metformin and neuropeptide y

metformin has been researched along with neuropeptide y in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (12.50)18.2507
2000's2 (25.00)29.6817
2010's4 (50.00)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Huupponen, R; Jhanwar-Uniyal, M; Koulu, M; Pesonen, U; Rouru, J; Rouvari, T; Santti, E; Virtanen, K1
Chau-Van, C; Gaillard, RC; Gamba, M; Pralong, FP; Salvi, R1
Campagna, G; De Marinis, L; Guido, M; Lanzone, A; Proto, C; Romualdi, D1
Aubert, G; Mansuy, V; Pellerin, L; Pralong, FP; Voirol, MJ1
Cao, CX; Gao, YY; Li, L; Lv, WS; Sun, RX; Wang, J; Wang, YL; Wen, JP; Xian, YX1
Belsham, DD; Ramos, EH; Wong, BC; Ye, W1
Bakhtyukov, A; Bayunova, L; Derkach, K; Romanova, I; Shpakov, A; Zakharova, I; Zorina, I1
Fliers, E; Hol, EM; Huitinga, I; Kalsbeek, A; Kalsbeek, MJ; Korpel, NL; la Fleur, SE; Romijn, JA; Swaab, DF; Wolff, SE; Yi, CX1

Trials

1 trial(s) available for metformin and neuropeptide y

ArticleYear
Alteration of ghrelin-neuropeptide Y network in obese patients with polycystic ovary syndrome: role of hyperinsulinism.
    Clinical endocrinology, 2008, Volume: 69, Issue:4

    Topics: Adult; Female; Ghrelin; Glucose Tolerance Test; Humans; Hyperinsulinism; Hypoglycemic Agents; Insulin; Leptin; Metformin; Neuropeptide Y; Obesity; Pilot Projects; Polycystic Ovary Syndrome; Signal Transduction; Young Adult

2008

Other Studies

7 other study(ies) available for metformin and neuropeptide y

ArticleYear
Anorectic effect of metformin in obese Zucker rats: lack of evidence for the involvement of neuropeptide Y.
    European journal of pharmacology, 1995, Jan-24, Volume: 273, Issue:1-2

    Topics: Administration, Oral; Animals; Appetite Depressants; Blood Glucose; Body Weight; Drinking; Eating; Hypothalamus; Injections, Subcutaneous; Insulin; Male; Metformin; Neuropeptide Y; Obesity; Rats; Rats, Zucker; RNA, Messenger

1995
Metformin inhibits adenosine 5'-monophosphate-activated kinase activation and prevents increases in neuropeptide Y expression in cultured hypothalamic neurons.
    Endocrinology, 2007, Volume: 148, Issue:2

    Topics: AMP-Activated Protein Kinases; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Activation; Gene Expression; Glucose; Hypoglycemic Agents; Hypothalamus; Metformin; Multienzyme Complexes; Neurons; Neuropeptide Y; Osmolar Concentration; Phosphorylation; Pro-Opiomelanocortin; Protein Serine-Threonine Kinases; Rats

2007
The anorexigenic effects of metformin involve increases in hypothalamic leptin receptor expression.
    Metabolism: clinical and experimental, 2011, Volume: 60, Issue:3

    Topics: Agouti-Related Protein; Animals; Blood Glucose; Body Weight; Eating; Humans; Hypoglycemic Agents; Hypothalamus; Insulin; Leptin; Male; Metformin; Neuropeptide Y; Obesity; Pro-Opiomelanocortin; Random Allocation; Rats; Rats, Long-Evans; Receptors, Leptin; Reverse Transcriptase Polymerase Chain Reaction; RNA; Statistics, Nonparametric

2011
The effect of metformin on food intake and its potential role in hypothalamic regulation in obese diabetic rats.
    Brain research, 2012, Mar-20, Volume: 1444

    Topics: Administration, Oral; Agouti-Related Protein; AMP-Activated Protein Kinases; Animals; Blood Glucose; Chromatography, Liquid; Diabetes Mellitus, Experimental; Disease Models, Animal; Eating; Gene Expression Regulation; Hypoglycemic Agents; Hypothalamus; Male; Metformin; Neuropeptide Y; Phosphorylation; Pro-Opiomelanocortin; Rats; Rats, Sprague-Dawley; RNA, Messenger; Signal Transduction; STAT3 Transcription Factor; Tandem Mass Spectrometry

2012
Beneficial Effects of Metformin and/or Salicylate on Palmitate- or TNFα-Induced Neuroinflammatory Marker and Neuropeptide Gene Regulation in Immortalized NPY/AgRP Neurons.
    PloS one, 2016, Volume: 11, Issue:11

    Topics: Agouti-Related Protein; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; Cells, Cultured; Embryo, Mammalian; Female; Gene Expression Regulation; Hypoglycemic Agents; Hypothalamus; Inflammation; Male; Metformin; Mice; Mice, Inbred BALB C; Neurons; Neuropeptide Y; Palmitates; Phosphorylation; Salicylates; Tumor Necrosis Factor-alpha

2016
The evidence of metabolic-improving effect of metformin in Ay/a mice with genetically-induced melanocortin obesity and the contribution of hypothalamic mechanisms to this effect.
    PloS one, 2019, Volume: 14, Issue:3

    Topics: Agouti-Related Protein; Animals; Body Weight; Female; Gene Expression Regulation; Hypoglycemic Agents; Hypothalamus; Leptin; Melanocortins; Metformin; Mice; Mice, Inbred C57BL; Mice, Obese; Neuropeptide Y; Obesity; Receptors, Leptin

2019
The impact of antidiabetic treatment on human hypothalamic infundibular neurons and microglia.
    JCI insight, 2020, 08-20, Volume: 5, Issue:16

    Topics: Aged; Aged, 80 and over; Case-Control Studies; Diabetes Mellitus, Type 2; Female; Humans; Hypoglycemic Agents; Insulin; Male; Membrane Proteins; Metformin; Microglia; Neurons; Neuropeptide Y; Pituitary Gland; Pro-Opiomelanocortin

2020