metformin and tretinoin

metformin has been researched along with tretinoin in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (15.38)29.6817
2010's8 (61.54)24.3611
2020's3 (23.08)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Elo, B; Govorko, D; Villano, CM; White, LA1
Chen, Y; Huai, L; Jia, Y; Li, Q; Li, Y; Rao, Q; Tian, Z; Wang, C; Wang, J; Wang, M; Xing, H; Zhang, C1
Ardah, MT; Dulovic, M; El-Agnaf, OM; Harhaji-Trajkovic, L; Jovanovic, M; Kostic, V; Kravic-Stevovic, T; Markovic, I; Paunovic, V; Stefanis, L; Trajkovic, V; Xilouri, M1
Chang, C; Fukunaga, T; Hamada, M; He, M; Shi, H; Sun, Y; Yang, X; Zhang, X1
Andanooru Chandrappa, NK; Banavase Channakeshavaiah, R1
Binlateh, T; Hutamekalin, P; Prommeenate, P; Reudhabibadh, R1

Reviews

1 review(s) available for metformin and tretinoin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for metformin and tretinoin

ArticleYear
Topical metformin in the treatment of melasma: A preliminary clinical trial.
    Journal of cosmetic dermatology, 2020, Volume: 19, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Drug Combinations; Female; Fluocinolone Acetonide; Humans; Hydroquinones; Male; Melanosis; Metformin; Middle Aged; Ointments; Patient Satisfaction; Prospective Studies; Severity of Illness Index; Skin Lightening Preparations; Skin Pigmentation; Treatment Outcome; Tretinoin; Young Adult

2020

Other Studies

11 other study(ies) available for metformin and tretinoin

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Larval zebrafish as a model for glucose metabolism: expression of phosphoenolpyruvate carboxykinase as a marker for exposure to anti-diabetic compounds.
    Journal of molecular endocrinology, 2007, Volume: 38, Issue:4

    Topics: Animals; Blood Glucose; Cyclic AMP; Dexamethasone; Glipizide; Hypoglycemic Agents; Larva; Metformin; Models, Animal; Phosphoenolpyruvate Carboxykinase (GTP); Rosiglitazone; Thiazolidinediones; Tretinoin; Zebrafish

2007
Metformin induces differentiation in acute promyelocytic leukemia by activating the MEK/ERK signaling pathway.
    Biochemical and biophysical research communications, 2012, Jun-08, Volume: 422, Issue:3

    Topics: Antineoplastic Agents; Apoptosis; Cell Differentiation; Cell Line, Tumor; Humans; Hypoglycemic Agents; Leukemia, Promyelocytic, Acute; MAP Kinase Signaling System; Metformin; Oncogene Proteins, Fusion; Tretinoin

2012
The protective role of AMP-activated protein kinase in alpha-synuclein neurotoxicity in vitro.
    Neurobiology of disease, 2014, Volume: 63

    Topics: alpha-Synuclein; Aminoimidazole Carboxamide; AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Animals; Cell Death; Cell Differentiation; Cells, Cultured; Cerebral Cortex; Culture Media, Conditioned; DNA Fragmentation; Embryo, Mammalian; Humans; Hypoglycemic Agents; Metformin; Neuroblastoma; Neurons; Protein Serine-Threonine Kinases; Rats; Ribonucleotides; RNA, Small Interfering; Tretinoin

2014
Targeting the TR4 nuclear receptor-mediated lncTASR/AXL signaling with tretinoin increases the sunitinib sensitivity to better suppress the RCC progression.
    Oncogene, 2020, Volume: 39, Issue:3

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Axl Receptor Tyrosine Kinase; Carcinoma, Renal Cell; Cell Hypoxia; Cell Line, Tumor; Cell Movement; Disease Progression; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; Kidney Neoplasms; Metformin; Mice; Proto-Oncogene Proteins; Receptor Protein-Tyrosine Kinases; Receptors, Steroid; Receptors, Thyroid Hormone; RNA, Long Noncoding; RNA, Small Interfering; Signal Transduction; Sunitinib; Tretinoin; Xenograft Model Antitumor Assays

2020
Investigation of mechanisms underlying the inhibitory effects of metformin against proliferation and growth of neuroblastoma SH-SY5Y cells.
    Toxicology in vitro : an international journal published in association with BIBRA, 2022, Volume: 83

    Topics: Cell Differentiation; Cell Line, Tumor; Humans; Metformin; Neuroblastoma; Tretinoin

2022