metformin and pyrazinamide

metformin has been researched along with pyrazinamide in 13 studies

Research

Studies (13)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (7.69)	18.2507
2000's	1 (7.69)	29.6817
2010's	10 (76.92)	24.3611
2020's	1 (7.69)	2.80

Authors

Authors	Studies
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
A-Rahim, YI; Beyer, KH; Vesell, ES	1
Jung, JA; Kaisar, N; Parvez, MM; Shin, HJ; Shin, JG	1
Dutta, NK; Karakousis, PC; Pinn, ML	1
Ahmed, M; Ali, M; Ayatollahi, SA; Esfahanizadeh, M; Haider, SM; Hasan, A; Khan, KM; Kobarfard, F	1
Ali, M; Mertaniasih, NM; Novita, BD; Pranoto, A; Soediono, EI	1
Balganesh, T; Bhavani, PK; Gomathy, SN; Guleria, R; Jawahar, SM; Kumar, H; Natrajan, M; Padmapriyadarsini, C; Ponnuraja, C; Singh, M; Swaminathan, S	1
Bharathiraja, T; Hemanth Kumar, AK; Kannan, T; Lavanya, J; Mary Rebecca, Y; Sudha, V	1

Reviews

1 review(s) available for metformin and pyrazinamide

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Trials

1 trial(s) available for metformin and pyrazinamide

Article	Year
Evaluation of metformin in combination with rifampicin containing antituberculosis therapy in patients with new, smear-positive pulmonary tuberculosis (METRIF): study protocol for a randomised clinical trial. BMJ open, 2019, 03-01, Volume: 9, Issue:3 Topics: Adult; Antibiotics, Antitubercular; Drug Combinations; Drug Therapy, Combination; Ethambutol; Humans; India; Isoniazid; Metformin; Multicenter Studies as Topic; Mycobacterium tuberculosis; Pyrazinamide; Randomized Controlled Trials as Topic; Rifampin; Tuberculosis, Pulmonary	2019

Article

Year

Evaluation of metformin in combination with rifampicin containing antituberculosis therapy in patients with new, smear-positive pulmonary tuberculosis (METRIF): study protocol for a randomised clinical trial.

BMJ open, 2019, 03-01, Volume: 9, Issue:3

Topics: Adult; Antibiotics, Antitubercular; Drug Combinations; Drug Therapy, Combination; Ethambutol; Humans; India; Isoniazid; Metformin; Multicenter Studies as Topic; Mycobacterium tuberculosis; Pyrazinamide; Randomized Controlled Trials as Topic; Rifampin; Tuberculosis, Pulmonary

2019

Other Studies

11 other study(ies) available for metformin and pyrazinamide

Article	Year
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data. European journal of medicinal chemistry, 2009, Volume: 44, Issue:11 Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Studies on pyrazinoylguanidine. 2. Comparative drug and dose effects on glucose and lipid metabolism in streptozotocin-induced diabetic rats. Pharmacology, 1996, Volume: 52, Issue:3 Topics: Analysis of Variance; Animals; Anti-Bacterial Agents; Blood Glucose; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Glyburide; Guanidines; Hypoglycemic Agents; Hypolipidemic Agents; Lipid Metabolism; Male; Metformin; Pyrazinamide; Pyrazines; Rats; Rats, Sprague-Dawley; Streptozocin	1996
Inhibitory Interaction Potential of 22 Antituberculosis Drugs on Organic Anion and Cation Transporters of the SLC22A Family. Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:11 Topics: 1-Methyl-4-phenylpyridinium; Aminosalicylic Acid; Animals; Antitubercular Agents; Ciprofloxacin; HEK293 Cells; Humans; Inhibitory Concentration 50; Ion Transport; Kinetics; Levofloxacin; Linezolid; Metformin; Octamer Transcription Factor-1; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; Organic Cation Transport Proteins; Organic Cation Transporter 2; Pyrazinamide; Rifabutin; Rifampin; Zidovudine	2016
Metformin Adjunctive Therapy Does Not Improve the Sterilizing Activity of the First-Line Antitubercular Regimen in Mice. Antimicrobial agents and chemotherapy, 2017, Volume: 61, Issue:8 Topics: Animals; Antitubercular Agents; Bacterial Load; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Female; Isoniazid; Lung; Metformin; Mice; Mice, Inbred BALB C; Mycobacterium tuberculosis; Pyrazinamide; Recurrence; Rifampin; Tuberculosis, Pulmonary	2017
Short Communication - Synthesis of drug metal complexes and their influence on human platelet aggregation. Pakistan journal of pharmaceutical sciences, 2018, Volume: 31, Issue:2 Topics: Coordination Complexes; Drug Evaluation, Preclinical; Fluconazole; Humans; Isoniazid; Losartan; Metformin; Platelet Aggregation; Platelet Aggregation Inhibitors; Pyrazinamide	2018
Metformin induced autophagy in diabetes mellitus - Tuberculosis co-infection patients: A case study. The Indian journal of tuberculosis, 2019, Volume: 66, Issue:1 Topics: Adult; Antitubercular Agents; Autophagy; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Ethambutol; Humans; Hypoglycemic Agents; Insulin; Interferon-gamma; Interleukin-10; Isoniazid; Leukocytes, Mononuclear; Metformin; Microtubule-Associated Proteins; Middle Aged; Pyrazinamide; Rifampin; Sputum; Superoxide Dismutase; Tuberculosis	2019
Urinary excretion of metformin in diabetic patients with and without tuberculosis. The Indian journal of tuberculosis, 2023, Volume: 70, Issue:1 Topics: Antitubercular Agents; Diabetes Mellitus; Humans; India; Isoniazid; Metformin; Pyrazinamide; Tuberculosis	2023