metformin and leuprolide

metformin has been researched along with leuprolide in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's2 (40.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Jakubowicz, DJ; Nestler, JE1
Chang, RJ; de Ziegler, D; Meldrum, DR; Pellicer, A; Schoolcraft, WB; Scott, RT1
Basu, A; Cappola, AR; Fuller, C; Iqbal, N; Kaul, S; Patel, SM; Ratcliffe, SJ; Reilly, MP; Rickels, MR; Scattergood, T1
Crisosto, N; Echiburú, B; Ladrón de Guevara, A; Maliqueo, M; Pérez, V; Preisler, J; Sánchez, F; Sir-Petermann, T1

Trials

2 trial(s) available for metformin and leuprolide

ArticleYear
Decreases in ovarian cytochrome P450c17 alpha activity and serum free testosterone after reduction of insulin secretion in polycystic ovary syndrome.
    The New England journal of medicine, 1996, Aug-29, Volume: 335, Issue:9

    Topics: 17-alpha-Hydroxyprogesterone; Adolescent; Adult; Blood Glucose; Female; Humans; Hydroxyprogesterones; Hyperandrogenism; Hypoglycemic Agents; Insulin; Leuprolide; Luteinizing Hormone; Metformin; Obesity; Polycystic Ovary Syndrome; Steroid 17-alpha-Hydroxylase; Testosterone

1996
Effects of metformin and leuprolide acetate on insulin resistance and testosterone levels in nondiabetic postmenopausal women: a randomized, placebo-controlled trial.
    Fertility and sterility, 2010, Volume: 94, Issue:6

    Topics: Aged; Double-Blind Method; Female; Fertility Agents, Female; Follicle Stimulating Hormone; Humans; Hypoglycemic Agents; Insulin Resistance; Leuprolide; Longitudinal Studies; Luteinizing Hormone; Metformin; Middle Aged; Placebos; Postmenopause; Testosterone

2010

Other Studies

3 other study(ies) available for metformin and leuprolide

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Adjuncts for ovarian stimulation: when do we adopt "orphan indications" for approved drugs?
    Fertility and sterility, 2009, Volume: 92, Issue:1

    Topics: Androgens; Aspirin; Contraceptives, Oral; Dopamine Agonists; Estrogens; Female; Fertilization in Vitro; Human Growth Hormone; Humans; Leuprolide; Metformin; Orphan Drug Production; Ovulation Induction; Polycystic Ovary Syndrome

2009
Improvement of hyperandrogenism and hyperinsulinemia during pregnancy in women with polycystic ovary syndrome: possible effect in the ovarian follicular mass of their daughters.
    Fertility and sterility, 2012, Volume: 97, Issue:1

    Topics: Adult; Anti-Mullerian Hormone; Birth Weight; Diabetes, Gestational; Female; Fertility Agents, Female; Humans; Hyperandrogenism; Hyperinsulinism; Hypoglycemic Agents; Infant, Low Birth Weight; Infant, Newborn; Insulin; Leuprolide; Metformin; Ovarian Follicle; Polycystic Ovary Syndrome; Pregnancy; Prenatal Exposure Delayed Effects; Testosterone; Young Adult

2012