metformin has been researched along with quercetin in 23 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (8.70) | 29.6817 |
| 2010's | 13 (56.52) | 24.3611 |
| 2020's | 8 (34.78) | 2.80 |
| Authors | Studies |
|---|---|
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Blowers, EC; Natarajan, A; Rana, S | 1 |
| Fan, Z; Lu, K; Ma, Y; Pan, G; Xiao, N; Yang, K; Yao, Q; Yu, P; Zhang, Y; Zhao, L; Zhao, X | 1 |
| Agard, DA; Ashworth, A; Barrio-Hernandez, I; Batra, J; Beltrao, P; Bennett, MJ; Bohn, M; Bouhaddou, M; Braberg, H; Broadhurst, DJ; Cai, Y; Cakir, M; Calviello, L; Cavero, DA; Chang, JCJ; Chorba, JS; Craik, CS; d'Enfert, C; Dai, SA; Eckhardt, M; Emerman, M; Fabius, JM; Fletcher, SJ; Floor, SN; Foussard, H; Frankel, AD; Fraser, JS; Fujimori, DG; Ganesan, SJ; García-Sastre, A; Gordon, DE; Gross, JD; Guo, JZ; Haas, K; Haas, P; Hernandez-Armenta, C; Hiatt, J; Huang, XP; Hubert, M; Hüttenhain, R; Ideker, T; Jacobson, M; Jang, GM; Jura, N; Kaake, RM; Kim, M; Kirby, IT; Klippsten, S; Koh, C; Kortemme, T; Krogan, NJ; Kuzuoglu-Ozturk, D; Li, Q; Liboy-Lugo, J; Lin, Y; Liu, X; Liu, Y; Lou, K; Lyu, J; Mac Kain, A; Malik, HS; Mathy, CJP; McGregor, MJ; Melnyk, JE; Memon, D; Meyer, B; Miorin, L; Modak, M; Moreno, E; Mukherjee, S; Naing, ZZC; Noack, J; O'Meara, MJ; O'Neal, MC; Obernier, K; Ott, M; Peng, S; Perica, T; Pilla, KB; Polacco, BJ; Rakesh, R; Rathore, U; Rezelj, VV; Richards, AL; Roesch, F; Rosenberg, OS; Rosenthal, SB; Roth, BL; Roth, TL; Ruggero, D; Safari, M; Sali, A; Saltzberg, DJ; Savar, NS; Schwartz, O; Sharp, PP; Shen, W; Shengjuler, D; Shi, Y; Shoichet, BK; Shokat, KM; Soucheray, M; Stroud, RM; Subramanian, A; Swaney, DL; Taunton, J; Tran, QD; Trenker, R; Tummino, TA; Tutuncuoglu, B; Ugur, FS; Vallet, T; Venkataramanan, S; Verba, KA; Verdin, E; Vignuzzi, M; von Zastrow, M; Wang, HY; Wankowicz, SA; Wenzell, NA; White, KM; Xu, J; Young, JM; Zhang, Z; Zhou, Y | 1 |
| Chen, S; Han, J; Li, Z; Liu, T; Wang, M; Wu, M | 1 |
| Anuradha, CV; Kannappan, S | 1 |
| Balk, B; Bujok, K; Fromm, MF; Glaeser, H; Mandery, K; Schmidt, I | 1 |
| Ahrens, MJ; Thompson, DL | 1 |
| Dong, Z; Duan, H; Ji, X; Jiang, P; Li, M; Li, X; Ma, B; Ma, X; Ni, Z; Wang, B; Wei, Q | 1 |
| Barger, JL; Cray, NL; Hester, SN; Mastaloudis, A; Newton, MA; Prolla, TA; Pugh, TD; Vann, JM; Weindruch, R; Wood, SM | 1 |
| Carani Venkatraman, A; Mutlur Krishnamoorthy, R | 1 |
| Gong, F; Liu, P; Miao, Q; Sun, S | 1 |
| Angiolillo, C; Cirone, M; D'Orazi, G; Faggioni, A; Gilardini Montani, MS; Granato, M | 1 |
| Dehghanian, A; Jamali, N; Mostafavi-Pour, Z; Poordast, T; Samare-Najaf, M; Zal, F | 1 |
| Chen, Z; Hong, X; Lin, Q; Luo, L; Zeng, Y; Zeng, Z; Zhu, S | 1 |
| Chai, HC; Chua, KH; Lim, SK; Mahendran, R; Ong, KC | 1 |
| Achyut, A; Amir, Z; Amna, N; Fazle, R; Irfan, U; Shafiq Ur, R | 1 |
| Chellappan, DK; Chellian, J; Krishnappa, P; Mak, KK; Pichika, MR | 1 |
| Corremans, R; D'Haese, PC; Dams, G; Verhulst, A; Vervaet, BA | 1 |
2 review(s) available for metformin and quercetin
| Article | Year |
|---|---|
Small molecule adenosine 5'-monophosphate activated protein kinase (AMPK) modulators and human diseases.
Topics: Adenine Nucleotides; Allosteric Regulation; AMP-Activated Protein Kinases; Humans; Intracellular Signaling Peptides and Proteins; Metabolic Diseases; Molecular Structure; Neoplasms; Protein Structure, Tertiary; Small Molecule Libraries | 2015 |
Natural-derived compounds and their mechanisms in potential autosomal dominant polycystic kidney disease (ADPKD) treatment.
Topics: Antioxidants; Chalcones; Curcumin; Diterpenes; Diterpenes, Kaurane; Emodin; Epoxy Compounds; Estrogen Antagonists; Flavanones; Humans; Hypoglycemic Agents; Metformin; Phenanthrenes; Plant Extracts; Polycystic Kidney, Autosomal Dominant; Protein Kinase Inhibitors; Quercetin; Resveratrol | 2021 |
1 trial(s) available for metformin and quercetin
| Article | Year |
|---|---|
Effect of emulin on blood glucose in type 2 diabetics.
Topics: Adolescent; Adult; Area Under Curve; Blood Glucose; Chlorogenic Acid; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Combinations; Female; Flavonoids; Humans; Hypoglycemic Agents; Male; Metformin; Phytotherapy; Plant Extracts; Postprandial Period; Quercetin | 2013 |
20 other study(ies) available for metformin and quercetin
| Article | Year |
|---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Identification of potent Yes1 kinase inhibitors using a library screening approach.
Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship | 2013 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Total synthesis of 8-(6″-umbelliferyl)-apigenin and its analogs as anti-diabetic reagents.
Topics: 3T3-L1 Cells; Adipocytes; Alkylation; Animals; Apigenin; Chemistry Techniques, Synthetic; Drug Design; Glucose; Hypoglycemic Agents; Mice | 2016 |
A SARS-CoV-2 protein interaction map reveals targets for drug repurposing.
Topics: Animals; Antiviral Agents; Betacoronavirus; Chlorocebus aethiops; Cloning, Molecular; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Drug Evaluation, Preclinical; Drug Repositioning; HEK293 Cells; Host-Pathogen Interactions; Humans; Immunity, Innate; Mass Spectrometry; Molecular Targeted Therapy; Pandemics; Pneumonia, Viral; Protein Binding; Protein Biosynthesis; Protein Domains; Protein Interaction Mapping; Protein Interaction Maps; Receptors, sigma; SARS-CoV-2; SKP Cullin F-Box Protein Ligases; Vero Cells; Viral Proteins | 2020 |
Design and synthesis of 3-(4-pyridyl)-5-(4-sulfamido-phenyl)-1,2,4-oxadiazole derivatives as novel GSK-3β inhibitors and evaluation of their potential as multifunctional anti-Alzheimer agents.
Topics: Alzheimer Disease; Animals; Cognition; Drug Design; Enzyme Inhibitors; Glucose; Glycogen Synthase Kinase 3 beta; Hep G2 Cells; Humans; Male; Mice, Inbred C57BL; Molecular Docking Simulation; Oxadiazoles; Reactive Oxygen Species | 2021 |
Insulin sensitizing actions of fenugreek seed polyphenols, quercetin & metformin in a rat model.
Topics: Animals; Blood Glucose; Fatty Acids, Nonesterified; Flavonoids; Fructose; Glucose Tolerance Test; Insulin; Insulin Resistance; Liver; Male; Metformin; Phenols; Plant Extracts; Polyphenols; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Quercetin; Rats; Rats, Wistar; Seeds; Triglycerides; Trigonella | 2009 |
Inhibition of hepatic uptake transporters by flavonoids.
Topics: 1-Methyl-4-phenylpyridinium; Apigenin; Atorvastatin; Biological Transport; Flavanones; Flavonoids; Food-Drug Interactions; HEK293 Cells; Hepatocytes; Heptanoic Acids; Humans; Inhibitory Concentration 50; Kaempferols; Liver-Specific Organic Anion Transporter 1; Metformin; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Organic Cation Transporter 1; Pyrroles; Quercetin; Rutin; Solute Carrier Organic Anion Transporter Family Member 1B3; Sulfobromophthalein; Tritium | 2012 |
Effect of Vanadyl Rosiglitazone, a New Insulin-Mimetic Vanadium Complexes, on Glucose Homeostasis of Diabetic Mice.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Disease Models, Animal; Drinking Behavior; Feeding Behavior; Homeostasis; Insulin; Male; Metformin; Mice; Quercetin; Rosiglitazone; Spectrophotometry, Infrared; Thiazolidinediones; Trehalose; Vanadium | 2016 |
Identification of tissue-specific transcriptional markers of caloric restriction in the mouse and their use to evaluate caloric restriction mimetics.
Topics: 2,4-Dinitrophenol; Adipose Tissue, White; Aging; Animals; Bezafibrate; Caloric Restriction; Carnitine; Citrate (si)-Synthase; Gene Expression Profiling; Gene Expression Regulation; Glycated Hemoglobin; Interferon-gamma; Male; Metformin; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Inbred DBA; Mice, Inbred Strains; Muscle, Skeletal; Myocardium; Neocortex; Pioglitazone; Quercetin; Resveratrol; Sirtuin 3; Stilbenes; Thiazolidinediones; Tumor Necrosis Factor-alpha | 2017 |
Polyphenols activate energy sensing network in insulin resistant models.
Topics: AMP-Activated Protein Kinases; Animals; Blood Glucose; Cell Differentiation; Cell Line; Cell Survival; Diabetes Mellitus, Type 2; Disease Models, Animal; Energy Metabolism; Flavanones; Glucose Transporter Type 4; Insulin; Insulin Resistance; Male; Metformin; Muscle Fibers, Skeletal; Palmitates; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Phosphorylation; Polyphenols; Quercetin; Rats; Rats, Wistar; Sirtuin 1 | 2017 |
Metformin combined with quercetin synergistically repressed prostate cancer cells via inhibition of VEGF/PI3K/Akt signaling pathway.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Caspases; Cell Line, Tumor; Down-Regulation; Drug Synergism; Humans; Male; Metformin; Mice; Mice, Nude; Phosphatidylinositol 3-Kinases; Prostatic Neoplasms; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Quercetin; Signal Transduction; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays | 2018 |
Cytotoxic Drugs Activate KSHV Lytic Cycle in Latently Infected PEL Cells by Inducing a Moderate ROS Increase Controlled by HSF1, NRF2 and p62/SQSTM1.
Topics: Antineoplastic Agents; Bortezomib; Butyric Acid; Cell Line, Tumor; Down-Regulation; Heat Shock Transcription Factors; Herpesvirus 8, Human; Humans; Metformin; NF-E2-Related Factor 2; Quercetin; Reactive Oxygen Species; RNA-Binding Proteins; Sequestosome-1 Protein; Tetradecanoylphorbol Acetate; Trans-Activators; Transcriptional Activation; Virus Activation; Virus Latency | 2018 |
Ameliorative Effects of Quercetin and Metformin and Their Combination Against Experimental Endometriosis in Rats.
Topics: Animals; Autophagy; Autophagy-Related Protein 5; Beclin-1; Disease Models, Animal; Drug Therapy, Combination; Endometriosis; Endometrium; Estradiol; Female; Metformin; NAD(P)H Dehydrogenase (Quinone); NF-E2-Related Factor 2; Oxidative Stress; Quercetin; Rats, Sprague-Dawley; Signal Transduction; TOR Serine-Threonine Kinases; Tumor Necrosis Factor-alpha | 2021 |
Effects of different combined regimens of cisplatin, metformin, and quercetin on nasopharyngeal carcinoma cells and subcutaneous xenografts.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Cisplatin; Heterografts; Humans; Injections, Subcutaneous; Male; Metformin; Mice; Mice, Inbred BALB C; Mice, Nude; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Neoplasm Transplantation; Quercetin | 2021 |
Detailed approach toward the anti-hyperglycemic potential of Sterculia diversifolia G. Don against alloxan-induced in vivo hyperglycemia model.
Topics: Alloxan; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Humans; Hyperglycemia; Hypoglycemic Agents; Kaempferols; Metformin; Mice; Phytochemicals; Plant Extracts; Quercetin; Sterculia | 2022 |
Quercetin and metformin synergistically reverse endothelial dysfunction in the isolated aorta of streptozotocin-nicotinamide- induced diabetic rats.
Topics: Animals; Diabetes Mellitus, Experimental; Endothelium, Vascular; Hypoglycemic Agents; Metformin; Niacinamide; Quercetin; Rats; Streptozocin; Vascular Diseases | 2022 |
Metformin and Canagliflozin Are Equally Renoprotective in Diabetic Kidney Disease but Have No Synergistic Effect.
Topics: Animals; Canagliflozin; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Hyperglycemia; Kidney; Male; Metformin; NF-kappa B; Quercetin; Rats; Rats, Wistar | 2023 |