metformin has been researched along with tacrolimus in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (13.33) | 29.6817 |
| 2010's | 11 (73.33) | 24.3611 |
| 2020's | 2 (13.33) | 2.80 |
| Authors | Studies |
|---|---|
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Bennett, RG; Clure, CC; Hamel, FG; Larsen, JL; Shivaswamy, V | 1 |
| Arnon, R; Goldis, M; Regelmann, MO | 1 |
| Chung, BH; Jin, J; Jin, L; Kim, HS; Lim, SW; Yang, CW; Yu, JH | 1 |
| Albaghdadi, AJ; Hewitt, MA; Kan, FW; Ozolinš, TR; Putos, SM; Wells, M | 1 |
| Avvari, S; Gollen, R; Jogiraju, VK; Taft, DR | 1 |
| Albaghdadi, AJH; Kan, FWK | 1 |
| Ahn, SW; Hong, SK; Kim, H; Kim, HS; Lee, KW; Mussin, N; Oh, DK; Oh, SC; Park, MY; Seo, S; Suh, KS; Yi, NJ; Yoon, KC | 1 |
| Allard, J; Angeli, M; Baciu, C; Bhat, M; Das, A; Humar, A; Pasini, E; Watt, KD | 1 |
| Bae, SH; Beak, JA; Cho, ML; Choi, HJ; Choi, JW; Choi, JY; Jang, JW; Jhun, JY; Lee, SK; Park, MJ; Rye, JY; Yoon, SK; You, YK | 1 |
2 review(s) available for metformin and tacrolimus
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
New-onset diabetes mellitus after pediatric liver transplantation.
Topics: Albuminuria; Child; Cyclosporine; Diabetes Mellitus; Diabetic Retinopathy; Glucocorticoids; Humans; Hyperlipidemias; Hypertension; Immunosuppressive Agents; Insulin; Liver Failure; Liver Transplantation; Metformin; Pediatrics; Risk Factors; Sirolimus; Tacrolimus | 2015 |
13 other study(ies) available for metformin and tacrolimus
| Article | Year |
|---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Metformin improves immunosuppressant induced hyperglycemia and exocrine apoptosis in rats.
Topics: Animals; Apoptosis; Biomarkers; Blood Glucose; Disease Models, Animal; Glucose Tolerance Test; Hyperglycemia; Hyperinsulinism; Hypoglycemic Agents; Immunohistochemistry; Immunosuppressive Agents; In Situ Nick-End Labeling; Insulin; Male; Metformin; Pancreas, Exocrine; Rats; Rats, Sprague-Dawley; Sirolimus; Tacrolimus; Time Factors | 2013 |
Effects of metformin on hyperglycemia in an experimental model of tacrolimus- and sirolimus-induced diabetic rats.
Topics: Animals; Diabetes Mellitus, Experimental; Humans; Hypoglycemic Agents; Immunosuppressive Agents; Islets of Langerhans; Kidney Transplantation; Metformin; Rats; Rats, Sprague-Dawley; Sirolimus; Tacrolimus | 2017 |
Tacrolimus in the prevention of adverse pregnancy outcomes and diabetes-associated embryopathies in obese and diabetic mice.
Topics: Animals; Bone and Bones; Diabetes Mellitus, Experimental; Diet, High-Fat; Female; Fetal Diseases; Glucose Tolerance Test; Metformin; Mice, Inbred BALB C; Mice, Obese; Pregnancy; Pregnancy Outcome; Spine; Tacrolimus; Umbilical Cord; Uterine Artery; Vascular Remodeling | 2017 |
Application of physiologically based pharmacokinetic modeling to predict drug disposition in pregnant populations.
Topics: Adult; Computer Simulation; Female; Humans; Metformin; Middle Aged; Models, Biological; Oseltamivir; Pregnancy; Reproducibility of Results; Tacrolimus; Young Adult | 2017 |
Immunosuppression with tacrolimus improved implantation and rescued expression of uterine progesterone receptor and its co-regulators FKBP52 and PIASy at nidation in the obese and diabetic mice: Comparative studies with metformin.
Topics: Animals; Diabetes Mellitus, Experimental; Diet, High-Fat; Embryo Implantation; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Immunosuppression Therapy; Interferon-gamma; Interleukin-11; Leukemia Inhibitory Factor; Metformin; Mice; Mice, Obese; NF-kappa B; Phenotype; Phosphorylation; Protein Inhibitors of Activated STAT; Receptors, Progesterone; STAT3 Transcription Factor; Tacrolimus; Tacrolimus Binding Proteins; Uterus | 2018 |
Sirolimus and Metformin Synergistically Inhibits Colon Cancer In Vitro and In Vivo.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Colonic Neoplasms; Cyclosporine; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; HCT116 Cells; HT29 Cells; Humans; Metformin; Mice; Mice, Inbred BALB C; Mice, Nude; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Sirolimus; Smad3 Protein; Tacrolimus; Transplantation, Heterologous | 2017 |
Diabetogenic Effects of Immunosuppression: An Integrative Analysis.
Topics: Datasets as Topic; Diabetes Mellitus, Type 2; Down-Regulation; Gene Expression Profiling; Graft Rejection; Hep G2 Cells; Humans; Hypoglycemic Agents; Immunosuppressive Agents; Insulin; Metformin; Organ Transplantation; Signal Transduction; Tacrolimus; THP-1 Cells; Up-Regulation | 2020 |
Combination Treatment With Metformin and Tacrolimus Improves Systemic Immune Cellular Homeostasis by Modulating Treg and Th17 Imbalance.
Topics: Adolescent; Animals; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Proliferation; Cells, Cultured; Drug Therapy, Combination; Female; Graft vs Host Disease; Homeostasis; Humans; Leukocytes, Mononuclear; Lymphocyte Activation; Male; Metformin; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; T-Lymphocytes, Regulatory; Tacrolimus; Th17 Cells | 2020 |