metformin has been researched along with pemetrexed in 7 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (71.43) | 24.3611 |
| 2020's | 2 (28.57) | 2.80 |
| Authors | Studies |
|---|---|
| Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ | 1 |
| Cherian, C; Gangjee, A; Hales, E; Hou, Z; Matherly, LH; Mitchell-Ryan, S; Orr, S; Raghavan, S; Ravindra, MP; Wang, Y | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Feng, X; Li, T; Li, Y; Yi, E; Zhang, Y | 1 |
| Broggini, M; Caiola, E; Colombo, MP; Corsetto, PA; de Braud, F; Fabbri, A; Galli, G; Gallucci, R; Ganzinelli, M; Garassino, MC; Gavazzi, C; Hollander, L; Marabese, M; Moro, M; Pruneri, G; Rizzo, AM; Signorelli, D; Sozzi, G; Tamborini, E; Torri, V; Triulzi, T; Vandoni, G; Vernieri, C | 1 |
| Chang, GR; Chen, CM; Chen, W; Chong, KY; Cidem, A; Lin, CH; Staniczek, T; Tsai, YT; Wang, JL; Yen, CC | 1 |
| Chitikela, S; Gupta, Y; Jain, D; Khurana, S; Kumar, S; Malik, PS; Pushpam, D; Singh, V; Verma, S | 1 |
1 review(s) available for metformin and pemetrexed
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
2 trial(s) available for metformin and pemetrexed
| Article | Year |
|---|---|
Exploiting FAsting-mimicking Diet and MEtformin to Improve the Efficacy of Platinum-pemetrexed Chemotherapy in Advanced LKB1-inactivated Lung Adenocarcinoma: The FAME Trial.
Topics: Adenocarcinoma of Lung; Adolescent; Adult; Aged; AMP-Activated Protein Kinase Kinases; Antineoplastic Combined Chemotherapy Protocols; Diet Therapy; Fasting; Female; Humans; Lung Neoplasms; Male; Metformin; Middle Aged; Mutation; Neoplasm Staging; Pemetrexed; Platinum Compounds; Protein Serine-Threonine Kinases; Survival Analysis; Young Adult | 2019 |
A phase II study of metformin plus pemetrexed and carboplatin in patients with non-squamous non-small cell lung cancer (METALUNG).
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Non-Small-Cell Lung; Humans; Lung Neoplasms; Metformin; Pemetrexed | 2023 |
4 other study(ies) available for metformin and pemetrexed
| Article | Year |
|---|---|
Identification of potent Yes1 kinase inhibitors using a library screening approach.
Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship | 2013 |
Discovery of 5-substituted pyrrolo[2,3-d]pyrimidine antifolates as dual-acting inhibitors of glycinamide ribonucleotide formyltransferase and 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase in de novo purine nucleotide biosynthesis: implic
Topics: AMP-Activated Protein Kinases; Animals; Antineoplastic Agents; Apoptosis; Cell Proliferation; CHO Cells; Cricetulus; Dose-Response Relationship, Drug; Drug Discovery; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Folic Acid Antagonists; Humans; Hydroxymethyl and Formyl Transferases; KB Cells; Models, Molecular; Molecular Structure; Purine Nucleotides; Pyrimidines; Pyrroles; Structure-Activity Relationship | 2013 |
Metformin synergistic pemetrexed suppresses non-small-cell lung cancer cell proliferation and invasion in vitro.
Topics: Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Drug; Drug Synergism; Humans; Lung Neoplasms; Metformin; Pemetrexed | 2017 |
Benefits of Metformin Combined with Pemetrexed-Based Platinum Doublets as a First-Line Therapy for Advanced Lung Adenocarcinoma Patients with Diabetes.
Topics: Adenocarcinoma of Lung; Aged; Antineoplastic Combined Chemotherapy Protocols; Diabetes Complications; Diabetes Mellitus; Disease-Free Survival; Drug Therapy, Combination; Female; Humans; Kaplan-Meier Estimate; Lung Neoplasms; Male; Metformin; Middle Aged; Mutation; Pemetrexed; Platinum; Probability; Proportional Hazards Models; Retrospective Studies; Taiwan; Treatment Outcome | 2021 |