Compounds > metformin

metformin and propofol

metformin has been researched along with propofol in 11 studies

Research

Studies (11)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	3 (27.27)	29.6817
2010's	7 (63.64)	24.3611
2020's	1 (9.09)	2.80

Authors

Authors	Studies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Lombardo, F; Obach, RS; Waters, NJ	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Adachi, T; Hayashi, JI; Hirota, K; Kusunoki, M; Matsuo, Y; Nishi, K; Okamoto, A; Shoji, T; Sumi, C; Takenaga, K; Tanaka, H; Uba, T	1
Finley, J	1
Chen, Y; Liu, NH; Zhang, XB; Zhu, L	1
Cai, M; Ge, J; Gu, T; Huang, Y; Liu, L; Liu, X; Song, J; Sun, J; Yao, L; Zhang, Y	1

Reviews

1 review(s) available for metformin and propofol

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Other Studies

10 other study(ies) available for metformin and propofol

Article	Year
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Propofol induces a metabolic switch to glycolysis and cell death in a mitochondrial electron transport chain-dependent manner. PloS one, 2018, Volume: 13, Issue:2 Topics: Anesthetics, Intravenous; Animals; Caspases; Cell Death; Cell Line, Tumor; Dose-Response Relationship, Drug; Electron Transport; Glycolysis; HeLa Cells; Humans; Hypoglycemic Agents; Membrane Potential, Mitochondrial; Metformin; Mice; Mitochondria; Muscle Cells; Neurons; Oxygen Consumption; Propofol; Reactive Oxygen Species; Time Factors	2018
Cellular stress and AMPK links metformin and diverse compounds with accelerated emergence from anesthesia and potential recovery from disorders of consciousness. Medical hypotheses, 2019, Volume: 124 Topics: AMP-Activated Protein Kinases; Anesthesia; Anesthesia Recovery Period; Anesthetics; Animals; Brain Mapping; Calcium; Cell Lineage; Cell Proliferation; Consciousness; Consciousness Disorders; Dexmedetomidine; Humans; Isoflurane; Ketamine; Learning; Long-Term Potentiation; Memory; Metformin; Midazolam; Models, Neurological; Nicotine; Propofol; Reactive Oxygen Species; Sevoflurane; Unconsciousness	2019
Metformin with propofol enhances the scavenging ability of free radicals and inhibits lipid peroxidation in mice. European review for medical and pharmacological sciences, 2019, Volume: 23, Issue:11 Topics: Anesthesia; Anesthetics, Intravenous; Animals; Drug Synergism; Free Radical Scavengers; Free Radicals; Injections, Intraperitoneal; Lipid Peroxidation; Male; Metformin; Mice; Models, Animal; NF-E2-Related Factor 2; NF-kappa B; Oxidative Stress; Propofol	2019
Metformin Inhibits Propofol-Induced Apoptosis of Mouse Hippocampal Neurons HT-22 Through Downregulating Cav-1. Drug design, development and therapy, 2020, Volume: 14 Topics: Animals; Apoptosis; Caveolin 1; Cell Line; Dose-Response Relationship, Drug; Hippocampus; Metformin; Mice; Neurons; Propofol; Structure-Activity Relationship	2020