metformin and propranolol

metformin has been researched along with propranolol in 35 studies

Research

Studies (35)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (2.86)	18.2507
2000's	8 (22.86)	29.6817
2010's	18 (51.43)	24.3611
2020's	8 (22.86)	2.80

Authors

Authors	Studies
Artursson, P; Bergström, CA; Matsson, P; Nagahara, N; Norinder, U; Tavelin, S	1
Lombardo, F; Obach, RS; Waters, NJ	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Campillo, NE; Guerra, A; Páez, JA	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Glen, RC; Lowe, R; Mitchell, JB	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A	1
Ahlin, G; Bergström, F; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Rehngren, M; Wan, H	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Miao, GX; Wang, YD; Yan, ZW; Zhang, LY	1
Peuler, JD	1
Goldberg, RA; Lee, S; McCann, JD; Tsirbas, A	1
Bachmakov, I; Endress, B; Fromm, MF; Glaeser, H; König, J; Mörl, F	1
Briese, V; Richter, C; Richter, DU; Szewczyk, M	1
Børsheim, E; Diaz, EC; Herndon, DN; Porter, C; Sidossis, LS; Suman, OE	1
Blagosklonny, MV	1
Bosch, J; Erice, E; García-Calderó, H; García-Pagán, JC; Gracia-Sancho, J; Lafoz, E; Sarin, SK; Tripathi, DM	1
André, N; Baglioni, M; Bondarenko, M; Carré, M; Laluce, NC; Menacho Márquez, M; Rico, M; Rozados, V; Scharovsky, OG	1
Kapoor, Y; Kumar, A; Sharma, R	1
Gus, EI; Jeschke, MG; Shahrokhi, S	1
Anselmino, LE; Baglioni, MV; Etichetti, CB; Girardini, J; Laluce, NC; Malizia, F; Marignac, VLM; Menacho Márquez, M; Rico, MJ; Rozados, V; Scharovsky, OG	1
Auger, C; Jeschke, MG; Knuth, CM	1
Ahmed, HMS; Ibrahim, IAAE; Ibrahim, WS; Mahmoud, AAA; Mahmoud, MF	1
Anghel, R; Forsea, L; Gales, L; Georgescu, M; Mitrea, D; Mitrica, R; Serbanescu, L; Stanculescu, I; Stefanica, I; Trifanescu, O	1
Cavalcanti, JVFL; da Motta Sobrinho, MA; de Araújo, CMB; Del Carmen Pinto Osorio, D; do Nascimento, BF; Dotto, GL; Silva, LFO	1

Reviews

6 review(s) available for metformin and propranolol

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Effects of pharmacological interventions on muscle protein synthesis and breakdown in recovery from burns. Burns : journal of the International Society for Burn Injuries, 2015, Volume: 41, Issue:4 Topics: Adrenergic beta-Antagonists; Anabolic Agents; Androgens; Body Surface Area; Burns; Human Growth Hormone; Humans; Hypoglycemic Agents; Insulin; Metformin; Muscle Proteins; Muscle, Skeletal; Oxandrolone; Propranolol; Recombinant Proteins; Testosterone; Treatment Outcome	2015
Koschei the immortal and anti-aging drugs. Cell death & disease, 2014, Dec-04, Volume: 5 Topics: Aging; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Caloric Restriction; Exercise; Folklore; Gene Expression; Glucose; Humans; Insulin Resistance; Longevity; Metformin; Propranolol; Russia; Sirolimus; TOR Serine-Threonine Kinases	2014
Anabolic and anticatabolic agents used in burn care: What is known and what is yet to be learned. Burns : journal of the International Society for Burn Injuries, 2020, Volume: 46, Issue:1 Topics: Anabolic Agents; Burns; Clonidine; Growth Hormone-Releasing Hormone; Hormones; Human Growth Hormone; Humans; Hypoglycemic Agents; Inflammation; Insulin; Insulin-Like Growth Factor Binding Protein 3; Insulin-Like Growth Factor I; Metformin; Oxandrolone; Propranolol; Testosterone; Thyroid Hormones	2020
Burn-induced hypermetabolism and skeletal muscle dysfunction. American journal of physiology. Cell physiology, 2021, 07-01, Volume: 321, Issue:1 Topics: Burns; Cachexia; Epigenesis, Genetic; Exercise; Human Growth Hormone; Humans; Insulin; Metformin; Muscle Proteins; Muscle, Skeletal; Muscular Atrophy; Oxandrolone; Propranolol; Protein Biosynthesis; Proteolysis; Sepsis; Signal Transduction; Wound Healing	2021
Antidiabetics, Anthelmintics, Statins, and Beta-Blockers as Co-Adjuvant Drugs in Cancer Therapy. Medicina (Kaunas, Lithuania), 2022, Sep-07, Volume: 58, Issue:9 Topics: Adenosine Monophosphate; Adrenergic beta-Antagonists; Anthelmintics; Anti-Bacterial Agents; Antihypertensive Agents; Antimalarials; Antineoplastic Agents; Atorvastatin; Breast Neoplasms; Cholesterol; Diabetes Mellitus, Type 2; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemic Agents; Male; Mebendazole; Metformin; Mevalonic Acid; Propranolol; Protein Kinases; Proto-Oncogene Proteins B-raf; Receptors, Adrenergic, beta-2; Tyrosine	2022

Other Studies

29 other study(ies) available for metformin and propranolol

Article	Year
Exploring the role of different drug transport routes in permeability screening. Journal of medicinal chemistry, 2005, Jan-27, Volume: 48, Issue:2 Topics: Administration, Oral; Biological Transport; Caco-2 Cells; Cell Line; Humans; Intestinal Absorption; Intestinal Mucosa; Intestine, Small; Membranes, Artificial; Models, Biological; Molecular Conformation; Monte Carlo Method; Permeability; Pharmaceutical Preparations; Pharmacokinetics	2005
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data. European journal of medicinal chemistry, 2009, Volume: 44, Issue:11 Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Neural computational prediction of oral drug absorption based on CODES 2D descriptors. European journal of medicinal chemistry, 2010, Volume: 45, Issue:3 Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
Predicting phospholipidosis using machine learning. Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5 Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Prediction of drug intestinal absorption by new linear and non-linear QSPR. European journal of medicinal chemistry, 2011, Volume: 46, Issue:1 Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics	2011
Measurement of unbound drug exposure in brain: modeling of pH partitioning explains diverging results between the brain slice and brain homogenate methods. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:3 Topics: Animals; Biological Transport; Brain; Chemical Phenomena; Dialysis; Hydrogen-Ion Concentration; In Vitro Techniques; Lysosomes; Male; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tissue Distribution	2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Synthesis, in vitro ADME profiling and in vivo pharmacological evaluation of novel glycogen phosphorylase inhibitors. Bioorganic & medicinal chemistry letters, 2020, 07-15, Volume: 30, Issue:14 Topics: Animals; Blood Glucose; Cell Proliferation; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epinephrine; Glycogen Phosphorylase; Hep G2 Cells; Hepatocytes; Humans; Hypoglycemic Agents; Indoles; Mice; Molecular Structure; Rats; Structure-Activity Relationship	2020
Opposing adrenergic actions of intravenous metformin on arterial pressure in female spontaneously hypertensive rats. Cardiovascular research, 1999, Volume: 43, Issue:1 Topics: Adrenergic beta-Antagonists; Animals; Blood Pressure; Chlorisondamine; Female; Ganglionic Blockers; Heart Rate; Hypoglycemic Agents; Injections, Intravenous; Metformin; Norepinephrine; Phenylephrine; Propranolol; Rats; Rats, Inbred SHR	1999
Thiazolidinedione induced thyroid associated orbitopathy. BMC ophthalmology, 2007, Apr-26, Volume: 7 Topics: Diplopia; Disease Progression; Drug Therapy, Combination; Exophthalmos; Female; Graves Ophthalmopathy; Humans; Hypoglycemic Agents; Magnetic Resonance Imaging; Metformin; Middle Aged; Propranolol; Propylthiouracil; Retreatment; Rosiglitazone; Thiazolidinediones	2007
Interaction of beta-blockers with the renal uptake transporter OCT2. Diabetes, obesity & metabolism, 2009, Volume: 11, Issue:11 Topics: Adrenergic beta-Antagonists; Biological Transport; Bisoprolol; Carbazoles; Carvedilol; Cell Line; Humans; Kidney; Metformin; Metoprolol; Organic Cation Transport Proteins; Organic Cation Transporter 2; Propanolamines; Propranolol	2009
A retrospective in vitro study of the impact of anti-diabetics and cardioselective pharmaceuticals on breast cancer. Anticancer research, 2012, Volume: 32, Issue:5 Topics: Adrenergic beta-1 Receptor Antagonists; Bisoprolol; Blood Glucose; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Female; Humans; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hypertension; Hypoglycemic Agents; Metformin; Oxidative Stress; Propranolol; Retrospective Studies; Thiazolidinediones	2012
Metformin reduces hepatic resistance and portal pressure in cirrhotic rats. American journal of physiology. Gastrointestinal and liver physiology, 2015, Sep-01, Volume: 309, Issue:5 Topics: Animals; Blood Pressure; Hypertension, Portal; Liver; Liver Cirrhosis; Male; Metformin; Portal Vein; Propranolol; Rats; Rats, Sprague-Dawley; Rats, Wistar; Vascular Resistance	2015
Metformin and propranolol combination prevents cancer progression and metastasis in different breast cancer models. Oncotarget, 2017, Jan-10, Volume: 8, Issue:2 Topics: Animals; Antihypertensive Agents; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Disease Models, Animal; Drug Repositioning; Drug Synergism; Energy Metabolism; Female; Glycolysis; Humans; Hypoglycemic Agents; Inhibitory Concentration 50; Metformin; Mice; Organelle Biogenesis; Propranolol; Xenograft Model Antitumor Assays	2017
Repurposing of Existing Drugs for the Bacterial Infections: An In silico and In vitro Study. Infectious disorders drug targets, 2020, Volume: 20, Issue:2 Topics: Amitriptyline; Anti-Bacterial Agents; Computer Simulation; Drug Repositioning; Gram-Negative Bacteria; Gram-Positive Bacteria; Metformin; Microbial Sensitivity Tests; Propranolol	2020
Repositioning metformin and propranolol for colorectal and triple negative breast cancers treatment. Scientific reports, 2021, 04-14, Volume: 11, Issue:1 Topics: Animals; beta Catenin; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Chemotherapy, Adjuvant; Colorectal Neoplasms; Drug Repositioning; Drug Resistance, Neoplasm; Drug Therapy, Combination; Epithelial-Mesenchymal Transition; Female; Humans; Metformin; Mice; Mice, Nude; Propranolol; Transplantation, Heterologous; Triple Negative Breast Neoplasms	2021
Propranolol and low-dose isoproterenol ameliorate insulin resistance, enhance β-arrestin2 signaling, and reduce cardiac remodeling in high-fructose, high-fat diet-fed mice: Comparative study with metformin. Life sciences, 2021, Dec-01, Volume: 286 Topics: Animals; beta-Arrestin 2; Blood Glucose; Diet, High-Fat; Fructose; Glucose; Heart; Insulin; Insulin Resistance; Isoproterenol; Male; Metformin; Mice; Propranolol; Signal Transduction; Ventricular Remodeling	2021
Adsorption of chloroquine, propranolol, and metformin in aqueous solutions using magnetic graphene oxide nanocomposite. Environmental science and pollution research international, 2023, Volume: 30, Issue:36 Topics: Adsorption; Chloroquine; Graphite; Hydrogen-Ion Concentration; Kinetics; Magnetic Phenomena; Metformin; Nanocomposites; Pharmaceutical Preparations; Propranolol; Water; Water Pollutants, Chemical	2023