, Y; Zhou, X | 1 |
| Iwata, T; Kikuyama, S; Nakada, T; Shioda, S; Toyoda, F; Yada, T | 1 |
| Wang, C; Wang, Z; Yan, J; Yuan, W | 1 |
| Albus, A; Bünemann, M; Greifenberg, L; Kronimus, Y; Leitner, MG; Lindner, M; Oliver, D; Wilke, BU | 1 |
| Stith, BJ | 1 |
| Bhatnagar, N; Pandey, A; Pandey, GK; Singh, A | 1 |
| Machaty, Z | 1 |
18 review(s) available for methacycline and inositol 1,4,5-trisphosphate
| Article | Year |
|---|---|
Second messenger imbalance hypothesis of schizophrenia.
Topics: Antipsychotic Agents; Blood Platelets; Calcium; Cyclic AMP; Diglycerides; Humans; Inositol 1,4,5-Trisphosphate; Models, Neurological; Nerve Tissue Proteins; Phosphatidylinositols; Phosphorylation; Protein Kinase C; Protein Processing, Post-Translational; Receptors, Dopamine; Schizophrenia; Second Messenger Systems; Synaptic Transmission | 1992 |
Mode of action of angiotensin II and vasopressin on their target cells.
Topics: Angiotensin II; Animals; Calcium; Diglycerides; Glomerular Mesangium; Humans; Hydrogen; Inositol 1,4,5-Trisphosphate; Muscle, Smooth, Vascular; Protein Kinase C; Receptors, Angiotensin; Signal Transduction; Sodium; Vasopressins; Zona Glomerulosa | 1990 |
The regulation of Ca2+ accumulation and phospholipid metabolism in human platelets.
Topics: Blood Platelets; Calcium; Cholesterol; Diglycerides; GTP-Binding Proteins; Humans; Inositol 1,4,5-Trisphosphate; Ion Channel Gating; Membrane Lipids; Phorbol Esters; Phospholipases A; Phospholipids; Protein Kinase C; Signal Transduction; Thrombin | 1990 |
Regulatory functions of protein kinase C in glomerular mesangial cells.
Topics: Diglycerides; Enzyme Activation; Glomerular Mesangium; Humans; Hydrolysis; Inositol 1,4,5-Trisphosphate; Phosphatidylcholines; Phosphatidylinositols; Phospholipases A; Prostaglandins; Protein Kinase C | 1990 |
Mechanisms involved in alpha-adrenergic phenomena.
Topics: Adenylyl Cyclases; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Calcium; Cyclic AMP; Diglycerides; Epinephrine; Glycerides; Guanine Nucleotides; Humans; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Ion Channels; Liver; Liver Glycogen; Muscle, Smooth; Norepinephrine; Phosphatidylinositols; Protein Kinase C; Protein Kinases; Receptors, Adrenergic, alpha; Sugar Phosphates | 1985 |
Metabolism and function of myo-inositol and inositol phospholipids.
Topics: Absorption; Animals; Arachidonic Acid; Arachidonic Acids; Biological Transport, Active; Carrier Proteins; Cell Membrane; Diabetes Mellitus; Diet; Digestion; Diglycerides; Female; Humans; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kidney Diseases; Liver; Lung; Male; Phosphatidic Acids; Phosphatidylinositols; Phospholipids; Pregnancy; Tissue Distribution; Triglycerides; Whipple Disease | 1986 |
[Second messengers in the regulation of nerve cell plasticity during learning].
Topics: Animals; Calcium; Calmodulin; Cyclic AMP; Cyclic GMP; Diglycerides; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Learning; Neuronal Plasticity; Neurons; Protein Kinase C; Second Messenger Systems | 1989 |
Calcium-mobilizing receptors, polyphosphoinositides, generation of second messengers and contraction in the mammalian iris smooth muscle: historical perspectives and current status.
Topics: Animals; Diglycerides; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Iris; Muscle Contraction; Muscle, Smooth; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Receptors, Neurotransmitter; Second Messenger Systems | 1989 |
Inositol trisphosphate and diacylglycerol as intracellular second messengers in liver.
Topics: Adrenergic alpha-Agonists; Angiotensin II; Animals; Calcium; Cell Communication; Cell Membrane; Cell Membrane Permeability; Diglycerides; Endoplasmic Reticulum; Glycerides; Humans; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Ion Channels; Liver; Mitochondria, Liver; Phenylephrine; Protein Kinase C; Protein Kinases; Receptors, Cell Surface; Stimulation, Chemical; Sugar Phosphates; Vasopressins | 1985 |
Permeabilized platelets and exocytosis.
Topics: Acetylglucosaminidase; Blood Platelets; Calcium; Cell Membrane Permeability; Cyclic AMP; Cyclic GMP; Cytosol; Diglycerides; Electricity; Exocytosis; Guanosine Triphosphate; Humans; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Microscopy, Electron; Serotonin | 1985 |
Ernst Klenk Lecture, November 1985. Intracellular signalling through inositol trisphosphate and diacylglycerol.
Topics: Adenosine Triphosphate; Animals; Body Fluids; Calcium; Cell Communication; Cell Membrane Permeability; Diglycerides; Glycerides; Hydrolysis; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Intracellular Fluid; Models, Biological; Muscle Contraction; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Sugar Phosphates | 1986 |
Cell signalling through phospholipid metabolism.
Topics: Animals; Cell Communication; Cell Differentiation; Cell Division; Cell Membrane; Cyclic AMP; Diglycerides; Humans; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Models, Biological; Nervous System; Oocytes; Phospholipids | 1986 |
Inositol trisphosphate and diacylglycerol as second messengers.
Topics: Acetylcholine; Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcium; Cell Division; Chemical Phenomena; Chemistry; Diglycerides; Drug Synergism; Enzyme Activation; Glycerides; Guanylate Cyclase; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Lithium; Models, Biological; Phosphatidylinositols; Protein Kinase C; Protein Kinases; Receptors, Cell Surface; Sugar Phosphates | 1984 |
Desensitization of cell signalling mediated by phosphoinositidase C.
Topics: Animals; Calcium; Cell Line; Cell Membrane; Diglycerides; Down-Regulation; Humans; Inositol 1,4,5-Trisphosphate; Membrane Proteins; Phosphoric Diester Hydrolases; Phosphorylation; Receptors, Cell Surface; Signal Transduction | 1993 |
Regulation of phosphoinositide phospholipases by hormones, neurotransmitters, and other agonists linked to G proteins.
Topics: Animals; Calcium; Diglycerides; Enzyme Activation; Growth Substances; GTP-Binding Proteins; Hormones; Inositol 1,4,5-Trisphosphate; Isoenzymes; Neurotransmitter Agents; Phosphatidylinositol Diacylglycerol-Lyase; Phosphoric Diester Hydrolases; Phosphotransferases (Alcohol Group Acceptor); Type C Phospholipases | 1996 |
Phospholipase C and D regulation of Src, calcium release and membrane fusion during Xenopus laevis development.
Topics: Animals; Calcium; Diglycerides; Fertilization; Inositol 1,4,5-Trisphosphate; Lipid Metabolism; Membrane Fusion; Phosphatidic Acids; Phospholipase D; src-Family Kinases; Type C Phospholipases; Xenopus laevis | 2015 |
Plant phospholipase C family: Regulation and functional role in lipid signaling.
Topics: Calcium; Diglycerides; Inositol 1,4,5-Trisphosphate; Lipid Metabolism; Plant Proteins; Plants; Protein Processing, Post-Translational; Signal Transduction; Type C Phospholipases | 2015 |
Signal transduction in mammalian oocytes during fertilization.
Topics: Animals; Calcium Signaling; Diglycerides; Female; Fertilization; Humans; Inositol 1,4,5-Trisphosphate; Male; Oocytes; Signal Transduction; Sperm-Ovum Interactions; Spermatozoa; Type C Phospholipases | 2016 |
60 other study(ies) available for methacycline and inositol 1,4,5-trisphosphate
| Article | Year |
|---|---|
Effect of staurosporine on fMet-Leu-Phe-stimulated human neutrophils: dissociated release of inositol 1,4,5-trisphosphate, diacylglycerol and intracellular calcium.
Topics: Alkaloids; Calcium; Diglycerides; Enzyme Activation; Humans; Inositol 1,4,5-Trisphosphate; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Phospholipase D; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate | 1992 |
CDC25-dependent induction of inositol 1,4,5-trisphosphate and diacylglycerol in Saccharomyces cerevisiae by nitrogen.
Topics: Cell Cycle Proteins; Diglycerides; Fungal Proteins; Inositol 1,4,5-Trisphosphate; Nitrogen; Phosphatidylinositol Diacylglycerol-Lyase; Phosphoinositide Phospholipase C; Phosphoric Diester Hydrolases; Radioligand Assay; ras-GRF1; Saccharomyces cerevisiae; Signal Transduction | 1992 |
Effects of ethanol on the chemotactic peptide-induced second messenger generation and superoxide production in polymorphonuclear leukocytes.
Topics: Calcium; Diglycerides; Ethanol; Humans; Inositol 1,4,5-Trisphosphate; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Propranolol; Superoxides | 1992 |
Effects of EGF on the mass of inositol 1,4,5-trisphosphate and SN(1,2)-diacylglycerol in freshly isolated rat hepatocytes: comparison with vasopressin.
Topics: Animals; Calcium; Chlorides; Diglycerides; Egtazic Acid; Enzyme Activation; Epidermal Growth Factor; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Kinetics; Lithium; Lithium Chloride; Liver; Protein Kinase C; Rats; Vasopressins | 1992 |
Mass contents of inositol 1,4,5-trisphosphate and 1,2-diacylglycerol in human platelets stimulated with a thromboxane analogue and thrombin.
Topics: Blood Platelets; Calcium; Diglycerides; Humans; Inositol 1,4,5-Trisphosphate; Manganese; Prostaglandin Endoperoxides, Synthetic; Thrombin; Thromboxanes | 1992 |
Changes in cyclic strain increase inositol trisphosphate and diacylglycerol in endothelial cells.
Topics: Animals; Cells, Cultured; Diglycerides; Endothelium, Vascular; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Periodicity; Stress, Mechanical | 1992 |
Species differences in the effects of endothelin-1 on myo-inositol trisphosphate accumulation, cyclic AMP formation and contraction of isolated iris sphincter of rabbit and other species.
Topics: Animals; Calcium Channel Blockers; Cyclic AMP; Diglycerides; Dose-Response Relationship, Drug; Endothelins; Humans; Inositol 1,4,5-Trisphosphate; Iris; Muscle Contraction; Phosphatidic Acids; Phospholipids; Pupil; Species Specificity | 1991 |
ADH-dependent phosphoinositide signalling system and prostaglandin E production in the frog urinary bladder.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Diglycerides; Inositol 1,4,5-Trisphosphate; Lipoprotein Lipase; Neomycin; Osmosis; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Prostaglandins E; Rana temporaria; Signal Transduction; Type C Phospholipases; Urinary Bladder; Vasopressins | 1991 |
Multiple sources of sn-1,2-diacylglycerol in platelet-derived-growth-factor-stimulated Swiss 3T3 fibroblasts. Evidence for activation of phosphoinositidase C and phosphatidylcholine-specific phospholipase D.
Topics: Cell Line; Choline; Diglycerides; Enzyme Activation; Fibroblasts; Glycerophospholipids; Inositol 1,4,5-Trisphosphate; Kinetics; Phosphatidic Acids; Phosphatidylcholines; Phosphatidylinositols; Phospholipase D; Phosphoric Diester Hydrolases; Platelet-Derived Growth Factor | 1991 |
Substance P-induced diacylglycerol formation in rat parotid acinar cells.
Topics: Alkaloids; Animals; Cells, Cultured; Choline; Diglycerides; Ethanolamine; Ethanolamines; Hydrolysis; Inositol 1,4,5-Trisphosphate; Kinetics; Male; Parotid Gland; Phosphatidylcholines; Phosphatidylethanolamines; Phosphorus Radioisotopes; Protein Kinase C; Rats; Rats, Inbred Strains; Staurosporine; Stimulation, Chemical; Substance P; Tritium | 1991 |
The relationship between cytosolic Ca2+, sn-1,2-diacylglycerol and inositol 1,4,5-trisphosphate elevation in platelet-activating-factor-stimulated rabbit platelets. Influence of protein kinase C on production of signal molecules.
Topics: Alkaloids; Animals; Blood Platelets; Calcium; Cytosol; Diglycerides; Dose-Response Relationship, Drug; Homeostasis; Inositol 1,4,5-Trisphosphate; Kinetics; Phosphorylation; Platelet Activating Factor; Platelet Activation; Protein Kinase C; Rabbits; Staurosporine; Thromboxane B2 | 1991 |
Differential effects of norepinephrine on phosphatidylinositol 4,5-bisphosphate stimulated hydrolysis in brains of mice genetically selected for differences in ethanol sensitivity.
Topics: Animals; Arousal; Brain; Diglycerides; Dose-Response Relationship, Drug; Ethanol; Inositol 1,4,5-Trisphosphate; Mice; Mice, Inbred Strains; Norepinephrine; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Second Messenger Systems; Selection, Genetic; Sleep Stages | 1990 |
Phosphatidylinositol kinase and cell transformation.
Topics: 1-Phosphatidylinositol 4-Kinase; Amino Acid Sequence; Animals; Cell Division; Cell Transformation, Neoplastic; Cell Transformation, Viral; Chick Embryo; Diglycerides; Fibroblasts; Inositol 1,4,5-Trisphosphate; Mitogens; Molecular Sequence Data; Oncogene Protein pp60(v-src); Oncogene Proteins v-erbB; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Phosphotransferases; Rats; Retroviridae Proteins, Oncogenic; Second Messenger Systems; Sequence Homology, Nucleic Acid | 1990 |
Sulphate induces very fast cell rounding and detachment.
Topics: Cell Line; Cell Membrane; Cells; Diglycerides; Endocytosis; Glycosaminoglycans; Humans; Hymecromone; Inositol 1,4,5-Trisphosphate; Nitrophenols; Second Messenger Systems; Sulfates; Tumor Cells, Cultured | 1991 |
Phospholipase D and phospholipase C in human cholinergic neuroblastoma (LA-N-2) cells: modulation by muscarinic agonists and protein kinase C.
Topics: Atropine; Diglycerides; Enzyme Activation; Humans; Inositol 1,4,5-Trisphosphate; Neuroblastoma; Parasympathomimetics; Phospholipase D; Protein Kinase C; Second Messenger Systems; Tumor Cells, Cultured; Type C Phospholipases | 1990 |
Regulation of 1,2-diacylglycerol production by angiotensin-II in bovine adrenal glomerulosa cells.
Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Animals; Calcium; Calcium Channels; Cattle; Cells, Cultured; Cycloheximide; Diglycerides; Glycerides; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Nickel; Nifedipine; Pertussis Toxin; Virulence Factors, Bordetella; Zona Glomerulosa | 1990 |
Endothelin receptor-coupling mechanisms in vascular smooth muscle: a role for protein kinase C.
Topics: Alkaloids; Animals; Calcium; Cells, Cultured; Diglycerides; Drug Interactions; Egtazic Acid; Endothelins; Inositol 1,4,5-Trisphosphate; Muscle, Smooth, Vascular; Peptides; Protein Kinase C; Rats; Receptors, Cell Surface; Receptors, Endothelin; Staurosporine; Vasoconstriction; Vasoconstrictor Agents | 1990 |
The temporal relationship between phospholipase activation, diradylglycerol formation and superoxide production in the human neutrophil.
Topics: Choline; Diglycerides; Enzyme Activation; Humans; Inositol 1,4,5-Trisphosphate; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidylinositol Diacylglycerol-Lyase; Phospholipase D; Phosphoric Diester Hydrolases; Superoxides | 1990 |
Effects of substance P on inositol triphosphate accumulation, on contractile responses and on arachidonic acid release and prostaglandin biosynthesis in rabbit iris sphincter muscle.
Topics: Animals; Arachidonic Acids; Diglycerides; Dinoprostone; Dose-Response Relationship, Drug; Female; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Iris; Male; Muscle Contraction; Muscle, Smooth; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Phospholipids; Prostaglandins E; Prostaglandins F; Rabbits; Substance P | 1986 |
Parathyroid hormone inhibition of Na+/phosphate cotransport in OK cells: generation of second messengers in the regulatory cascade.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Biological Transport; Calcium; Cell Line; Cyclic AMP; Diglycerides; Dose-Response Relationship, Drug; Enzyme Activation; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kidney; Opossums; Parathyroid Hormone; Phosphates; Second Messenger Systems; Sodium; Type C Phospholipases | 1989 |
Endothelin-induced biphasic formation of 1,2-diacylglycerol in cultured rabbit vascular smooth muscle cells--mass analysis with a radioenzymatic assay.
Topics: Animals; Cells, Cultured; Diacylglycerol Kinase; Diglycerides; Endothelins; Endothelium, Vascular; Glycerides; Hydrolysis; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kidney; Male; Muscle, Smooth, Vascular; Peptides; Phosphatidylinositols; Phosphotransferases; Rabbits; Rats | 1989 |
Quantitative changes in polyphosphoinositides 1,2-diacylglycerol and inositol 1,4,5-trisphosphate by platelet-derived growth factor and prostaglandin F2 alpha.
Topics: Animals; Antibodies, Monoclonal; Antibody Specificity; Binding Sites, Antibody; Cattle; Cell Line; Diglycerides; Dinoprost; Glycerides; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Mice; Mice, Inbred BALB C; Phosphatidylinositols; Platelet-Derived Growth Factor; Sugar Phosphates; Swine | 1989 |
Role of inositol lipid second messengers in regulation of secretion: studies of thyrotropin-releasing hormone action in pituitary cells.
Topics: Animals; Clone Cells; Diglycerides; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Models, Biological; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Pituitary Gland; Prolactin; Rats; Second Messenger Systems; Sugar Phosphates; Thyrotropin-Releasing Hormone | 1989 |
Role of phosphoinositide metabolites in the prolongation of afterhyperpolarizations by alpha 1-adrenoceptors in rat dorsal raphe neurons.
Topics: Action Potentials; Animals; Cells, Cultured; Diglycerides; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Neurons; Norepinephrine; Phenylephrine; Phorbol Esters; Phosphatidylinositols; Propranolol; Raphe Nuclei; Rats; Receptors, Adrenergic; Sympathomimetics; Tetrodotoxin | 1987 |
Hydrolysis of inositol lipids: an early signal of human cytomegalovirus infection.
Topics: Antigens, Viral; Blood; Complement C3; Culture Media; Cytomegalovirus Infections; Diglycerides; Electrolytes; Glycerides; Hot Temperature; Humans; Hydrolysis; Immediate-Early Proteins; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Lung; Papaverine; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Sugar Phosphates | 1988 |
Receptor-stimulated inositol phospholipid hydrolysis and neural function.
Topics: Animals; Brain; Diglycerides; Erythrocytes; Hydrolysis; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Neurotransmitter Agents; Phosphatidylinositol Phosphates; Phosphatidylinositols; Protein Kinase C; Rats; Receptors, Neurotransmitter | 1986 |
ras-transformed cells: altered levels of phosphatidylinositol-4,5-bisphosphate and catabolites.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Diglycerides; Humans; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Oncogenes; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Rats | 1986 |
Thyrotropin-releasing hormone stimulation of polyphosphoinositide hydrolysis in GH3 cell membranes is GTP dependent but insensitive to cholera or pertussis toxin.
Topics: Animals; Cell Line; Cell Membrane; Cholera Toxin; Diglycerides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Hydrolysis; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Phosphatidylinositol Phosphates; Phosphatidylinositols; Pituitary Gland; Pituitary Neoplasms; Rats; Thionucleotides; Thyrotropin-Releasing Hormone | 1986 |
The effects of bombesin on polyphosphoinositide and calcium metabolism in Swiss 3T3 cells.
Topics: 3-O-Methylglucose; Animals; Bombesin; Calcium; Cell Line; Diglycerides; Fibroblasts; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Methylglucosides; Mice; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Phosphates; Phosphatidylinositols | 1987 |
Secretin induces rapid increases in inositol trisphosphate, cytosolic Ca2+ and diacylglycerol as well as cyclic AMP in rat pancreatic acini.
Topics: Animals; Calcium; Carbachol; Cyclic AMP; Diglycerides; Glycerides; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Male; Pancreas; Rats; Rats, Inbred Strains; Secretin; Sugar Phosphates | 1986 |
Phosphoinositide turnover during hepatocarcinogenesis induced by N-nitrosodiethylamine.
Topics: 1-Phosphatidylinositol 4-Kinase; Animals; Diacylglycerol Kinase; Diethylnitrosamine; Diglycerides; Inositol 1,4,5-Trisphosphate; Liver Neoplasms, Experimental; Male; Phosphatidylinositols; Phosphotransferases (Alcohol Group Acceptor); Rats; Rats, Wistar | 1995 |
Effect of okadaic acid on histamine release from rat peritoneal mast cells activated by anti-IgE.
Topics: Animals; Antibodies, Anti-Idiotypic; Calcimycin; Calcium; Diglycerides; Ethers, Cyclic; Histamine Release; Hydrolysis; Inositol 1,4,5-Trisphosphate; Mast Cells; Okadaic Acid; p-Methoxy-N-methylphenethylamine; Peritoneal Cavity; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Phosphates; Rats; Rats, Wistar; Second Messenger Systems; Stimulation, Chemical | 1993 |
Role of 1,2-sn diacylglycerol in airway smooth muscle stimulated by carbachol.
Topics: Adenylyl Cyclases; Animals; Carbachol; Cattle; Diglycerides; Dose-Response Relationship, Drug; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Isoproterenol; Muscle Contraction; Muscle, Smooth; Second Messenger Systems; Stimulation, Chemical; Time Factors; Trachea | 1995 |
Stimulation of interleukin-6 production by endothelin in rat bone marrow-derived stromal cells.
Topics: Animals; Base Sequence; Bone Marrow; Cells, Cultured; Diglycerides; Endothelins; Enzyme Activation; Inositol 1,4,5-Trisphosphate; Interleukin-6; Ionomycin; Male; Molecular Sequence Data; Rats; Rats, Inbred F344; Receptors, Endothelin; RNA, Messenger; Second Messenger Systems; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1994 |
Collagen type IV stimulates an increase in intracellular Ca2+ in pancreatic acinar cells via activation of phospholipase C.
Topics: Amino Acid Sequence; Animals; Calcium; Collagen; Diglycerides; Enzyme Activation; Female; Inositol 1,4,5-Trisphosphate; Male; Molecular Sequence Data; Oligopeptides; Pancreas; Phosphatidylinositols; Rats; Rats, Wistar; Signal Transduction; Type C Phospholipases | 1994 |
Modulation of signalling initiated by phosphoinositidase-C-linked receptors.
Topics: Animals; Calcium; CHO Cells; Cricetinae; Diglycerides; Down-Regulation; Humans; Inositol 1,4,5-Trisphosphate; Phosphatidylinositols; Phosphoric Diester Hydrolases; Receptors, Cell Surface; Signal Transduction | 1993 |
Quantification of inositol phospholipid breakdown in isolated rat hepatocytes.
Topics: Animals; Diglycerides; Ethanol; Hydrolysis; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Lithium; Liver; Male; Phosphatidic Acids; Phosphatidylinositols; Rats; Rats, Sprague-Dawley; Vasopressins | 1993 |
Evidence for coupling of Clostridium perfringens alpha-toxin-induced hemolysis to stimulated phosphatidic acid formation in rabbit erythrocytes.
Topics: Animals; Bacterial Toxins; Calcium-Binding Proteins; Clostridium perfringens; Diglycerides; Erythrocytes; Hemolysis; Inositol 1,4,5-Trisphosphate; Phosphatidic Acids; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Rabbits; Temperature; Type C Phospholipases | 1993 |
Different endothelin receptor subtypes are involved in phospholipid signalling in the proximal tubule of rat kidney.
Topics: Animals; Biological Transport; Diglycerides; Endothelins; Humans; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Kidney Cortex; Kidney Tubules, Proximal; Male; Phospholipids; Phosphorylcholine; Protein Kinase C; Rats; Rats, Wistar; Receptors, Endothelin; Signal Transduction; Swine; Viper Venoms | 1996 |
Influence of alimentary zinc deficiency on the concentration of the second messengers D-myo-inositol-1,4,5-trisphosphate (IP3) and s,n-1,2-diacylglycerol (DAG) in testes and brain of force-fed rats.
Topics: Animals; Brain; Caseins; Diet; Diglycerides; Enteral Nutrition; Inositol 1,4,5-Trisphosphate; Male; Rats; Rats, Sprague-Dawley; Testis; Tissue Distribution; Type C Phospholipases; Zinc | 1996 |
Alpha 1-adrenoceptor activation of a non-selective cation current in rabbit portal vein by 1,2-diacyl-sn-glycerol.
Topics: Alkaloids; Animals; Benzophenanthridines; Carcinogens; Cyclohexanones; Diglycerides; Enzyme Inhibitors; Estrenes; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Inositol 1,4,5-Trisphosphate; Lipoprotein Lipase; Norepinephrine; Phenanthridines; Phorbol 12,13-Dibutyrate; Phosphodiesterase Inhibitors; Portal Vein; Pyrrolidinones; Rabbits; Receptors, Adrenergic, alpha-1; Thionucleotides; Type C Phospholipases | 1997 |
sn-1,2-diacylglycerol and choline increase after fertilization in Xenopus laevis.
Topics: Animals; Biological Transport; Calcium; Cell Membrane; Choline; Diglycerides; Embryo, Nonmammalian; Female; Fertilization; Inositol 1,4,5-Trisphosphate; Insemination; Ionomycin; Male; Ovum; Phosphorylcholine; Protein Kinase C; Spermatozoa; Time Factors; Xenopus laevis; Zygote | 1997 |
Disruption by lithium of phosphoinositide signalling in cerebellar granule cells in primary culture.
Topics: Animals; Carbachol; Cells, Cultured; Cerebellum; Diglycerides; Extracellular Space; Inositol; Inositol 1,4,5-Trisphosphate; Lithium; Muscarinic Agonists; Neurons; Phosphatidylinositols; Potassium Chloride; Rats; Signal Transduction | 1998 |
HDL3-mediated inhibition of thrombin-induced platelet aggregation and fibrinogen binding occurs via decreased production of phosphoinositide-derived second messengers 1,2-diacylglycerol and inositol 1,4,5-tris-phosphate.
Topics: Adult; Antigens, CD; Blood Platelets; Calcium; Cell Membrane; Coagulants; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Diglycerides; Fibrinogen; Humans; Inositol 1,4,5-Trisphosphate; Intracellular Fluid; Lipoproteins, HDL; Middle Aged; Phosphatidic Acids; Phosphatidylinositol 4,5-Diphosphate; Phosphorylation; Platelet Activation; Platelet Aggregation; Protein Kinase C; Second Messenger Systems; Substrate Specificity; Thrombin; Time Factors | 1998 |
17beta-oestradiol increases intracellular Ca2+ concentration in rat enterocytes. Potential role of phospholipase C-dependent store-operated Ca2+ influx.
Topics: Animals; Calcium; Cells, Cultured; Diglycerides; Duodenum; Enzyme Activation; Enzyme Inhibitors; Estradiol; Estrenes; Female; Inositol 1,4,5-Trisphosphate; Protein Kinase C; Pyrrolidinones; Rats; Rats, Wistar; Type C Phospholipases | 1999 |
S-carboxymethylcysteine inhibits neutrophil activation mediated by N-formyl-methionyl-leucyl-phenylalanine.
Topics: Carbocysteine; Cell Adhesion; Cell-Free System; Chemotaxis, Leukocyte; Cyclic AMP; Diglycerides; GTP-Binding Proteins; Humans; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Type C Phospholipases | 2002 |
Effect of CD40--CD40 ligand interaction on diacylglycerol-protein kinase C and inositol trisphosphate-Ca(2+) signal transduction pathway in human umbilical vein endothelial cells.
Topics: Antibodies, Monoclonal; Calcium; CD40 Antigens; CD40 Ligand; Cytosol; Diglycerides; Dose-Response Relationship, Drug; Endothelial Cells; Humans; Inositol 1,4,5-Trisphosphate; Kinetics; Protein Kinase C; Signal Transduction; Umbilical Veins | 2003 |
Phospholipase C, but not InsP3 or DAG, -dependent activation of the muscarinic receptor-operated cation current in guinea-pig ileal smooth muscle cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclase Inhibitors; Animals; Aristolochic Acids; Bridged-Ring Compounds; Caffeine; Calcium; Carbachol; Diglycerides; Estrenes; Guanosine Triphosphate; Guinea Pigs; Ileum; Indoles; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Isoenzymes; Isoproterenol; Male; Membrane Potentials; Muscle, Smooth; Norbornanes; Patch-Clamp Techniques; Phospholipase C beta; Phospholipases A; Pyrrolidinones; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Ryanodine; Thiocarbamates; Thiones; Type C Phospholipases | 2004 |
Clostridium perfringens alpha-toxin activates the sphingomyelin metabolism system in sheep erythrocytes.
Topics: 4-Aminobenzoic Acid; ADP Ribose Transferases; Amidohydrolases; Animals; Bacterial Toxins; Botulinum Toxins; Calcium-Binding Proteins; Ceramidases; Chromatography, Thin Layer; Diglycerides; Dose-Response Relationship, Drug; Endocannabinoids; Enzyme Inhibitors; Erythrocytes; Ethanolamines; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Hemolysis; Inositol 1,4,5-Trisphosphate; Lysophospholipids; Oleic Acids; para-Aminobenzoates; Pertussis Toxin; Phosphatidylcholines; Phosphorylcholine; Phosphotransferases (Alcohol Group Acceptor); Rabbits; Sheep; Sphingomyelins; Sphingosine; Time Factors; Toxins, Biological; Type C Phospholipases | 2004 |
Phospholipase C gene expression, protein content, and activities in cardiac hypertrophy and heart failure due to volume overload.
Topics: Animals; Cardiac Output, Low; Cardiomegaly; Cytosol; Diglycerides; Gene Expression; Hyperemia; Inositol 1,4,5-Trisphosphate; Isoenzymes; Male; Phosphatidylinositol 4,5-Diphosphate; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sarcolemma; Type C Phospholipases; Ventricular Function, Left | 2004 |
Amplification of Ca2+ signaling by diacylglycerol-mediated inositol 1,4,5-trisphosphate production.
Topics: Animals; Calcium; Calcium Channels; Calcium Signaling; CHO Cells; Cricetinae; Diglycerides; HeLa Cells; Humans; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Receptors, Cytoplasmic and Nuclear; src-Family Kinases; Type C Phospholipases | 2005 |
Honokiol-induced neurite outgrowth promotion depends on activation of extracellular signal-regulated kinases (ERK1/2).
Topics: Animals; Benzylamines; Biphenyl Compounds; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Cerebral Cortex; Chromones; Diglycerides; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Enzyme Activation; Female; Fetus; Flavonoids; Inositol 1,4,5-Trisphosphate; Lignans; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Models, Biological; Morpholines; Neurites; Neurons; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Pregnancy; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Sulfonamides | 2005 |
Evidence that phospholipase-C-dependent, calcium-independent mechanisms are required for directional migration of T-lymphocytes in response to the CCR4 ligands CCL17 and CCL22.
Topics: Acetophenones; Benzopyrans; Calcium; Calcium Channels; Calcium Signaling; Catalytic Domain; Cell Line, Tumor; Chemokine CCL17; Chemokine CCL22; Chemokines, CC; Chemotaxis; Chromones; Diglycerides; Estrenes; Humans; Indoles; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Leukemia-Lymphoma, Adult T-Cell; Morpholines; Pertussis Toxin; Phosphatidylinositol 3-Kinases; Phosphatidylinositol Diacylglycerol-Lyase; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Phosphothreonine; Protein Processing, Post-Translational; Pyrroles; Pyrrolidinones; Receptors, CCR4; Receptors, Chemokine; Receptors, Cytoplasmic and Nuclear; Recombinant Fusion Proteins; T-Lymphocytes; Th2 Cells | 2006 |
The mood stabilizer valproate inhibits both inositol- and diacylglycerol-signaling pathways in Caenorhabditis elegans.
Topics: Acetylcholine; Animals; Antimanic Agents; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Carrier Proteins; Defecation; Diglycerides; Inositol; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Inositol Phosphates; Muscle Contraction; Mutation; Ovulation; Phosphatidylinositol 4,5-Diphosphate; Signal Transduction; Valproic Acid | 2008 |
OX40-OX40 ligand interaction may activate phospholipase C signal transduction pathway in human umbilical vein endothelial cells.
Topics: Calcium; Cells, Cultured; Diglycerides; Dose-Response Relationship, Drug; Endothelial Cells; Endothelium, Vascular; Humans; Inositol 1,4,5-Trisphosphate; OX40 Ligand; Protein Binding; Receptors, OX40; Signal Transduction; Time Factors; Type C Phospholipases; Umbilical Veins | 2009 |
Sprouty proteins inhibit receptor-mediated activation of phosphatidylinositol-specific phospholipase C.
Topics: Adaptor Proteins, Signal Transducing; Animals; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Biomarkers; Calcium; Diglycerides; Enzyme Activation; Immunoprecipitation; Inositol 1,4,5-Trisphosphate; Intracellular Signaling Peptides and Proteins; Intracellular Space; Lectins, C-Type; Membrane Proteins; Mice; Mitogen-Activated Protein Kinases; NIH 3T3 Cells; Phospholipase C gamma; Phosphoproteins; Protein Binding; Protein Serine-Threonine Kinases; ras Proteins; Receptors, Antigen, T-Cell; T-Lymphocytes; Transcription, Genetic | 2010 |
Changes in the inositol lipid signal system and effects on the secretion of TNF-α by macrophages in severely scalded mice.
Topics: Animals; Burns; Calcium; Diglycerides; Inositol 1,4,5-Trisphosphate; Macrophages; Mice; Models, Animal; Peritoneum; Phosphatidylinositols; Protein Kinase C; Tumor Necrosis Factor-alpha | 2011 |
Responsiveness of vomeronasal cells to a newt peptide pheromone, sodefrin as monitored by changes of intracellular calcium concentrations.
Topics: Animals; Calcium; Calcium Signaling; Cell Proliferation; Diglycerides; Epithelial Cells; Estradiol; Female; Hypophysectomy; Inositol 1,4,5-Trisphosphate; Male; Molecular Imaging; Oligopeptides; Ovariectomy; Ovary; Pituitary Gland; Primary Cell Culture; Prolactin; Protein Kinase C; Salamandridae; Sex Attractants; Sexual Behavior, Animal; Species Specificity; Vomeronasal Organ | 2013 |
The effect of CD137-CD137 ligand interaction on phospholipase C signaling pathway in human endothelial cells.
Topics: 4-1BB Ligand; Antibodies; Calcium; Diglycerides; Human Umbilical Vein Endothelial Cells; Humans; Inositol 1,4,5-Trisphosphate; Interleukin-6; Protein Interaction Maps; Signal Transduction; Tumor Necrosis Factor Receptor Superfamily, Member 9; Tumor Necrosis Factor-alpha; Type C Phospholipases | 2013 |
Diacylglycerol mediates regulation of TASK potassium channels by Gq-coupled receptors.
Topics: Amino Acid Motifs; Animals; Calcium; Cell Line; Diglycerides; GTP-Binding Protein alpha Subunits; GTP-Binding Protein alpha Subunits, Gq-G11; Humans; Inositol 1,4,5-Trisphosphate; Mice; Nerve Tissue Proteins; Phosphatidylinositol 4,5-Diphosphate; Potassium Channels, Tandem Pore Domain; Protein Kinase C; Signal Transduction; Type C Phospholipases | 2014 |