metformin has been researched along with melatonin in 33 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (9.09) | 29.6817 |
| 2010's | 20 (60.61) | 24.3611 |
| 2020's | 10 (30.30) | 2.80 |
| Authors | Studies |
|---|---|
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Bakir, IH; Hussain, SA; Hussein, KI; Ismail, SH; Kadhim, HM; Khalaf, BH; Sahib, AS | 1 |
| Hussain, SA; Hussein, KI; Ismail, SH; Khadim, HM; Khalaf, BH; Sahib, AS | 1 |
| Kapoor, S | 1 |
| Anikin, IV; Anisimov, VN; Egormin, PA; Karkach, AS; Piskunova, TS; Popovich, IG; Romanyukha, AA; Tyndyk, ML; Yurova, MN; Zabezhinski, MA | 1 |
| Anisimov, VN; Deriabina, ON; Plotnikova, NA | 1 |
| Chesneau, D; Collet, A; Dupont, J; Lomet, D; Malpaux, B; Menassol, JB; Scaramuzzi, RJ; Tautou, C | 1 |
| Anisimov, VN; Demidov, DV; Kharitonova, TV; Man'cheva, TA; Pashkevich, IV; Plotnikova, NA | 1 |
| Lemos, AJ; Luna, RL; Nunes, AK; Peixoto, CA; Rocha, SW; Santos, HM; Silva, AK; Teixeira, AA; Wanderley-Teixeira, V | 1 |
| Akbari, G; Asghari, A; Meghdadi, A; Mortazavi, P | 1 |
| Hoang, J; Matveyenko, AV; Nguyen, A; Rakshit, K; Thomas, AP; Vongbunyong, K | 1 |
| Brown, RE; Buryanek, J; McGuire, MF | 1 |
| Białas, AJ; Górski, P; Makowska, J; Miłkowska-Dymanowska, J; Piotrowski, WJ; Wardzynska, A | 1 |
| Bojkova, B; Demkow, U; Kurhaluk, N; Kyriienko, S; Radkowski, M; Winklewski, PJ; Zaitseva, OV | 1 |
| Anagnostou, E | 1 |
| Jupp, PW | 1 |
| Bojková, B; Kurhaluk, N; Winklewski, PJ | 1 |
| Farquhar, C; Hodgson, R; Jordan, V; Mackenzie-Proctor, R; Showell, MG | 1 |
| Adamkov, M; Bojková, B; Kajo, K; Kubatka, P; Péč, M; Solár, P | 1 |
| Aliasgharzadeh, A; Amini, P; Farhood, B; Motevaseli, E; Musa, AE; Najafi, M; Rezaeyan, A; Shabeeb, D; Tavassoli, A | 1 |
| Amini, P; Cheki, M; Hassanzadeh, G; Musa, AE; Najafi, M; Shabeeb, D | 1 |
| Banaszewska, B; Pawelczyk, L; Spaczynski, R | 1 |
| Ajjan, RA; Al Azdi, Z; Aslam, F; Churchill, R; Mishu, MP; Philip, S; Siddiqi, N; Stubbs, B; Tirbhowan, N; Uphoff, E; Wright, J | 1 |
| Anisimov, VN; Baldueva, IA; Berstein, LM; Latipova, DK; Novik, AV; Protsenko, SA; Semenova, AI; Semiglazova, TY; Tkachenko, EV; Zhuk, IN | 1 |
| Arinno, A; Arunsak, B; Chattipakorn, N; Chattipakorn, SC; Chunchai, T; Kerdphoo, S; Khuanjing, T; Maneechote, C; Ongnok, B; Prathumsap, N; Shinlapawittayatorn, K | 1 |
| Kurhaluk, N; Tkachenko, H | 1 |
| Huang, C; Huo, L; Khan, FA; Pandupuspitasari, NS; Sun, F; Wang, Y; Wu, D; Zhang, K | 1 |
| Chen, J; Dong, K; Fan, R; Ma, D; Peng, X; Shi, X; Xie, L; Xu, W; Yang, Y; Yu, X; Zhang, S | 1 |
| Agarwal, SM; Ahsan, ZA; Cohn, T; Duncan, MJ; Faulkner, GEJ; Hahn, M; Lockwood, JT; Remington, G; Stogios, N; Takeuchi, H; Taylor, VH | 1 |
| Arinno, A; Chattipakorn, N; Chattipakorn, SC; Chunchai, T; Khuanjing, T; Maneechote, C; Ongnok, B; Pantiya, P; Pintana, H; Prathumsap, N | 1 |
| Arinno, A; Arunsak, B; Chattipakorn, N; Chattipakorn, SC; Chunchai, T; Kerdphoo, S; Khuanjing, T; Maneechote, C; Nawara, W; Prathumsap, N; Shinlapawittayatorn, K | 1 |
7 review(s) available for metformin and melatonin
| Article | Year |
|---|---|
Geroprotectors as a therapeutic strategy for COPD - where are we now?
Topics: Aging; Disease Progression; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Melatonin; Metformin; Oxidative Stress; Pulmonary Disease, Chronic Obstructive; Quality of Life; Sirolimus; Testosterone; Vitamin D | 2017 |
Clinical trials in autism spectrum disorder: evidence, challenges and future directions.
Topics: Adrenergic alpha-Agonists; Adrenergic Uptake Inhibitors; Aggression; Antipsychotic Agents; Aripiprazole; Atomoxetine Hydrochloride; Attention Deficit Disorder with Hyperactivity; Autism Spectrum Disorder; Central Nervous System Depressants; Central Nervous System Stimulants; Clinical Trials as Topic; Evidence-Based Medicine; Humans; Hypoglycemic Agents; Irritable Mood; Melatonin; Metformin; Methylphenidate; Obesity; Outcome Assessment, Health Care; Precision Medicine; Risperidone; Sleep; Sleep Wake Disorders | 2018 |
Inositol for subfertile women with polycystic ovary syndrome.
Topics: Abortion, Spontaneous; Administration, Oral; Birth Rate; Clomiphene; Combined Modality Therapy; Female; Fertility Agents, Female; Fertilization in Vitro; Folic Acid; Humans; Hypoglycemic Agents; Infertility, Female; Inositol; Live Birth; Melatonin; Metformin; Ovulation Induction; Polycystic Ovary Syndrome; Pregnancy; Pregnancy, Multiple; Randomized Controlled Trials as Topic; Vitamin B Complex | 2018 |
Current and future aspects of several adjunctive treatment strategies in polycystic ovary syndrome.
Topics: Antioxidants; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemic Agents; Inositol; Melatonin; Metformin; Polycystic Ovary Syndrome; Resveratrol; Vitamin B Complex | 2019 |
Interventions for preventing type 2 diabetes in adults with mental disorders in low- and middle-income countries.
Topics: Adult; Aged; Antidepressive Agents, Tricyclic; Antioxidants; Antipsychotic Agents; Blood Glucose; Body Mass Index; Developing Countries; Diabetes Mellitus, Type 2; Fasting; Female; Humans; Hypoglycemic Agents; Male; Melatonin; Mental Disorders; Metformin; Middle Aged; Patient Dropouts; Placebos; Randomized Controlled Trials as Topic; Schizophrenia; Selective Serotonin Reuptake Inhibitors | 2021 |
Importance of Bmal1 in Alzheimer's disease and associated aging-related diseases: Mechanisms and interventions.
Topics: Adiponectin; Aging; Alzheimer Disease; ARNTL Transcription Factors; Diabetes Mellitus, Type 2; Humans; Melatonin; Metformin | 2022 |
Pharmacological interventions for prevention of weight gain in people with schizophrenia.
Topics: Antipsychotic Agents; Betahistine; Famotidine; Fluoxetine; Humans; Melatonin; Metformin; Nausea; Nizatidine; Ranitidine; Reboxetine; Schizophrenia; Topiramate; Weight Gain | 2022 |
2 trial(s) available for metformin and melatonin
| Article | Year |
|---|---|
Effects of melatonin and zinc on lipid profile and renal function in type 2 diabetic patients poorly controlled with metformin.
Topics: Adult; Albuminuria; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Humans; Hypoglycemic Agents; Kidney; Lipids; Male; Melatonin; Metformin; Middle Aged; Zinc Acetate | 2006 |
Effects of melatonin and zinc on glycemic control in type 2 diabetic patients poorly controlled with metformin.
Topics: Adult; Antioxidants; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Iraq; Male; Melatonin; Metformin; Middle Aged; Zinc Acetate | 2006 |
24 other study(ies) available for metformin and melatonin
| Article | Year |
|---|---|
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Strategies to control antipsychotic-induced weight gain.
Topics: Anti-Obesity Agents; Antipsychotic Agents; Awareness; Body Weight; Bupropion; Clinical Competence; Fructose; Humans; Hypoglycemic Agents; Melatonin; Metformin; Obesity; Topiramate; Treatment Outcome; Weight Gain | 2008 |
Metformin extends life span of HER-2/neu transgenic mice and in combination with melatonin inhibits growth of transplantable tumors in vivo.
Topics: Adenocarcinoma; Age Factors; Animals; Female; Longevity; Male; Mammary Neoplasms, Animal; Melatonin; Metformin; Mice; Mice, Transgenic; Receptor, ErbB-2 | 2010 |
[Melatonin and metformin inhibit skin carcinogenesis induced by benz(a)pyrene in mice].
Topics: Animals; Anticarcinogenic Agents; Antioxidants; Carcinoma, Squamous Cell; Catalase; Central Nervous System Depressants; Hypoglycemic Agents; Male; Malondialdehyde; Melatonin; Metformin; Mice; Mice, Inbred Strains; Pyrenes; Random Allocation; Skin Neoplasms | 2010 |
The effect of an intracerebroventricular injection of metformin or AICAR on the plasma concentrations of melatonin in the ewe: potential involvement of AMPK?
Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Brain; Circadian Rhythm; Female; Infusions, Intraventricular; Melatonin; Metformin; Ribonucleotides; Sheep | 2011 |
Melatonin and metformin inhibit skin carcinogenesis and lipid peroxidation induced by benz(a)pyrene in female mice.
Topics: Animals; Antioxidants; Benzo(a)pyrene; Cell Transformation, Neoplastic; Female; Lipid Peroxidation; Malondialdehyde; Melatonin; Metformin; Mice; Reactive Oxygen Species; Skin; Skin Neoplasms | 2011 |
Effect of the combination of metformin hydrochloride and melatonin on oxidative stress before and during pregnancy, and biochemical and histopathological analysis of the livers of rats after treatment for polycystic ovary syndrome.
Topics: Animals; Antioxidants; Drug Therapy, Combination; Female; Liver; Melatonin; Metformin; Oxidative Stress; Polycystic Ovary Syndrome; Pregnancy; Rats; Rats, Wistar; Treatment Outcome | 2014 |
Effects of melatonin and metformin co-administration on testicular ischemia/reperfusion injury in rats.
Topics: Animals; Antioxidants; Drug Therapy, Combination; Male; Melatonin; Metformin; Random Allocation; Rats; Rats, Wistar; Reperfusion Injury; Testis | 2016 |
Administration of Melatonin and Metformin Prevents Deleterious Effects of Circadian Disruption and Obesity in Male Rats.
Topics: Adiposity; Animals; Central Nervous System Depressants; Circadian Rhythm; Glucose Intolerance; Hypoglycemic Agents; Insulin Resistance; Male; Melatonin; Metformin; Obesity; Rats | 2016 |
Metformin and Melatonin in Adrenocortical Carcinoma: Morphoproteomics and Biomedical Analytics Provide Proof of Concept in a Case Study.
Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Adult; Antioxidants; Biomarkers, Tumor; Drug Therapy, Combination; Female; Humans; Hypoglycemic Agents; Immunohistochemistry; Melatonin; Metformin; Prognosis; Proteomics; Signal Transduction | 2017 |
Melatonin and Metformin Diminish Oxidative Stress in Heart Tissue in a Rat Model of High Fat Diet and Mammary Carcinogenesis.
Topics: Animals; Antioxidants; Catalase; Diet, High-Fat; Female; Glutathione Peroxidase; Heart; Lipid Peroxidation; Mammary Neoplasms, Experimental; Melatonin; Metformin; Myocardium; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances | 2018 |
A complex systems approach to cancer prevention.
Topics: beta-Glucans; Decision Support Techniques; Diet; Drug Synergism; Energy Metabolism; Exercise; Glucose; Homeostasis; Humans; Inflammation; Melatonin; Meta-Analysis as Topic; Metformin; Models, Biological; Neoplasms; Stress, Physiological; Systems Theory; Vitamins | 2018 |
Liver antioxidant and aerobic status improves after metformin and melatonin administration in a rat model of high-fat diet and mammary carcinogenesis.
Topics: Aerobiosis; Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Carcinogenesis; Diet, High-Fat; Female; L-Lactate Dehydrogenase; Lipid Peroxidation; Liver; Male; Mammary Neoplasms, Animal; Melatonin; Metformin; Oxidation-Reduction; Rats, Sprague-Dawley; Succinate Dehydrogenase; Triglycerides | 2018 |
Metformin and melatonin improve histopathological outcome of NMU-induced mammary tumors in rats.
Topics: Animals; Cell Proliferation; Diet, High-Fat; Female; Mammary Neoplasms, Experimental; Melatonin; Metformin; Methylnitrosourea; Rats; Rats, Sprague-Dawley | 2019 |
Mitigation of Radiation-Induced Lung Pneumonitis and Fibrosis Using Metformin and Melatonin: A Histopathological Study.
Topics: Animals; Antioxidants; Disease Models, Animal; Melatonin; Metformin; Mice; Protective Agents; Radiation Exposure; Radiation Pneumonitis | 2019 |
Protection from Radiation-induced Damage in Rat's Ileum and Colon by Combined Regimens of Melatonin and Metformin: A Histopathological Study.
Topics: Animals; Colon; Drug Therapy, Combination; Enteritis; Humans; Ileum; Male; Melatonin; Metformin; Models, Animal; Radiation Injuries; Radiation-Protective Agents; Rats; Rats, Wistar; Whole-Body Irradiation | 2020 |
Melatonin and Metformin Failed to Modify the Effect of Dacarbazine in Melanoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Dacarbazine; Humans; Melanoma; Melatonin; Metformin; Quality of Life | 2021 |
Cardioprotective effects of melatonin and metformin against doxorubicin-induced cardiotoxicity in rats are through preserving mitochondrial function and dynamics.
Topics: Animals; Antibiotics, Antineoplastic; Cardiotonic Agents; Cardiotoxicity; Cell Line; Dose-Response Relationship, Drug; Doxorubicin; Male; Melatonin; Metformin; Mitochondria; Mitochondrial Dynamics; Myocytes, Cardiac; Rats; Rats, Wistar | 2021 |
Effects of melatonin and metformin in preventing lysosome-induced autophagy and oxidative stress in rat models of carcinogenesis and the impact of high-fat diet.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Autophagy; Carcinogenesis; Diet, High-Fat; Female; Humans; Lysosomes; Mammary Neoplasms, Experimental; Melatonin; Metformin; Oxidative Stress; Rats; Rats, Sprague-Dawley | 2022 |
Perfluorooctanoic acid alters the developmental trajectory of female germ cells and embryos in rodents and its potential mechanism.
Topics: Animals; Caprylates; Female; Fetal Growth Retardation; Fluorocarbons; Germ Cells; Humans; Melatonin; Metformin; Rodentia; Serine | 2022 |
Melatonin and metformin counteract cognitive dysfunction equally in male rats with doxorubicin-induced chemobrain.
Topics: Animals; Chemotherapy-Related Cognitive Impairment; Cognitive Dysfunction; Doxorubicin; Encephalitis; Male; Melatonin; Metformin; Oxidative Stress; Rats; Rats, Wistar | 2023 |
Melatonin and metformin ameliorated trastuzumab-induced cardiotoxicity through the modulation of mitochondrial function and dynamics without reducing its anticancer efficacy.
Topics: Animals; Cardiotoxicity; Inflammation; Male; Melatonin; Metformin; Mitochondria; Rats; Rats, Wistar; Saline Solution; Trastuzumab; Ventricular Dysfunction, Left | 2023 |