metformin and mefloquine

metformin has been researched along with mefloquine in 5 studies

Research

Studies (5)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	5 (100.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Aldape, KD; Alfred Yung, WK; Conrad, CA; de Groot, JF; Gilbert, MR; Groves, MD; Hess, KR; Loghin, ME; Mammoser, AG; Maraka, S; Melguizo-Gavilanes, I; O'Brien, BJ; Penas-Prado, M; Puduvalli, VK; Sulman, EP; Tremont-Lukats, IW	1
Nevin, RL	1
Groves, MD; Maraka, S; Penas-Prado, M	1
Bhatia, SN; Grilo Ruivo, MT; Lemos Rocha, LF; Mancio-Silva, L; Marques, S; Mota, MM; Vera, IM	1

Reviews

1 review(s) available for metformin and mefloquine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Trials

1 trial(s) available for metformin and mefloquine

Article	Year
Phase 1 lead-in to a phase 2 factorial study of temozolomide plus memantine, mefloquine, and metformin as postradiation adjuvant therapy for newly diagnosed glioblastoma. Cancer, 2019, 02-01, Volume: 125, Issue:3 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemotherapy, Adjuvant; Clinical Trials, Phase II as Topic; Female; Glioblastoma; Humans; Male; Maximum Tolerated Dose; Mefloquine; Memantine; Metformin; Middle Aged; Progression-Free Survival; Radiotherapy, Adjuvant; Research Design; Temozolomide; Treatment Outcome; Young Adult	2019

Article

Year

Phase 1 lead-in to a phase 2 factorial study of temozolomide plus memantine, mefloquine, and metformin as postradiation adjuvant therapy for newly diagnosed glioblastoma.

Cancer, 2019, 02-01, Volume: 125, Issue:3

Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemotherapy, Adjuvant; Clinical Trials, Phase II as Topic; Female; Glioblastoma; Humans; Male; Maximum Tolerated Dose; Mefloquine; Memantine; Metformin; Middle Aged; Progression-Free Survival; Radiotherapy, Adjuvant; Research Design; Temozolomide; Treatment Outcome; Young Adult

2019

Other Studies

3 other study(ies) available for metformin and mefloquine

Article	Year
Unexpectedly low rates of neuropsychiatric adverse effects associated with mefloquine repurposed for the treatment of glioblastoma. Cancer, 2019, 04-15, Volume: 125, Issue:8 Topics: Glioblastoma; Humans; Mefloquine; Memantine; Metformin; Temozolomide	2019
Reply to Unexpectedly low rates of neuropsychiatric adverse effects associated with mefloquine repurposed for the treatment of glioblastoma. Cancer, 2019, 04-15, Volume: 125, Issue:8 Topics: Glioblastoma; Humans; Mefloquine; Memantine; Metformin; Temozolomide	2019
Targeting liver stage malaria with metformin. JCI insight, 2019, 12-19, Volume: 4, Issue:24 Topics: Animals; Antimalarials; Cells, Cultured; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Repositioning; Drug Therapy, Combination; Hepatocytes; Humans; Inhibitory Concentration 50; Liver; Malaria; Male; Mefloquine; Metformin; Mice; Parasite Load; Parasitic Sensitivity Tests; Plasmodium berghei; Plasmodium falciparum; Primaquine; Primary Cell Culture	2019