metformin has been researched along with phenylephrine in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (42.86) | 18.2507 |
| 2000's | 3 (21.43) | 29.6817 |
| 2010's | 3 (21.43) | 24.3611 |
| 2020's | 2 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chen, S; Stucki, JW; Ubl, JJ | 1 |
| Chatton, JY; Chen, S; Stucki, JW; Ubl, JJ | 1 |
| Chen, XL; Panek, K; Rembold, CM | 1 |
| Lee, JM; Peuler, JD | 1 |
| Peuler, JD | 1 |
| Lee, JM; Peuler, JD; Smith, JM | 1 |
| Chan, AY; Dyck, JR; Proud, CG; Soltys, CL; Young, ME | 1 |
| Balaraman, R; Majithiya, JB | 1 |
| Fowler, A; Galiñanes, M; Hassouna, A; Loubani, M; Matata, BM; Standen, NB | 1 |
| Choi, HC; Sung, JY | 1 |
| Hansen, P; Osman, I; Pichavaram, P; Pyla, R; Segar, L | 1 |
| Funamoto, M; Hasegawa, K; Katanasaka, Y; Katayama, A; Miyazaki, Y; Morimoto, T; Nurmila, S; Shimizu, K; Shimizu, S; Sunagawa, Y | 1 |
| Chakravarthi, S; Chellian, J; David, SR; Lai, PPN; Rajabalaya, R | 1 |
14 other study(ies) available for metformin and phenylephrine
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Anti-diabetic biguanides inhibit hormone-induced intracellular Ca2+ concentration oscillations in rat hepatocytes.
Topics: Animals; Biguanides; Bucladesine; Calcium; Chlorides; Colforsin; Cyclic AMP; Glucagon; Inositol 1,4,5-Trisphosphate; Insulin; Liver; Male; Manganese Compounds; Metformin; Phenformin; Phenylephrine; Rats; Rats, Wistar; Second Messenger Systems | 1994 |
A critical evaluation of in situ measurement of mitochondrial electrical potentials in single hepatocytes.
Topics: Adrenergic alpha-Agonists; Animals; Cytophotometry; Evaluation Studies as Topic; Fluorescent Dyes; Hypoglycemic Agents; Liver; Membrane Potentials; Metformin; Mitochondria, Liver; Models, Theoretical; Phenformin; Phenylephrine; Rats; Reproducibility of Results; Rhodamine 123; Rhodamines | 1996 |
Metformin relaxes rat tail artery by repolarization and resultant decreases in Ca2+ influx and intracellular [Ca2+].
Topics: Animals; Arteries; Calcium; Electrophysiology; Insulin; Intracellular Membranes; Male; Metformin; Osmolar Concentration; Phenylephrine; Rats; Rats, Sprague-Dawley; Tail | 1997 |
Acute vasorelaxant effects of metformin and attenuation by stimulation of sympathetic agonist release.
Topics: Adrenergic Agonists; Animals; Arginine Vasopressin; Arteries; Female; In Vitro Techniques; Metformin; Nerve Endings; Nifedipine; Nitroprusside; Norepinephrine; Oxidopamine; Phenylephrine; Rats; Rats, Sprague-Dawley; Serotonin; Sympathomimetics; Tail; Vasoconstriction; Vasodilation; Vasodilator Agents | 1999 |
Opposing adrenergic actions of intravenous metformin on arterial pressure in female spontaneously hypertensive rats.
Topics: Adrenergic beta-Antagonists; Animals; Blood Pressure; Chlorisondamine; Female; Ganglionic Blockers; Heart Rate; Hypoglycemic Agents; Injections, Intravenous; Metformin; Norepinephrine; Phenylephrine; Propranolol; Rats; Rats, Inbred SHR | 1999 |
4-Aminopyridine antagonizes the acute relaxant action of metformin on adrenergic contraction in the ventral tail artery of the rat.
Topics: 4-Aminopyridine; Animals; Arteries; Dose-Response Relationship, Drug; Female; Hypoglycemic Agents; In Vitro Techniques; Metformin; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Phenylephrine; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Sprague-Dawley; Tail; Vasoconstrictor Agents | 1999 |
Activation of AMP-activated protein kinase inhibits protein synthesis associated with hypertrophy in the cardiac myocyte.
Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Animals, Newborn; Antibiotics, Antineoplastic; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Elongation Factor 2 Kinase; Enzyme Activation; Green Fluorescent Proteins; Hypertrophy; Hypoglycemic Agents; Immunoblotting; Luminescent Proteins; Metformin; Microscopy, Fluorescence; Multienzyme Complexes; Myocytes, Cardiac; Phenylephrine; Phosphorylation; Protein Serine-Threonine Kinases; Rats; Ribonucleotides; Ribose; Ribosomal Protein S6; Ribosomal Protein S6 Kinases, 70-kDa; Sirolimus; Time Factors | 2004 |
Metformin reduces blood pressure and restores endothelial function in aorta of streptozotocin-induced diabetic rats.
Topics: 4-Aminopyridine; Acetylcholine; Animals; Aorta, Thoracic; Blood Pressure; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Drug Combinations; Endothelium, Vascular; Hypoglycemic Agents; In Vitro Techniques; Lipid Peroxidation; Male; Metformin; NG-Nitroarginine Methyl Ester; Oxidative Stress; Phenylephrine; Potassium Channel Blockers; Rats; Rats, Sprague-Dawley; Recovery of Function; Tetraethylammonium; Vasoconstriction; Vasodilation | 2006 |
Mitochondrial dysfunction as the cause of the failure to precondition the diabetic human myocardium.
Topics: Adenosine; Adrenergic alpha-Agonists; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diazoxide; Enzyme Activation; Glyburide; Heart Atria; Humans; Hypoglycemic Agents; In Vitro Techniques; Ischemic Preconditioning, Myocardial; Membrane Potentials; Metformin; Mitochondria, Heart; Myocardial Ischemia; p38 Mitogen-Activated Protein Kinases; Phenylephrine; Potassium Channels; Protein Kinase C; Reactive Oxygen Species; Tetradecanoylphorbol Acetate | 2006 |
Metformin-induced AMP-activated protein kinase activation regulates phenylephrine-mediated contraction of rat aorta.
Topics: Actins; AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Animals; Aorta; Blood Pressure; Enzyme Activation; Hypertension; Metformin; Muscle Contraction; Muscle, Smooth, Vascular; Myosin Light Chains; Phenylephrine; Phosphorylation; Protein Serine-Threonine Kinases; Rats; Vasoconstriction | 2012 |
Metformin exaggerates phenylephrine-induced AMPK phosphorylation independent of CaMKKβ and attenuates contractile response in endothelium-denuded rat aorta.
Topics: AMP-Activated Protein Kinases; Animals; Aorta, Thoracic; Calcium-Calmodulin-Dependent Protein Kinase Kinase; Dose-Response Relationship, Drug; Drug Synergism; Endothelium, Vascular; Male; Metformin; Organ Culture Techniques; Phenylephrine; Phosphorylation; Rats; Rats, Wistar; Vasoconstriction | 2014 |
Metformin suppresses phenylephrine-induced hypertrophic responses by inhibiting p300-HAT activity in cardiomyocytes.
Topics: Acetylation; Adrenergic alpha-1 Receptor Agonists; Animals; Cardiomegaly; Cells, Cultured; E1A-Associated p300 Protein; Heart Failure; Histone Acetyltransferases; Metformin; Myocytes, Cardiac; Phenylephrine; Rats, Sprague-Dawley | 2021 |
Influence of rutin and its combination with metformin on vascular functions in type 1 diabetes.
Topics: Acetylcholine; Animals; Blood Glucose; Cholesterol; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Endothelium, Vascular; Lipids; Male; Metformin; Phenylephrine; Rats; Rats, Sprague-Dawley; Rutin | 2023 |