metformin has been researched along with thyroxine in 44 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (4.55) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (13.64) | 29.6817 |
| 2010's | 26 (59.09) | 24.3611 |
| 2020's | 10 (22.73) | 2.80 |
| Authors | Studies |
|---|---|
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Sapeika, N | 1 |
| Weinhaus, RS | 1 |
| Wiener, K | 1 |
| Fitzgerald, BP; Kennedy, EL; Murphy, BA; Reedy, SE; Sessions, DR; Vick, MM | 1 |
| Cordido, F; Isidro, ML; Nemiña, R; Penín, MA | 1 |
| Jatwa, R; Kar, A | 1 |
| Agabiti-Rosei, E; Agosti, B; Cappelli, C; Castellano, M; Chiovato, L; Cimino, A; De Martino, E; Gandossi, E; Pirola, I; Rotondi, M; Valentini, U | 1 |
| Niepomniszcze, H; Pitoia, F; Pusiol, E; Rezzónico, J; Rezzónico, M | 1 |
| Botta, R; Cappelli, C; Castellano, M; Chiovato, L; De Cata, P; Dionisio, R; Iacobello, C; Magri, F; Nappi, RE; Rotondi, M | 1 |
| Krysiak, R; Okopien, B | 1 |
| Díez, JJ; Iglesias, P | 2 |
| Agosti, B; Cappelli, C; Castellano, M; Chiovato, L; Formenti, A; Leporati, P; Pirola, I; Rotondi, M; Valentini, U; Zarra, E | 1 |
| Dasari, S; Naha, K; Prabhu, M; Vivek, G | 1 |
| Casteràs, A; Ciudin, A; Mesa, J; Zafon, C | 1 |
| Distiller, LA; Joffe, BI; Polakow, ES | 1 |
| Ambrosino, P; Di Minno, A; Di Minno, MN; Lupoli, GA; Lupoli, R; Tortora, A | 1 |
| Dourandish, L; Mousavi, Z; Rasoul Zakavi, S; Rokni, H; Sadeghi, R | 1 |
| Krysiak, R; Okopien, B; Szkrobka, W | 2 |
| He, LR; Ho, L; Hofstetter, WL; Komaki, R; Liao, ZX; Lin, SH; Qiao, W | 1 |
| Barreto, A; Blanc, E; Brenta, G; Brodschi, D; Cejas, C; Faingold, C; Fossati, P; Musso, C; Nepote, A; Ponce, C; Salgado, P; Schnitman, M | 1 |
| Al-Alusi, MA; Braverman, LE; Du, L; He, X; Leung, AM; Li, N; Yeh, MW | 1 |
| Gilowska, M; Krysiak, R; Okopień, B; Szkróbka, W | 1 |
| Floyd, L; Shariat-Madar, Z; Tabrizian, T | 1 |
| Ferreira, A; Lim, PH; Redei, EE; Tunc-Ozcan, E; Wert, SL | 1 |
| Bolboacă, SD; Ghervan, C; Mârza, S; Moga, D; Răcătăianu, N; Sitar-Tăut, AV; Valea, A | 1 |
| Janssen, MJR; Netea-Maier, RT; Peeters, RP; Sloot, YJE; Smit, JWA; van Herwaarden, AE | 1 |
| Durgia, H; Kamalanathan, S; Kar, SS; Palui, R; Patil, M; Raj, H; Sahoo, J; Sridharan, K | 1 |
| Di, Y; Fan, Q; Gao, J; Li, H; Wang, J | 1 |
| Cui, M; Gang, X; Jiang, Z; Li, Z; Wang, G; Xiao, X | 1 |
| Kowalcze, K; Krysiak, R; Okopień, B | 3 |
| Creagh, F; Goonoo, MS; Morris, R; Raithatha, A | 1 |
| Glick, A; Johnson, C; Sista, V | 1 |
| Ameen, AM; Amin, MK; El Sherif, I; Elaidy, SM; Elkholy, SE; Hassan, WA; Tawfik, MM | 1 |
| Antony, B; Blau, H; Bramante, C; Casiraghi, E; Chan, LE; Coleman, B; Gargano, M; Haendel, M; Harris, NL; Laraway, B; Reese, J; Robinson, PN; Sahner, D; Valentini, G; Wilkins, K; Zaman, A | 1 |
| Ben-David, U; Carmi-Levy, I; Farkash, O; Goldberg, A; Grinshpun, A; Keren, N; Khatib, M; Rubinek, T; Salmon-Divon, M; Shachar, SS; Sonnenblick, A; Waissengrin, B; Winkler, T; Wolf, I; Zahavi, T; Zubkov, A | 1 |
| Amirabadizadeh, A; Amouzegar, A; Azizi, F; Mehran, L | 1 |
5 review(s) available for metformin and thyroxine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
The management of obesity: some recent concepts.
Topics: Adaptation, Psychological; Adipose Tissue; Appetite Depressants; Attitude; Chlorphentermine; Defense Mechanisms; Diet Therapy; Diet, Reducing; Diethylpropion; Exercise Therapy; Humans; Metformin; Nervous System; Obesity; Phenformin; Thyroid Hormones; Thyroxine; Triiodothyronine | 1969 |
Effects of treatment with metformin on TSH levels: a meta-analysis of literature studies.
Topics: Hormone Replacement Therapy; Humans; Hypoglycemic Agents; Hypothyroidism; Metformin; Thyrotropin; Thyroxine | 2014 |
The Effect of Metformin on Thyroid-Associated Serum Hormone Levels and Physiological Indexes: A Meta-Analysis.
Topics: Blood Pressure; Humans; Metformin; Thyrotropin; Thyroxine; Triiodothyronine | 2019 |
The effect of metformin therapy on serum thyrotropin and free thyroxine concentrations in patients with type 2 diabetes: a meta-analysis.
Topics: Adolescent; Adult; Diabetes Mellitus, Type 2; Humans; Hypothyroidism; Metformin; Thyroid Hormones; Thyrotropin; Thyroxine; Triiodothyronine | 2023 |
7 trial(s) available for metformin and thyroxine
| Article | Year |
|---|---|
Metformin reduces thyrotropin levels in obese, diabetic women with primary hypothyroidism on thyroxine replacement therapy.
Topics: Aged; Body Weight; Diabetes Mellitus, Type 2; Female; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Hypothyroidism; Metformin; Middle Aged; Obesity; Prospective Studies; Thyrotropin; Thyroxine; Triiodothyronine | 2007 |
TSH-lowering effect of metformin in type 2 diabetic patients: differences between euthyroid, untreated hypothyroid, and euthyroid on L-T4 therapy patients.
Topics: Diabetes Mellitus, Type 2; Humans; Hypoglycemic Agents; Hypothyroidism; Metformin; Thyroid Diseases; Thyrotropin; Thyroxine; Time | 2009 |
Metformin treatment for small benign thyroid nodules in patients with insulin resistance.
Topics: Adult; Aged; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Hypoglycemic Agents; Insulin Resistance; Metformin; Middle Aged; Thyroid Nodule; Thyroxine; Tumor Burden; Young Adult | 2011 |
Thyroidal effect of metformin treatment in patients with polycystic ovary syndrome.
Topics: Adult; Female; Humans; Hypoglycemic Agents; Hypothyroidism; Metformin; Polycystic Ovary Syndrome; Thyroid Gland; Thyroid Hormones; Thyrotropin; Thyroxine; Time Factors; Treatment Outcome; Triiodothyronine; Young Adult | 2011 |
Effects of short-term metformin therapy associated with levothyroxine dose decrement on TSH and thyroid hormone levels in patients with thyroid cancer.
Topics: Adenocarcinoma, Follicular; Adult; Body Weight; Carcinoma, Papillary; Dose-Response Relationship, Drug; Female; Heart Rate; Humans; Hyperthyroidism; Male; Metformin; Middle Aged; Single-Blind Method; Thyroid Hormones; Thyroid Neoplasms; Thyrotropin; Thyroxine; Treatment Failure; Young Adult | 2014 |
The Influence of Energy Depletion by Metformin or Hypocaloric Diet on Thyroid Iodine Uptake in Healthy Volunteers: a Randomized Trial.
Topics: Adult; Biological Transport; Diet, Reducing; Energy Metabolism; Healthy Volunteers; Humans; Hypoglycemic Agents; Iodine Radioisotopes; Male; Metformin; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine; Young Adult | 2019 |
Effect of metformin on thyroid function tests in patients with subclinical hypothyroidism: an open-label randomised controlled trial.
Topics: Adiponectin; Adult; Blood Glucose; Cholesterol; Female; Humans; Hypothyroidism; Insulin Resistance; Leptin; Male; Metformin; Middle Aged; Prolactin; Thyroid Function Tests; Thyrotropin; Thyroxine; Triiodothyronine | 2019 |
32 other study(ies) available for metformin and thyroxine
| Article | Year |
|---|---|
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Drugs in obesity.
Topics: Amphetamine; Appetite Depressants; Diet, Reducing; Diuretics; Ephedrine; Fenfluramine; Health Education; Humans; Legislation, Drug; Metformin; Methylcellulose; Motivation; Obesity; Phenformin; Physical Exertion; South Africa; Thyroxine | 1974 |
A falling HbA1c is not necessarily an indicator of improving diabetes control.
Topics: Biomarkers; Diabetes Mellitus, Type 2; Female; Flupenthixol; Glycated Hemoglobin; Hemoglobins; Hemolysis; Humans; Hypoglycemic Agents; Hypothyroidism; Metformin; Middle Aged; Panic Disorder; Prednisolone; Reproducibility of Results; Thyroxine; Time Factors; Tranquilizing Agents | 2001 |
Obesity is associated with altered metabolic and reproductive activity in the mare: effects of metformin on insulin sensitivity and reproductive cyclicity.
Topics: Animals; Breeding; Dose-Response Relationship, Drug; Estrous Cycle; Female; Food Deprivation; Horse Diseases; Horses; Hypoglycemic Agents; Insulin; Insulin Resistance; Leptin; Metformin; Obesity; Reproduction; Seasons; Thyroxine | 2006 |
Amelioration of metformin-induced hypothyroidism by Withania somnifera and Bauhinia purpurea extracts in Type 2 diabetic mice.
Topics: Animals; Bauhinia; Dexamethasone; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Female; Hypothyroidism; Metformin; Mice; Plant Bark; Plant Extracts; Plant Roots; Thyroxine; Triiodothyronine; Withania | 2009 |
Thyrotropin-lowering effect of metformin in a patient with resistance to thyroid hormone.
Topics: Adult; Diabetes Mellitus, Type 2; Humans; Hypothyroidism; Male; Metformin; Thyroid Hormone Resistance Syndrome; Thyrotropin; Thyroxine | 2011 |
An analysis of the relative risk for hypothyroidism in patients with Type 2 diabetes.
Topics: Aged; Autoantibodies; Diabetes Mellitus, Type 2; Fasting; Female; Humans; Hypoglycemic Agents; Hypothyroidism; Logistic Models; Male; Metformin; Odds Ratio; Prevalence; Risk; Thyrotropin; Thyroxine | 2012 |
Thyreotropin levels in diabetic patients on metformin treatment.
Topics: Adult; Aged; Autoantibodies; Diabetes Complications; Diabetes Mellitus; Female; Humans; Hypoglycemic Agents; Hypothyroidism; Male; Metformin; Middle Aged; Polypharmacy; Retrospective Studies; Thyrotropin; Thyroxine; Triiodothyronine | 2012 |
Ketosis-prone type 2 diabetes mellitus in a patient with Sheehan's syndrome: a rare convergence of two distinct endocrine entities.
Topics: Adult; Diabetes Mellitus, Type 1; Drug Therapy, Combination; Female; Glucocorticoids; Humans; Hypoglycemia; Hypoglycemic Agents; Hypopituitarism; Insulin; Metformin; Thyroxine | 2012 |
Relationship between serum thyrotropin concentrations and metformin therapy in euthyroid patients with type 2 diabetes.
Topics: Aged; Case-Control Studies; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Goiter; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Osmolar Concentration; Retrospective Studies; Thyrotropin; Thyroxine; Triiodothyronine | 2013 |
Are levothyroxine requirements lower in thyroidectomized diabetic patients on metformin treatment?
Topics: Adult; Aged; Diabetes Mellitus, Type 2; Female; Hormone Replacement Therapy; Humans; Hypothyroidism; Male; Metformin; Middle Aged; Thyroidectomy; Thyroxine; Treatment Outcome | 2013 |
Type 2 diabetes mellitus and hypothyroidism: the possible influence of metformin therapy.
Topics: Adult; Aged; Aged, 80 and over; Cohort Studies; Diabetes Mellitus, Type 2; Ethnicity; Female; Hormone Replacement Therapy; Humans; Hypoglycemic Agents; Hypothyroidism; Male; Metformin; Middle Aged; Prevalence; Thyroxine | 2014 |
The effect of metformin on the hypothalamic-pituitary-thyroid axis in patients with type 2 diabetes and subclinical hyperthyroidism.
Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus, Type 2; Female; Humans; Hyperthyroidism; Hypoglycemic Agents; Hypothalamo-Hypophyseal System; Insulin Resistance; Male; Metformin; Middle Aged; Thyroid Function Tests; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine; Young Adult | 2015 |
Impact of comorbidities and use of common medications on cancer and non-cancer specific survival in esophageal carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Angiotensin Receptor Antagonists; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Asthma; Atrial Fibrillation; Chemoradiotherapy; Comorbidity; Diabetes Mellitus; Esophageal Neoplasms; Esophagectomy; Female; Humans; Hypertension; Hypothyroidism; Male; Metformin; Middle Aged; Pulmonary Disease, Chronic Obstructive; Retrospective Studies; Survival Rate; Thyroxine; Young Adult | 2015 |
Association between worse metabolic control and increased thyroid volume and nodular disease in elderly adults with metabolic syndrome.
Topics: Aged; Aged, 80 and over; Anthropometry; Argentina; Body Mass Index; Cohort Studies; Cross-Sectional Studies; Diabetes Complications; Diabetes Mellitus, Type 2; Female; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Male; Metabolic Syndrome; Metformin; Prospective Studies; Thyroid Diseases; Thyroid Gland; Thyroid Nodule; Thyrotropin; Thyroxine; Ultrasonography | 2015 |
Metformin Does Not Suppress Serum Thyrotropin by Increasing Levothyroxine Absorption.
Topics: Adult; Drug Interactions; Female; Humans; Hypoglycemic Agents; Male; Metformin; Thyrotropin; Thyroxine; Young Adult | 2015 |
The effect of metformin on the hypothalamic-pituitary-thyroid axis in patients with type 2 diabetes and amiodarone-induced hypothyroidism.
Topics: Aged; Amiodarone; Diabetes Mellitus, Type 2; Female; Humans; Hypothalamo-Hypophyseal System; Hypothyroidism; Insulin; Insulin Resistance; Insulin-Like Growth Factor I; Male; Metformin; Middle Aged; Prolactin; Thyroid Gland; Thyrotropin; Thyrotropin-Releasing Hormone; Thyroxine | 2016 |
Sex-dependent effect of metformin on hypothalamic-pituitary-thyroid axis activity in patients with subclinical hypothyroidism.
Topics: Adult; Aged; Female; Humans; Hypoglycemic Agents; Hypothalamo-Hypophyseal System; Hypothyroidism; Male; Metformin; Middle Aged; Pituitary-Adrenal System; Sex Characteristics; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine | 2016 |
Altered Prolylcarboxypeptidase Expression and Function in Response to Different Risk Factors of Diabetes.
Topics: Animals; Carboxypeptidases; Cardiovascular Diseases; Cell Survival; Cells, Cultured; Diabetes Mellitus, Type 2; Fatty Acids; Gene Expression Regulation, Enzymologic; Glucose; Insulin; Metformin; Myoblasts; Rats; Risk Factors; Thyroxine; Time Factors | 2017 |
Hippocampus-dependent memory and allele-specific gene expression in adult offspring of alcohol-consuming dams after neonatal treatment with thyroxin or metformin.
Topics: Alcohol Drinking; Alleles; Animals; Ethanol; Fear; Female; Fetal Alcohol Spectrum Disorders; Hippocampus; Male; Memory; Memory Disorders; Metformin; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Thyroxine; Transcriptome | 2018 |
The effect of Metformin treatment in obese insulin-resistant patients with euthyroid goiter.
Topics: Adolescent; Adult; Aged; Female; Goiter, Nodular; Humans; Hypoglycemic Agents; Insulin Resistance; Male; Metformin; Middle Aged; Obesity; Prospective Studies; Thyroxine; Young Adult | 2018 |
A cross-sectional study: Associations between sarcopenia and clinical characteristics of patients with type 2 diabetes.
Topics: Age Factors; Aged; Aged, 80 and over; Body Composition; Body Mass Index; China; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Exercise; Female; Humans; Logistic Models; Male; Metformin; Muscle, Skeletal; Risk Factors; Sarcopenia; Sex Factors; Thyroxine | 2020 |
Different effects of metformin on hypothalamic-pituitary-thyroid axis activity in levothyroxine-treated and levothyroxine-naïve women with non-autoimmune hypothyroidism.
Topics: Aged; Blood Glucose; Case-Control Studies; Female; Humans; Hypoglycemic Agents; Hypothalamo-Hypophyseal System; Hypothyroidism; Insulin Resistance; Metformin; Middle Aged; Thyroid Hormones; Thyrotropin; Thyroxine | 2020 |
Metformin-associated lactic acidosis: reinforcing learning points.
Topics: Acidosis, Lactic; Acute Kidney Injury; Bicarbonates; Continuous Renal Replacement Therapy; Diabetes Mellitus, Type 2; Drug Overdose; Glomerular Filtration Rate; Humans; Hypoglycemic Agents; Hypothyroidism; Lactic Acid; Male; Metformin; Renal Dialysis; Thyroxine; Young Adult | 2020 |
Oral Manifestations of Commonly Prescribed Drugs.
Topics: Albuterol; Amlodipine; Anticonvulsants; Antihypertensive Agents; Atorvastatin; Bisphosphonate-Associated Osteonecrosis of the Jaw; Bronchodilator Agents; Deprescriptions; Drug Hypersensitivity; Fluorides; Gingival Overgrowth; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperpigmentation; Hypoglycemic Agents; Lisinopril; Losartan; Metformin; Metoprolol; Mouth Diseases; Omeprazole; Oral Hygiene; Proton Pump Inhibitors; Simvastatin; Thyroxine; Toothpastes; Xerostomia | 2020 |
Differences in levothyroxine action on thyroid autoimmunity and hypothalamic-pituitary-thyroid axis activity between metformin- and myo-inositol-treated women with autoimmune subclinical hypothyroidism.
Topics: Autoimmunity; C-Reactive Protein; Female; Glucose; Hashimoto Disease; Humans; Hypothyroidism; Inositol; Insulin; Insulin Resistance; Iodide Peroxidase; Metformin; Prolactin; Thyroglobulin; Thyroid Hormones; Thyroiditis, Autoimmune; Thyrotropin; Thyroxine | 2022 |
Thyroid Antibody Titers and Hypothalamic-Pituitary-Thyroid Axis Activity in Levothyroxine-Treated Women With Autoimmune Subclinical Hypothyroidism Receiving Atorvastatin or Metformin.
Topics: Atorvastatin; C-Reactive Protein; Female; Hashimoto Disease; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypothyroidism; Inflammation; Insulin Resistance; Metformin; Thyroid Hormones; Thyrotropin; Thyroxine | 2022 |
Metformin alleviates the dysregulated testicular steroidogenesis and spermatogenesis induced by carbimazole in levothyroxine-primed rats.
Topics: Animals; bcl-2-Associated X Protein; Carbimazole; Caspase 3; Gonadal Steroid Hormones; Gonadotropins; Male; Metformin; NF-kappa B; Oxidative Stress; Proliferating Cell Nuclear Antigen; Rats; Rats, Wistar; Semen; Spermatogenesis; Testis; Testosterone; Thyroxine; Tumor Necrosis Factors | 2022 |
Metformin is associated with reduced COVID-19 severity in patients with prediabetes.
Topics: COVID-19; Female; Humans; Hypoglycemic Agents; Metformin; Polycystic Ovary Syndrome; Prediabetic State; Retrospective Studies; Thyroxine | 2022 |
The effect of non-oncology drugs on clinical and genomic risk in early luminal breast cancer.
Topics: Breast Neoplasms; Female; Genomics; Humans; Metformin; Neoplasm Recurrence, Local; Thyroxine | 2022 |