metformin and losartan

metformin has been researched along with losartan in 28 studies

Research

Studies (28)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	3 (10.71)	29.6817
2010's	20 (71.43)	24.3611
2020's	5 (17.86)	2.80

Authors

Authors	Studies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Lombardo, F; Obach, RS; Waters, NJ	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Giacomini, KM; Huang, Y; Khuri, N; Kido, Y; Kosaka, A; Morrissey, KM; Sali, A; Wittwer, MB; Zhang, X; Zur, AA	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Bundrick, JB; Litin, SC	1
Balink, H; de Graaf, W; Grond, J; Hemmelder, MH	1
Harrison, SA; Jones, FJ; Shaw, JC; Torres, DM; Ward, JA; Williams, CD	1
Pirola, CJ; Sookoian, S	1
Clouatre, DL; Preuss, HG; Rao, SN	1
Chalasani, N; Corey, KE	1
Araki, H; Araki, S; Chin-Kanasaki, M; Deji, N; Haneda, M; Isshiki, K; Kashiwagi, A; Koya, D; Kume, S; Maegawa, H; Nishiyama, A; Tanaka, Y; Uzu, T	1
Arafat, T; Idkaidek, N	1
Barreto-Torres, G; Hernández, JS; Javadov, S; Khuchua, Z; Kuznetsov, AV	1
Böhmer, FD; Kirches, E; Mawrin, C; Pachow, D; Petermann, A; Wallesch, M; Wilisch-Neumann, A	1
Ahn, HY; Ha, TS; Park, HY; Seong, SB	1
Jang, HB; Jeon, JY; Kim, MG; Kim, SY; Lim, CH; Moon, SJ	1
Ahmed, M; Ali, M; Ayatollahi, SA; Esfahanizadeh, M; Haider, SM; Hasan, A; Khan, KM; Kobarfard, F	1
Glick, A; Johnson, C; Sista, V	1
Aung, TKK; Chua, MWJ; Chuah, TY	1
da Silva, SVS; de Carvalho, WC; de Freitas Santos Júnior, A; de Jesus, ACL; de Sousa, TL; Dos Santos, LC; Korn, MDGA; Santos, DCMB; Souza, LA	1
Ahante, E; Anachuna, KK; Asiwe, JN; Ben-Azu, B; Edje, KE; Eduviere, AT; Moke, EG; Oghoghovwe, IJ; Omogbai, EKI; Omogbiya, AI; Osagie-Eweka, SDE; Uchendu, AP; Umukoro, EK	1
Tchernev, G	1

Reviews

1 review(s) available for metformin and losartan

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Trials

2 trial(s) available for metformin and losartan

Article	Year
Rosiglitazone versus rosiglitazone and metformin versus rosiglitazone and losartan in the treatment of nonalcoholic steatohepatitis in humans: a 12-month randomized, prospective, open- label trial. Hepatology (Baltimore, Md.), 2011, Volume: 54, Issue:5 Topics: Adolescent; Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Biopsy; Drug Therapy, Combination; Fatty Liver; Female; Humans; Hypoglycemic Agents; Liver; Losartan; Male; Metformin; Middle Aged; Non-alcoholic Fatty Liver Disease; Prospective Studies; Rosiglitazone; Thiazolidinediones; Treatment Outcome; Young Adult	2011
Phase 1 and Pharmacokinetic Drug-Drug Interaction Study of Metformin, Losartan, and Linagliptin Coadministered With DW1029M in Healthy Volunteers. Clinical pharmacology in drug development, 2017, Volume: 6, Issue:4 Topics: Adult; Area Under Curve; Cross-Over Studies; Drug Administration Schedule; Drug Interactions; Healthy Volunteers; Humans; Linagliptin; Losartan; Male; Metformin; Middle Aged; Morus; Plant Extracts; Pueraria; Young Adult	2017

Article

Year

Rosiglitazone versus rosiglitazone and metformin versus rosiglitazone and losartan in the treatment of nonalcoholic steatohepatitis in humans: a 12-month randomized, prospective, open- label trial.

Hepatology (Baltimore, Md.), 2011, Volume: 54, Issue:5

Topics: Adolescent; Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Biopsy; Drug Therapy, Combination; Fatty Liver; Female; Humans; Hypoglycemic Agents; Liver; Losartan; Male; Metformin; Middle Aged; Non-alcoholic Fatty Liver Disease; Prospective Studies; Rosiglitazone; Thiazolidinediones; Treatment Outcome; Young Adult

2011

Phase 1 and Pharmacokinetic Drug-Drug Interaction Study of Metformin, Losartan, and Linagliptin Coadministered With DW1029M in Healthy Volunteers.

Clinical pharmacology in drug development, 2017, Volume: 6, Issue:4

Topics: Adult; Area Under Curve; Cross-Over Studies; Drug Administration Schedule; Drug Interactions; Healthy Volunteers; Humans; Linagliptin; Losartan; Male; Metformin; Middle Aged; Morus; Plant Extracts; Pueraria; Young Adult

2017

Other Studies

25 other study(ies) available for metformin and losartan

Article	Year
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
Discovery of potent, selective multidrug and toxin extrusion transporter 1 (MATE1, SLC47A1) inhibitors through prescription drug profiling and computational modeling. Journal of medicinal chemistry, 2013, Feb-14, Volume: 56, Issue:3 Topics: Computer Simulation; Fluorescent Dyes; Organic Cation Transport Proteins; Prescription Drugs	2013
Clinical pearls in general internal medicine. Mayo Clinic proceedings, 2011, Volume: 86, Issue:1 Topics: Abdominal Pain; Adrenergic alpha-1 Receptor Antagonists; Adult; Aged; Androgen Antagonists; Anti-Infective Agents, Urinary; Antihypertensive Agents; Calcium Channel Blockers; Creatinine; Diagnosis, Differential; Female; Fenofibrate; Gout; Humans; Hypoglycemic Agents; Hypolipidemic Agents; Internal Medicine; Losartan; Male; Metformin; Nifedipine; Potassium; Sulfonamides; Tamsulosin; Trimethoprim; Ureteral Calculi; Vitamin B 12 Deficiency	2011
Scintigraphic diagnosis of Erdheim-Chester disease. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Jun-01, Volume: 29, Issue:16 Topics: Aged; Amlodipine; Antihypertensive Agents; Diabetes Mellitus, Type 2; Drug Combinations; Erdheim-Chester Disease; Gated Blood-Pool Imaging; Humans; Hydrochlorothiazide; Hypoglycemic Agents; Hypolipidemic Agents; Imidazoles; Knee Joint; Losartan; Male; Metformin; Positron-Emission Tomography; Prostatic Neoplasms; Simvastatin	2011
Targeting the renin-angiotensin system: potential beneficial effects of the angiotensin II receptor blockers in patients with nonalcoholic steatohepatitis. Hepatology (Baltimore, Md.), 2011, Volume: 54, Issue:6 Topics: Fatty Liver; Female; Humans; Losartan; Male; Metformin; Thiazolidinediones	2011
Bitter melon extracts in diabetic and normal rats favorably influence blood glucose and blood pressure regulation. Journal of medicinal food, 2011, Volume: 14, Issue:12 Topics: Animals; Blood Glucose; Blood Pressure; Cucurbitaceae; Diabetes Mellitus, Experimental; Fruit; Glucose Tolerance Test; Hypoglycemic Agents; Losartan; Male; Metformin; NG-Nitroarginine Methyl Ester; Nitric Oxide; Plant Extracts; Rats; Rats, Sprague-Dawley; Rats, Wistar; Renin-Angiotensin System	2011
Should combination therapy be the paradigm for future nonalcoholic steatohepatitis clinical trials? Hepatology (Baltimore, Md.), 2011, Volume: 54, Issue:5 Topics: Fatty Liver; Female; Humans; Losartan; Male; Metformin; Non-alcoholic Fatty Liver Disease; Rosiglitazone; Thiazolidinediones	2011
Role of angiotensin II-mediated AMPK inactivation on obesity-related salt-sensitive hypertension. Biochemical and biophysical research communications, 2012, Feb-17, Volume: 418, Issue:3 Topics: AMP-Activated Protein Kinases; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Diet, High-Fat; Disease Models, Animal; Hypertension; Kidney; Losartan; Metabolic Syndrome; Metformin; Mice; Mice, Inbred C57BL; Obesity; Phosphorylation; Sodium; Sodium, Dietary	2012
Saliva versus plasma pharmacokinetics: theory and application of a salivary excretion classification system. Molecular pharmaceutics, 2012, Aug-06, Volume: 9, Issue:8 Topics: Acetates; Anthraquinones; Azithromycin; Benzhydryl Compounds; Cinacalcet; Cloxacillin; Cresols; Cyclopropanes; Female; Fluorobenzenes; Humans; Hydrochlorothiazide; Losartan; Male; Metformin; Naphthalenes; Phenylpropanolamine; Piroxicam; Pyrazines; Pyrimidines; Quinolines; Rosuvastatin Calcium; Saliva; Sitagliptin Phosphate; Sulfides; Sulfonamides; Tamsulosin; Tolterodine Tartrate; Triazoles	2012
Crosstalk between AMPK activation and angiotensin II-induced hypertrophy in cardiomyocytes: the role of mitochondria. Journal of cellular and molecular medicine, 2014, Volume: 18, Issue:4 Topics: AMP-Activated Protein Kinases; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Cardiomegaly; Gene Expression Regulation; Losartan; Metformin; Mitochondria; Myocytes, Cardiac; Nitric Oxide Synthase Type III; Rats; Receptor, Angiotensin, Type 1; Signal Transduction; Sirtuin 1; Tumor Suppressor Protein p53	2014
Re-evaluation of cytostatic therapies for meningiomas in vitro. Journal of cancer research and clinical oncology, 2014, Volume: 140, Issue:8 Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Dacarbazine; DNA Methylation; DNA Modification Methylases; DNA Repair Enzymes; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Erlotinib Hydrochloride; Humans; Hydroxyurea; Losartan; Meningeal Neoplasms; Meningioma; Metformin; Mifepristone; Neurofibromin 2; Promoter Regions, Genetic; Quinazolines; Radiation Tolerance; Tamoxifen; Temozolomide; Tumor Suppressor Proteins; Verapamil	2014
Angiotensin II Modulates p130Cas of Podocytes by the Suppression of AMP-Activated Protein Kinase. Journal of Korean medical science, 2016, Volume: 31, Issue:4 Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blotting, Western; Cell Line; Cell Nucleus; Crk-Associated Substrate Protein; Cytoplasm; Focal Adhesion Kinase 1; Losartan; Metformin; Mice; Microscopy, Confocal; Podocytes; Protein Kinase Inhibitors; Ribonucleotides; Signal Transduction	2016
Short Communication - Synthesis of drug metal complexes and their influence on human platelet aggregation. Pakistan journal of pharmaceutical sciences, 2018, Volume: 31, Issue:2 Topics: Coordination Complexes; Drug Evaluation, Preclinical; Fluconazole; Humans; Isoniazid; Losartan; Metformin; Platelet Aggregation; Platelet Aggregation Inhibitors; Pyrazinamide	2018
Oral Manifestations of Commonly Prescribed Drugs. American family physician, 2020, 11-15, Volume: 102, Issue:10 Topics: Albuterol; Amlodipine; Anticonvulsants; Antihypertensive Agents; Atorvastatin; Bisphosphonate-Associated Osteonecrosis of the Jaw; Bronchodilator Agents; Deprescriptions; Drug Hypersensitivity; Fluorides; Gingival Overgrowth; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperpigmentation; Hypoglycemic Agents; Lisinopril; Losartan; Metformin; Metoprolol; Mouth Diseases; Omeprazole; Oral Hygiene; Proton Pump Inhibitors; Simvastatin; Thyroxine; Toothpastes; Xerostomia	2020
More Than Meets the Eye: A Patient with Hand Swelling and Newly Diagnosed Diabetes Mellitus. The American journal of medicine, 2021, Volume: 134, Issue:11 Topics: Aged; Amlodipine; Anemia; Antihypertensive Agents; Blood Sedimentation; C-Reactive Protein; Diabetes Mellitus, Type 2; Edema; Glucocorticoids; Hand; Humans; Hypertension; Hypoglycemic Agents; Losartan; Male; Metformin; Prednisolone; Rotator Cuff Injuries; Syndrome; Synovitis	2021
Effect of losartan potassium, metformin hydrochloride, and simvastatin on in vitro bioaccessibility of Cu, Fe, Mn, and Zn in oat flour from Brazil. Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS), 2022, Volume: 73 Topics: Avena; Brazil; Flour; Humans; Losartan; Metformin; Micronutrients; Simvastatin; Zinc	2022
Co-administration of metformin and/or glibenclamide with losartan reverse N Microvascular research, 2023, Volume: 147 Topics: Animals; Antihypertensive Agents; Blood Pressure; Diabetes Mellitus, Experimental; Esters; Glyburide; Hypertension; Hypoglycemic Agents; Losartan; Metformin; NG-Nitroarginine Methyl Ester; Rats; Streptozocin; Water	2023
NITROSOGENESIS OF SKIN CANCER: THE NITROSAMINE CONTAMINATION IN THE CALCIUM CHANNEL BLOCKERS (AMLODIPINE), BETA BLOCKERS (BISOPROLOL), SARTANS (VALSARTAN/LOSARTAN), ACE INHIBITORS (PERINDOPRIL/ENALAPRIL), TRICYCLIC ANTIDEPRESSANTS (MELITRACEN), SSRIS (PAR Georgian medical news, 2023, Issue:339 Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antidepressive Agents, Tricyclic; Bisoprolol; Calcium Channel Blockers; Enalapril; Humans; Incidence; Losartan; Metformin; Paroxetine; Perindopril; Selective Serotonin Reuptake Inhibitors; Serotonin and Noradrenaline Reuptake Inhibitors; Skin Neoplasms; Valsartan; Venlafaxine Hydrochloride	2023