Compounds > metformin

metformin and su 11248

metformin has been researched along with su 11248 in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (10.00)29.6817
2010's7 (70.00)24.3611
2020's2 (20.00)2.80

Authors

AuthorsStudies
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Chen, EC; Chien, HC; Giacomini, KM; Huang, Y; Khuri, N; Liang, X; Sali, A; Stecula, A; Yee, SW1
Hasinoff, BB; O'Hara, KA; Patel, D1
Alcocer-Gómez, E; Apetoh, L; Battino, M; Bullón, P; Carrión, AM; Cordero, MD; Culic, O; Garrido-Maraver, J; Ghiringhelli, F; Marín-Aguilar, F; Román-Malo, L; Ruiz-Cabello, J; Ryffel, B; Sánchez-Alcazar, JA1
Berger, R; Carducci, MA; Eisenberger, MA; Gottfried, M; Hammers, H; Ish-Shalom, M; Keizman, D; Maimon, N; Mermershtain, W; Neiman, V; Peer, A; Rosenbaum, E; Rouvinov, K; Sarid, D; Sella, A; Sinibaldi, V1
Choueiri, TK; Hamieh, L; Lin, X; McKay, RR; Moreira, RB; Simantov, R1
Chang, C; Fukunaga, T; Hamada, M; He, M; Shi, H; Sun, Y; Yang, X; Zhang, X1
Gharanei, M; Haussmann, I; Kuburas, R; Maddock, H; Sandhu, H1

Reviews

1 review(s) available for metformin and su 11248

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

9 other study(ies) available for metformin and su 11248

ArticleYear
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Identification of potent Yes1 kinase inhibitors using a library screening approach.
    Bioorganic & medicinal chemistry letters, 2013, Aug-01, Volume: 23, Issue:15

    Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship

2013
Discovery of Competitive and Noncompetitive Ligands of the Organic Cation Transporter 1 (OCT1; SLC22A1).
    Journal of medicinal chemistry, 2017, 04-13, Volume: 60, Issue:7

    Topics: Drug Discovery; HEK293 Cells; Humans; Ligands; Molecular Docking Simulation; Organic Cation Transporter 1; Small Molecule Libraries

2017
Mechanisms of myocyte cytotoxicity induced by the multiple receptor tyrosine kinase inhibitor sunitinib.
    Molecular pharmacology, 2008, Volume: 74, Issue:6

    Topics: Acetyl-CoA Carboxylase; Adenosine Triphosphate; AMP-Activated Protein Kinases; Animals; Animals, Newborn; Antineoplastic Agents; Apoptosis; Cells, Cultured; Hypoglycemic Agents; Indoles; L-Lactate Dehydrogenase; Metformin; Muscle Cells; Oxidative Stress; Phenformin; Phosphorylation; Pyrroles; Rats; Rats, Sprague-Dawley; Receptor Protein-Tyrosine Kinases; Ribosomal Protein S6 Kinases, 90-kDa; Sunitinib

2008
AMPK Phosphorylation Modulates Pain by Activation of NLRP3 Inflammasome.
    Antioxidants & redox signaling, 2016, Jan-20, Volume: 24, Issue:3

    Topics: Adult; AMP-Activated Protein Kinases; Animals; Carrier Proteins; Female; Fibromyalgia; Humans; Indoles; Inflammasomes; Interleukin-18; Interleukin-1beta; Male; Metformin; Mice; Middle Aged; NLR Family, Pyrin Domain-Containing 3 Protein; Pain; Pain Perception; Phosphorylation; Pyrroles; Sunitinib

2016
Metformin Use and Outcome of Sunitinib Treatment in Patients With Diabetes and Metastatic Renal Cell Carcinoma.
    Clinical genitourinary cancer, 2016, Volume: 14, Issue:5

    Topics: Aged; Aged, 80 and over; Carcinoma, Renal Cell; Comorbidity; Diabetes Mellitus; Disease-Free Survival; Female; Humans; Indoles; Kidney Neoplasms; Male; Metformin; Middle Aged; Neoplasm Metastasis; Proportional Hazards Models; Pyrroles; Retrospective Studies; Sunitinib; Treatment Outcome

2016
Effect of Metformin Use on Survival Outcomes in Patients With Metastatic Renal Cell Carcinoma.
    Clinical genitourinary cancer, 2017, Volume: 15, Issue:2

    Topics: Antineoplastic Agents; Carcinoma, Renal Cell; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Female; Humans; Indoles; Kidney Neoplasms; Male; Metformin; Neoplasm Metastasis; Pyrroles; Retrospective Studies; Sunitinib; Survival Analysis; Treatment Outcome

2017
Targeting the TR4 nuclear receptor-mediated lncTASR/AXL signaling with tretinoin increases the sunitinib sensitivity to better suppress the RCC progression.
    Oncogene, 2020, Volume: 39, Issue:3

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Axl Receptor Tyrosine Kinase; Carcinoma, Renal Cell; Cell Hypoxia; Cell Line, Tumor; Cell Movement; Disease Progression; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; Kidney Neoplasms; Metformin; Mice; Proto-Oncogene Proteins; Receptor Protein-Tyrosine Kinases; Receptors, Steroid; Receptors, Thyroid Hormone; RNA, Long Noncoding; RNA, Small Interfering; Signal Transduction; Sunitinib; Tretinoin; Xenograft Model Antitumor Assays

2020
Metformin Protects Against Sunitinib-induced Cardiotoxicity: Investigating the Role of AMPK.
    Journal of cardiovascular pharmacology, 2022, 06-01, Volume: 79, Issue:6

    Topics: Adenylate Kinase; AMP-Activated Protein Kinases; Animals; Carcinoma, Hepatocellular; Cardiotoxicity; Infarction; Liver Neoplasms; Metformin; Myocytes, Cardiac; Rats; Sunitinib

2022