metformin and rosiglitazone-metformin combination

metformin has been researched along with rosiglitazone-metformin combination in 31 studies

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's14 (45.16)29.6817
2010's16 (51.61)24.3611
2020's1 (3.23)2.80

Authors

AuthorsStudies
Del Prato, S; Volpe, L1
Bailey, CJ; Day, C1
Cobitz, A; Garber, A; Huang, C; Rood, J; Rosenstock, J1
Biswas, N; Chou, H; Cobitz, A; Garber, A; Rood, J; Rosenstock, J1
Kanna, B; Pokharna, H1
Bailey, CJ; Chen, H; Donaldson, J; Home, PD; Stewart, MW1
Garber, A1
Balabolkin, MI; Klebanova, EM; Kreminskaia, VM; Kuzin, AG; Mamaeva, GG; Tel'nova, ME1
Cheng, AY; Josse, RG1
Onal, A1
Acusta, AP; Ambery, PD; Bilezikian, JP; Borges, JL; Cobitz, AR; Fitzpatrick, LA; Grosse, M; Jones-Leone, AR; Nino, AJ1
Hanley, AJ; Harris, SB; Retnakaran, R; Ye, C; Zinman, B1
Doubova, SV; Flores-Hernández, S; Mino-León, D; Reyes-Morales, H1
Dyer, C1
Kamal, MF; Khamis, EF; Korany, MA; Mahgoub, H; Youssef, RM1
Coggan, AR; Gropler, RJ; Herrero, P; Lyons, MR; McGill, JB; Peterson, LR; Recklein, C; Saeed, IM; Schechtman, KB1
Bi, Y; Dai, YY; Feng, WH; Hu, J; Hu, Y; Li, P; Liu, YQ; Shao, LL; Shen, SM; Tong, GY; Wang, WM; Xiang, SK; Yang, DH; Yuan, XW; Zhu, DL1
Cai, XL; Chen, YL; Gu, W; Hong, TP; Ji, LN; Li, CJ; Qiu, MC; Shan, ZY; Tian, HM; Xue, YM; Yang, HZ; Yang, JK; Zhao, JJ1
Freeman, R; Mogul, H; Nguyen, K1
El Ghormli, L; Hirst, K; Ievers-Landis, CE; Linder, B; Marcus, MD; van Buren, DJ; Walders-Abramson, N; Wilfley, DE; Zeitler, P1
Arslanian, S; Bacha, F; Caprio, S; El Ghormli, L; Goland, R; Haymond, MW; Levitsky, L; Nadeau, KJ; White, NH; Willi, SM1
Hsieh, CY; Li, CY; Lu, CH; Ou, HT; Yang, CY1
Copeland, KC; Dhaliwal, R; El Ghormli, L; Geffner, ME; Higgins, J; Levitsky, LL; Nadeau, KJ; Shepherd, JA; Weinstock, RS; White, NH1
Chandran, A; Drews, K; El Ghormli, L; Sylvetsky, AC; Talegawkar, SA; Welsh, JA1

Reviews

2 review(s) available for metformin and rosiglitazone-metformin combination

ArticleYear
Rosiglitazone plus metformin: combination therapy for Type 2 diabetes.
    Expert opinion on pharmacotherapy, 2004, Volume: 5, Issue:6

    Topics: Clinical Trials as Topic; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Drug Combinations; Humans; Hypoglycemic Agents; Metformin; Rosiglitazone; Thiazoles; Thiazolidinediones

2004
Avandamet: combined metformin-rosiglitazone treatment for insulin resistance in type 2 diabetes.
    International journal of clinical practice, 2004, Volume: 58, Issue:9

    Topics: Contraindications; Diabetes Mellitus, Type 2; Drug Combinations; Humans; Hypoglycemic Agents; Insulin Resistance; Metformin; Thiazoles; Treatment Outcome

2004

Trials

14 trial(s) available for metformin and rosiglitazone-metformin combination

ArticleYear
Improvement in glycaemic control with rosiglitazone/metformin fixed-dose combination therapy in patients with type 2 diabetes with very poor glycaemic control.
    Diabetes, obesity & metabolism, 2006, Volume: 8, Issue:6

    Topics: Adolescent; Adult; Aged; Blood Glucose; Diabetes Mellitus, Type 2; Drug Administration Schedule; Drug Combinations; Female; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin Resistance; Lipids; Male; Metformin; Middle Aged; Thiazoles; Treatment Outcome

2006
Initial treatment with rosiglitazone/metformin fixed-dose combination therapy compared with monotherapy with either rosiglitazone or metformin in patients with uncontrolled type 2 diabetes.
    Diabetes, obesity & metabolism, 2006, Volume: 8, Issue:6

    Topics: Adolescent; Adult; Aged; Blood Glucose; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Combinations; Female; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Lipids; Male; Metformin; Middle Aged; Rosiglitazone; Thiazoles; Thiazolidinediones; Treatment Outcome

2006
A double-blind randomized study comparing the effects of continuing or not continuing rosiglitazone + metformin therapy when starting insulin therapy in people with Type 2 diabetes.
    Diabetic medicine : a journal of the British Diabetic Association, 2007, Volume: 24, Issue:6

    Topics: Adolescent; Adult; Aged; Blood Glucose; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Europe; Female; Humans; Hypoglycemic Agents; Insulin; Male; Metformin; Middle Aged; Thiazoles; Treatment Outcome

2007
A randomized, parallel group, double-blind, multicentre study comparing the efficacy and safety of Avandamet (rosiglitazone/metformin) and metformin on long-term glycaemic control and bone mineral density after 80 weeks of treatment in drug-naïve type 2 d
    Diabetes, obesity & metabolism, 2011, Volume: 13, Issue:11

    Topics: Adolescent; Adult; Aged; Biomarkers; Blood Glucose; Bone Density; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Combinations; Female; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Thiazoles; Treatment Outcome; Young Adult

2011
Discordant effects on central obesity, hepatic insulin resistance, and alanine aminotransferase of low-dose metformin and thiazolidinedione combination therapy in patients with impaired glucose tolerance.
    Diabetes, obesity & metabolism, 2012, Volume: 14, Issue:1

    Topics: Alanine Transaminase; Blood Glucose; Diabetes Mellitus, Type 2; Drug Combinations; Fatty Liver; Female; Glucose Intolerance; Humans; Hypoglycemic Agents; Insulin Resistance; Liver; Male; Metformin; Obesity, Abdominal; Thiazoles; Waist-Hip Ratio

2012
Treatment effects on measures of body composition in the TODAY clinical trial.
    Diabetes care, 2013, Volume: 36, Issue:6

    Topics: Adolescent; Body Composition; Body Mass Index; Child; Diabetes Mellitus, Type 2; Drug Combinations; Female; Glycated Hemoglobin; Humans; Life Style; Male; Metformin; Thiazoles

2013
Effects of metformin, metformin plus rosiglitazone, and metformin plus lifestyle on insulin sensitivity and β-cell function in TODAY.
    Diabetes care, 2013, Volume: 36, Issue:6

    Topics: Adolescent; Child; Diabetes Mellitus, Type 2; Drug Combinations; Female; Humans; Hypoglycemic Agents; Insulin Resistance; Insulin-Secreting Cells; Life Style; Male; Metformin; Thiazoles

2013
Safety and tolerability of the treatment of youth-onset type 2 diabetes: the TODAY experience.
    Diabetes care, 2013, Volume: 36, Issue:6

    Topics: Adolescent; Blood Glucose; Child; Diabetes Mellitus, Type 2; Drug Combinations; Female; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Male; Metformin; Thiazoles

2013
Impact of sex on the heart's metabolic and functional responses to diabetic therapies.
    American journal of physiology. Heart and circulatory physiology, 2013, Dec-01, Volume: 305, Issue:11

    Topics: Analysis of Variance; Chi-Square Distribution; Diabetes Mellitus, Type 2; Diastole; Dietary Supplements; Docosahexaenoic Acids; Double-Blind Method; Drug Combinations; Echocardiography, Doppler; Eicosapentaenoic Acid; Energy Metabolism; Fatty Acids; Fatty Acids, Omega-3; Female; Health Status Disparities; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Missouri; Myocardium; Positron-Emission Tomography; Recovery of Function; Sex Factors; Stroke Volume; Thiazoles; Time Factors; Treatment Outcome; Triglycerides; Ventricular Function, Left; Ventricular Pressure

2013
Efficacy and safety of avandamet or uptitrated metformin treatment in patients with type 2 diabetes inadequately controlled with metformin alone: a multicenter, randomized, controlled trial.
    Chinese medical journal, 2015, May-20, Volume: 128, Issue:10

    Topics: Adult; Blood Glucose; C-Reactive Protein; Diabetes Mellitus, Type 2; Drug Combinations; Drug Therapy, Combination; Female; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Thiazoles

2015
METFORMIN-SUSTAINED WEIGHT LOSS AND REDUCED ANDROID FAT TISSUE AT 12 MONTHS IN EMPOWIR (ENHANCE THE METABOLIC PROFILE OF WOMEN WITH INSULIN RESISTANCE): A DOUBLE BLIND, PLACEBO-CONTROLLED, RANDOMIZED TRIAL OF NORMOGLYCEMIC WOMEN WITH MIDLIFE WEIGHT GAIN.
    Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists, 2016, Volume: 22, Issue:5

    Topics: Adipose Tissue; Adult; Aging; Body Fat Distribution; Climacteric; Double-Blind Method; Drug Combinations; Female; Humans; Insulin Resistance; Metformin; Middle Aged; Obesity; Overweight; Placebos; Thiazoles; Weight Gain; Weight Loss

2016
Weight change in the management of youth-onset type 2 diabetes: the TODAY clinical trial experience.
    Pediatric obesity, 2017, Volume: 12, Issue:4

    Topics: Adolescent; Anthropometry; Blood Glucose; Body Weight; Child; Diabetes Mellitus, Type 2; Drug Combinations; Female; Humans; Hypoglycemic Agents; Life Style; Male; Metformin; Risk Factors; Thiazoles; Treatment Outcome

2017
Changes in Visceral and Subcutaneous Fat in Youth With Type 2 Diabetes in the TODAY Study.
    Diabetes care, 2019, Volume: 42, Issue:8

    Topics: Adiposity; Adolescent; Blood Glucose; Body Fat Distribution; Child; Combined Modality Therapy; Diabetes Mellitus, Type 2; Drug Combinations; Exercise Therapy; Female; Humans; Insulin Resistance; Intra-Abdominal Fat; Life Style; Male; Metformin; Obesity; Sex Factors; Subcutaneous Fat; Thiazoles

2019
Consumption of Beverages Containing Low-Calorie Sweeteners, Diet, and Cardiometabolic Health in Youth With Type 2 Diabetes.
    Journal of the Academy of Nutrition and Dietetics, 2020, Volume: 120, Issue:8

    Topics: Adolescent; Beverages; Body Mass Index; Cardiometabolic Risk Factors; Child; Diabetes Mellitus, Type 2; Diet; Diet Records; Dietary Sugars; Drug Combinations; Energy Intake; Female; Humans; Life Style; Longitudinal Studies; Male; Metformin; Rosiglitazone; Surveys and Questionnaires; Sweetening Agents; Thiazoles

2020

Other Studies

15 other study(ies) available for metformin and rosiglitazone-metformin combination

ArticleYear
Metaglip and Avandamet for type 2 diabetes.
    The Medical letter on drugs and therapeutics, 2002, Dec-23, Volume: 44, Issue:1146

    Topics: Clinical Trials as Topic; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Combinations; Fees, Pharmaceutical; Glipizide; Humans; Hypoglycemic Agents; Metformin; Thiazoles

2002
Dutasteride (Avodart) for benign prostatic hyperplasia.
    The Medical letter on drugs and therapeutics, 2002, Dec-23, Volume: 44, Issue:1146

    Topics: Abnormalities, Drug-Induced; Administration, Oral; Azasteroids; Biological Availability; Clinical Trials as Topic; Drug Combinations; Dutasteride; Finasteride; Humans; Male; Metformin; Prostatic Hyperplasia; Thiazoles

2002
New drugs and dosage forms.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2003, Oct-01, Volume: 60, Issue:19

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Clobetasol; Dosage Forms; Drug Combinations; Fluorobenzenes; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemic Agents; Imidazoles; Metformin; Pharmaceutical Preparations; Phosphodiesterase Inhibitors; Piperazines; Pyrimidines; Rosuvastatin Calcium; Sulfonamides; Sulfones; Thiazoles; Triazines; United States; United States Food and Drug Administration; Vardenafil Dihydrochloride

2003
[Blood sugar inspite of maximal metformin dosage. New fixed combination forces HbA1c down].
    MMW Fortschritte der Medizin, 2003, Dec-11, Volume: 145, Issue:50

    Topics: Body Mass Index; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Drug Combinations; Drug Therapy, Combination; Follow-Up Studies; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Metformin; Patient Compliance; Placebos; Rosiglitazone; Thiazoles; Thiazolidinediones; Time Factors

2003
Letter to the editor in reference to article titled: Initial treatment with rosiglitazone/metformin fixed-dose combination therapy compared with monotherapy with either rosiglitazone or metformin in patients with uncontrolled type 2 diabetes.
    Diabetes, obesity & metabolism, 2007, Volume: 9, Issue:6

    Topics: Diabetes Mellitus, Type 2; Drug Combinations; Humans; Hypoglycemic Agents; Metformin; Randomized Controlled Trials as Topic; Rosiglitazone; Thiazoles; Thiazolidinediones

2007
Response to Pokharna and Kanna: initial treatment with rosiglitazone/metformin fixed-dose combination therapy compared with monotherapy with either rosiglitazone or metformin in patients with uncontrolled type 2 diabetes.
    Diabetes, obesity & metabolism, 2008, Volume: 10, Issue:5

    Topics: Confounding Factors, Epidemiologic; Data Interpretation, Statistical; Diabetes Mellitus, Type 2; Drug Combinations; Humans; Hypoglycemic Agents; Metformin; Rosiglitazone; Thiazoles; Thiazolidinediones

2008
[Avandia and avandamet in the treatment of patients with diabetes mellitus type 2: effects on secretion of some fat tissue hormones].
    Terapevticheskii arkhiv, 2008, Volume: 80, Issue:10

    Topics: Adiponectin; Adipose Tissue; Diabetes Mellitus, Type 2; Drug Combinations; Female; Fibrinolytic Agents; Ghrelin; Humans; Hypoglycemic Agents; Insulin; Leptin; Male; Metformin; Middle Aged; Resistin; Rosiglitazone; Thiazoles; Thiazolidinediones

2008
Rosiglitazone maleate + metformin hydrochloride extend: review of an emerging compound.
    Expert opinion on investigational drugs, 2009, Volume: 18, Issue:9

    Topics: Clinical Trials, Phase III as Topic; Diabetes Mellitus, Type 2; Drug Combinations; Gluconeogenesis; Humans; Hypoglycemic Agents; Metformin; Molecular Structure; Thiazoles; Treatment Outcome

2009
Spectrophotometric and HPLC determinations of anti-diabetic drugs, rosiglitazone maleate and metformin hydrochloride, in pure form and in pharmaceutical preparations.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:12

    Topics: Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Drug Combinations; Hypoglycemic Agents; Metformin; Molecular Structure; Rosiglitazone; Spectrophotometry; Tablets; Thiazoles; Thiazolidinediones

2009
Postmarketing pharmacovigilance of adverse drug reactions: the case of rosiglitazone in Mexico.
    International journal of clinical pharmacology and therapeutics, 2012, Volume: 50, Issue:1

    Topics: Administration, Oral; Adult; Aged; Diabetes Mellitus, Type 2; Drug Combinations; Edema; Female; Follow-Up Studies; Glyburide; Humans; Hypoglycemic Agents; Male; Medication Adherence; Metformin; Mexico; Middle Aged; Pharmacovigilance; Prospective Studies; Rosiglitazone; Thiazoles; Thiazolidinediones; Weight Gain

2012
GSK fights compensation claims from UK patients who took rosiglitazone.
    BMJ (Clinical research ed.), 2013, Feb-01, Volume: 346

    Topics: Compensation and Redress; Drug Combinations; Drug Industry; Humans; Hypoglycemic Agents; Metformin; Rosiglitazone; Safety-Based Drug Withdrawals; Thiazoles; Thiazolidinediones; United Kingdom

2013
Development and validation of spectrophotometric and HPTLC methods for simultaneous determination of rosiglitazone maleate and metformin hydrochloride in the presence of interfering matrix excipients.
    Drug development and industrial pharmacy, 2014, Volume: 40, Issue:9

    Topics: Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Drug Combinations; Excipients; Metformin; Spectrophotometry; Tablets; Thiazoles

2014
Correlated increase of omentin-1 and adiponectin by exenatide, avandamet and dietary change in diet-induced obese rats.
    Folia biologica, 2013, Volume: 59, Issue:6

    Topics: Adiponectin; Animals; Cytokines; Drug Combinations; Exenatide; Metformin; Obesity; Peptides; Rats; Thiazoles; Venoms

2013
Adiponectin, Insulin Sensitivity, β-Cell Function, and Racial/Ethnic Disparity in Treatment Failure Rates in TODAY.
    Diabetes care, 2017, Volume: 40, Issue:1

    Topics: Adiponectin; Adolescent; Black People; Blood Glucose; C-Peptide; Child; Diabetes Mellitus, Type 2; Drug Combinations; Ethnicity; Female; Glucose Tolerance Test; Health Status Disparities; Hispanic or Latino; Humans; Hypoglycemic Agents; Insulin Resistance; Life Style; Male; Metformin; Thiazoles; Treatment Failure; White People

2017
Lower risk of dementia with pioglitazone, compared with other second-line treatments, in metformin-based dual therapy: a population-based longitudinal study.
    Diabetologia, 2018, Volume: 61, Issue:3

    Topics: Aged; Dementia; Diabetes Mellitus, Type 2; Drug Combinations; Female; Humans; Hypoglycemic Agents; Longitudinal Studies; Male; Metformin; Pioglitazone; Thiazoles; Thiazolidinediones

2018