metformin has been researched along with metoprolol in 30 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (10.00) | 18.2507 |
| 2000's | 10 (33.33) | 29.6817 |
| 2010's | 15 (50.00) | 24.3611 |
| 2020's | 2 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Artursson, P; Bergström, CA; Matsson, P; Nagahara, N; Norinder, U; Tavelin, S | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Ahlin, G; Bergström, F; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Rehngren, M; Wan, H | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Landin, K; Smith, U; Tengborn, L | 2 |
| Herlitz, H; Landin, K; Widgren, B | 1 |
| Lynch, T | 1 |
| Anderson, KM; Bakris, GL; Bell, DS; Fonseca, V; Katholi, RE; Lukas, MA; McGill, JB; Messerli, FH; Phillips, RA; Raskin, P; Waterhouse, B; Wright, JT | 1 |
| Bachmakov, I; Endress, B; Fromm, MF; Glaeser, H; König, J; Mörl, F | 1 |
| Dolkart, O; Gigi, R; Katzburg, S; Salai, M; Somjen, D; Yakobson, O | 1 |
| Brandmayr, C; Kerber, H; Schramm, E; Winker, M | 1 |
| Han, M; Huang, J; Jin, YW; Ma, YR; Qin, HY; Rao, Z; Shi, AX; Wang, XD; Wang, YF; Wu, XA; Zhang, F; Zhang, GQ; Zhou, Y | 1 |
| Moermond, CT; Smit, CE | 1 |
| Chen, Z; Gongol, B; Lei, T; Li, Z; Marin, TL; Shang, F; Shyy, JY; Wang, Y; Xiao, H; Yin, Y; Zhang, J; Zhang, YY | 1 |
| Ma, YR; Qin, HY; Shi, AX; Wu, XA; Wu, YF; Zhang, GQ; Zhang, T | 1 |
| Duan, YQ; Ma, YR; Wu, XA; Wu, YF; Zhang, GQ | 1 |
| Glick, A; Johnson, C; Sista, V | 1 |
| Blahova, J; Doubkova, V; Faldyna, M; Hesova, R; Hodkovicova, N; Hollerova, A; Kotoucek, J; Lakdawala, P; Mares, J; Marsalek, P; Medkova, D; Svobodova, Z; Taştan, Y; Tichy, F | 1 |
1 review(s) available for metformin and metoprolol
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
4 trial(s) available for metformin and metoprolol
| Article | Year |
|---|---|
Effects of metformin and metoprolol CR on hormones and fibrinolytic variables during a hyperinsulinemic, euglycemic clamp in man.
Topics: Cross-Over Studies; Double-Blind Method; Fasting; Fatty Acids, Nonesterified; Fibrinolysis; Glucose Clamp Technique; Hormones; Humans; Insulin; Intestinal Absorption; Lipoprotein(a); Male; Metformin; Metoprolol; Middle Aged | 1994 |
Metformin and metoprolol CR treatment in non-obese men.
Topics: Analysis of Variance; Anthropometry; Blood Pressure; Body Weight; Delayed-Action Preparations; Double-Blind Method; Fibrinolysis; Glucose Clamp Technique; Humans; Hypertension; Insulin; Lipids; Male; Metformin; Metoprolol; Middle Aged | 1994 |
Relationship between sodium-lithium countertransport and insulin sensitivity in mild hypertension.
Topics: Antihypertensive Agents; Antiporters; Blood Glucose; Blood Pressure; Body Mass Index; Cross-Over Studies; Double-Blind Method; Erythrocytes; Glucose Clamp Technique; Humans; Hypertension; Insulin; Lithium; Male; Metformin; Metoprolol; Middle Aged; Sodium | 1996 |
Differential effect of beta-blocker therapy on insulin resistance as a function of insulin sensitizer use: results from GEMINI.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Blood Glucose; Carbazoles; Carvedilol; Diabetes Mellitus, Type 2; Female; Humans; Hypertension; Insulin Resistance; Male; Metformin; Metoprolol; Middle Aged; Propanolamines; Thiazolidinediones; Treatment Outcome | 2007 |
25 other study(ies) available for metformin and metoprolol
| Article | Year |
|---|---|
Exploring the role of different drug transport routes in permeability screening.
Topics: Administration, Oral; Biological Transport; Caco-2 Cells; Cell Line; Humans; Intestinal Absorption; Intestinal Mucosa; Intestine, Small; Membranes, Artificial; Models, Biological; Molecular Conformation; Monte Carlo Method; Permeability; Pharmaceutical Preparations; Pharmacokinetics | 2005 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Measurement of unbound drug exposure in brain: modeling of pH partitioning explains diverging results between the brain slice and brain homogenate methods.
Topics: Animals; Biological Transport; Brain; Chemical Phenomena; Dialysis; Hydrogen-Ion Concentration; In Vitro Techniques; Lysosomes; Male; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tissue Distribution | 2011 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Medication costs as a primary cause of nonadherence in the elderly.
Topics: Aged; Anticholesteremic Agents; Antihypertensive Agents; Atorvastatin; Coronary Disease; Costs and Cost Analysis; Diabetes Mellitus, Type 2; Drug Prescriptions; Drugs, Generic; Female; Heptanoic Acids; Humans; Hyperlipidemias; Hypertension; Hypoglycemic Agents; Metformin; Metoprolol; Patient Compliance; Pharmacists; Pyrroles; Self Administration | 2006 |
Interaction of beta-blockers with the renal uptake transporter OCT2.
Topics: Adrenergic beta-Antagonists; Biological Transport; Bisoprolol; Carbazoles; Carvedilol; Cell Line; Humans; Kidney; Metformin; Metoprolol; Organic Cation Transport Proteins; Organic Cation Transporter 2; Propanolamines; Propranolol | 2009 |
Effects of commonly used medications on bone tissue mineralisation in SaOS-2 human bone cell line: an in vitro study.
Topics: Adrenergic beta-1 Receptor Antagonists; Bone and Bones; Calcification, Physiologic; Cell Line; Cell Proliferation; Citalopram; Fluorobenzenes; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemic Agents; Metformin; Metoprolol; Omeprazole; Osteoblasts; Proton Pump Inhibitors; Pyrimidines; Rosuvastatin Calcium; Selective Serotonin Reuptake Inhibitors; Sulfonamides | 2013 |
Impact assessment of emission management strategies of the pharmaceuticals Metformin and Metoprolol to the aquatic environment using Bayesian networks.
Topics: Bayes Theorem; Environmental Monitoring; Metformin; Metoprolol; Models, Chemical; Risk Assessment; Waste Disposal, Fluid; Water Pollutants, Chemical; Water Pollution, Chemical | 2015 |
Simultaneous Determination of Metformin, Metoprolol and its Metabolites in Rat Plasma by LC-MS-MS: Application to Pharmacokinetic Interaction Study.
Topics: Adrenergic beta-Antagonists; Animals; Area Under Curve; Chromatography, Liquid; Hypoglycemic Agents; Limit of Detection; Male; Metformin; Metoprolol; Rats; Rats, Wistar; Reproducibility of Results; Tandem Mass Spectrometry | 2016 |
Derivation of water quality standards for carbamazepine, metoprolol, and metformin and comparison with monitoring data.
Topics: Carbamazepine; Ecosystem; Ecotoxicology; Environmental Monitoring; Metformin; Metoprolol; Toxicity Tests, Acute; Toxicity Tests, Chronic; Water Pollutants, Chemical; Water Quality | 2016 |
Cardiovascular Protective Effect of Metformin and Telmisartan: Reduction of PARP1 Activity via the AMPK-PARP1 Cascade.
Topics: AMP-Activated Protein Kinases; Animals; Benzimidazoles; Benzoates; Blotting, Western; Cardiotonic Agents; Cells, Cultured; Endothelium, Vascular; Glipizide; Humans; Male; MAP Kinase Signaling System; Metformin; Metoprolol; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Rats, Inbred SHR; Rats, Inbred WKY; Real-Time Polymerase Chain Reaction; Telmisartan | 2016 |
Metoprolol decreases the plasma exposure of metformin via the induction of liver, kidney and muscle uptake in rats.
Topics: Adrenergic beta-1 Receptor Antagonists; Animals; Drug Interactions; Hypoglycemic Agents; Kidney; Liver; Male; Metformin; Metoprolol; Muscle, Skeletal; Organ Culture Techniques; Random Allocation; Rats; Rats, Wistar | 2016 |
[Effects of metoprolol or/and pravastatin on the pharmacokinetics of metformin in rats].
Topics: Animals; Chromatography, High Pressure Liquid; Drug Interactions; Male; Metformin; Metoprolol; Pravastatin; Rats; Rats, Sprague-Dawley | 2017 |
Oral Manifestations of Commonly Prescribed Drugs.
Topics: Albuterol; Amlodipine; Anticonvulsants; Antihypertensive Agents; Atorvastatin; Bisphosphonate-Associated Osteonecrosis of the Jaw; Bronchodilator Agents; Deprescriptions; Drug Hypersensitivity; Fluorides; Gingival Overgrowth; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperpigmentation; Hypoglycemic Agents; Lisinopril; Losartan; Metformin; Metoprolol; Mouth Diseases; Omeprazole; Oral Hygiene; Proton Pump Inhibitors; Simvastatin; Thyroxine; Toothpastes; Xerostomia | 2020 |
Medicine designed to combat diseases of affluence affects the early development of fish. How do plastic microparticles contribute?
Topics: Animals; Carps; Enalapril; Metformin; Metoprolol; Microplastics; Pharmaceutical Preparations; Plastics; Polystyrenes; Water; Water Pollutants, Chemical; Zebrafish | 2023 |