metformin has been researched along with olaparib in 4 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 2 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ | 1 |
| Al-Wahab, Z; Ali-Fehmi, R; Buekers, T; Chhina, J; Dar, S; Hijaz, M; Mert, I; Munkarah, AR; Rattan, R; Taylor, M | 1 |
| Gajek, A; Gralewska, P; Marczak, A; Rogalska, A | 1 |
| Chi, BJ; Quan, LL; Sun, Y; Wang, SQ; Wei, B; Zhao, JT | 1 |
4 other study(ies) available for metformin and olaparib
| Article | Year |
|---|---|
Identification of potent Yes1 kinase inhibitors using a library screening approach.
Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship | 2013 |
Preclinical evaluation of olaparib and metformin combination in BRCA1 wildtype ovarian cancer.
Topics: AMP-Activated Protein Kinases; Animals; Antineoplastic Combined Chemotherapy Protocols; BRCA1 Protein; Carcinoma, Ovarian Epithelial; Cell Growth Processes; Cell Line, Tumor; Cisplatin; Drug Screening Assays, Antitumor; Female; Genes, BRCA1; Humans; Metformin; Mice; Mice, Nude; Neoplasms, Glandular and Epithelial; Ovarian Neoplasms; Phthalazines; Piperazines; Poly(ADP-ribose) Polymerase Inhibitors; Xenograft Model Antitumor Assays | 2016 |
Metformin Affects Olaparib Sensitivity through Induction of Apoptosis in Epithelial Ovarian Cancer Cell Lines.
Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Ovarian Epithelial; Caspase 3; Caspase 7; Cell Line, Tumor; DNA Damage; Drug Synergism; Female; Humans; Hypoglycemic Agents; Membrane Potential, Mitochondrial; Metformin; Ovarian Neoplasms; Phosphatidylserines; Phthalazines; Piperazines; Reactive Oxygen Species | 2021 |
Metformin Can Enhance the Inhibitory Effect of Olaparib in Bladder Cancer Cells.
Topics: Cell Line, Tumor; Cell Proliferation; Humans; Metformin; Phthalazines; Piperazines; Proto-Oncogene Proteins c-myc; Signal Transduction; Urinary Bladder Neoplasms | 2022 |