Compounds > metformin

metformin and sotorasib

metformin has been researched along with sotorasib in 2 studies

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's2 (100.00)2.80

Authors

AuthorsStudies
Houk, BE; Vuu, I; Wahlstrom, J1
Arrieta, O; Barrios-Bernal, P; Hernández-Pedro, N; Lucio-Lozada, J; Ramos-Ramírez, M1

Other Studies

2 other study(ies) available for metformin and sotorasib

ArticleYear
Impact of Sotorasib on the Pharmacokinetics and Pharmacodynamics of Metformin, a MATE1/2K Substrate, in Healthy Subjects.
    Clinical pharmacokinetics, 2023, Volume: 62, Issue:2

    Topics: Area Under Curve; Carcinoma, Non-Small-Cell Lung; Drug Interactions; Healthy Volunteers; Humans; Lung Neoplasms; Metformin

2023
A Novel Combination of Sotorasib and Metformin Enhances Cytotoxicity and Apoptosis in KRAS-Mutated Non-Small Cell Lung Cancer Cell Lines through MAPK and P70S6K Inhibition.
    International journal of molecular sciences, 2023, Feb-22, Volume: 24, Issue:5

    Topics: Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line; Humans; Lung Neoplasms; Metformin; Mutation; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins p21(ras); Ribosomal Protein S6 Kinases, 70-kDa; TOR Serine-Threonine Kinases

2023