Page last updated: 2024-08-17

methacholine chloride and endothelin-1

methacholine chloride has been researched along with endothelin-1 in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's16 (66.67)18.2507
2000's4 (16.67)29.6817
2010's2 (8.33)24.3611
2020's2 (8.33)2.80

Authors

AuthorsStudies
Fernandes, LB; Goldie, RG; Henry, PJ; Knott, PG; McWilliam, AS; Rigby, PJ1
Martin, JG; Zacour, ME1
Aoki, T; Fukuchi, Y; Matsui, H; Nagase, T; Ouchi, Y1
Chalmers, GW; Little, SA; Patel, KR; Thomson, NC1
Aoki, T; Fukuchi, Y; Kurihara, H; Kurihara, Y; Nagase, T; Ouchi, Y; Yazaki, Y1
Clayton, RA; McGrath, JC; Nally, JE; Thomson, NC1
Irokawa, T; Kakuta, Y; Nara, M; Oshiro, T; Sasaki, T; Shimura, S; Shirato, K1
Harada, K; Kawahara, J; Kusaka, M; Okada, Y; Tokiwa, T; Uzumaki, H1
Assefa, D; Davidson, JS; Forrest-Owen, W; Hislop, J; McArdle, CA; Nahorski, SR; Willars, GB1
Held, HD; Martin, C; Uhlig, S1
Jankowska, R; Passowicz-Muszyńska, E; Szeliga, W1
Chalmers, GW; Little, SA; MacLeod, KJ; McSharry, C; Patel, KR; Thomson, LJ; Thomson, NC1
Clayton, RA; MacLean, MR; McGrath, JC; Nally, JE; Thomson, NC1
Aoki-Nagase, T; Kurihara, H; Kurihara, Y; Nagai, R; Nagase, T; Ouchi, Y1
Bialecki, R; Caccese, R; Graham, A1
Lindberg, S; Runer, T1
Held, HD; Uhlig, S1
Bochnowicz, S; Hart, T; Hay, DW; Louden, C; Luttmann, MA; Osborn, RR; Underwood, DC1
Brown, AJ; Nally, JE1
Jancar, S; Landgraf, RG1
Bourke, JE; Donovan, C; FitzPatrick, M1
Alexander, LM; Fujii, N; Halili, L; Kenny, GP; Singh, MS1
Hennenberg, M; Huang, R; Stief, CG; Strittmatter, F; Tamalunas, A; Waidelich, R1
Ciotkowska, A; Hennenberg, M; Huang, R; Kolben, T; Ledderose, S; Liu, Y; Magistro, G; Rutz, B; Schulz, H; Springer, F; Stief, CG; Tamalunas, A; Vigodski, V; Wang, R; Wendt, A1

Trials

3 trial(s) available for methacholine chloride and endothelin-1

ArticleYear
Endothelin-1-induced bronchoconstriction in asthma.
    American journal of respiratory and critical care medicine, 1997, Volume: 156, Issue:2 Pt 1

    Topics: Adult; Aerosols; Asthma; Bronchoconstriction; Bronchoconstrictor Agents; Double-Blind Method; Endothelin-1; Female; Humans; Male; Methacholine Chloride; Middle Aged; Respiratory Function Tests; Single-Blind Method; Statistics, Nonparametric; Time Factors

1997
[Endothelin concentration in sera of patients with atopic bronchial asthma].
    Pneumonologia i alergologia polska, 1999, Volume: 67, Issue:1-2

    Topics: Adult; Asthma; Bronchi; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Endothelin-1; Humans; Methacholine Chloride; Muscle, Smooth

1999
Sputum cellular and cytokine responses to inhaled endothelin-1 in asthma.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 1999, Volume: 29, Issue:11

    Topics: Adult; Albumins; Asthma; Bronchial Provocation Tests; Bronchoconstrictor Agents; Cell Count; Cross-Over Studies; Cytokines; Double-Blind Method; Endothelin-1; Female; Humans; Interleukin-1; Male; Methacholine Chloride; Middle Aged; Nitric Oxide; Sputum; Tumor Necrosis Factor-alpha

1999

Other Studies

21 other study(ies) available for methacholine chloride and endothelin-1

ArticleYear
Influence of parainfluenza-1 respiratory tract viral infection on endothelin receptor-effector systems in mouse and rat tracheal smooth muscle.
    British journal of pharmacology, 1996, Volume: 119, Issue:2

    Topics: Animals; Endothelin Receptor Antagonists; Endothelin-1; In Vitro Techniques; Male; Methacholine Chloride; Mice; Mice, Inbred CBA; Muscle Contraction; Muscle, Smooth; Parainfluenza Virus 1, Human; Peptides, Cyclic; Rats; Rats, Wistar; Receptor, Endothelin A; Receptor, Endothelin B; Receptors, Endothelin; Respiratory Tract Infections; Respirovirus Infections; Time Factors; Trachea; Vasoconstrictor Agents; Viper Venoms

1996
Enhanced growth response of airway smooth muscle in inbred rats with airway hyperresponsiveness.
    American journal of respiratory cell and molecular biology, 1996, Volume: 15, Issue:5

    Topics: Airway Resistance; Animals; Blood; Bronchoconstrictor Agents; Cattle; Cell Cycle; Cell Division; Cells, Cultured; Culture Techniques; Endothelin-1; Humans; Insulin; Male; Methacholine Chloride; Mitogens; Muscle, Smooth; Platelet-Derived Growth Factor; Rats; Rats, Inbred F344; Rats, Inbred Lew; Serotonin; Swine; Trachea

1996
Lung tissue behavior in the mouse during constriction induced by methacholine and endothelin-1.
    Journal of applied physiology (Bethesda, Md. : 1985), 1996, Volume: 81, Issue:6

    Topics: Airway Resistance; Animals; Dose-Response Relationship, Drug; Endothelin-1; Lung; Male; Methacholine Chloride; Mice; Mice, Inbred ICR

1996
Airway hyperresponsiveness to methacholine in mutant mice deficient in endothelin-1.
    American journal of respiratory and critical care medicine, 1998, Volume: 157, Issue:2

    Topics: Airway Resistance; Animals; Endothelin-1; Enzyme Inhibitors; Lung; Methacholine Chloride; Mice; Mice, Knockout; Nitric Oxide Synthase; omega-N-Methylarginine; Ovalbumin; Respiratory Hypersensitivity; Serotonin

1998
Interactions between endothelin-I-induced contractions and bronchodilators in human isolated bronchi.
    Clinical science (London, England : 1979), 1997, Volume: 93, Issue:6

    Topics: Albuterol; Atrial Natriuretic Factor; Bronchoconstriction; Bronchoconstrictor Agents; Bronchodilator Agents; Dose-Response Relationship, Drug; Endothelin-1; Humans; Isosorbide Dinitrate; Methacholine Chloride; Nitroprusside

1997
Effects of histamine and endothelin-1 on membrane potentials and ion currents in bovine tracheal smooth-muscle cells.
    American journal of respiratory cell and molecular biology, 1998, Volume: 19, Issue:5

    Topics: Acetylcholine; Animals; Cattle; Cells, Cultured; Cholinergic Agonists; Electrophysiology; Endothelin-1; Histamine; Ion Channels; Membrane Potentials; Methacholine Chloride; Muscle, Smooth, Vascular; Patch-Clamp Techniques; Quaternary Ammonium Compounds; Trachea

1998
Effects of KRN4884 (a novel K+ channel opener), levcromakalim, nilvadipine and propranolol on endothelin-1-induced heart disorders in anesthetized rats.
    Japanese journal of pharmacology, 1998, Volume: 78, Issue:3

    Topics: Anesthesia; Animals; Antihypertensive Agents; Blood Pressure; Bronchoconstrictor Agents; Cromakalim; Electrocardiography; Endothelin-1; Heart Diseases; Heart Rate; Injections, Intra-Arterial; Male; Methacholine Chloride; Nifedipine; Potassium Channels; Propranolol; Pyridines; Rats; Rats, Wistar

1998
The lack of gonadotrophin-releasing hormone (GnRH) receptor desensitisation in alphaT3-1 cells is not due to GnRH receptor reserve or phosphatidylinositol 4,5-bis-phosphate pool size.
    Molecular and cellular endocrinology, 1999, Jan-25, Volume: 147, Issue:1-2

    Topics: Animals; Buserelin; Calcium; Cell Line; Down-Regulation; Endothelin-1; Gonadotropin-Releasing Hormone; GTP-Binding Proteins; Humans; Inositol Phosphates; Kinetics; Lithium Chloride; Methacholine Chloride; Mice; Oxytocin; Phosphatidylinositol 4,5-Diphosphate; Photoaffinity Labels; Receptor, Muscarinic M3; Receptors, Cell Surface; Receptors, LHRH; Receptors, Muscarinic; Type C Phospholipases; Uridine Triphosphate

1999
Characterization of airway and vascular responses in murine lungs.
    British journal of pharmacology, 1999, Volume: 126, Issue:5

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine; Animals; Bombesin; Bronchoconstriction; Bronchoconstrictor Agents; Dose-Response Relationship, Drug; Endothelin-1; Female; Histidine; In Vitro Techniques; Leukotriene C4; Lung; Methacholine Chloride; Mice; Mice, Inbred BALB C; Perfusion; Platelet Activating Factor; Serotonin; Substance P; Vasoconstriction; Vasoconstrictor Agents

1999
Chronic exposure to hypoxia attenuates contractile responses in rat airways in vitro: a possible role for nitric oxide.
    European journal of pharmacology, 1999, Nov-26, Volume: 385, Issue:1

    Topics: Albuterol; Animals; Bronchi; Bronchoconstrictor Agents; Bronchodilator Agents; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Endothelin-1; Enzyme Inhibitors; Epithelium; Hypoxia; In Vitro Techniques; Indomethacin; Male; Methacholine Chloride; Muscle Contraction; Muscle Relaxation; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Potassium Chloride; Rats; Rats, Wistar; Trachea

1999
Disruption of ET-1 gene enhances pulmonary responses to methacholine via functional mechanism in knockout mice.
    Journal of applied physiology (Bethesda, Md. : 1985), 1999, Volume: 87, Issue:6

    Topics: Airway Resistance; Animals; Bronchoconstrictor Agents; Drug Resistance; Elasticity; Endothelin-1; Lung; Methacholine Chloride; Mice; Mice, Knockout; Serotonin

1999
Pharmacological characterization of mucin secretion from CHO-K1-hNK(1)R cells.
    Neuropeptides, 1999, Volume: 33, Issue:3

    Topics: Angiotensin II; Animals; Benzamides; Biological Transport; CHO Cells; Cricetinae; Endothelin-1; Glucosamine; Humans; Methacholine Chloride; Mucins; Muscarinic Agonists; Neurokinin A; Peptide Fragments; Phenylephrine; Piperidines; Quinuclidines; Receptors, Neurokinin-1; Serotonin; Substance P; Transfection; Tritium; Vasoconstrictor Agents

1999
Ciliostimulatory effects mediated by nitric oxide.
    Acta oto-laryngologica, 1999, Volume: 119, Issue:7

    Topics: Adenoids; Bucladesine; Child; Child, Preschool; Cilia; Dibutyryl Cyclic GMP; Endothelin-1; Enzyme Inhibitors; Humans; In Vitro Techniques; Methacholine Chloride; Mucociliary Clearance; Nitric Oxide; Nitroarginine; Stimulation, Chemical; Substance P; Terbutaline

1999
Basal lung mechanics and airway and pulmonary vascular responsiveness in different inbred mouse strains.
    Journal of applied physiology (Bethesda, Md. : 1985), 2000, Volume: 88, Issue:6

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Bronchoconstrictor Agents; Endothelin-1; In Vitro Techniques; Lung; Methacholine Chloride; Mice; Mice, Inbred Strains; Pulmonary Circulation; Respiratory Mechanics; Vasoconstrictor Agents

2000
Differences in time-related cardiopulmonary responses to hypoxia in three rat strains.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2000, Volume: 22, Issue:5

    Topics: Altitude; Animals; Carbachol; Disease Models, Animal; Endothelin-1; Endothelins; Hypertension, Pulmonary; Hypertrophy; Hypertrophy, Right Ventricular; Hypoxia; In Vitro Techniques; Male; Methacholine Chloride; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Rats, Wistar; Species Specificity; Trachea; Vasoconstriction; Vasodilation

2000
Hydrocortisone abolishes the angiotensin II-mediated potentiation of endothelin-1 in bovine bronchi.
    Clinical science (London, England : 1979), 2001, Volume: 100, Issue:1

    Topics: Angiotensin II; Animals; Anti-Inflammatory Agents; Bronchoconstriction; Bronchoconstrictor Agents; Cattle; Culture Techniques; Dose-Response Relationship, Drug; Drug Synergism; Endothelin-1; Hydrocortisone; Methacholine Chloride

2001
The role of endothelin pathway in modulation of airway reactivity to methacholine in C57Bl/6 and BALB/c mice.
    European journal of pharmacology, 2008, Aug-20, Volume: 590, Issue:1-3

    Topics: Animals; Endothelin-1; Endothelins; Lung; Male; Methacholine Chloride; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Oligopeptides; Peptides, Cyclic; Piperidines; Signal Transduction; Species Specificity

2008
Prostaglandin E2 elicits greater bronchodilation than salbutamol in mouse intrapulmonary airways in lung slices.
    Pulmonary pharmacology & therapeutics, 2014, Volume: 28, Issue:1

    Topics: Adrenergic beta-2 Receptor Agonists; Albuterol; Animals; Asthma; Bronchodilator Agents; Calcium; Dinoprostone; Endothelin-1; Lung; Male; Methacholine Chloride; Mice; Mice, Inbred BALB C; Serotonin

2014
Endothelin-1 modulates methacholine-induced cutaneous vasodilatation but not sweating in young human skin.
    The Journal of physiology, 2016, 06-15, Volume: 594, Issue:12

    Topics: Adolescent; Adult; Endothelin-1; Female; Humans; Male; Methacholine Chloride; Nitroprusside; Skin; Skin Physiological Phenomena; Sweating; Vasodilation; Vasodilator Agents; Young Adult

2016
Inhibition of Full Smooth Muscle Contraction in Isolated Human Detrusor Tissues by Mirabegron Is Limited to Off-Target Inhibition of Neurogenic Contractions.
    The Journal of pharmacology and experimental therapeutics, 2022, Volume: 381, Issue:2

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetanilides; Carbachol; Endothelin-1; Female; Humans; Male; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Receptors, Adrenergic; Thiazoles; Urinary Bladder, Overactive

2022
Permixon®, hexane-extracted Serenoa repens, inhibits human prostate and bladder smooth muscle contraction and exerts growth-related functions in human prostate stromal cells.
    Life sciences, 2022, Nov-01, Volume: 308

    Topics: Actins; Adrenergic Agents; Endothelin-1; Hexanes; Humans; Male; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Phalloidine; Plant Extracts; Prostate; Prostatic Hyperplasia; Serenoa; Sincalide; Stromal Cells; Thromboxanes; Urinary Bladder

2022