metformin and propofol

metformin has been researched along with propofol in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (27.27)29.6817
2010's7 (63.64)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Adachi, T; Hayashi, JI; Hirota, K; Kusunoki, M; Matsuo, Y; Nishi, K; Okamoto, A; Shoji, T; Sumi, C; Takenaga, K; Tanaka, H; Uba, T1
Finley, J1
Chen, Y; Liu, NH; Zhang, XB; Zhu, L1
Cai, M; Ge, J; Gu, T; Huang, Y; Liu, L; Liu, X; Song, J; Sun, J; Yao, L; Zhang, Y1

Reviews

1 review(s) available for metformin and propofol

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

10 other study(ies) available for metformin and propofol

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Propofol induces a metabolic switch to glycolysis and cell death in a mitochondrial electron transport chain-dependent manner.
    PloS one, 2018, Volume: 13, Issue:2

    Topics: Anesthetics, Intravenous; Animals; Caspases; Cell Death; Cell Line, Tumor; Dose-Response Relationship, Drug; Electron Transport; Glycolysis; HeLa Cells; Humans; Hypoglycemic Agents; Membrane Potential, Mitochondrial; Metformin; Mice; Mitochondria; Muscle Cells; Neurons; Oxygen Consumption; Propofol; Reactive Oxygen Species; Time Factors

2018
Cellular stress and AMPK links metformin and diverse compounds with accelerated emergence from anesthesia and potential recovery from disorders of consciousness.
    Medical hypotheses, 2019, Volume: 124

    Topics: AMP-Activated Protein Kinases; Anesthesia; Anesthesia Recovery Period; Anesthetics; Animals; Brain Mapping; Calcium; Cell Lineage; Cell Proliferation; Consciousness; Consciousness Disorders; Dexmedetomidine; Humans; Isoflurane; Ketamine; Learning; Long-Term Potentiation; Memory; Metformin; Midazolam; Models, Neurological; Nicotine; Propofol; Reactive Oxygen Species; Sevoflurane; Unconsciousness

2019
Metformin with propofol enhances the scavenging ability of free radicals and inhibits lipid peroxidation in mice.
    European review for medical and pharmacological sciences, 2019, Volume: 23, Issue:11

    Topics: Anesthesia; Anesthetics, Intravenous; Animals; Drug Synergism; Free Radical Scavengers; Free Radicals; Injections, Intraperitoneal; Lipid Peroxidation; Male; Metformin; Mice; Models, Animal; NF-E2-Related Factor 2; NF-kappa B; Oxidative Stress; Propofol

2019
Metformin Inhibits Propofol-Induced Apoptosis of Mouse Hippocampal Neurons HT-22 Through Downregulating Cav-1.
    Drug design, development and therapy, 2020, Volume: 14

    Topics: Animals; Apoptosis; Caveolin 1; Cell Line; Dose-Response Relationship, Drug; Hippocampus; Metformin; Mice; Neurons; Propofol; Structure-Activity Relationship

2020