metformin has been researched along with ranitidine in 32 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (21.88) | 29.6817 |
| 2010's | 18 (56.25) | 24.3611 |
| 2020's | 7 (21.88) | 2.80 |
| Authors | Studies |
|---|---|
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Benet, LZ; Brouwer, KL; Chu, X; Dahlin, A; Evers, R; Fischer, V; Giacomini, KM; Hillgren, KM; Hoffmaster, KA; Huang, SM; Ishikawa, T; Keppler, D; Kim, RB; Lee, CA; Niemi, M; Polli, JW; Sugiyama, Y; Swaan, PW; Tweedie, DJ; Ware, JA; Wright, SH; Yee, SW; Zamek-Gliszczynski, MJ; Zhang, L | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A | 1 |
| Giacomini, KM; Huang, Y; Khuri, N; Kido, Y; Kosaka, A; Morrissey, KM; Sali, A; Wittwer, MB; Zhang, X; Zur, AA | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Blomgren, A; Börjesson, L; Gustavsson, L; Hendrickx, R; Jenvert, RM; Johansson, JG; Lohmann, C | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Ahmed, N; Arayne, MS; Sultana, N | 1 |
| Iwatsubo, T; Kamimura, H; Noguchi, K; Umehara, KI | 1 |
| Arayne, MS; Siddiqui, FA; Sultana, N; Zuberi, MH | 1 |
| Johansson, S; Leese, PT; Li, Y; Lisbon, E; Martin, P; Mathews, D; Oliver, S; Read, J; Steinberg, M | 1 |
| Chang, F; Miao, Y; O'Hare, AM; Steinman, MA | 1 |
| Cho, SK; Chung, JY | 1 |
| Afonso-Pereira, F; Basit, AW; Mai, Y; Murdan, S | 1 |
| Basit, AW; Dou, L; Madla, CM; Mai, Y; Orlu, M | 1 |
| Lim, HH; Oh, YS; Shin, HS | 1 |
| Kumar, P; Sarmah, B; Shaik, KM; Wadekar, GS | 1 |
| Alican, İ; Aydın, B; Cabadak, H; Cumbul, A; Ercan, F; İpek, BE; Yüksel, M | 1 |
| Chang, CC; Chang, SH; Ho, HY; Hsu, YH; Lin, MC; Tseng, SH; Wang, DY; Zang, CZ | 1 |
| Agarwal, SM; Ahsan, ZA; Cohn, T; Duncan, MJ; Faulkner, GEJ; Hahn, M; Lockwood, JT; Remington, G; Stogios, N; Takeuchi, H; Taylor, VH | 1 |
| Attakora, J; Donkoh, IE; Ephraim, RKD; Essuman, G; Okyere, I; Okyere, P; Serwaa, D | 1 |
| Khuhawar, MY; Khuhawar, TMJ; Lanjwani, MF; Zounr, RA | 1 |
4 review(s) available for metformin and ranitidine
| Article | Year |
|---|---|
Membrane transporters in drug development.
Topics: Animals; Computer Simulation; Decision Trees; Drug Approval; Drug Discovery; Drug Evaluation, Preclinical; Drug Interactions; Humans; Membrane Transport Proteins; Mice; Mice, Knockout; Prescription Drugs | 2010 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Regulatory Updates and Analytical Methodologies for Nitrosamine Impurities Detection in Sartans, Ranitidine, Nizatidine, and Metformin along with Sample Preparation Techniques.
Topics: Angiotensin II Type 1 Receptor Blockers; Chromatography, Liquid; Metformin; Nitrosamines; Nizatidine; Ranitidine; Tandem Mass Spectrometry | 2022 |
Pharmacological interventions for prevention of weight gain in people with schizophrenia.
Topics: Antipsychotic Agents; Betahistine; Famotidine; Fluoxetine; Humans; Melatonin; Metformin; Nausea; Nizatidine; Ranitidine; Reboxetine; Schizophrenia; Topiramate; Weight Gain | 2022 |
1 trial(s) available for metformin and ranitidine
| Article | Year |
|---|---|
Pharmacokinetic evaluations of the co-administrations of vandetanib and metformin, digoxin, midazolam, omeprazole or ranitidine.
Topics: Adolescent; Adult; Area Under Curve; Digoxin; Drug Interactions; Female; Humans; Male; Metformin; Midazolam; Middle Aged; Omeprazole; Piperidines; Quinazolines; Ranitidine; Young Adult | 2014 |
27 other study(ies) available for metformin and ranitidine
| Article | Year |
|---|---|
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics | 2011 |
Discovery of potent, selective multidrug and toxin extrusion transporter 1 (MATE1, SLC47A1) inhibitors through prescription drug profiling and computational modeling.
Topics: Computer Simulation; Fluorescent Dyes; Organic Cation Transport Proteins; Prescription Drugs | 2013 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Identification of novel substrates and structure-activity relationship of cellular uptake mediated by human organic cation transporters 1 and 2.
Topics: Biological Transport; Chemical Phenomena; Drug Evaluation, Preclinical; HEK293 Cells; Humans; Organic Cation Transport Proteins; Organic Cation Transporter 1; Organic Cation Transporter 2; Pharmaceutical Preparations; Reproducibility of Results; Structure-Activity Relationship; Substrate Specificity | 2013 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
In vitro availability of metformin in presence of h(2) receptor antagonists.
Topics: Cimetidine; Famotidine; Gastric Juice; Histamine H2 Antagonists; Hydrogen-Ion Concentration; Intestinal Secretions; Metformin; Ranitidine | 2006 |
Comparison of the kinetic characteristics of inhibitory effects exerted by biguanides and H2-blockers on human and rat organic cation transporter-mediated transport: Insight into the development of drug candidates.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Biguanides; Cell Line; Cimetidine; Drug Design; Famotidine; Histamine H2 Antagonists; Humans; Ion Transport; Kinetics; Metformin; Organic Cation Transport Proteins; Phenformin; Ranitidine; Rats; Tetraethylammonium | 2007 |
Simultaneous determination of metformin, cimetidine, famotidine, and ranitidine in human serum and dosage formulations using HPLC with UV detection.
Topics: Adult; Chromatography, High Pressure Liquid; Cimetidine; Ethylamines; Famotidine; Histamine H2 Antagonists; Humans; Hydrogen-Ion Concentration; Linear Models; Metformin; Methanol; Ranitidine; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Tablets; Young Adult | 2010 |
Use of Renally Inappropriate Medications in Older Veterans: A National Study.
Topics: Aged; Aged, 80 and over; Allopurinol; Aminohydrolases; Body Weight; Comorbidity; Cross-Sectional Studies; Female; Humans; Inappropriate Prescribing; Male; Metformin; Ranitidine; Renal Insufficiency, Chronic; Retrospective Studies; United States; Veterans | 2015 |
The MATE1 rs2289669 polymorphism affects the renal clearance of metformin following ranitidine treatment.
Topics: Adult; Drug Interactions; Female; Humans; Hypoglycemic Agents; Kidney; Male; Metabolic Clearance Rate; Metformin; Organic Cation Transport Proteins; Organic Cation Transporter 2; Polymorphism, Genetic; Prospective Studies; Ranitidine | 2016 |
Excipient-mediated alteration in drug bioavailability in the rat depends on the sex of the animal.
Topics: Ampicillin; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Availability; Cyclosporine; Excipients; Female; Male; Metformin; Polyethylene Glycols; Ranitidine; Rats, Wistar; Sex Factors | 2017 |
P-glycoprotein expression in the gastrointestinal tract of male and female rats is influenced differently by food.
Topics: Animal Feed; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Colon; Duodenum; Eating; Fasting; Female; Ganciclovir; Ileum; Intestinal Absorption; Intestine, Small; Jejunum; Male; Metformin; Permeability; Postprandial Period; Ranitidine; Rats, Wistar | 2018 |
Determination of N-nitrosodimethylamine and N-nitrosomethylethylamine in drug substances and products of sartans, metformin and ranitidine by precipitation and solid phase extraction and gas chromatography-tandem mass spectrometry.
Topics: Angiotensin II Type 1 Receptor Blockers; Dimethylnitrosamine; Gas Chromatography-Mass Spectrometry; Metformin; Pharmaceutical Preparations; Ranitidine; Solid Phase Extraction; Tandem Mass Spectrometry | 2020 |
The Effect of Metformin on Ethanol- and IndomethacinInduced Gastric Ulcers in Rats.
Topics: Animals; Anti-Ulcer Agents; Antioxidants; DNA Nucleotidylexotransferase; Ethanol; Gastric Mucosa; Indomethacin; Interleukin-1beta; Male; Metformin; Ranitidine; Rats; Rats, Sprague-Dawley; Stomach Ulcer | 2022 |
Evaluation and optimization of a HS-SPME-assisted GC-MS/MS method for monitoring nitrosamine impurities in diverse pharmaceuticals.
Topics: Angiotensin II Type 1 Receptor Blockers; Diethylnitrosamine; Dimethylnitrosamine; Gas Chromatography-Mass Spectrometry; Metformin; Nitrosamines; Pharmaceutical Preparations; Ranitidine; Sodium Chloride; Solid Phase Microextraction; Tandem Mass Spectrometry | 2022 |
Conservative therapy is associated with worse clinical features and biochemical derangements than renal replacement therapy: a retrospective study in Kumasi, Ghana.
Topics: Adult; Aspirin; Bisoprolol; Conservative Treatment; Furosemide; Ghana; Humans; Irbesartan; Kidney Failure, Chronic; Lisinopril; Metformin; Middle Aged; Nifedipine; Ranitidine; Renal Replacement Therapy; Retrospective Studies; Sodium | 2022 |
GC Analysis of Metformin, Ranitidine and Famotidine from Pharmaceuticals and Human Serum.
Topics: Chromatography, Gas; Famotidine; Humans; Metformin; Pharmaceutical Preparations; Ranitidine | 2023 |