metformin and theophylline

metformin has been researched along with theophylline in 24 studies

Research

Studies (24)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (4.17)	18.7374
1990's	2 (8.33)	18.2507
2000's	8 (33.33)	29.6817
2010's	12 (50.00)	24.3611
2020's	1 (4.17)	2.80

Authors

Authors	Studies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Lombardo, F; Obach, RS; Waters, NJ	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Campillo, NE; Guerra, A; Páez, JA	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Nolan, DB	1
Quasny, H	1
UESUGI, Y	1
Bittinger, F; Herschel, S; Kirkpatrick, CJ; Wessler, I	1
De Vriese, AS; Van Praet, JT	1
Davidson, SM; Gonçalves, L; Hausenloy, DJ; Mocanu, MM; Monteiro, P; Paiva, M; Providência, L; Riksen, NP; Rongen, GA; Smits, P; Yellon, DM	1
Li, L; Mao, S; Ni, R; Shao, Y; Wang, L; Zhang, T	1
Fatima, Z; Kaur, CD; Srivastava, D	1
Harazim, M; Horák, J; Matějovič, M; Raděj, J	1
Conway, BR; Ghori, MU; Khizer, Z; Nirwan, JS	1

Reviews

4 review(s) available for metformin and theophylline

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Prevention of contrast-induced nephropathy: a critical review. Current opinion in nephrology and hypertension, 2007, Volume: 16, Issue:4 Topics: Acetylcysteine; Acute Kidney Injury; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Contrast Media; Creatinine; Diuretics; Evidence-Based Medicine; Fluid Therapy; Humans; Mannitol; Metformin; Osmolar Concentration; Randomized Controlled Trials as Topic; Renal Replacement Therapy; Risk Factors; Theophylline; Viscosity	2007
Multicomponent Pharmaceutical Cocrystals: A Novel Approach for Combination Therapy. Mini reviews in medicinal chemistry, 2018, Volume: 18, Issue:14 Topics: Asthma; Chemistry, Pharmaceutical; Crystallization; Diabetes Mellitus; Drug Therapy, Combination; Flufenamic Acid; Gliclazide; Humans; Metformin; Pharmaceutical Preparations; Theophylline	2018
Extracorporeal removal techniques in toxicology: part 2. Vnitrni lekarstvi, 2019,Summer, Volume: 65, Issue:6 Topics: Acidosis, Lactic; Drug Overdose; Humans; Hypoglycemic Agents; Metformin; Renal Dialysis; Theophylline	2019

Other Studies

20 other study(ies) available for metformin and theophylline

Article	Year
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data. European journal of medicinal chemistry, 2009, Volume: 44, Issue:11 Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors. European journal of medicinal chemistry, 2010, Volume: 45, Issue:3 Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Theophylline option for attenuating contrast media-induced nephrotoxicity in patients on metformin. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 1997, Mar-01, Volume: 54, Issue:5 Topics: Acidosis, Lactic; Contraindications; Contrast Media; Diabetes Mellitus, Type 2; Humans; Hypoglycemic Agents; Kidney Diseases; Metformin; Theophylline	1997
Metformin, contrast media, and theophylline. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 1997, Sep-01, Volume: 54, Issue:17 Topics: Acidosis, Lactic; Contraindications; Contrast Media; Diabetes Mellitus, Type 2; Humans; Hypoglycemic Agents; Kidney Diseases; Metformin; Phosphodiesterase Inhibitors; Theophylline	1997
[EFFECTS OF VARIOUS NATURAL ORGANIC SUBSTANCES AND AMINO ACIDS ON THE BLOOD SURGAR LEVEL AND EXPERIMENTAL STUDIES ON ORAL HYPOGLYCEMIC AGENTS]. Nihon Naibunpi Gakkai zasshi, 1963, Nov-20, Volume: 39 Topics: Amino Acids; Animals; Bile Acids and Salts; Blood Chemical Analysis; Blood Glucose; Caffeine; Chlorpropamide; Creatine; Creatinine; Cystine; Diabetes Mellitus, Experimental; Hippurates; Hypoglycemic Agents; Injections; Injections, Intravenous; Metformin; Pathology; Pharmacology; Rats; Research; Salts; Theobromine; Theophylline; Tyrosine	1963
Release of non-neuronal acetylcholine from the isolated human placenta is affected by antidepressants. Life sciences, 2007, May-30, Volume: 80, Issue:24-25 Topics: Acetylcholine; Amitriptyline; Antidepressive Agents; Dose-Response Relationship, Drug; Doxepin; Female; Humans; Hypoglycemic Agents; In Vitro Techniques; Metformin; Minoxidil; Neurons; Placenta; Pregnancy; Theophylline; Time Factors; Vasodilator Agents	2007
Metformin prevents myocardial reperfusion injury by activating the adenosine receptor. Journal of cardiovascular pharmacology, 2009, Volume: 53, Issue:5 Topics: Adenosine; Animals; Biological Transport; Hypoglycemic Agents; In Vitro Techniques; Male; Metformin; Myocardial Infarction; Myocardial Reperfusion Injury; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Theophylline; Thioinosine	2009
Drug release characteristics from chitosan-alginate matrix tablets based on the theory of self-assembled film. International journal of pharmaceutics, 2013, Jun-25, Volume: 450, Issue:1-2 Topics: Acetaminophen; Alginates; Cellulose; Chitosan; Glucuronic Acid; Hexuronic Acids; Hydrogen-Ion Concentration; Metformin; Osmolar Concentration; Stearic Acids; Tablets; Theophylline; Trimetazidine	2013
Okra (Hibiscus esculentus) gum based hydrophilic matrices for controlled drug delivery applications: Estimation of percolation threshold. International journal of biological macromolecules, 2020, Jul-15, Volume: 155 Topics: Abelmoschus; Drug Carriers; Drug Compounding; Drug Liberation; Flurbiprofen; Hydrophobic and Hydrophilic Interactions; Kinetics; Metformin; Plant Gums; Porosity; Solubility; Theophylline	2020