Compounds > metformin

metformin and pp242

metformin has been researched along with pp242 in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (75.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Alain, T; Blouin, MJ; Larsson, O; Morita, M; Pollak, M; Sonenberg, N; Topisirovic, I1
Kisfalvi, K; Ni, Y; Rozengurt, E; Sinnett-Smith, J; Soares, HP1
Ebata, T; Ishiwata, T; Iwama, A; Iwasawa, S; Koide, S; Kurimoto, R; Sekine, I; Tada, Y; Takiguchi, Y; Tatsumi, K1
Gao, Z; Jin, Z; Sun, C; Yang, X1

Other Studies

4 other study(ies) available for metformin and pp242

ArticleYear
Distinct perturbation of the translatome by the antidiabetic drug metformin.
    Proceedings of the National Academy of Sciences of the United States of America, 2012, Jun-05, Volume: 109, Issue:23

    Topics: Analysis of Variance; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Humans; Indoles; Metformin; Microarray Analysis; Neoplasms; Protein Biosynthesis; Purines; Sirolimus; TOR Serine-Threonine Kinases

2012
Different patterns of Akt and ERK feedback activation in response to rapamycin, active-site mTOR inhibitors and metformin in pancreatic cancer cells.
    PloS one, 2013, Volume: 8, Issue:2

    Topics: Antibiotics, Antineoplastic; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cell Proliferation; Extracellular Signal-Regulated MAP Kinases; Feedback, Physiological; Gene Expression Regulation, Neoplastic; Humans; Hypoglycemic Agents; Indoles; Insulin; Metformin; Morpholines; Neurotensin; Pancreatic Neoplasms; Phosphorylation; Proto-Oncogene Proteins c-akt; Purines; Pyrimidines; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases

2013
Drug resistance originating from a TGF-β/FGF-2-driven epithelial-to-mesenchymal transition and its reversion in human lung adenocarcinoma cell lines harboring an EGFR mutation.
    International journal of oncology, 2016, Volume: 48, Issue:5

    Topics: Adenocarcinoma; Adenocarcinoma of Lung; Antineoplastic Agents; B7-H1 Antigen; Cell Line, Tumor; Cell Survival; Cisplatin; Dimethyl Sulfoxide; Drug Resistance, Neoplasm; Epithelial-Mesenchymal Transition; ErbB Receptors; Fibroblast Growth Factor 2; Gefitinib; Gene Expression Regulation, Neoplastic; Humans; Indoles; Lung Neoplasms; Metformin; Mutation; Purines; Quinazolines; Transforming Growth Factor beta

2016
Combination of mTOR inhibitor PP242 and AMPK activator metformin exerts enhanced inhibitory effects on colorectal carcinoma cells in vitro by blocking multiple kinase pathways.
    Journal of chemotherapy (Florence, Italy), 2023, Volume: 35, Issue:3

    Topics: AMP-Activated Protein Kinases; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Humans; Mechanistic Target of Rapamycin Complex 1; Mechanistic Target of Rapamycin Complex 2; Metformin; Phosphorylation; Proto-Oncogene Proteins c-akt; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases

2023