metformin has been researched along with thiamine in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (6.67) | 29.6817 |
| 2010's | 11 (73.33) | 24.3611 |
| 2020's | 3 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Chen, EC; Chien, HC; Giacomini, KM; Huang, Y; Khuri, N; Liang, X; Sali, A; Stecula, A; Yee, SW | 1 |
| Alston, TA | 1 |
| Ashrafi, K; Chen, EC; Chen, L; Chien, HC; Giacomini, KM; Keshari, KR; Kurhanewicz, J; Li, S; Liang, X; Lin, MJ; Liu, J; Morrissey, KM; Ostrem, J; Shokat, KM; Shu, Y; Xu, L; Yee, SW; Younger, NS; Zhang, Y; Zur, AA | 1 |
| Chen, L; Giacomini, KM; Yee, SW | 1 |
| Chen, EC; Chien, HC; Giacomini, KM; Giacomini, MM; Hao, J; Lepist, EI; Liang, X; Piao, M; Ray, AS; Twelves, J; Yee, SW | 1 |
| Fukuhara, A; Ishiguro, N; Kusuhara, H; Lechner, C; Nishiyama, K; Ohtsu, N; Shimizu, H; Takatani, M; Washio, I; Yamamura, N | 1 |
| Bynevelt, M; Franconi, C; McGarvey, C; Prentice, D | 1 |
| Aleshin, VA; Bunik, VI; Mkrtchyan, GV | 1 |
| Brockmöller, J; Gaedcke, J; Meyer, MJ; Oswald, S; Römer, S; Seitz, T; Tuerkova, A; Tzvetkov, MV; Wenzel, C; Zdrazil, B | 1 |
| Hatakeyama, M; Inoue, K; Kishimoto, H; Kurokawa, Y; Seki, M; Shirasaka, Y; Takemura, M; Tamai, I; Uchiyama, H; Wang, J; Yasugi, Y | 1 |
| Jimura, F; Kachi, N; Tamaki, H; Tsushima, H | 1 |
2 review(s) available for metformin and thiamine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Mechanisms of Non-coenzyme Action of Thiamine: Protein Targets and Medical Significance.
Topics: Animals; Brain; Coenzymes; Humans; Hypoglycemic Agents; Metformin; Mice; Phosphorylation; Protein Transport; Rats; Thiamine; Thiamine Deficiency; Thiamine Pyrophosphate; Vitamin B Complex | 2019 |
13 other study(ies) available for metformin and thiamine
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Discovery of Competitive and Noncompetitive Ligands of the Organic Cation Transporter 1 (OCT1; SLC22A1).
Topics: Drug Discovery; HEK293 Cells; Humans; Ligands; Molecular Docking Simulation; Organic Cation Transporter 1; Small Molecule Libraries | 2017 |
Does metformin interfere with thiamine?
Topics: Drug Interactions; Humans; Hypoglycemic Agents; Metformin; Thiamine; Thiamine Deficiency; Vitamin B 12 Deficiency | 2003 |
OCT1 is a high-capacity thiamine transporter that regulates hepatic steatosis and is a target of metformin.
Topics: AMP-Activated Protein Kinases; Animals; Carrier Proteins; Fatty Liver; Hypoglycemic Agents; Metformin; Mice; Mice, Knockout; Octamer Transcription Factor-1; Oxidation-Reduction; Thiamine | 2014 |
OCT1 in hepatic steatosis and thiamine disposition.
Topics: Animals; Energy Metabolism; Fatty Liver; Humans; Metformin; Mice; Models, Biological; Organic Cation Transporter 1; Thiamine | 2015 |
Metformin Is a Substrate and Inhibitor of the Human Thiamine Transporter, THTR-2 (SLC19A3).
Topics: Animals; Biological Transport; Cell Line; Drug Interactions; HEK293 Cells; Humans; Intestinal Absorption; Intestine, Small; Membrane Transport Proteins; Metformin; Mice; Substrate Specificity; Thiamine | 2015 |
Impact of Experimental Conditions on the Evaluation of Interactions between Multidrug and Toxin Extrusion Proteins and Candidate Drugs.
Topics: 1-Methyl-4-phenylpyridinium; Biological Transport; Buffers; Dose-Response Relationship, Drug; Drug Interactions; Estrone; HEK293 Cells; Humans; Hydrogen-Ion Concentration; Kinetics; Membrane Transport Modulators; Metformin; Organic Cation Transport Proteins; Rhodamine 123; Risk Assessment; Thiamine; Transfection | 2016 |
Metformin-induced encephalopathy: the role of thiamine.
Topics: Adult; Brain Diseases; Diabetic Nephropathies; Female; Humans; Hypoglycemic Agents; Metformin; Thiamine; Vitamin B Complex | 2018 |
Differences in Metformin and Thiamine Uptake between Human and Mouse Organic Cation Transporter 1: Structural Determinants and Potential Consequences for Intrahepatic Concentrations.
Topics: Animals; Drug Evaluation, Preclinical; HEK293 Cells; Hepatocytes; Humans; Liver; Male; Metformin; Mice; Organic Cation Transporter 1; Protein Conformation, alpha-Helical; Rats; Recombinant Fusion Proteins; Recombinant Proteins; Sequence Homology, Amino Acid; Species Specificity; Structure-Activity Relationship; Thiamine | 2020 |
Multiple Transport Mechanisms Involved in the Intestinal Absorption of Metformin: Impact on the Nonlinear Absorption Kinetics.
Topics: Animals; Biological Transport; Caco-2 Cells; Humans; Intestinal Absorption; Kinetics; Membrane Transport Proteins; Metformin; Rats; Thiamine | 2022 |
Cardiac Dysfunction Due to Thiamine Deficiency after Hemodialysis for Biguanide-related Lactic Acidosis.
Topics: Acidosis, Lactic; Beriberi; Biguanides; Diabetes Mellitus, Type 2; Heart Diseases; Humans; Hypoglycemic Agents; Metformin; Renal Dialysis; Thiamine; Thiamine Deficiency | 2022 |