metformin and stilbenes

metformin has been researched along with stilbenes in 45 studies

Research

Studies (45)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (2.22)	18.2507
2000's	3 (6.67)	29.6817
2010's	40 (88.89)	24.3611
2020's	1 (2.22)	2.80

Authors

Authors	Studies
Chansouria, JP; Jahromi, MA; Manickam, M; Ramanathan, M; Ray, AB	1
Spinney, L	1
Blagosklonny, MV	2
Allison, DB; Nagy, TR; Smith, DL	1
Kim, BJ; Kim, GH; Kim, GS; Kim, SW; Kim, YS; Koh, JM; Lee, KU; Lee, SH; Lee, SY; Lee, YS	1
Cha, HJ; Choi, JS; Kim, JJ; Kim, WS; Lee, JS; Lee, SJ; Min, HG; Park, KY	1
Ebersole, J; González, O; Novak, MJ; Tobia, C	1
Carling, D; Gamblin, SJ; Hardie, DG	1
Boghossian, S; Hawash, A	1
Platanias, LC; Vakana, E	1
Bagul, PK; Banerjee, SK; Bastia, T; Chakravarty, S; Madhusudana, K; Matapally, S; Middela, H; Padiya, R; Reddy, BR	1
Darzynkiewicz, Z; Halicka, HD; Hsieh, TC; Lee, YS; Li, J; Wu, JM; Zhao, H	1
Hofer, A; Kladt, N; Lellek, V; Noe, N; Schauß, A; Tischner, C; Wenz, T	1
Selman, C	1
Valero, T	1
Burkewitz, K; Mair, WB; Zhang, Y	1
Huang, F; Kou, J; Li, J; Liu, B; Liu, K; Qi, L; Sun, Y; Wang, M; Xiao, N	1
Finley, J	1
Bauer, PV; Duca, FA; Hamr, SC; Lam, TK	1
Gao, H; Guo, Q; Teng, S; Wu, Y; Xu, R; Zhang, E	1
Beauloye, C; Bertrand, L; Daskalopoulos, EP; Dufeys, C; Horman, S	1
Huang, F; Kou, J; Li, A; Li, J; Li, X; Liu, B; Liu, K; Qi, LW; Qiu, Z; Wang, L	1
Doonan, BB; Hsieh, TC; Lee, YS; Wu, JM	1
Huffman, DM; LeBrasseur, NK; Schafer, MJ	1
Huang, F; Li, A; Li, J; Liu, B; Liu, K; Zhang, S	1
Feng, X; Hou, T; Li, A; Liu, B; Liu, K; Zhang, N; Zhao, W	1
Frendo-Cumbo, S; MacPherson, RE; Wright, DC	1
Bagul, PK; Banerjee, SK; Chakravarty, S; Jhelum, P; Kaur, G; Kumar, A; Kumar, KP; Maitra, S; Reddy, BR	1
Kang, L; Li, J; Li, Y; Liu, J; Liu, Y; Qi, Z; Shen, Y; Wang, X; Yang, L; Yang, Y; Zhang, Q; Zhu, M; Zu, L	1
Bozza, MT; Carneiro, VC; Feijó, DF; Giarola, NL; Lannes-Vieira, J; Mata-Santos, H; Medei, E; Meyer-Fernandes, JR; Paiva, CN; Paula-Neto, HA; Ramos, IP; Vicentino, AR; Vilar-Pereira, G	1
de Ligt, M; Hansen, J; Hesselink, MK; Kunz, I; Moonen-Kornips, E; Phielix, E; Schaart, G; Schrauwen, P; Schrauwen-Hinderling, VB; Timmers, S; van de Weijer, T	1
Asiedu, MN; Dib-Hajj, SD; Dussor, G; Han, C; Price, TJ; Waxman, SG	1
Cai, GY; Chen, XM; Cui, SY; Dong, D; Fu, B; Guo, YN; Hong, Q; Lv, Y; Ning, YC; Wang, JC	1
deCabo, R; Maxwell, N; Shapiro, D; Stockinger, J; Valdez, G	1
Barger, JL; Cray, NL; Hester, SN; Mastaloudis, A; Newton, MA; Prolla, TA; Pugh, TD; Vann, JM; Weindruch, R; Wood, SM	1
Kosuru, R; Singh, S	1
Chen, J; Fei, DD; Hu, CH; Huang, WT; Jin, Y; Liu, N; Lu, YB; Lv, YJ; Pang, DL; Sui, BD; Xuan, K; Zhao, P; Zheng, CX; Zhou, CH	1
Asiedu, MN; Burton, MD; Dussor, G; Hughes, T; Inyang, K; Lian, B; Mazhar, K; Mejia, GL; Price, TJ; Tillu, DV	1
Byun, S; Lee, E; Lee, KW	1
Klimova, B; Kuca, K; Novotny, M	1
Akash, MSH; Munawar, SM; Rehman, K; Saeed, K	1
Ceylan, S; Eraldemır, C; Furat Rencber, S; Guzel, E; Kum, T; Kurnaz Ozbek, S; Sezer, Z	1
Asadollah, AS; Effat, F; Keihan, GS; Mehdi, F	1
Abd El-Hameed, AM; Abd El-Twab, SM; Abdel-Moneim, A; El-Shahawy, AAG; Yousef, AI	1

Reviews

13 review(s) available for metformin and stilbenes

Article	Year
An anti-aging drug today: from senescence-promoting genes to anti-aging pill. Drug discovery today, 2007, Volume: 12, Issue:5-6 Topics: Aging; Animals; Antioxidants; Caloric Restriction; Cell Cycle Proteins; Cellular Senescence; Drug Delivery Systems; Enzyme Inhibitors; Humans; Immunosuppressive Agents; Longevity; Metformin; Phosphatidylinositol 3-Kinases; Phosphotransferases (Alcohol Group Acceptor); Resveratrol; Saccharomyces cerevisiae Proteins; Sirolimus; Sirtuins; Stilbenes	2007
Validation of anti-aging drugs by treating age-related diseases. Aging, 2009, Mar-28, Volume: 1, Issue:3 Topics: Aging; Animals; Antibiotics, Antineoplastic; Antioxidants; Biomarkers; Chronic Disease; Humans; Hypoglycemic Agents; Metformin; Resveratrol; Sirolimus; Stilbenes; Validation Studies as Topic	2009
Calorie restriction: what recent results suggest for the future of ageing research. European journal of clinical investigation, 2010, Volume: 40, Issue:5 Topics: Animals; Antimetabolites; Biomedical Research; Biomimetics; Caloric Restriction; Deoxyglucose; Enzyme Inhibitors; Hypoglycemic Agents; Longevity; Metformin; Primates; Quality of Life; Resveratrol; Sirolimus; Stilbenes	2010
Caloric restriction and chronic inflammatory diseases. Oral diseases, 2012, Volume: 18, Issue:1 Topics: Adaptive Immunity; Animals; Biomimetics; Caloric Restriction; Cardiovascular Diseases; Chronic Disease; Diabetes Mellitus; Humans; Immunity, Innate; Inflammation; Inflammation Mediators; Insulin-Like Growth Factor I; Metformin; Periodontitis; Resveratrol; Signal Transduction; Sirolimus; Sirtuins; Stilbenes; TOR Serine-Threonine Kinases	2012
AMP-activated protein kinase: also regulated by ADP? Trends in biochemical sciences, 2011, Volume: 36, Issue:9 Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; AMP-Activated Protein Kinases; Animals; Binding Sites; Electron Transport; Energy Metabolism; Enzyme Activation; Fungal Proteins; Glucose; Glycogen; Humans; Metformin; Mitochondria; Phosphorylation; Protein Conformation; Resveratrol; Stilbenes; Transcription, Genetic; Yeasts	2011
Chemoprevention in colorectal cancer--where we stand and what we have learned from twenty year's experience. The surgeon : journal of the Royal Colleges of Surgeons of Edinburgh and Ireland, 2012, Volume: 10, Issue:1 Topics: Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Anticarcinogenic Agents; Colorectal Neoplasms; Histone Deacetylase Inhibitors; Humans; Metformin; Precancerous Conditions; Resveratrol; Selective Estrogen Receptor Modulators; Stilbenes	2012
AMPK in BCR-ABL expressing leukemias. Regulatory effects and therapeutic implications. Oncotarget, 2011, Volume: 2, Issue:12 Topics: AMP-Activated Protein Kinase Kinases; Genes, abl; Hematologic Neoplasms; Humans; Leukemia; Metformin; Phosphatidylinositol 3-Kinase; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Protein Kinases; Proto-Oncogene Proteins c-akt; Resveratrol; Stilbenes; TOR Serine-Threonine Kinases	2011
Dietary restriction and the pursuit of effective mimetics. The Proceedings of the Nutrition Society, 2014, Volume: 73, Issue:2 Topics: Animals; Caloric Restriction; Energy Intake; Genetic Variation; Health; Humans; Longevity; Metformin; Resveratrol; Sirolimus; Stilbenes	2014
AMPK at the nexus of energetics and aging. Cell metabolism, 2014, Jul-01, Volume: 20, Issue:1 Topics: Aging; AMP-Activated Protein Kinases; Animals; Aspirin; Energy Metabolism; Humans; Metabolic Diseases; Metformin; Mitochondria; Neoplasms; Resveratrol; Stilbenes	2014
AMPK in cardiac fibrosis and repair: Actions beyond metabolic regulation. Journal of molecular and cellular cardiology, 2016, Volume: 91 Topics: Aging; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Berberine; Cardiomegaly; Extracellular Matrix Proteins; Fibrosis; Gene Expression Regulation; Humans; Metformin; Myocardial Infarction; Myocardium; Myocytes, Cardiac; Resveratrol; Ribonucleotides; Signal Transduction; Stilbenes; Thiazolidinediones; Wound Healing	2016
Energetic interventions for healthspan and resiliency with aging. Experimental gerontology, 2016, 12-15, Volume: 86 Topics: Aging; Caloric Restriction; Diet; Energy Intake; Exercise; Female; Humans; Longevity; Male; Metformin; Resveratrol; Sirolimus; Stilbenes	2016
Therapeutic Implications of Autophagy Inducers in Immunological Disorders, Infection, and Cancer. International journal of molecular sciences, 2017, Sep-12, Volume: 18, Issue:9 Topics: Adaptive Immunity; Animals; Autoimmune Diseases; Autophagy; Benzylisoquinolines; Cholecalciferol; Humans; Immune System Diseases; Immunity, Innate; Indoles; Infections; Isoquinolines; Lysosomes; Maprotiline; Metformin; Neoplasms; Phenols; Pyrroles; Resveratrol; Sirolimus; Spermidine; Stilbenes; Tetrahydroisoquinolines; Trehalose	2017
Anti-Aging Drugs - Prospect of Longer Life? Current medicinal chemistry, 2018, Volume: 25, Issue:17 Topics: Animals; Humans; Longevity; Metformin; NAD; Quality of Life; Resveratrol; Sirolimus; Stilbenes	2018

Trials

1 trial(s) available for metformin and stilbenes

Article	Year
Resveratrol as Add-on Therapy in Subjects With Well-Controlled Type 2 Diabetes: A Randomized Controlled Trial. Diabetes care, 2016, Volume: 39, Issue:12 Topics: Adult; Aged; Blood Glucose; Cross-Over Studies; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Therapy, Combination; Glucose Clamp Technique; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Male; Metformin; Middle Aged; Resveratrol; Stilbenes	2016

Article

Year

Resveratrol as Add-on Therapy in Subjects With Well-Controlled Type 2 Diabetes: A Randomized Controlled Trial.

Diabetes care, 2016, Volume: 39, Issue:12

Topics: Adult; Aged; Blood Glucose; Cross-Over Studies; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Therapy, Combination; Glucose Clamp Technique; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Male; Metformin; Middle Aged; Resveratrol; Stilbenes

2016

Other Studies

31 other study(ies) available for metformin and stilbenes

Article	Year
Antihyperglycemic activity of phenolics from Pterocarpus marsupium. Journal of natural products, 1997, Volume: 60, Issue:6 Topics: Animals; Benzofurans; Blood Glucose; Body Weight; Cresols; Diabetes Mellitus, Experimental; Female; Glucosides; Hypoglycemic Agents; Male; Metformin; Phenols; Plants, Medicinal; Rats; Stilbenes; Wood	1997
Gerontology: eat your cake and have it. Nature, 2006, Jun-15, Volume: 441, Issue:7095 Topics: Aging; Animals; Caloric Restriction; Cellular Senescence; Drug Evaluation, Preclinical; Drug Industry; Energy Intake; Energy Metabolism; Geriatrics; Ghrelin; Humans; Insulin; Longevity; Metformin; Peptide Hormones; Randomized Controlled Trials as Topic; Reproduction; Resveratrol; Sirtuins; Stilbenes; Time Factors	2006
AMP kinase acts as a negative regulator of RANKL in the differentiation of osteoclasts. Bone, 2010, Volume: 47, Issue:5 Topics: Adenylate Kinase; Animals; Apoptosis; Blotting, Western; Bone Resorption; Catechin; Cell Differentiation; Cell Survival; Cells, Cultured; Macrophage Colony-Stimulating Factor; MAP Kinase Kinase Kinases; Metformin; Mice; Mice, Inbred ICR; Osteoclasts; Osteogenesis; Pyrazoles; Pyrimidines; RANK Ligand; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Stilbenes	2010
Negative regulation of stress-induced matrix metalloproteinase-9 by Sirt1 in skin tissue. Experimental dermatology, 2010, Volume: 19, Issue:12 Topics: Animals; Biocatalysis; Cells, Cultured; Collagen Type IV; Dermis; Female; Fibroblasts; Gene Expression; Gene Expression Regulation, Enzymologic; Humans; Keratinocytes; Matrix Metalloproteinase 9; Metformin; Mice; Mice, Hairless; Resveratrol; Sirtuin 1; Skin; Stilbenes; Tetradecanoylphorbol Acetate; Ultraviolet Rays	2010
Attenuation of insulin resistance, metabolic syndrome and hepatic oxidative stress by resveratrol in fructose-fed rats. Pharmacological research, 2012, Volume: 66, Issue:3 Topics: Animals; Ascorbic Acid; Blood Glucose; Body Weight; Catalase; Eating; Fructose; Glucose Tolerance Test; Glutathione; Insulin; Insulin Resistance; Liver; Male; Metabolic Syndrome; Metformin; NF-E2-Related Factor 2; Nitric Oxide; Oxidative Stress; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Triglycerides; Uric Acid	2012
Potential anti-aging agents suppress the level of constitutive mTOR- and DNA damage- signaling. Aging, 2012, Volume: 4, Issue:12 Topics: Adaptor Proteins, Signal Transducing; Aspirin; Ataxia Telangiectasia Mutated Proteins; Berberine; Cell Cycle Proteins; Cell Line, Tumor; Cellular Senescence; Cholecalciferol; Deoxyglucose; DNA Damage; DNA-Binding Proteins; Down-Regulation; Enzyme Activation; Flow Cytometry; Histones; Humans; Laser Scanning Cytometry; Membrane Potential, Mitochondrial; Metformin; Mitochondria; Oxidative Stress; Phosphoproteins; Phosphorylation; Protein Serine-Threonine Kinases; Reactive Oxygen Species; Resveratrol; Ribosomal Protein S6 Kinases; Signal Transduction; Sirolimus; Stilbenes; TOR Serine-Threonine Kinases; Tumor Suppressor Proteins	2012
Defining the action spectrum of potential PGC-1α activators on a mitochondrial and cellular level in vivo. Human molecular genetics, 2014, May-01, Volume: 23, Issue:9 Topics: Aminoimidazole Carboxamide; Animals; Bezafibrate; HeLa Cells; Humans; Metformin; Mice; Mitochondrial Proteins; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Resveratrol; Ribonucleotides; Rosiglitazone; Signal Transduction; Stilbenes; Thiazolidinediones; Transcription Factors	2014
Mitochondrial biogenesis: pharmacological approaches. Current pharmaceutical design, 2014, Volume: 20, Issue:35 Topics: Animals; DNA, Mitochondrial; Humans; Metformin; Mitochondria; Mitochondrial Diseases; Resveratrol; Stilbenes	2014
Pharmacological activation of AMPK ameliorates perivascular adipose/endothelial dysfunction in a manner interdependent on AMPK and SIRT1. Pharmacological research, 2014, Volume: 89 Topics: Adipokines; Adipose Tissue; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Aorta; Culture Media, Conditioned; Diet; Fructose; Metformin; NF-kappa B; Palmitic Acid; Rats; Resveratrol; Ribonucleotides; Sirtuin 1; Sodium Salicylate; Stilbenes; Vasodilation	2014
Alteration of splice site selection in the LMNA gene and inhibition of progerin production via AMPK activation. Medical hypotheses, 2014, Volume: 83, Issue:5 Topics: Alternative Splicing; AMP-Activated Protein Kinases; Animals; Berberine; DNA, Mitochondrial; Enzyme Activation; Exons; Gene Expression Regulation; Humans; Lamin Type A; Metformin; Models, Biological; Mutation; Nuclear Proteins; Oxidative Phosphorylation; Phosphorylation; Point Mutation; Progeria; Resveratrol; RNA-Binding Proteins; Serine-Arginine Splicing Factors; Stilbenes	2014
Glucoregulatory Relevance of Small Intestinal Nutrient Sensing in Physiology, Bariatric Surgery, and Pharmacology. Cell metabolism, 2015, Sep-01, Volume: 22, Issue:3 Topics: Animals; Bariatric Surgery; Blood Glucose; Brain; Glucose; Glycemic Load; Humans; Hypoglycemic Agents; Intestine, Small; Liver; Metformin; Nutritional Physiological Phenomena; Resveratrol; Stilbenes	2015
Metformin and Resveratrol Inhibited High Glucose-Induced Metabolic Memory of Endothelial Senescence through SIRT1/p300/p53/p21 Pathway. PloS one, 2015, Volume: 10, Issue:12 Topics: Cellular Senescence; Cyclin-Dependent Kinase Inhibitor p21; Dose-Response Relationship, Drug; E1A-Associated p300 Protein; Glucose; Human Umbilical Vein Endothelial Cells; Humans; Metformin; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes; Tumor Suppressor Protein p53	2015
The role of metformin and resveratrol in the prevention of hypoxia-inducible factor 1α accumulation and fibrosis in hypoxic adipose tissue. British journal of pharmacology, 2016, Volume: 173, Issue:12 Topics: 3T3-L1 Cells; Adipose Tissue; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Fibrosis; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Inflammation; Male; Metformin; Mice; Mice, Inbred ICR; Resveratrol; Stilbenes; Structure-Activity Relationship	2016
Combined metformin and resveratrol confers protection against UVC-induced DNA damage in A549 lung cancer cells via modulation of cell cycle checkpoints and DNA repair. Oncology reports, 2016, Volume: 35, Issue:6 Topics: A549 Cells; Aging; Antineoplastic Agents, Phytogenic; CDC2 Protein Kinase; Cell Cycle Proteins; Cell Line, Tumor; Checkpoint Kinase 2; Cyclin B1; Cyclin E; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinases; DNA Damage; DNA Repair; G1 Phase Cell Cycle Checkpoints; Histones; Humans; Metformin; Oncogene Proteins; Resveratrol; Retinoblastoma Protein; Ribonucleotide Reductases; Signal Transduction; Stilbenes; Tumor Suppressor Protein p53; Ultraviolet Rays	2016
Metformin and resveratrol inhibit Drp1-mediated mitochondrial fission and prevent ER stress-associated NLRP3 inflammasome activation in the adipose tissue of diabetic mice. Molecular and cellular endocrinology, 2016, 10-15, Volume: 434 Topics: 3T3-L1 Cells; Adipose Tissue; Animals; Apoptosis; Cell Differentiation; Diabetes Mellitus, Experimental; Dynamins; Endoplasmic Reticulum Stress; Gene Expression Regulation; Inflammasomes; Metformin; Mice; Mitochondria; Mitochondrial Dynamics; NLR Family, Pyrin Domain-Containing 3 Protein; Phosphorylation; Reactive Oxygen Species; Resveratrol; Stilbenes	2016
Metformin and resveratrol ameliorate muscle insulin resistance through preventing lipolysis and inflammation in hypoxic adipose tissue. Cellular signalling, 2016, Volume: 28, Issue:9 Topics: 3T3-L1 Cells; Adipose Tissue; Administration, Oral; Animals; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Diet, High-Fat; Diglycerides; Fatty Acids; Feeding Behavior; Glucose; Hypoxia; Inflammation; Insulin; Insulin Resistance; Lipolysis; Male; Metformin; Mice; Mice, Inbred ICR; Models, Biological; Muscles; Resveratrol; Signal Transduction; Stilbenes	2016
Beneficial effects of combined resveratrol and metformin therapy in treating diet-induced insulin resistance. Physiological reports, 2016, Volume: 4, Issue:15 Topics: Adiposity; Animals; Blood Glucose; Diet, High-Fat; Drug Therapy, Combination; Inflammation Mediators; Insulin Resistance; Male; Metformin; Mice; Mice, Inbred C57BL; Oncogene Protein v-akt; Organ Specificity; Resveratrol; Stilbenes	2016
Sirtuin 1 and 7 mediate resveratrol-induced recovery from hyper-anxiety in high-fructose-fed prediabetic rats. Journal of biosciences, 2016, Volume: 41, Issue:3 Topics: Animals; Antioxidants; Anxiety Disorders; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet; Epigenesis, Genetic; Fructose; Gene Expression Regulation; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Insulin Resistance; Metformin; Prediabetic State; Rats; Resveratrol; Sirtuin 1; Sirtuins; Stilbenes	2016
Metformin potentiates anti-tumor effect of resveratrol on pancreatic cancer by down-regulation of VEGF-B signaling pathway. Oncotarget, 2016, Dec-20, Volume: 7, Issue:51 Topics: Animals; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Cell Survival; Down-Regulation; Drug Synergism; Humans; Hypoglycemic Agents; Metformin; Mice, Nude; Pancreatic Neoplasms; Resveratrol; RNA Interference; Signal Transduction; Stilbenes; Vascular Endothelial Growth Factor B; Xenograft Model Antitumor Assays	2016
Resveratrol Reverses Functional Chagas Heart Disease in Mice. PLoS pathogens, 2016, Volume: 12, Issue:10 Topics: Animals; Antioxidants; Chagas Cardiomyopathy; Cyclic N-Oxides; Disease Models, Animal; Female; Male; Metformin; Mice; Mice, Inbred BALB C; Oxidative Stress; Resveratrol; Spin Labels; Stilbenes	2016
The AMPK Activator A769662 Blocks Voltage-Gated Sodium Channels: Discovery of a Novel Pharmacophore with Potential Utility for Analgesic Development. PloS one, 2017, Volume: 12, Issue:1 Topics: AMP-Activated Protein Kinases; Analgesics; Anesthetics, Local; Animals; Binding Sites; Biphenyl Compounds; Drug Evaluation, Preclinical; HEK293 Cells; Hot Temperature; Humans; Male; meta-Aminobenzoates; Metformin; NAV1.7 Voltage-Gated Sodium Channel; Neural Conduction; Pain; Patch-Clamp Techniques; Pyrones; Rats; Rats, Sprague-Dawley; Reaction Time; Recombinant Fusion Proteins; Resveratrol; Sensory Receptor Cells; Sodium Channel Blockers; Stilbenes; Thiazoles; Thiophenes; Trigeminal Ganglion	2017
Alleviation of senescence and epithelial-mesenchymal transition in aging kidney by short-term caloric restriction and caloric restriction mimetics via modulation of AMPK/mTOR signaling. Oncotarget, 2017, Mar-07, Volume: 8, Issue:10 Topics: Adult; Aging; AMP-Activated Protein Kinases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Western; Caloric Restriction; Cells, Cultured; Cellular Senescence; Epithelial-Mesenchymal Transition; Glucose; Humans; Hypoglycemic Agents; Kidney Tubules, Proximal; Male; Metformin; Microscopy, Fluorescence; Rats, Sprague-Dawley; Resveratrol; Signal Transduction; Stilbenes; TOR Serine-Threonine Kinases	2017
Caloric Restriction Mimetics Slow Aging of Neuromuscular Synapses and Muscle Fibers. The journals of gerontology. Series A, Biological sciences and medical sciences, 2017, Dec-12, Volume: 73, Issue:1 Topics: Aging; Animals; Antioxidants; Caloric Restriction; Cells, Cultured; Disease Models, Animal; Energy Metabolism; Hypoglycemic Agents; Immunohistochemistry; Metformin; Mice; Mice, Inbred C57BL; Motor Disorders; Muscle Fibers, Skeletal; Neuromuscular Junction; Resveratrol; Stilbenes; Synapses	2017
Identification of tissue-specific transcriptional markers of caloric restriction in the mouse and their use to evaluate caloric restriction mimetics. Aging cell, 2017, Volume: 16, Issue:4 Topics: 2,4-Dinitrophenol; Adipose Tissue, White; Aging; Animals; Bezafibrate; Caloric Restriction; Carnitine; Citrate (si)-Synthase; Gene Expression Profiling; Gene Expression Regulation; Glycated Hemoglobin; Interferon-gamma; Male; Metformin; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Inbred DBA; Mice, Inbred Strains; Muscle, Skeletal; Myocardium; Neocortex; Pioglitazone; Quercetin; Resveratrol; Sirtuin 3; Stilbenes; Thiazolidinediones; Tumor Necrosis Factor-alpha	2017
Pterostilbene ameliorates insulin sensitivity, glycemic control and oxidative stress in fructose-fed diabetic rats. Life sciences, 2017, Aug-01, Volume: 182 Topics: Animals; beta-Cyclodextrins; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Fructose; Insulin Resistance; Male; Metabolic Syndrome; Metformin; Oxidative Stress; Rats; Rats, Sprague-Dawley; Stilbenes; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances	2017
Anti-aging pharmacology in cutaneous wound healing: effects of metformin, resveratrol, and rapamycin by local application. Aging cell, 2017, Volume: 16, Issue:5 Topics: Acetyl-CoA Carboxylase; Administration, Cutaneous; Aging; AMP-Activated Protein Kinases; Animals; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p16; Enzyme Activation; Female; Gene Expression Regulation; Metformin; Mice; Neovascularization, Physiologic; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Rats; Rats, Sprague-Dawley; Resveratrol; Ribosomal Protein S6 Kinases; Sirolimus; Skin; Skin Aging; Stilbenes; Tumor Suppressor Protein p53; Wound Healing; Wounds, Nonpenetrating	2017
Pharmacological activation of AMPK inhibits incision-evoked mechanical hypersensitivity and the development of hyperalgesic priming in mice. Neuroscience, 2017, 09-17, Volume: 359 Topics: AMP-Activated Protein Kinases; Analgesics; Animals; Cells, Cultured; Ganglia, Spinal; Hyperalgesia; Male; Metformin; Mice, Inbred ICR; Neurons; Pain; Pain Threshold; Postoperative Complications; Resveratrol; Signal Transduction; Stilbenes	2017
Resveratrol regulates hyperglycemia-induced modulations in experimental diabetic animal model. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 102 Topics: Animals; Antioxidants; Blood Glucose; Calcium; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Hyperglycemia; Insulin; Insulin Resistance; Magnesium; Male; Metformin; Rats; Resveratrol; Stilbenes; Vitamin E	2018
Effect of resveratrol and metformin on ovarian reserve and ultrastructure in PCOS: an experimental study. Journal of ovarian research, 2018, Jun-29, Volume: 11, Issue:1 Topics: AMP-Activated Protein Kinases; Animals; Apoptosis; Cell Count; Dehydroepiandrosterone; Disease Models, Animal; Drug Therapy, Combination; Female; Hormones; Lipid Peroxidation; Metformin; Ovarian Follicle; Ovarian Reserve; Ovary; Polycystic Ovary Syndrome; Rats; Rats, Wistar; Resveratrol; Sirtuin 1; Stilbenes; Tumor Necrosis Factor-alpha; Vagina	2018
The Effects of Resveratrol, Metformin, Cold and Strength Training on the Level of Perilipin 5 in the Heart, Skeletal Muscle and Brown Adipose Tissues in Mouse. Cell biochemistry and biophysics, 2018, Volume: 76, Issue:4 Topics: Adipose Tissue, Brown; Animals; Cold Temperature; Gene Expression Regulation; Lipid Metabolism; Male; Metformin; Mice; Mice, Inbred C57BL; Muscle, Skeletal; Myocardium; Perilipin-5; Physical Conditioning, Animal; Resveratrol; Stilbenes	2018
Hepatoprotective Effects of Polydatin-Loaded Chitosan Nanoparticles in Diabetic Rats: Modulation of Glucose Metabolism, Oxidative Stress, and Inflammation Biomarkers. Biochemistry. Biokhimiia, 2021, Volume: 86, Issue:2 Topics: Animals; Chitosan; Diabetes Mellitus, Experimental; Glucose; Glucosides; Inflammation; Lipid Peroxidation; Liver; Male; Metformin; Nanoparticles; Niacinamide; Oxidative Stress; Protective Agents; Rats; Rats, Wistar; Stilbenes; Streptozocin	2021