metformin and nad

metformin has been researched along with nad in 21 studies

Research

Studies (21)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (4.76)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	11 (52.38)	24.3611
2020's	9 (42.86)	2.80

Authors

Authors	Studies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Bailey, CJ; Wollen, N	1
Balen, AH; Harris, SE; Maruthini, D; Picton, HM; Tang, T	1
Albini, A; Bertolini, F; Calleri, A; Dallaglio, K; Gregato, G; Labanca, V; Mancuso, P; Noonan, DM; Orecchioni, S; Reggiani, F; Rossi, T; Talarico, G	1
Bush, LN; Davidson, SM; Freinkman, E; Gitego, N; Gui, DY; Hosios, AM; Luengo, A; Sullivan, LB; Thomas, CJ; Vander Heiden, MG	1
Niedernhofer, LJ; Robbins, PD	1
Bobbili, DR; Brockmann, K; Bus, C; Carvajal Berrio, DA; Fitzgerald, JC; Gasser, T; Glaab, E; Hauser, AK; Krüger, R; Kübler, M; Lewin, R; Madlung, J; Martins, LM; Maurer, B; May, P; Nordheim, A; Picard, D; Riess, O; Schenke-Layland, K; Schindler, KM; Schulte, C; Schwarz, LM; Sharma, M; Vartholomaiou, E; Wüst, R; Zimprich, A	1
Chen, K; Feng, T; Ling, S; Liu, J; Liu, P; Shan, Q; Song, P; Xiang, P; Xie, H; Xu, X; Zhang, X; Zheng, S; Zhou, L	1
Klimova, B; Kuca, K; Novotny, M	1
Benjamin, D; Colombi, M; El-Shemerly, MY; Hall, MN; Hindupur, SK; Lane, HA; Maira, SM; Moroni, C; Pohlmann, J; Robay, D	1
Agius, L; Alshawi, A	1
Banerjee, A; Beers, SA; Birts, CN; Blaydes, JP; Cutress, RI; Darley, M; Mirnezami, AH; Parker, R; Rose-Zerilli, MJJ; West, J	1
Ansari, IH; Longacre, MJ; MacDonald, MJ; Stoker, SW	1
Barry, AP; Bonglack, EN; Cable, JM; Ch'ng, J; Christofk, HR; Dave, SS; Luftig, MA; Messinger, JE; Parnell, KM; Reinoso-Vizcaíno, NM; Russell, VS	1
Al-Dhabi, NA; Arasu, MV; Arockiaraj, J; C, M; Chatterjee, S; Choi, KC; Karuppiah, K; Natarajan, S; Raj, V; Ramanujam, GM; Ramasamy, M	1
Bharti, S; Bhujwalla, Z; Gabrielson, E; Tully, E; Woo, J	1
Abiko, Y; Kobayashi, Y; Liu, S; Otani, H; Sasaki, S; Sato, S; Shinohara, Y; Takahashi, N; Wang, X; Washio, J	1
Chen, L; Chen, R; Cheng, L; Chi, W; Deepak, RNVK; Fan, H; Guo, Z; Huang, Y; Liang, Y; Liao, Y; Lin, JD; Meng, Z; Tao, L; Wang, G; Wang, W; Wang, Y; Xie, M; Yang, M; Zhang, J; Zhang, Y	1
Annane, D; Baron, L; Baulande, S; Bègue, AL; Cañeque, T; Cougoule, C; Dawson, MA; Dingli, F; Durand, S; Emam, L; Gaillet, C; Gandon, V; Gestraud, P; Kroemer, G; Loew, D; Manel, N; Mansart, A; Meunier, E; Müller, S; Näser, E; Pantoș, GD; Péricat, D; Puisieux, A; Robil, C; Rodriguez, R; Salmon, H; Sencio, V; Servant, N; Sindikubwabo, F; Solier, S; Trottein, F; Versini, A; Watson, S; Wu, TD	1
Baur, JA; de Cabo, R; Espinoza, SE; Khosla, S; Musi, N	1
Beckers, J; Birkenfeld, AL; Goj, T; Gudiksen, A; Hrabě de Angelis, M; Irmler, M; Karstoft, K; Lehmann, R; Li, Q; Maurer, J; Peter, A; Pilegaard, H; Pilmark, NS; Weigert, C; Xu, G; Zhao, X	1

Reviews

1 review(s) available for metformin and nad

Article	Year
Anti-Aging Drugs - Prospect of Longer Life? Current medicinal chemistry, 2018, Volume: 25, Issue:17 Topics: Animals; Humans; Longevity; Metformin; NAD; Quality of Life; Resveratrol; Sirolimus; Stilbenes	2018

Other Studies

20 other study(ies) available for metformin and nad

Article	Year
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Inhibition of hepatic gluconeogenesis by metformin. Synergism with insulin. Biochemical pharmacology, 1988, Nov-15, Volume: 37, Issue:22 Topics: Adenosine Triphosphate; Alanine; Animals; Drug Synergism; Gluconeogenesis; Insulin; Liver; Male; Metformin; NAD; Rats; Rats, Inbred Strains	1988
Metabolism and karyotype analysis of oocytes from patients with polycystic ovary syndrome. Human reproduction (Oxford, England), 2010, Volume: 25, Issue:9 Topics: Adult; Carbohydrate Metabolism; Cell Differentiation; Cells, Cultured; Chromosome Aberrations; Chromosome Segregation; Chromosomes, Human, 21-22 and Y; Female; Humans; Hypoglycemic Agents; Meiosis; Metformin; Mitochondria; NAD; NADP; Oocytes; Ovarian Cysts; Ovulation Induction; Polycystic Ovary Syndrome; Spectral Karyotyping; Sperm Injections, Intracytoplasmic; Young Adult	2010
Aspirin and atenolol enhance metformin activity against breast cancer by targeting both neoplastic and microenvironment cells. Scientific reports, 2016, Jan-05, Volume: 6 Topics: Adipose Tissue, White; AMP-Activated Protein Kinases; Animals; Antineoplastic Agents; Apoptosis; Aspirin; Atenolol; Biomarkers, Tumor; Breast Neoplasms; Cell Line, Tumor; Disease Models, Animal; Drug Synergism; Electron Transport Complex I; Female; Humans; Metformin; NAD; Neoplasm Metastasis; Stem Cells; Triple Negative Breast Neoplasms; Tumor Burden; Tumor Microenvironment; Xenograft Model Antitumor Assays	2016
Environment Dictates Dependence on Mitochondrial Complex I for NAD+ and Aspartate Production and Determines Cancer Cell Sensitivity to Metformin. Cell metabolism, 2016, 11-08, Volume: 24, Issue:5 Topics: Animals; Aspartic Acid; Cell Line, Tumor; Cell Proliferation; Electron Transport Complex I; Homeostasis; Humans; Metformin; Mice, Nude; Mitochondria; NAD; Neoplasms; Pyruvic Acid; Tumor Microenvironment	2016
Advances in Therapeutic Approaches to Extend Healthspan: a perspective from the 2 Aging cell, 2017, Volume: 16, Issue:4 Topics: Animals; Cellular Senescence; Drug Evaluation, Preclinical; Free Radical Scavengers; Healthy Lifestyle; Humans; Longevity; Metformin; Models, Animal; NAD; Sirolimus; Stem Cell Factor; Stem Cell Transplantation; Stem Cells	2017
Metformin reverses TRAP1 mutation-associated alterations in mitochondrial function in Parkinson's disease. Brain : a journal of neurology, 2017, Sep-01, Volume: 140, Issue:9 Topics: Adenosine Triphosphate; Apoptosis; Case-Control Studies; Cells, Cultured; Fibroblasts; High-Temperature Requirement A Serine Peptidase 2; HSP90 Heat-Shock Proteins; Humans; Membrane Potential, Mitochondrial; Metformin; Mitochondria; Mitochondrial Proteins; Mutation; NAD; Organelle Biogenesis; Oxygen Consumption; Parkinson Disease; Protein Kinases; Reactive Oxygen Species; Serine Endopeptidases	2017
Metformin ameliorates arsenic trioxide hepatotoxicity via inhibiting mitochondrial complex I. Cell death & disease, 2017, 11-02, Volume: 8, Issue:11 Topics: Animals; Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Cell Line; Chemical and Drug Induced Liver Injury; Electron Transport Complex I; Glucose; Glycolysis; Humans; Leukemia, Myeloid; Male; Metformin; Mice; NAD; Oxidative Phosphorylation; Oxides; Reactive Oxygen Species; Rotenone	2017
Dual Inhibition of the Lactate Transporters MCT1 and MCT4 Is Synthetic Lethal with Metformin due to NAD+ Depletion in Cancer Cells. Cell reports, 2018, 12-11, Volume: 25, Issue:11 Topics: Acids; Animals; Cell Line, Tumor; Energy Metabolism; Humans; Intracellular Space; Lactic Acid; Male; Metformin; Mice, Inbred C57BL; Monocarboxylic Acid Transporters; Muscle Proteins; NAD; Neoplasms; Reserpine; Symporters; Synthetic Lethal Mutations	2018
Low metformin causes a more oxidized mitochondrial NADH/NAD redox state in hepatocytes and inhibits gluconeogenesis by a redox-independent mechanism. The Journal of biological chemistry, 2019, 02-22, Volume: 294, Issue:8 Topics: Animals; Aspartic Acid; Cells, Cultured; Fructose-Bisphosphatase; Gluconeogenesis; Glucose; Glycolysis; Hepatocytes; Hypoglycemic Agents; Lactic Acid; Malates; Male; Metformin; Mice; Mice, Inbred C57BL; Mitochondria, Liver; NAD; Oxidation-Reduction; Phosphofructokinase-1; Rats; Rats, Wistar	2019
Stem cell-like breast cancer cells with acquired resistance to metformin are sensitive to inhibitors of NADH-dependent CtBP dimerization. Carcinogenesis, 2019, 07-20, Volume: 40, Issue:7 Topics: Alcohol Oxidoreductases; Animals; Antineoplastic Agents, Alkylating; Cell Line, Tumor; DNA-Binding Proteins; Drug Resistance, Neoplasm; Epithelial-Mesenchymal Transition; Female; Glycolysis; Humans; Inhibitory Concentration 50; Metabolic Networks and Pathways; Metformin; Mice; NAD; Neoplastic Stem Cells; Protein Multimerization; Sequence Analysis, RNA; Single-Cell Analysis; Spheroids, Cellular; Tenascin; Triple Negative Breast Neoplasms; Xenograft Model Antitumor Assays	2019
Metformin's Therapeutic Efficacy in the Treatment of Diabetes Does Not Involve Inhibition of Mitochondrial Glycerol Phosphate Dehydrogenase. Diabetes, 2021, Volume: 70, Issue:7 Topics: Animals; Diabetes Mellitus, Type 2; Gluconeogenesis; Glycerolphosphate Dehydrogenase; Humans; Male; Metformin; Mice; Mice, Inbred BALB C; Mitochondria; NAD; Oxidation-Reduction; Phenformin; Rats	2021
Monocarboxylate transporter antagonism reveals metabolic vulnerabilities of viral-driven lymphomas. Proceedings of the National Academy of Sciences of the United States of America, 2021, 06-22, Volume: 118, Issue:25 Topics: B-Lymphocytes; Cell Line, Tumor; Cell Proliferation; Epstein-Barr Virus Infections; Glucose; Glutathione; Herpesvirus 4, Human; Herpesvirus 8, Human; Humans; Lactic Acid; Lymphoma; Metformin; Monocarboxylic Acid Transporters; NAD; Oxygen Consumption; Phenformin; Reactive Oxygen Species; Up-Regulation	2021
Cholecalciferol and metformin protect against lipopolysaccharide-induced endothelial dysfunction and senescence by modulating sirtuin-1 and protein arginine methyltransferase-1. European journal of pharmacology, 2021, Dec-05, Volume: 912 Topics: Antioxidants; Arginine; Cell Cycle Checkpoints; Cell Line; Cellular Senescence; Cholecalciferol; Endothelium; Homocysteine; Humans; Lipopolysaccharides; Metformin; Methylation; NAD; Nitric Oxide; Protective Agents; Protein-Arginine N-Methyltransferases; Repressor Proteins; S-Adenosylmethionine; Sirtuin 1; Telomerase; Vitamin D Response Element	2021
Biguanide drugs enhance cytotoxic effects of cisplatin by depleting aspartate and NAD+ in sensitive cancer cells. Cancer biology & therapy, 2021, 12-02, Volume: 22, Issue:10-12 Topics: Antineoplastic Agents; Aspartic Acid; Cisplatin; Metformin; NAD; Neoplasms; Pharmaceutical Preparations	2021
Rewired Cellular Metabolic Profiles in Response to Metformin under Different Oxygen and Nutrient Conditions. International journal of molecular sciences, 2022, Jan-17, Volume: 23, Issue:2 Topics: Cell Line, Tumor; Cell Proliferation; Culture Media; Glucose; Glutamine; HeLa Cells; Humans; Lactic Acid; Metabolomics; Metformin; NAD; Oxygen; Pyruvic Acid; Tumor Hypoxia	2022
Hepatic mitochondrial NAD + transporter SLC25A47 activates AMPKα mediating lipid metabolism and tumorigenesis. Hepatology (Baltimore, Md.), 2023, Dec-01, Volume: 78, Issue:6 Topics: AMP-Activated Protein Kinases; Animals; Carcinogenesis; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Cholesterol; Fatty Acids; Humans; Lipid Metabolism; Liver; Liver Neoplasms; Mammals; Metformin; Mice; NAD	2023
A druggable copper-signalling pathway that drives inflammation. Nature, 2023, Volume: 617, Issue:7960 Topics: Animals; Cell Plasticity; Copper; Epigenesis, Genetic; Hydrogen Peroxide; Inflammation; Macrophage Activation; Macrophages; Metformin; Mice; Mitochondria; NAD; Oxidation-Reduction; Signal Transduction	2023
Drugs Targeting Mechanisms of Aging to Delay Age-Related Disease and Promote Healthspan: Proceedings of a National Institute on Aging Workshop. The journals of gerontology. Series A, Biological sciences and medical sciences, 2023, Jun-16, Volume: 78, Issue:Supplement Topics: Aging; Humans; Metformin; NAD; National Institute on Aging (U.S.); Senotherapeutics; United States	2023
Redox state and altered pyruvate metabolism contribute to a dose-dependent metformin-induced lactate production of human myotubes. American journal of physiology. Cell physiology, 2023, 10-01, Volume: 325, Issue:4 Topics: Humans; Lactate Dehydrogenases; Lactic Acid; Metformin; Muscle Fibers, Skeletal; NAD; Oxidation-Reduction; Oxidoreductases; Pyruvates	2023