metformin has been researched along with ursodeoxycholic acid in 24 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (29.17) | 29.6817 |
| 2010's | 15 (62.50) | 24.3611 |
| 2020's | 2 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Darvesh, AS; Geldenhuys, WJ; Leeper, TC; Morris, DL; Sullivan, PG; Yonutas, HM | 1 |
| Bischoff, A | 1 |
| Bugianesi, E; Marchesini, G; Marzocchi, R; Villanova, N | 1 |
| Comar, KM; Sterling, RK | 1 |
| Galle, PR; Siebler, J | 1 |
| Harrison, SA; Kashi, MR; Torres, DM | 1 |
| Dhawan, A; Dziechciarz, P; Horvath, A; Socha, P; Szajewska, H; Vajro, P | 1 |
| Álvarez Ferre, J; González Jiménez, E; Schmidt Río-Valle, J | 1 |
| Henry, L; Mehta, R; Mishra, A; Reyes, MJ; Younossi, ZM | 1 |
| Ganesh, S; Rustgi, VK | 1 |
| Antebi, A; Astle, CM; Bogue, M; de Magalhães, JP; Denzel, MS; Fernandez, E; Flurkey, K; Hamilton, KL; Harrison, DE; Javors, MA; Lamming, DW; Martinez, PA; McCord, JM; Miller, BF; Miller, RA; Müller, M; Nadon, NL; Ndukum, J; Nelson, JF; Rainger, GE; Richardson, A; Sabatini, DM; Salmon, AB; Simpkins, JW; Steegenga, WT; Strong, R | 1 |
| Cahen, DL; Diamant, M; Groen, AK; Hoekstra, T; Kramer, MH; Muskiet, MH; Nieuwdorp, M; Smits, MM; Tonneijck, L; van Raalte, DH | 1 |
| Ali, A; Elfituri, A; Shehata, H | 1 |
| Dehghanian, A; Dorvash, MR; Firouzabadi, N; Khoshnood, MJ; Mosaddeghi, P; Saber, H | 1 |
| Bisson, WH; Cai, J; Chen, B; Deng, Y; Gao, X; Ge, P; Gonzalez, FJ; Jiang, C; Krausz, KW; Lian, G; Liu, C; Liu, J; Nichols, RG; Patterson, AD; Rimal, B; Shi, J; Sun, L; Wang, G; Wang, X; Wu, Q; Wu, Y; Xia, J; Xie, C; Yun, C; Zhang, H; Zhang, S; Zhang, X | 1 |
| Cotrim, HP; Oliveira, CP; Parise, ER; Salgado, ALA; Siqueira, ACG; Stefano, JT | 1 |
| Atkin, SL; De Vincentis, A; Jamialahmadi, T; Mahjoubin-Tehran, M; Mantzoros, CS; Mikhailidis, DP; Sahebkar, A | 1 |
| Briley, A; Cruickshank, K; Lovell, H; Marschall, HU; Mitchell, A; Murphy, H; Ovadia, C; Pitrelli, N; Seed, P; Singh, C; Williamson, C | 1 |
10 review(s) available for metformin and ursodeoxycholic acid
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Non-alcoholic fatty liver disease/non-alcoholic steatohepatitis (NAFLD/NASH): treatment.
Topics: Antioxidants; Cholagogues and Choleretics; Cytoprotection; Enzyme Inhibitors; Fatty Liver; Humans; Hypoglycemic Agents; Hypolipidemic Agents; Lactones; Life Style; Lipase; Metformin; Orlistat; Phlebotomy; Thiazolidinediones; Ursodeoxycholic Acid | 2004 |
Review article: Drug therapy for non-alcoholic fatty liver disease.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antioxidants; Ascorbic Acid; Betaine; Cholagogues and Choleretics; Enzyme Inhibitors; Fatty Liver; Humans; Hypoglycemic Agents; Lipotropic Agents; Metformin; Pentoxifylline; Probucol; Thiazolidinediones; Ursodeoxycholic Acid; Vitamin E | 2006 |
Treatment of nonalcoholic fatty liver disease.
Topics: Alanine Transaminase; Animals; Antioxidants; Body Mass Index; Fatty Liver; Humans; Hypolipidemic Agents; Liver Transplantation; Metformin; Pioglitazone; Thiazolidinediones; Tumor Necrosis Factor-alpha; Ursodeoxycholic Acid; Weight Loss | 2006 |
Current and emerging therapies in nonalcoholic fatty liver disease.
Topics: Animals; Antioxidants; Bariatric Surgery; Body Mass Index; Cannabinoids; Cholagogues and Choleretics; Comorbidity; Fatty Liver; Glucagon-Like Peptide 1; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemic Agents; Insulin Resistance; Lactones; Life Style; Metformin; Obesity; Orlistat; Piperidines; Pyrazoles; Rimonabant; Thiazolidinediones; Treatment Outcome; Ursodeoxycholic Acid; Weight Loss | 2008 |
Pharmacological interventions for nonalcoholic fatty liver disease in adults and in children: a systematic review.
Topics: Acetylcysteine; Adult; Alanine Transaminase; Aspartate Aminotransferases; Carnitine; Child; Dietary Supplements; Drug Synergism; Drug Therapy, Combination; Fatty Liver; Humans; Hypoglycemic Agents; Liver; Metformin; Pioglitazone; Probucol; Randomized Controlled Trials as Topic; Thiazolidinediones; Ursodeoxycholic Acid; Vitamin E | 2009 |
[Fatty liver and its clinical management in obese adolescents].
Topics: Adiponectin; Adolescent; Apoptosis; Biomarkers; Chemokines; Disease Progression; Fatty Liver; Fibrosis; Hepatocytes; Humans; Hypertriglyceridemia; Insulin Resistance; Kupffer Cells; Liver Cirrhosis; Liver Transplantation; Metformin; Models, Biological; Non-alcoholic Fatty Liver Disease; Obesity; Oxidative Stress; Ursodeoxycholic Acid; Vitamin E | 2011 |
Systematic review with meta-analysis: non-alcoholic steatohepatitis - a case for personalised treatment based on pathogenic targets.
Topics: Bariatric Surgery; Fatty Liver; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lactones; Metabolic Syndrome; Metformin; Non-alcoholic Fatty Liver Disease; Orlistat; Precision Medicine; Thiazolidinediones; Ursodeoxycholic Acid; Vitamin E; Weight Loss | 2014 |
Current Pharmacologic Therapy for Nonalcoholic Fatty Liver Disease.
Topics: Angiotensin Receptor Antagonists; Anti-Inflammatory Agents, Non-Steroidal; Anti-Obesity Agents; Anticholesteremic Agents; Antioxidants; Cannabinoid Receptor Antagonists; Cholagogues and Choleretics; Fatty Acids, Omega-3; Glucagon-Like Peptide-1 Receptor; Humans; Hypoglycemic Agents; Insulin Resistance; Lactones; Metformin; Non-alcoholic Fatty Liver Disease; Orlistat; Pentoxifylline; Piperidines; Probiotics; Pyrazoles; Rimonabant; Synbiotics; Thiazolidinediones; Ursodeoxycholic Acid; Vitamin E | 2016 |
Non-alcoholic fatty liver disease and steatohepatitis: State of the art on effective therapeutics based on the gold standard method for diagnosis.
Topics: Biopsy; Disease Progression; Humans; Liver; Liver Cirrhosis; Metformin; Non-alcoholic Fatty Liver Disease; Pentoxifylline; Pioglitazone; Randomized Controlled Trials as Topic; Rosiglitazone; Severity of Illness Index; Treatment Outcome; Ursodeoxycholic Acid; Vitamin E | 2021 |
3 trial(s) available for metformin and ursodeoxycholic acid
| Article | Year |
|---|---|
Biliary effects of liraglutide and sitagliptin, a 12-week randomized placebo-controlled trial in type 2 diabetes patients.
Topics: Aged; Bile Acids and Salts; Blood Glucose; Chenodeoxycholic Acid; Cholic Acid; Deoxycholic Acid; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Double-Blind Method; Drug Therapy, Combination; Fasting; Feces; Female; Gallbladder; Glucagon-Like Peptide-1 Receptor; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Liraglutide; Male; Metformin; Middle Aged; Organ Size; Postprandial Period; Sitagliptin Phosphate; Sulfonylurea Compounds; Ultrasonography; Ursodeoxycholic Acid | 2016 |
N-ACETYLCYSTEINE AND/OR URSODEOXYCHOLIC ACID ASSOCIATED WITH METFORMIN IN NON-ALCOHOLIC STEATOHEPATITIS: AN OPEN-LABEL MULTICENTER RANDOMIZED CONTROLLED TRIAL.
Topics: Acetylcysteine; Adolescent; Adult; Aged; Drug Therapy, Combination; Female; Humans; Male; Metformin; Middle Aged; Non-alcoholic Fatty Liver Disease; Treatment Outcome; Ursodeoxycholic Acid; Young Adult | 2019 |
A multi-centered trial investigating gestational treatment with ursodeoxycholic acid compared to metformin to reduce effects of diabetes mellitus (GUARD): a randomized controlled trial protocol.
Topics: Blood Glucose; Diabetes Mellitus, Type 2; Diabetes, Gestational; Female; Glucose; Humans; Infant, Newborn; Metformin; Multicenter Studies as Topic; Pregnancy; Premature Birth; Randomized Controlled Trials as Topic; Ursodeoxycholic Acid | 2022 |
11 other study(ies) available for metformin and ursodeoxycholic acid
| Article | Year |
|---|---|
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Identification of small molecules that bind to the mitochondrial protein mitoNEET.
Topics: Hypoglycemic Agents; Ligands; Mitochondrial Proteins; Protein Binding; Small Molecule Libraries; Thiazolidinediones | 2016 |
[Fatty liver and raised gamma-GT: it can happen to abstainers, too].
Topics: Cholagogues and Choleretics; Clinical Enzyme Tests; Diabetes Complications; Diagnosis, Differential; Fatty Liver; Female; gamma-Glutamyltransferase; Humans; Hypoglycemic Agents; Male; Metformin; Obesity; Risk Factors; Ursodeoxycholic Acid; Vitamin E | 2002 |
Longer lifespan in male mice treated with a weakly estrogenic agonist, an antioxidant, an α-glucosidase inhibitor or a Nrf2-inducer.
Topics: Acarbose; alpha-Glucosidases; Animals; Antioxidants; Drugs, Chinese Herbal; Estradiol; Fish Oils; Glycoside Hydrolase Inhibitors; Hand Strength; Longevity; Male; Masoprocol; Metformin; Mice; NF-E2-Related Factor 2; Rotarod Performance Test; Sirolimus; Survival Analysis; Ursodeoxycholic Acid | 2016 |
Managing Recurring Obstetric Cholestasis With Metformin.
Topics: Adult; Bile Acids and Salts; Cholagogues and Choleretics; Cholestasis, Intrahepatic; Diabetes, Gestational; Drug Therapy, Combination; Female; Humans; Hypoglycemic Agents; Metformin; Pregnancy; Pregnancy Complications; Recurrence; Rifampin; Ursodeoxycholic Acid | 2016 |
Metformin treatment prevents gallstone formation but mimics porcelain gallbladder in C57Bl/6 mice.
Topics: Animals; Calcinosis; Cholagogues and Choleretics; Cholesterol; Diabetes Mellitus, Type 2; Diet, High-Fat; Disease Models, Animal; Gallbladder; Gallbladder Diseases; Gallstones; Humans; Hypoglycemic Agents; Male; Metabolic Syndrome; Metformin; Mice; Mice, Inbred C57BL; Ursodeoxycholic Acid | 2018 |
Gut microbiota and intestinal FXR mediate the clinical benefits of metformin.
Topics: Bacteroides; Bile Acids and Salts; Diabetes Mellitus, Type 2; Diet, High-Fat; Gastrointestinal Microbiome; Gene Expression Regulation, Bacterial; Glucose Intolerance; Humans; Hyperglycemia; Metabolome; Metagenomics; Metformin; Obesity; Receptors, Cytoplasmic and Nuclear; Ursodeoxycholic Acid | 2018 |