metformin has been researched along with leptin in 136 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (2.94) | 18.2507 |
| 2000's | 49 (36.03) | 29.6817 |
| 2010's | 56 (41.18) | 24.3611 |
| 2020's | 27 (19.85) | 2.80 |
| Authors | Studies |
|---|---|
| Bloomgarden, ZT | 2 |
| Boss, O; Huupponen, R; Koulu, M; Rouru, J; Savontaus, E | 1 |
| Koivunen, RM; Martikainen, HK; Morin-Papunen, LC; Ruokonen, A; Tomás, C | 1 |
| Collier, G; Zimmet, P | 1 |
| Biscotti, D; Cognigni, GE; Colitta, D; Filicori, M; Fiorini, S; Gagliardi, L; Gambineri, A; Morselli-Labate, AM; Pasquali, R; Vicennati, V | 1 |
| Ling Fu, C; McCormick, KL; Mick, GJ; Wang, X | 1 |
| Evans, JL; Gregoire, F; Havel, PJ; Mueller, WM; Stanhope, KL | 1 |
| Bardini, G; Ciani, S; Cremasco, F; Mannucci, E; Mencucci, A; Messeri, G; Ognibene, A; Pierazzuoli, E; Rotella, CM | 1 |
| Kinalska, I; Kinalski, M; Kowalska, I; Straczkowski, M; Wolczyski, S | 1 |
| Bursey, D; Freemark, M | 1 |
| Chang, CT; Chen, CC; Chen, RH; Sheen, LY; Shih, HC; Wang, HJ; Wang, TY | 1 |
| Fontaine, RN; Glueck, CJ; Illig, E; Lang, JE; McCullough, P; Sieve-Smith, L; Streicher, P; Subbiah, MT; Tracy, TM; Wang, P; Weber, K | 1 |
| Yanovski, JA | 1 |
| Tan, BK; Zhang, XF | 1 |
| Bingol, N; Oktenli, C; Ozata, M; Ozdemir, IC | 1 |
| Alemzadeh, R; D'Angelo, L; Holshouser, S; Kay, JP; Langley, G; Smith, P | 1 |
| Born, J; Fehm, HL; Fruehwald-Schultes, B; Kern, W; Oltmanns, KM; Peters, A; Sopke, S; Toschek, B | 1 |
| Oehninger, S; Stadtmauer, LA; Wong, BC | 1 |
| Born, J; Fehm, HL; Kern, W; Oltmanns, KM; Peters, A; Schultes, B | 1 |
| Bar, RS; Bayless, ML; Haynes, WG; Larson, LF; Sinkey, C; Sivitz, WI; Wayson, SM | 1 |
| Kadayifçi, A | 1 |
| Chi, HH; Lin, JJ; Lin, WQ; Ye, BL; Zhao, JZ | 1 |
| Cross, SE; da Silva Xavier, G; Korbutt, GS; Leclerc, I; Rajotte, RV; Rowe, RL; Rutter, GA; Smith, R; Woltersdorf, WW | 1 |
| Alvarez Fidalgo, P; Codoceo, R; Díez, JJ; Iglesias, P | 1 |
| Iguchi, A; Komori, T; Miura, H; Miyazaki, S; Nakamura, J; Yoshida, F | 1 |
| Zhang, YW | 1 |
| Fasshauer, M; Klein, HH; Klein, J; Kraus, D; Meier, B; Ott, V; Perwitz, N; Westphal, S | 1 |
| Bar, RS; Goldner, WS; Haynes, WG; Putz, DM; Sivitz, WI | 1 |
| Corapçioğlu, D; Emral, R; Kamel, N; Köseoğlulari, O; Tonyukuk, V; Uysal, AR | 1 |
| Li, L; Mamputu, JC; Renier, G; Wiernsperger, N | 1 |
| Elbein, SC; Kern, PA; Miles, LM; Rasouli, N; Yao-Borengasser, A | 1 |
| Choi, KH; Huh, JY; Kim, JY; Kim, YW; Moon, KH; Park, SY; Park, YH; Won, KC | 1 |
| Boscaro, M; Grossman, AB; Kola, B; Korbonits, M; Rutter, GA | 1 |
| Fitzgerald, BP; Kennedy, EL; Murphy, BA; Reedy, SE; Sessions, DR; Vick, MM | 1 |
| Bulcão, C; Ferreira, SR; Giuffrida, FM; Ribeiro-Filho, FF | 1 |
| Baptista, T; Beaulieu, S; Contreras, Q; de Mendoza, S; Galeazzi, T; Lacruz, A; Rangel, N; Sandia, I; Vargas, D | 1 |
| Baptista, T; Beaulieu, S; Carrizo, E; Connell, L; Dávila, A; de Baptista, EA; El Fakih, Y; Fernández, V; Galeazzi, T; Gutiérrez, MA; Rangel, N; Serrano, A; Servigna, M; Uzcátegui, E; Uzcátegui, M | 1 |
| Campagna, G; Cento, R; Guido, M; Lanzone, A; Proto, C; Romualdi, D; Selvaggi, L | 1 |
| Fujita, T; Hayakawa, N; Horikawa, Y; Imamura, S; Inagaki, K; Itoh, M; Kakizawa, H; Oda, N; Suzuki, A; Takeda, J; Uchida, Y | 1 |
| Al-Zaman, Y; Aylwin, S | 1 |
| Campagna, G; De Marinis, L; Guido, M; Lanzone, A; Proto, C; Romualdi, D | 1 |
| Ciccarelli, L; Cicero, AF; D'Angelo, A; Derosa, G; Ferrari, I; Fogari, E; Gravina, A; Maffioli, P; Piccinni, MN; Ragonesi, PD; Salvadeo, SA | 1 |
| Aronne, LJ; Neff, LM | 1 |
| Ishida, K; Kamata, K; Kobayashi, T; Matsumoto, T; Noguchi, E; Yamada, N | 1 |
| Gedik, O; Nar, A | 1 |
| Alvarez-Blasco, F; Escobar-Morreale, HF; Luque-Ramírez, M | 1 |
| Balabolkin, MI; Klebanova, EM; Kreminskaia, VM; Kuzin, AG; Mamaeva, GG; Tel'nova, ME | 1 |
| Chevalier, S; Gougeon, R; Lamarche, M; Morais, JA; Mourad, C | 1 |
| Baptista, T; Carrizo, E; Connell, L; de Baptista, EA; Fernández, I; Fernández, V; Mogollón, J; Prieto, D; Sandia, I; Valbuena, D | 1 |
| Hsu, A; Huang, D; Tan, BK; Waisundara, VY | 1 |
| de Zegher, F; Diaz, M; Ibáñez, L; Lopez-Bermejo, A; Marcos, MV | 1 |
| Hutchison, SK; Meyer, C; Moran, LJ; Teede, HJ; Zoungas, S | 1 |
| Akbas, H; Coban, E; Eray, E; Ozdem, S; Sari, R | 1 |
| Brodowska, A; Marciniak, A; Nawrocka-Rutkowska, J; Sienkiewicz, R; Starczewski, A; Szydłowska, I | 1 |
| Aslanidis, C; Bauer, S; Buechler, C; Farkas, S; Neumeier, M; Schäffler, A; Scherer, MN; Schnitzbauer, A; Schölmerich, J; Wanninger, J; Weigert, J | 1 |
| Kang, B; Li, G; Wang, Y; Yan, L; Yin, Z | 1 |
| Asano, T; Farese, RV; Kahn, CR; Kondo, T; Liu, P; Sajan, MP; Smyth, G; Sopasakis, VR; Suzuki, R; Tran, TT; Winnay, J; Zhao, JJ | 1 |
| Aubert, G; Mansuy, V; Pellerin, L; Pralong, FP; Voirol, MJ | 1 |
| Hirasawa, Y; Ito, M; Kyuki, K; Matsui, Y; Sugiura, T; Toyoshi, T | 1 |
| Baptista, T; Carrizo, E; Connell, L; de Baptista, EA; Fernández, E; Fernández, I; Fernández, V; Mogollón, J; Prieto, D; Sandia, I; Valbuena, D | 1 |
| Jang, EH; Kang, JH; Kim, HK; Park, CS | 1 |
| Haapasalo, A; Hiltunen, M; Kaarniranta, K; Salminen, A; Soininen, H | 1 |
| Asgarani, F; Esteghamati, A; Khalilzadeh, O; Mokhtari, A; Morteza, A; Nakhjavani, M; Rahbari, G | 1 |
| Baptista, T; Carrizo, E; Connell, L; Fernández, E | 1 |
| Aguilar-Salinas, CA; Cruz, M; Gómez-Díaz, RA; Mondragón-González, R; Ortiz-Navarrete, FV; Pool, EC; Solórzano-Santos, F; Talavera, JO; Valladares-Salgado, A; Wacher, NH | 1 |
| Deng, J; Li, J; Sheng, W; Zuo, Z | 1 |
| Chacón, MR; de Zegher, F; Díaz, M; Ibáñez, L; López-Bermejo, A; Maymó-Masip, E; Salvador, C; Vendrell, J | 1 |
| Balfour, DJ; McNeilly, AD; Stewart, CA; Sutherland, C; Williamson, R | 1 |
| Barnea, M; Chapnik, N; Froy, O; Gutman, R; Haviv, L; Madar, Z | 1 |
| Arce-Esquivel, AA; Bayless, DS; Booth, FW; Jenkins, NT; Laughlin, MH; Leidy, HJ; Martin, JS; Padilla, J; Rector, RS | 1 |
| Barrett, HL; Callaway, LK; Coat, S; De Blasio, MJ; Dekker Nitert, M; Gatford, KL; Hague, WM; Houda, CM; McIntyre, HD; Owens, JA; Rowan, JA | 1 |
| Esteghamati, A; Kebriaee-Zadeh, A; Nakhjavani, M; Rashidi, A; Taslimi, S; Tavakkoli, HM | 1 |
| Esteghamati, A; Ghavami, M; Nakhjavani, M; Noshad, S; Rabizadeh, S; Zandieh, A | 1 |
| Andreasson, AN; Carlsson, AC; Wändell, PE | 1 |
| Cakiroglu, Y; Isgoren, S; Vural, B | 1 |
| Grasso, P; Leinung, MC; Novakovic, ZM | 1 |
| Asgarani, F; Esteghamati, A; Ghaneei, A; Mirmiranpour, H; Morteza, A; Nakhjavani, M | 1 |
| Gill, N; Mantzoros, CS; Paruthi, J | 1 |
| Garg, SK; Michels, AW; Shah, VN | 1 |
| Angel, JM; Beltran, L; Blando, J; Checkley, LA; Cho, J; DiGiovanni, J; Hursting, SD; Rho, O | 1 |
| Ahmad, A; Cremers, S; Crew, KD; Feldman, SM; Hershman, DL; Hibshoosh, H; Kalinsky, K; Maurer, M; Refice, S; Taback, B; Wang, A; Xiao, T | 1 |
| Araújo-Vilar, D; Guillín-Amarelle, C; Sánchez-Iglesias, S | 1 |
| Kashyap, SR; Malin, SK | 1 |
| Anifandis, G; Dafopoulos, K; Messini, CI; Messinis, IE | 1 |
| Almonte, V; Bravo, M; Brima, W; Eden, DJ; Kurland, I; Mehdi, SF; Nagajyothi, F; Pessin, JE; Roth, J; Stein, J; Tanowitz, HB; Weiss, LM; Wiese, MM; Zhao, D; Zima, T | 1 |
| Cheng, X; Guo, J; Xie, J | 1 |
| Bernstein, V; Chalchal, HI; Chen, BE; Gelmon, KA; Goodwin, PJ; Hershman, DL; Hobday, TJ; Lemieux, J; Ligibel, JA; Mayer, IA; Mukherjee, SD; Oja, CD; Parulekar, WR; Pritchard, KI; Rastogi, P; Shepherd, LE; Stambolic, V; Thompson, AM; Tonkin, KS; Whelan, TJ | 1 |
| Noureddin, M; Rinella, ME | 1 |
| Chen, L; Kong, W; Lu, M; Niu, X; Zeng, T | 1 |
| Zhang, T | 1 |
| Correale, J; Farez, MF; Negrotto, L | 1 |
| Hatakeyama, T; Kohno, T; Kojima, T; Konno, T; Saito, T; Satohisa, S; Shimada, H; Takahashi, S; Tsujiwaki, M | 1 |
| Firouzjaei, A; Li, GC; Liu, WX; Wang, N; Zhu, BM | 1 |
| Ida, S; Kaneko, R; Murata, K | 1 |
| Altbach, M; Chalasani, P; Chow, HH; Galons, JP; Martinez, JA; Roe, D; Stopeck, A; Thompson, PA; Thomson, CA; Villa-Guillen, DE | 1 |
| Amin, S; Farooq, R; Hayat Bhat, M; Majid, S; Malik, R; Wani, HA | 1 |
| Bogdański, P; Grzymisławska, M; Kargulewicz, A; Kręgielska-Narożna, M; Kujawska-Łuczak, M; Musialik, K; Swora-Cwynar, E; Szulińska, M | 1 |
| Broaddus, RR; Iglesias, D; Lu, KH; Munsell, MF; Ramondetta, L; Schmandt, R; Soliman, PT; Westin, SN; Yates, M; Zhang, Q | 1 |
| Goto, M; Hariya, N; Mochizuki, K; Osonoi, T; Saito, M | 1 |
| Li, H; Li, S; Wang, R; Zhang, JP | 1 |
| Abi Haidar, M; Berguio Vidotti, D; de Almeida, BC; de Jesus Simões, M; Prado Correia, LE; Silva, I | 1 |
| Cuddihy, R; Davies, MJ; Garvey, WT; Leiter, LA; List, J; Ren, J; Van Gaal, L; Vijapurkar, U | 1 |
| Akbar, A; Barengolts, E; Chlipala, G; Dugas, L; Eisenberg, Y; Green, SJ; Layden, BT; Reddivari, B | 1 |
| Bray, GA; Goldberg, RB; Marcovina, SM; Mather, KJ; Orchard, TJ; Perreault, L; Temprosa, M | 1 |
| Bakhtyukov, A; Bayunova, L; Derkach, K; Romanova, I; Shpakov, A; Zakharova, I; Zorina, I | 1 |
| Durgia, H; Kamalanathan, S; Kar, SS; Palui, R; Patil, M; Raj, H; Sahoo, J; Sridharan, K | 1 |
| Balestrieri, ML; Barbieri, M; D'Onofrio, N; De Feo, M; Galdiero, M; Loreni, F; Marfella, R; Mureddu, S; Paolisso, G; Portoghese, M; Rizzo, MR; Sardu, C; Scisciola, L; Signoriello, G; Torella, M | 1 |
| Bassols, J; Carreras-Badosa, G; de Zegher, F; Díaz-Roldán, F; Dorado-Ceballos, E; Ibáñez, L; López-Bermejo, A; Martínez-Calcerrada, JM; Mas-Parés, B; Osiniri, I; Prats-Puig, A; Xargay-Torrent, S | 1 |
| Akolekar, R; Charakida, M; Georgiopoulos, G; Nicolaides, K; Panagiotopoulou, O; Shehata, H; Simpson, J; Syngelaki, A | 1 |
| Bhat, GA; Ganie, MA; Rashid, A; Shah, ZA; Shaheen, F; Shrivastava, M; Wani, IA | 1 |
| Bansal, Y; Bishnoi, M; Kondepudi, KK; Kuhad, A; Medhi, B; Singh, DP; Singh, R; Sodhi, RK | 1 |
| Annie, L; Derkach, KV; Gurusubramanian, G; Jeremy, M; Roy, VK; Shpakov, AO | 1 |
| Amamou, A; Atmani, K; Bahlouli, W; Bôle-Feysot, C; Breton, J; Coëffier, M; Déchelotte, P; Ducrotté, P; Goichon, A; L'Huillier, C; Lelouard, M; Ribet, D; Salameh, E; Tirelle, P | 1 |
| Dai, C; Li, W; Li, Y; Liu, H; Liu, Y; Pan, Z; Su, M; Sun, L; Wei, Y; Yin, S; Yuan, Y; Zhao, C; Zheng, L | 1 |
| Aasen, T; Abdul Moin, NI; Abdul Wafi, S; Aboukameel, A; Abu-Bakar, N; Acharya, A; Ackermans, L; Adaramoye, O; Adarsh, KV; Adeosun, WA; Ahmad, NH; Ahmadi, F; Akanni, O; Akbar, M; Akbulak, RO; Akev, N; Akkaya, Ö; Al-Rashed, S; AlAbbad, S; Alabi, O; Alappat, BJ; Alcalá, S; Alcoutlabi, M; Aleppo, G; Alexander Ross, JB; Alexander, JH; Alexander, R; Alias, A; Alimba, C; Alken, FA; Allan, R; Alpers, M; Alsbou, EM; Amarasiri, SS; An, T; Anastasiadis, F; Anastassiadou, M; Anderson, KC; Andronikos, P; Anheyer, D; Annapurna, K; Anorlu, RI; Anten, MM; Anthopoulos, TD; Araujo-Castillo, RV; Aravamudhan, S; Arawwawala, LDAM; Arulsamy, N; Arunamata, A; Asghar, A; Asiri, AM; Aslanidou, T; Astrakhantseva, IV; Astutik, E; Attanayake, AP; Atwater, BD; Audureau, E; Augusto, S; Bakare, A; Banach, M; Bandelier, P; Banerjee, S; Barral, M; Bascuñán, J; Bates, FS; Bauer, NJC; Bayrak, BB; Beck, RW; Beckervordersantforth, J; Beeri, R; Begum, R; Beldi-Ferchiou, A; Bellingham, G; Ben-Tal, N; Bendib, I; Bergenstal, RM; Berger, MF; Bernasconi, G; Berry, S; Beuvon, F; Bi, WJ; Bi, Z; Bianconi, V; Bibi, I; Blank, BR; Bliemeister, E; Bobkowski, W; Bode, AM; Booth, CM; Bose, U; Boyd, K; Brancato, A; Brenmoehl, J; Brogi, E; Bronzo, P; Brooks, T; Brown, D; Brown, DN; Bruce, D; Buan, MEM; Bueno-Hernández, F; Bugielski, B; Bulavaitė, A; Buscagan, TM; Buxton, R; Caffaro, MM; Cai, Q; Cai, X; Cai, Y; Calhoun, P; Callander, N; Cambier, S; Camparo, P; Canales-Vargas, EJ; Canham, K; Cantu, J; Cao, J; Cao, JW; Cao, P; Cao, T; Cao, X; Caravella, BA; Carcadea, E; Carè, J; Carmichael, P; Carrasco Cabrera, L; Carteaux, G; Carvalho, PDS; Casarez, E; Cazorla, M; Celestrin, CP; Chakraborty, NK; Chan, B; Chandarlapaty, S; Chandgude, AL; Chang, CC; Chang, JH; Chang, X; Chang, Y; Chankhanittha, T; Chantanis, S; Chapovetsky, A; Chavan, S; Chen, B; Chen, D; Chen, F; Chen, G; Chen, H; Chen, J; Chen, K; Chen, KJ; Chen, KP; Chen, L; Chen, MA; Chen, Q; Chen, S; Chen, W; Chen, WF; Chen, X; Chen, Y; Cheng, D; Cheng, J; Cheng, Q; Cheon, GJ; Chiu, SC; Cho, CH; Cho, J; Choi, H; Choi, JS; Choi, YH; Christie, P; Chu, CH; Chu, Y; Chung, DH; Chung, F; Cline, JP; Cohen, A; Cohen, AD; Cohen, NJ; Comen, E; Compter, I; Cong, J; Cong, Z; Cooper, A; Cornud, F; Costa, C; Costa, S; Covey, A; Cowan, AM; Cramer, H; Cruz-Rivera, C; Cui, J; Cui, M; Cui, Y; Cui, YH; Culquichicón, C; Cushman, T; D'Auria, SJ; da Silva, J; Dalgediene, I; Danenberg, HD; Das, S; Dasgupta, K; Daubit, IM; de Oliveira, PD; de Prost, N; De Ruysscher, D; Dearman, K; Decato, D; Delfau-Larue, MH; Deng, L; Dhakate, SR; Dharuman, V; Di Costanzo, N; Dickler, MN; Dinehart, EE; Ding, D; Dinh, TK; Divya, KP; Djifack Tadongfack, T; Do, T; Domínguez-Roldan, R; Domínguez-Zambrano, E; Dömling, A; Donato, MD; Dong, JH; Dong, W; Dong, X; Dong, XR; Dong, Y; Dong, Z; Downs, M; Drutskaya, MS; Du, B; Du, F; Du, H; Du, L; Du, X; Duan, Z; Duangthip, D; Dunstand-Guzmán, E; Duong, F; Eckert, DJ; Edelhäuser, BAH; Eekers, DBP; Efendi, F; Efraimidis, P; Ehrenberg, H; Ehsanbakhsh, Z; Eickholt, C; Eksterowicz, J; El Mobadder, M; El-Araby, IE; El-Magd, MA; El-Tarabany, MS; Elgorban, AM; Engelmann, D; English, KL; Esfandiari, H; Eslami, B; Espinosa-Cuevas, A; Eswara, S; Faber, E; Fan, XH; Fan, Y; Fang, J; Fang, Z; Fantin, VR; Fei, P; Feng, G; Feng, H; Feng, J; Feng, X; Feng, XJ; Fennell, TR; Fernández-Moreira, V; Ferraz, ABF; Ferreras, KN; Flores, K; Flores-Pérez, I; Flox, C; Fluharty, FL; Fokouong Tchoffo, E; Folefack, GO; Foroutan, T; Fort, D; Fourati, S; Fousas, S; Frapard, T; Freguia, S; Friedman, DJ; Friedman, LS; Fu, D; Fu, Q; Fu, Y; Fujinami, S; Furihata, K; Gal, RL; Gan, H; Gao, C; Gao, F; Gao, R; Gao, SS; Gao, W; Gao, XC; Gao, Y; Gao, Z; Garozi, L; Ge, J; Georgiopoulos, A; Gerakiou, K; Ghazimirsaeed, SM; Ghazimirsaeed, ST; Gimeno, MC; Gjestad, R; Glurich, I; Goetchius, E; Goland, S; Goldstein, S; Gonçalves, CM; Gonçalves, H; Gong, Q; Gonzalez, D; Goplen, FK; Gorshkova, EN; Gotsman, I; Govindasamy, V; Granger, CB; Greco, L; Grigoriadou-Skouta, E; Grigoropoulos, P; Grivicich, I; Gromov, NV; Gruber, S; Grytczuk, M; Grzech-Leśniak, K; Gu, L; Gu, S; Gu, Z; Guadagnini, D; Guan, H; Guilliams, M; Guo, J; Guo, L; Gupta, A; Gupta, SK; Gurzu, S; Gutleb, AC; Haban, A; Hablitz, JJ; Hadisuyatmana, S; Hahn, S; Haiges, R; Hallal-Calleros, C; Hamed, M; Hammad, N; Hammer, N; Han, C; Hao, Y; Harnett, J; Has, EMM; Hassanpour, K; Hatzopoulos, D; Hawaldar, R; He, X; He, Y; He, YY; He, Z; Heberman, D; Heckl, D; Hegde, H; Henson, MA; Hernández-Velázquez, VM; Herrera, E; Hijazi, Z; Hirayama, K; Hirth, JM; Hoeben, A; Hohnloser, SH; Hong, M; Hood, K; Hoplock, LB; Hopman, WM; Horlbogen, LM; Hossein Rashidi, B; Hou, G; Hou, H; Hou, J; Hou, Y; Hu, J; Hu, W; Hu, X; Hua, W; Huang, G; Huang, H; Huang, J; Huang, T; Huang, W; Huang, Y; Huang, YD; Huang, Z; Hudis, CA; Hue, S; Huo, J; Hussain, M; Hvas, AM; Ichii, T; Ide Zeuna, J; Ilyas, S; Inoue, T; Iranzo, A; Irfan, M; Iwasa, Y; Iwashita, Y; Izgorodina, EI; J R, A; Jaber, WA; Jaborek, JR; Jacobus, SJ; Jadeja, SD; Jafarabadi, M; Jalan, D; Jamil, MI; Jarrah, S; Jarvis, D; Jayatilaka, KAPW; Jemal-Turki, A; Jeon, YK; Jeong, N; Jeong, SH; Jeong, SY; Jermy, M; Jhaveri, K; Ji, H; Ji, K; Ji, RY; Jiang, F; Jiang, J; Jiang, X; Jiang, Y; Jiao, Q; Jilani, K; Jiménez-Guerrero, P; Jin, L; Jo, YH; Johnson, JG; Johnson, ML; Jones, WS; Jose, S; Jularic, M; Jung, I; Jung, YJ; Jungen, C; Junttila, MR; Kache, S; Kahanovitch, U; Kalantzi, KI; Kallio, T; Kamnoedboon, P; Kang, CH; Kang, H; Kang, J; Kang, KW; Kapoor, P; Karmakar, D; Kartalis, A; Kauranen, P; Kazocina, A; Keikha, F; Keltai, M; Kershaw, SV; Kettani, M; Khalvati, S; Khandhar, S; Khosla, N; Kiely, CJ; Kim, CC; Kim, H; Kim, MJ; Kim, Y; Kim, YH; Kim, YT; Kimoto, E; Kiyu, A; Klatt, N; Kobayashi, M; Koh, J; Köhler, R; Kondadasula, SV; Kong, H; Kong, W; Kong, X; Kotidis, A; Kotwal, A; Kouvari, M; Kozhinov, AN; Kruger, D; Kuang, S; Kuang, Y; Kubota, M; Kuklik, P; Kumar, P; Kumar, SK; Kuo, YF; Kurup, SP; Kusuhara, H; Kuswanto, H; Lacouture, ME; Lambin, P; Lang, CC; Langroudi, FH; Lanman, RB; Larsen, OH; 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Yang, S; Yang, T; Yang, X; Yang, Y; Yao, H; Yao, Y; Yari, D; Yassin, MT; Ye, C; Ye, J; Ye, Q; Yildiz, EA; Ying, S; Yoon, H; Yu, D; Yu, K; Yu, N; Yu, PL; Yuan, C; Yuan, D; Yuan, LJ; Yuan, Z; Yuen, N; Zagatto, AM; Zakaria, Y; Zalewski, AM; Zamora, S; Zavorotinskaya, T; Zeid, JL; Zeinoun, T; Zeng, C; Zerby, HN; Zhan, X; Zhang, A; Zhang, D; Zhang, E; Zhang, F; Zhang, H; Zhang, J; Zhang, L; Zhang, M; Zhang, P; Zhang, Q; Zhang, QY; Zhang, RG; Zhang, S; Zhang, T; Zhang, X; Zhang, Y; Zhang, YY; Zhao, CK; Zhao, H; Zhao, J; Zhao, K; Zhao, Q; Zhao, S; Zhao, T; Zhao, XQ; Zhao, Y; Zhao, Z; Zheng, J; Zheng, L; Zheng, Y; Zhou, B; Zhou, G; Zhou, L; Zhou, T; Zhou, X; Zhu, C; Zhu, J; Zhu, Y; Zhu, ZQ; Zhuang, T; Zimmermannova, O; Zin, NNINM; Zisimos, K; Zoghebi, KA; Zonder, JA; Zou, C; Zwirner, J | 1 |
| Bakhtyukov, AA; Bayunova, LV; Derkach, KV; Shpakov, AO; Zorina, II | 1 |
| Doganyigit, Z; Kaymak, E; Okan, A; Silici, S; Soylu, M; Yakan, B | 1 |
| Alves, VS; de Moraes, AMP; de Oliveira, JC; Francisco, FA; Franco, CCDS; Malta, A; Martins, IP; Mathias, PCF; Matiusso, CCI; Miranda, RA; Moreira, VM; Pavanello, A; Prates, KV; Previate, C | 1 |
| Bednarski, M; Kieć-Kononowicz, K; Kotańska, M; Kuder, K; Mika, K; Pociecha, K; Pomierny, B; Sapa, J; Szafarz, M; Szczepańska, K | 1 |
| Bixo, M; Dehlin, E; Løvvik, TS; Molin, J; Vanky, E | 1 |
| Bakhtyukov, AA; Bayunova, LV; Derkach, KV; Morina, IY; Romanova, IV; Shpakov, AO; Sorokoumov, VN; Stepochkina, AM; Zakharova, IO | 1 |
| Daneshjou, D; Mehranjani, MS; Mofarahe, ZS; Shariatzadeh, SMA; Zadehmodarres, S | 1 |
| Dadashpour, M; Jafari-Gharabaghlou, D; Lotfi, F; Mousazadeh, H; Salmani Javan, E; Zarghami, N | 1 |
| Choi, SY; Jang, S; Kim, DG; Kim, J; Kim, S; Lee, CH; Lee, KW; Lee, N; Park, JK; Suh, SB | 1 |
| Nirwan, N; Vohora, D | 1 |
| Bai, X; Cai, D; Chen, J; Chen, T; Ding, C; Han, W; Huang, H; Li, D; Li, J; Ou, Q; Ruan, G; Tang, S; Wang, L; Zhang, Y; Zhao, Y; Zhu, Z | 1 |
| Huang, S; Kang, Y; Li, M; Liu, L; Xiao, Y | 1 |
| Alhassanin, SA; El-Attar, AA; Essa, ES; Ibrahim, OM; Mostafa, TM | 1 |
| Cao, T; Gao, L; Liu, B; Lu, L; Sui, Y; Xu, J; Yang, T; Zhu, S | 1 |
| Bixo, M; Molin, J; Vanky, E | 1 |
| Sumantri, IB; Syahputra, RA; Syarifah, S; Widyawati, T | 1 |
| Ababneh, E; Alfaqih, MA; Aljanabi, M; Alqudah, M; Khanfar, M; Sater, M | 1 |
| Koskensalo, K; Loo, BM; Niinikoski, H; Nikkinen, H; Paavilainen, E; Parkkola, R; Rönnemaa, T; Tertti, K; Tossavainen, P; Vääräsmäki, M; Veijola, R | 1 |
| Bacha, F; Barua, S; Ismail, HM; Libman, I; Nadeau, KJ; Redondo, MJ; Sabharwal, A; Tosur, M; Wang, J | 1 |
| Ahemaiti, A; Gulinuer, A; Liu, K; Tuernisaguli, K | 1 |
15 review(s) available for metformin and leptin
| Article | Year |
|---|---|
Clinical efficacy of metformin against insulin resistance parameters: sinking the iceberg.
Topics: Animals; Blood Glucose; Cardiovascular Diseases; Chromans; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Humans; Hyperinsulinism; Hypoglycemic Agents; Insulin; Insulin Resistance; Leptin; Male; Metformin; Rats; Risk Factors; Thiazoles; Thiazolidinediones; Troglitazone | 1999 |
Intensive therapies for pediatric obesity.
Topics: Adolescent; Appetite Depressants; Child; Diet, Reducing; Gastric Bypass; Gastrointestinal Agents; Humans; Hypoglycemic Agents; Leptin; Metformin; Obesity; Octreotide | 2001 |
Should patients with polycystic ovary syndrome be treated with metformin? Benefits of insulin sensitizing drugs in polycystic ovary syndrome--beyond ovulation induction.
Topics: Androgens; Cardiovascular Diseases; Female; Fertilization in Vitro; Gonadotropins; Humans; Hypoglycemic Agents; Infertility, Female; Insulin; Insulin Resistance; Leptin; Menstrual Cycle; Metformin; Ovulation Induction; Plasminogen Activator Inhibitor 1; Polycystic Ovary Syndrome | 2002 |
Expanding role of AMPK in endocrinology.
Topics: Adiponectin; AMP-Activated Protein Kinases; Animals; Appetite Regulation; Cannabinoids; Cytokines; Endocrine System; Fatty Acid Synthases; Ghrelin; Glucose; Humans; Hypothalamic Hormones; Insulin; Leptin; Metformin; Models, Biological; Multienzyme Complexes; Peptide Hormones; Protein Serine-Threonine Kinases; Receptors, Adrenergic; Resistin; Rosiglitazone; Thiazolidinediones; Thioctic Acid | 2006 |
Emerging concepts in the medical and surgical treatment of obesity.
Topics: Adipose Tissue; Amyloid; Anticonvulsants; Antidepressive Agents; Anxiety; Appetite Regulation; Bariatric Surgery; Body Mass Index; Bupropion; Cholecystokinin; Ciliary Neurotrophic Factor; Clinical Trials as Topic; Cyclobutanes; Depression; Diabetes Mellitus, Type 2; Female; Fluoxetine; Fructose; Ghrelin; Humans; Intra-Abdominal Fat; Islet Amyloid Polypeptide; Isoxazoles; Lactones; Leptin; Metabolic Syndrome; Metformin; Obesity; Obesity, Morbid; Orlistat; Oxyntomodulin; Peptide YY; Piperidines; Polycystic Ovary Syndrome; Pyrazoles; Rimonabant; Sertraline; Sleep Apnea, Obstructive; Surgical Procedures, Operative; Topiramate; Zonisamide | 2008 |
Pharmacotherapy for obesity.
Topics: Amyloid; Anti-Obesity Agents; Appetite Depressants; Body Weight; Chronic Disease; Comorbidity; Cyclobutanes; Exenatide; Gastrointestinal Hormones; Humans; Islet Amyloid Polypeptide; Lactones; Leptin; Metformin; Obesity; Orlistat; Peptides; Piperidines; Pyrazoles; Randomized Controlled Trials as Topic; Rimonabant; Venoms | 2007 |
AMP-activated protein kinase: a potential player in Alzheimer's disease.
Topics: Alzheimer Disease; AMP-Activated Protein Kinases; Amyloid; Animals; Autophagy; Calcium; Enzyme Activation; Humans; Inflammation; Leptin; Metformin; Neurons; Phosphorylation; tau Proteins | 2011 |
Adipokines in the HIV/HAART-associated lipodystrophy syndrome.
Topics: Adiponectin; Glucose Intolerance; HIV-Associated Lipodystrophy Syndrome; Humans; Leptin; Metformin; Thiazolidinediones | 2013 |
Use of non-insulin therapies for type 1 diabetes.
Topics: Allylamine; Animals; Blood Glucose; Bromocriptine; Cardiovascular Diseases; Colesevelam Hydrochloride; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Dipeptidyl-Peptidase IV Inhibitors; Gastrins; Glucagon-Like Peptide 1; Glycated Hemoglobin; Humans; Hypoglycemia; Hypoglycemic Agents; Islet Amyloid Polypeptide; Leptin; Metformin; Sodium-Glucose Transporter 1; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Sulfonylurea Compounds; Thiazolidinediones; United States | 2013 |
[Uncommon lipodystrophic syndromes].
Topics: Acro-Osteolysis; Adipose Tissue; Aging, Premature; Body Composition; Cardiovascular System; Combined Modality Therapy; Diabetes Mellitus; Diet, Carbohydrate-Restricted; Diet, Fat-Restricted; Erythema Nodosum; Fingers; Genes, Dominant; Humans; Hypoglycemic Agents; Insulin; Leptin; Lipodystrophy; Lipodystrophy, Familial Partial; Mandible; Metformin; Musculoskeletal Diseases; Phenotype; Recombinant Proteins; Surgery, Plastic; Werner Syndrome | 2015 |
Effects of metformin on weight loss: potential mechanisms.
Topics: Appetite Depressants; Diabetes Mellitus, Type 2; Eating; Humans; Hypoglycemic Agents; Hypothalamus; Insulin Resistance; Leptin; Metformin; Obesity; Risk Reduction Behavior; Signal Transduction; Treatment Outcome; Weight Loss | 2014 |
Nonalcoholic Fatty liver disease, diabetes, obesity, and hepatocellular carcinoma.
Topics: Carcinoma, Hepatocellular; Chemoprevention; Diabetes Mellitus, Type 2; Endoplasmic Reticulum Stress; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemic Agents; Incidence; Inflammation; Insulin Resistance; JNK Mitogen-Activated Protein Kinases; Leptin; Liver Neoplasms; Metformin; Non-alcoholic Fatty Liver Disease; Obesity; Risk Factors; S-Adenosylmethionine; Toll-Like Receptors | 2015 |
Impact of Treatment with Metformin on Adipocytokines in Patients with Polycystic Ovary Syndrome: A Meta-Analysis.
Topics: Adiponectin; Cytokines; Female; Gene Expression Regulation; Humans; Leptin; Metformin; Nicotinamide Phosphoribosyltransferase; Polycystic Ovary Syndrome; Resistin; Treatment Outcome | 2015 |
Effects of metformin treatment on blood leptin and ghrelin levels in patients with type 2 diabetes mellitus.
Topics: Diabetes Mellitus, Type 2; Ghrelin; Humans; Hypoglycemic Agents; Leptin; Metformin; Randomized Controlled Trials as Topic; Treatment Outcome | 2017 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acrylic Resins; Actinobacillus; Acute Disease; Acute Kidney Injury; Adaptor Proteins, Signal Transducing; Adenosine; Adenosine Triphosphate; Administration, Inhalation; Administration, Oral; Adolescent; Adult; Advance Care Planning; Africa, Northern; Age Factors; Aged; Aged, 80 and over; Air Pollutants; Air Pollution; Air Pollution, Indoor; Albendazole; Aluminum Oxide; Anastomosis, Surgical; Ancylostoma; Ancylostomiasis; Androstadienes; Angiogenesis Inhibitors; Angiotensin II; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Antibodies, Bispecific; Antibodies, Viral; Anticoagulants; Antihypertensive Agents; Antinematodal Agents; Antineoplastic Agents; Antineoplastic Agents, Immunological; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Antiporters; Antiviral Agents; Apoptosis; Aptamers, Nucleotide; Aromatase Inhibitors; Asian People; Astrocytes; Atrial Fibrillation; Auditory Threshold; Aurora Kinase B; Australia; Autophagy; Autophagy-Related Protein 5; Autotrophic Processes; Bacillus cereus; Bacillus thuringiensis; Bacterial Proteins; Beclin-1; Belgium; Benzene; Benzene Derivatives; Benzhydryl Compounds; beta Catenin; beta-Arrestin 2; Biliary Tract Diseases; Biofilms; Biofuels; Biomarkers; Biomarkers, Tumor; Biomass; Biomechanical Phenomena; Bioreactors; Biosensing Techniques; Biosynthetic Pathways; Bismuth; Blood Platelets; Bone and Bones; Bone Regeneration; Bortezomib; Botulinum Toxins, Type A; Brain; Brain Injuries; Brain Ischemia; Brain Neoplasms; Breast Neoplasms; Breath Tests; Bronchodilator Agents; Calcium Phosphates; Cannabis; Carbon Dioxide; Carbon Isotopes; Carcinogenesis; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cardiac Resynchronization Therapy; Cardiac Resynchronization Therapy Devices; Cardiomyopathies; Cardiovascular Diseases; Cariostatic Agents; Case Managers; Case-Control Studies; Catalysis; Cation Transport Proteins; CD8-Positive T-Lymphocytes; Cecropia Plant; Cell Adhesion; Cell Count; Cell Differentiation; Cell Division; Cell Line; Cell Line, Tumor; Cell Membrane; Cell Movement; Cell Proliferation; Cell Self Renewal; Cell Survival; Cells, Cultured; Cellular Reprogramming; Cellulose; Charcoal; Chemical and Drug Induced Liver Injury; Chemical Phenomena; Chemokines; Chemoradiotherapy; Chemoreceptor Cells; Child; Child Abuse; Child, Preschool; China; Chlorogenic Acid; Chloroquine; Chromatography, Gas; Chronic Disease; Clinical Competence; Coated Materials, Biocompatible; Cochlea; Cohort Studies; Color; Comorbidity; Computer Simulation; Computer-Aided Design; Contraception; Contraceptive Agents, Female; Contrast Media; COP-Coated Vesicles; Coronavirus Infections; Cost of Illness; Coturnix; COVID-19; Creatinine; Cross-Over Studies; Cross-Sectional Studies; Culex; Curriculum; Cyclic N-Oxides; Cytokines; Cytoplasm; Cytotoxicity, Immunologic; Cytotoxins; Databases, Factual; Deep Learning; 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Skull Fractures; Social Determinants of Health; Sodium; Sodium Fluoride; Sodium Potassium Chloride Symporter Inhibitors; Sodium-Glucose Transporter 2 Inhibitors; Soil; Soil Pollutants; Spain; Spectrophotometry; Spectroscopy, Fourier Transform Infrared; Staphylococcal Protein A; Staphylococcus aureus; Stem Cells; Stereoisomerism; Stomach Neoplasms; Streptomyces; Strontium; Structure-Activity Relationship; Students, Nursing; Substance-Related Disorders; Succinic Acid; Sulfur; Surface Properties; Survival Rate; Survivin; Symporters; T-Lymphocytes; Temozolomide; Tensile Strength; Thiazoles; Thiobacillus; Thiohydantoins; Thiourea; Thrombectomy; Time Factors; Titanium; Tobacco Mosaic Virus; Tobacco Use Disorder; Toll-Like Receptor 4; Toluene; Tomography, X-Ray Computed; TOR Serine-Threonine Kinases; Toxicity Tests, Acute; Toxicity Tests, Subacute; Transcriptional Activation; Treatment Outcome; Troponin I; Tumor Cells, Cultured; Tumor Escape; Tumor Hypoxia; Tumor Microenvironment; Tumor Necrosis Factor Inhibitors; Tumor Necrosis Factor-alpha; Tyrosine; Ubiquitin-Protein Ligases; Ubiquitination; Ultrasonic Waves; United Kingdom; United States; United States Department of Veterans Affairs; Up-Regulation; Urea; Uric Acid; Urinary Bladder Neoplasms; Urinary Bladder, Neurogenic; Urine; Urodynamics; User-Computer Interface; Vemurafenib; Verbenaceae; Veterans; Veterans Health; Viral Load; Virtual Reality; Vitiligo; Water Pollutants, Chemical; Wildfires; Wnt Signaling Pathway; Wound Healing; X-Ray Diffraction; Xenograft Model Antitumor Assays; Xylenes; Young Adult; Zinc; Zinc Oxide; Zinc Sulfate; Zoonoses | 2021 |
50 trial(s) available for metformin and leptin
| Article | Year |
|---|---|
Decreased serum leptin concentrations during metformin therapy in obese women with polycystic ovary syndrome.
Topics: Adult; Analysis of Variance; Drug Administration Schedule; Female; Humans; Hypoglycemic Agents; Leptin; Metformin; Obesity; Polycystic Ovary Syndrome; Proteins | 1998 |
Effect of long-term treatment with metformin added to hypocaloric diet on body composition, fat distribution, and androgen and insulin levels in abdominally obese women with and without the polycystic ovary syndrome.
Topics: Abdomen; Adipose Tissue; Adult; Androgens; Body Composition; Combined Modality Therapy; Diet, Reducing; Double-Blind Method; Estradiol; Female; Follicle Stimulating Hormone; Humans; Hypoglycemic Agents; Insulin; Leptin; Luteinizing Hormone; Metformin; Obesity; Placebos; Polycystic Ovary Syndrome; Progesterone; Sex Hormone-Binding Globulin; Viscera | 2000 |
Effect of metformin on glucagon-like peptide 1 (GLP-1) and leptin levels in obese nondiabetic subjects.
Topics: Adolescent; Adult; Blood Glucose; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose Clamp Technique; Humans; Hypoglycemic Agents; Leptin; Male; Metformin; Middle Aged; Obesity; Peptide Fragments; Peptides | 2001 |
Insulin, leptin, IGF-I and insulin-dependent protein concentrations after insulin-sensitizing therapy in obese women with polycystic ovary syndrome.
Topics: Adult; Blood Glucose; Diet, Reducing; Female; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulin-Like Growth Factor Binding Protein 1; Insulin-Like Growth Factor I; Leptin; Metformin; Obesity; Polycystic Ovary Syndrome | 2001 |
The effects of metformin on body mass index and glucose tolerance in obese adolescents with fasting hyperinsulinemia and a family history of type 2 diabetes.
Topics: Adolescent; Blood Glucose; Body Mass Index; Body Weight; Child; Comorbidity; Diabetes Mellitus; Diabetes Mellitus, Type 2; Family; Female; Glucose Tolerance Test; Humans; Hyperinsulinism; Hypoglycemic Agents; Insulin; Leptin; Male; Metformin; Obesity; Pilot Projects | 2001 |
Beneficial effects of metformin in normoglycemic morbidly obese adolescents.
Topics: Adipose Tissue; Adolescent; Blood Glucose; Body Composition; Body Mass Index; Cholesterol; Diet, Reducing; Double-Blind Method; Energy Intake; Fasting; Fatty Acids, Nonesterified; Female; Glucose Tolerance Test; Humans; Hyperinsulinism; Hypoglycemic Agents; Kinetics; Leptin; Male; Metformin; Obesity, Morbid; Placebos; Triglycerides; Weight Loss | 2001 |
Short-term treatment with metformin decreases serum leptin concentration without affecting body weight and body fat content in normal-weight healthy men.
Topics: Adipose Tissue; Adult; Blood Pressure; Body Weight; C-Peptide; Diabetes Mellitus; Glucagon; Humans; Hydrocortisone; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulin-Like Growth Factor Binding Protein 3; Insulin-Like Growth Factor I; Leptin; Male; Metformin; Obesity; Reference Values | 2002 |
Modulation of hunger by plasma glucose and metformin.
Topics: Adult; Blood Glucose; Cross-Over Studies; Double-Blind Method; Glucose Clamp Technique; Humans; Hunger; Hypoglycemic Agents; Insulin; Leptin; Male; Metformin | 2003 |
Leptin and body fat in type 2 diabetes and monodrug therapy.
Topics: Adipose Tissue; Body Composition; Body Mass Index; Cholesterol, HDL; Cross-Over Studies; Diabetes Mellitus, Type 2; Fatty Acids, Nonesterified; Female; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin; Insulin Secretion; Leptin; Male; Metformin; Middle Aged | 2003 |
Metformin ameliorates treatment of obese type 2 diabetic patients with mental retardation; its effects on eating behavior and serum leptin levels.
Topics: Adult; Blood Glucose; Body Mass Index; Cholesterol; Diabetes Mellitus, Type 2; Energy Intake; Feeding Behavior; Female; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin; Intellectual Disability; Leptin; Male; Metformin; Obesity; Surveys and Questionnaires; Treatment Outcome; Triglycerides | 2004 |
Adiponectin and C-reactive protein in obesity, type 2 diabetes, and monodrug therapy.
Topics: Adiponectin; Blood Glucose; Body Composition; C-Reactive Protein; Cross-Over Studies; Diabetes Mellitus, Type 2; Female; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Intercellular Signaling Peptides and Proteins; Leptin; Linear Models; Lipids; Male; Metformin; Middle Aged; Obesity; Sex Factors | 2004 |
Are the beneficial cardiovascular effects of simvastatin and metformin also associated with a hormone-dependent mechanism improving insulin sensitivity?
Topics: Adiponectin; Adolescent; Adult; Aged; Anticholesteremic Agents; Body Mass Index; C-Reactive Protein; Cardiovascular Diseases; Female; Humans; Hypoglycemic Agents; Leptin; Male; Metabolic Syndrome; Metformin; Middle Aged; Simvastatin | 2007 |
Insulin counter-regulatory factors, fibrinogen and C-reactive protein during olanzapine administration: effects of the antidiabetic metformin.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Blood Glucose; C-Reactive Protein; Double-Blind Method; Female; Fibrinogen; Glucagon; Human Growth Hormone; Humans; Hydrocortisone; Hypoglycemic Agents; Insulin; Insulin Resistance; Leptin; Male; Metabolic Syndrome; Metformin; Middle Aged; Olanzapine; Schizophrenia; Sex Factors; Treatment Outcome; Tumor Necrosis Factor-alpha | 2007 |
Metformin as an adjunctive treatment to control body weight and metabolic dysfunction during olanzapine administration: a multicentric, double-blind, placebo-controlled trial.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Blood Glucose; Body Mass Index; Body Weight; Brief Psychiatric Rating Scale; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Energy Metabolism; Female; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin Resistance; Leptin; Lipids; Male; Metformin; Middle Aged; Olanzapine; Schizophrenia; Statistics as Topic | 2007 |
Metformin treatment does not affect total leptin levels and free leptin index in obese patients with polycystic ovary syndrome.
Topics: Adult; Female; Humans; Hyperinsulinism; Hypoglycemic Agents; Insulin; Leptin; Metformin; Obesity; Polycystic Ovary Syndrome | 2008 |
Alteration of ghrelin-neuropeptide Y network in obese patients with polycystic ovary syndrome: role of hyperinsulinism.
Topics: Adult; Female; Ghrelin; Glucose Tolerance Test; Humans; Hyperinsulinism; Hypoglycemic Agents; Insulin; Leptin; Metformin; Neuropeptide Y; Obesity; Pilot Projects; Polycystic Ovary Syndrome; Signal Transduction; Young Adult | 2008 |
Rosiglitazone therapy improves insulin resistance parameters in overweight and obese diabetic patients intolerant to metformin.
Topics: Adiponectin; Diabetes Mellitus, Type 2; Female; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Italy; Leptin; Male; Metformin; Middle Aged; Obesity; Overweight; Resistin; Rosiglitazone; Single-Blind Method; Thiazolidinediones; Tumor Necrosis Factor-alpha | 2008 |
The effect of metformin on leptin in obese patients with type 2 diabetes mellitus and nonalcoholic fatty liver disease.
Topics: Adult; Body Mass Index; Diabetes Mellitus, Type 2; Exercise; Fatty Liver; Female; Glycated Hemoglobin; Humans; Hypertension; Hypoglycemic Agents; Insulin; Insulin Resistance; Leptin; Life Style; Lipoproteins; Liver Function Tests; Male; Metformin; Middle Aged; Obesity; Triglycerides | 2009 |
Antiandrogenic contraceptives increase serum adiponectin in obese polycystic ovary syndrome patients.
Topics: Adipocytes; Adiponectin; Adipose Tissue; Adult; Androgen Antagonists; Area Under Curve; Body Weight; Contraceptives, Oral; Dehydroepiandrosterone Sulfate; Female; Humans; Insulin; Leptin; Metformin; Obesity; Polycystic Ovary Syndrome; Testosterone; Young Adult | 2009 |
Extended release metformin for metabolic control assistance during prolonged clozapine administration: a 14 week, double-blind, parallel group, placebo-controlled study.
Topics: Adult; Anthropometry; Antipsychotic Agents; Blood Glucose; Blood Pressure; Body Mass Index; Body Weight; Cholesterol, HDL; Clozapine; Double-Blind Method; Drug Delivery Systems; Enzyme-Linked Immunosorbent Assay; Female; Follow-Up Studies; Humans; Hydrocortisone; Hypoglycemic Agents; Insulin; Insulin Resistance; Leptin; Male; Metformin; Middle Aged; Schizophrenia; Statistics, Nonparametric; Waist Circumference | 2009 |
Pubertal metformin therapy to reduce total, visceral, and hepatic adiposity.
Topics: Adiposity; Adolescent; Body Weight; Child; Comorbidity; Female; Follow-Up Studies; Humans; Hyperinsulinism; Hypoglycemic Agents; Infant, Low Birth Weight; Infant, Newborn; Intra-Abdominal Fat; Leptin; Liver; Magnetic Resonance Imaging; Metformin; Puberty, Precocious | 2010 |
Novel inflammatory markers in overweight women with and without polycystic ovary syndrome and following pharmacological intervention.
Topics: Adiponectin; Adiposity; Aldosterone; Biomarkers; Body Mass Index; Cross-Sectional Studies; Female; Humans; Hypoglycemic Agents; Leptin; Metformin; Overweight; Polycystic Ovary Syndrome; Pregnancy | 2010 |
Comparison of the effects of sibutramine versus sibutramine plus metformin in obese women.
Topics: Adult; Appetite Depressants; C-Reactive Protein; Cyclobutanes; Drug Therapy, Combination; Female; Humans; Insulin Resistance; Leptin; Metformin; Middle Aged; Obesity; Treatment Outcome; Weight Loss | 2010 |
Leptin concentrations in patients with polycystic ovary syndrome before and after met-formin treatment depending on insulin resistance, body mass index and androgen con-centrations--introductory report.
Topics: Androgens; Body Mass Index; Female; Humans; Hypoglycemic Agents; Insulin Resistance; Leptin; Metformin; Polycystic Ovary Syndrome | 2009 |
Polymorphisms of the LEP- and LEPR genes, metabolic profile after prolonged clozapine administration and response to the antidiabetic metformin.
Topics: Adult; Antipsychotic Agents; Blood Glucose; Body Mass Index; Clozapine; Double-Blind Method; Female; Genotype; Humans; Hydrocortisone; Hypoglycemic Agents; Insulin Resistance; Leptin; Male; Metabolic Diseases; Metformin; Middle Aged; Pharmacogenetics; Polymorphism, Single Nucleotide; Receptors, Leptin; Schizophrenia; Venezuela | 2010 |
Metformin restores the correlation between serum-oxidized LDL and leptin levels in type 2 diabetic patients.
Topics: Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Humans; Leptin; Lipoproteins, LDL; Male; Metformin; Middle Aged; Oxidative Stress | 2011 |
Metformin decreases plasma resistin concentrations in pediatric patients with impaired glucose tolerance: a placebo-controlled randomized clinical trial.
Topics: Adiponectin; Adolescent; Biomarkers; C-Reactive Protein; Child; Child, Preschool; Drug Administration Schedule; Energy Intake; Exercise; Female; Glucose Intolerance; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Inflammation; Interleukin-1beta; Interleukin-6; Leptin; Male; Metformin; Resistin; Tumor Necrosis Factor-alpha; Weight Loss | 2012 |
Ethinyl estradiol-cyproterone acetate versus low-dose pioglitazone-flutamide-metformin for adolescent girls with androgen excess: divergent effects on CD163, TWEAK receptor, ANGPTL4, and LEPTIN expression in subcutaneous adipose tissue.
Topics: Abdominal Fat; Adolescent; Androgen Antagonists; Angiopoietin-Like Protein 4; Angiopoietins; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Body Composition; Cyproterone Acetate; Dose-Response Relationship, Drug; Drug Combinations; Ethinyl Estradiol; Female; Flutamide; Gene Expression; Humans; Hyperandrogenism; Hypoglycemic Agents; Leptin; Metformin; Pioglitazone; Receptors, Cell Surface; Receptors, Tumor Necrosis Factor; Subcutaneous Fat; Thiazolidinediones; TWEAK Receptor | 2012 |
Maternal and neonatal circulating markers of metabolic and cardiovascular risk in the metformin in gestational diabetes (MiG) trial: responses to maternal metformin versus insulin treatment.
Topics: Adult; Blood Glucose; C-Peptide; C-Reactive Protein; Cardiovascular Diseases; Cholesterol, HDL; Diabetes, Gestational; Female; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Infant, Newborn; Insulin; Leptin; Metformin; Pregnancy; Risk Factors; Triglycerides | 2013 |
Treatment with pioglitazone is associated with decreased preprandial ghrelin levels: a randomized clinical trial.
Topics: Adult; Blood Glucose; Body Weight; Diabetes Mellitus, Type 2; Female; Ghrelin; Glucose Tolerance Test; Humans; Insulin; Leptin; Male; Metformin; Middle Aged; Pioglitazone; Thiazolidinediones | 2013 |
Comparative effects of metformin and pioglitazone on omentin and leptin concentrations in patients with newly diagnosed diabetes: a randomized clinical trial.
Topics: Adult; Aged; Blood Glucose; Cytokines; Diabetes Mellitus, Type 2; Female; GPI-Linked Proteins; Humans; Hypoglycemic Agents; Lectins; Leptin; Male; Metformin; Middle Aged; Pioglitazone; Thiazolidinediones | 2013 |
The effects of drospirenone-ethinyl estradiol and drospirenone-ethinyl estradiol + metformin on ovarian ultrasonographic markers, body fat mass index, leptin, and ghrelin.
Topics: Abdominal Fat; Adiposity; Adolescent; Adult; Androstenes; Body Mass Index; Drug Therapy, Combination; Ethinyl Estradiol; Female; Ghrelin; Humans; Leptin; Metformin; Organ Size; Ovarian Follicle; Ovary; Polycystic Ovary Syndrome; Reproductive Control Agents; Ultrasonography; Young Adult | 2013 |
The lost correlation between leptin and CRP in type 2 diabetes.
Topics: C-Reactive Protein; Case-Control Studies; Demography; Diabetes Mellitus, Type 2; Humans; Hypoglycemic Agents; Leptin; Linear Models; Metformin; Middle Aged | 2013 |
Presurgical trial of metformin in overweight and obese patients with newly diagnosed breast cancer.
Topics: Aged; Antineoplastic Agents; Biomarkers, Tumor; Body Mass Index; Breast Neoplasms; Cell Proliferation; Chemotherapy, Adjuvant; Cholesterol; Drug Administration Schedule; Female; Humans; Leptin; Metformin; Middle Aged; Neoplasm Staging; New York City; Obesity; Overweight; Time Factors; Treatment Outcome | 2014 |
Effect of metformin vs placebo on and metabolic factors in NCIC CTG MA.32.
Topics: Adult; Aged; Blood Glucose; Body Mass Index; Breast Neoplasms; C-Reactive Protein; Combined Modality Therapy; Disease-Free Survival; Female; Humans; Hypoglycemic Agents; Insulin; Leptin; Metformin; Middle Aged; Neoplasm Staging; North America; Research Design; Statistics, Nonparametric; Switzerland; United Kingdom | 2015 |
[Effect of Qingre Yangyin Recipe on Endocrine and Metabolism of Polycystic Ovary Syndrome Patients].
Topics: Adiponectin; Blood Glucose; Body Mass Index; Drugs, Chinese Herbal; Estradiol; Female; Follicle Stimulating Hormone; Gonadal Steroid Hormones; Humans; Insulin; Insulin Resistance; Leptin; Luteinizing Hormone; Metformin; Polycystic Ovary Syndrome; Progesterone; Prolactin; Testosterone | 2015 |
Comparative evaluation of the therapeutic effect of metformin monotherapy with metformin and acupuncture combined therapy on weight loss and insulin sensitivity in diabetic patients.
Topics: Acupuncture Therapy; Adiponectin; Adult; Biomarkers; Body Mass Index; Body Weight; Cholesterol, HDL; Cholesterol, LDL; Diabetes Mellitus, Type 2; Fatty Acids, Nonesterified; Female; Glucagon-Like Peptide 1; Humans; Insulin; Insulin Resistance; Interleukin-6; Leptin; Male; Metformin; Obesity; Resistin; Serotonin; Triglycerides; Tumor Necrosis Factor-alpha; Weight Loss | 2016 |
Phase II study of metformin for reduction of obesity-associated breast cancer risk: a randomized controlled trial protocol.
Topics: Adiponectin; Adult; Body Weight; Breast; Breast Neoplasms; Double-Blind Method; Humans; Hypoglycemic Agents; Insulin; Insulin-Like Growth Factor Binding Protein 3; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Leptin; Magnetic Resonance Imaging; Metformin; Middle Aged; Obesity; Outcome Assessment, Health Care; Risk Factors; Testosterone; Waist Circumference | 2016 |
Improvement of serum adiponectin and leptin concentrations: effects of a low-calorie or isocaloric diet combined with metformin or orlistat - a prospective randomized open-label trial.
Topics: Adiponectin; Aged; Caloric Restriction; Diet, Reducing; Female; Humans; Hypoglycemic Agents; Lactones; Leptin; Metformin; Middle Aged; Obesity; Orlistat; Postmenopause; Prospective Studies; Weight Loss | 2016 |
Add-on therapy with anagliptin in Japanese patients with type-2 diabetes mellitus treated with metformin and miglitol can maintain higher concentrations of biologically active GLP-1/total GIP and a lower concentration of leptin.
Topics: 1-Deoxynojirimycin; Aged; Blood Glucose; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Gastric Inhibitory Polypeptide; Glucagon-Like Peptide 1; Humans; Hypoglycemic Agents; Leptin; Male; Metformin; Middle Aged; Pyrimidines; Treatment Outcome | 2016 |
Effects of canagliflozin versus glimepiride on adipokines and inflammatory biomarkers in type 2 diabetes.
Topics: Adiponectin; Aged; Biomarkers; Blood Glucose; C-Reactive Protein; Canagliflozin; Diabetes Mellitus, Type 2; Double-Blind Method; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Inflammation; Leptin; Male; Metformin; Middle Aged; Molybdoferredoxin; Sodium-Glucose Transporter 2 Inhibitors; Sulfonylurea Compounds; Treatment Outcome; Tumor Necrosis Factor-alpha | 2018 |
Gut microbiota varies by opioid use, circulating leptin and oxytocin in African American men with diabetes and high burden of chronic disease.
Topics: Bacteria; Black or African American; Chronic Disease; Cost of Illness; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Gastrointestinal Microbiome; Humans; Leptin; Male; Metformin; Opioid-Related Disorders; Oxytocin | 2018 |
Non-traditional biomarkers and incident diabetes in the Diabetes Prevention Program: comparative effects of lifestyle and metformin interventions.
Topics: Adiponectin; Biomarkers; Chemokine CCL2; Diabetes Mellitus; E-Selectin; Fibrinogen; Hypoglycemic Agents; Intercellular Adhesion Molecule-1; Interleukin-6; Leptin; Life Style; Metformin; Tissue Plasminogen Activator | 2019 |
Effect of metformin on thyroid function tests in patients with subclinical hypothyroidism: an open-label randomised controlled trial.
Topics: Adiponectin; Adult; Blood Glucose; Cholesterol; Female; Humans; Hypothyroidism; Insulin Resistance; Leptin; Male; Metformin; Middle Aged; Prolactin; Thyroid Function Tests; Thyrotropin; Thyroxine; Triiodothyronine | 2019 |
Effects of metformin administration on endocrine-metabolic parameters, visceral adiposity and cardiovascular risk factors in children with obesity and risk markers for metabolic syndrome: A pilot study.
Topics: Adolescent; Body Mass Index; Body Weight; C-Reactive Protein; Carotid Intima-Media Thickness; Child; Double-Blind Method; Female; Humans; Hyperinsulinism; Insulin; Leptin; Male; Metabolic Syndrome; Metformin; Obesity; Pilot Projects; Spain; White People | 2019 |
Metformin use in obese mothers is associated with improved cardiovascular profile in the offspring.
Topics: Adiponectin; Adult; Arterial Pressure; Blood Pressure; Body Composition; Child, Preschool; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Echocardiography; Female; Follow-Up Studies; Hemodynamics; Humans; Hypoglycemic Agents; Leptin; Male; Metformin; Obesity, Maternal; Pregnancy; Prenatal Exposure Delayed Effects; Pulse Wave Analysis; Triglycerides; Vascular Stiffness | 2020 |
Differential Impact of Insulin Sensitizers vs. Anti-Androgen on Serum Leptin Levels in Vitamin D Replete PCOS Women: A Six Month Open Labeled Randomized Study.
Topics: Adult; Blood Glucose; Female; Humans; Insulin; Insulin Resistance; Leptin; Metformin; Pioglitazone; Polycystic Ovary Syndrome; Spironolactone; Testosterone; Vitamin D; Young Adult | 2020 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acrylic Resins; Actinobacillus; Acute Disease; Acute Kidney Injury; Adaptor Proteins, Signal Transducing; Adenosine; Adenosine Triphosphate; Administration, Inhalation; Administration, Oral; Adolescent; Adult; Advance Care Planning; Africa, Northern; Age Factors; Aged; Aged, 80 and over; Air Pollutants; Air Pollution; Air Pollution, Indoor; Albendazole; Aluminum Oxide; Anastomosis, Surgical; Ancylostoma; Ancylostomiasis; Androstadienes; Angiogenesis Inhibitors; Angiotensin II; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Antibodies, Bispecific; Antibodies, Viral; Anticoagulants; Antihypertensive Agents; Antinematodal Agents; Antineoplastic Agents; Antineoplastic Agents, Immunological; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Antiporters; Antiviral Agents; Apoptosis; Aptamers, Nucleotide; Aromatase Inhibitors; Asian People; Astrocytes; Atrial Fibrillation; Auditory Threshold; Aurora Kinase B; Australia; Autophagy; Autophagy-Related Protein 5; Autotrophic Processes; Bacillus cereus; Bacillus thuringiensis; Bacterial Proteins; Beclin-1; Belgium; Benzene; Benzene Derivatives; Benzhydryl Compounds; beta Catenin; beta-Arrestin 2; Biliary Tract Diseases; Biofilms; Biofuels; Biomarkers; Biomarkers, Tumor; Biomass; Biomechanical Phenomena; Bioreactors; Biosensing Techniques; Biosynthetic Pathways; Bismuth; Blood Platelets; Bone and Bones; Bone Regeneration; Bortezomib; Botulinum Toxins, Type A; Brain; Brain Injuries; Brain Ischemia; Brain Neoplasms; Breast Neoplasms; Breath Tests; Bronchodilator Agents; Calcium Phosphates; Cannabis; Carbon Dioxide; Carbon Isotopes; Carcinogenesis; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cardiac Resynchronization Therapy; Cardiac Resynchronization Therapy Devices; Cardiomyopathies; Cardiovascular Diseases; Cariostatic Agents; Case Managers; Case-Control Studies; Catalysis; Cation Transport Proteins; CD8-Positive T-Lymphocytes; Cecropia Plant; Cell Adhesion; Cell Count; Cell Differentiation; Cell Division; Cell Line; Cell Line, Tumor; Cell Membrane; Cell Movement; Cell Proliferation; Cell Self Renewal; Cell Survival; Cells, Cultured; Cellular Reprogramming; Cellulose; Charcoal; Chemical and Drug Induced Liver Injury; Chemical Phenomena; Chemokines; Chemoradiotherapy; Chemoreceptor Cells; Child; Child Abuse; Child, Preschool; China; Chlorogenic Acid; Chloroquine; Chromatography, Gas; Chronic Disease; Clinical Competence; Coated Materials, Biocompatible; Cochlea; Cohort Studies; Color; Comorbidity; Computer Simulation; Computer-Aided Design; Contraception; Contraceptive Agents, Female; Contrast Media; COP-Coated Vesicles; Coronavirus Infections; Cost of Illness; Coturnix; COVID-19; Creatinine; Cross-Over Studies; Cross-Sectional Studies; Culex; Curriculum; Cyclic N-Oxides; Cytokines; Cytoplasm; Cytotoxicity, Immunologic; Cytotoxins; Databases, Factual; Deep Learning; Delivery, Obstetric; Denitrification; Dental Caries; Denture, Complete; Dexamethasone; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dielectric Spectroscopy; Diet, High-Fat; Dietary Fiber; Disease Models, Animal; Disease Progression; DNA; DNA Copy Number Variations; DNA, Mitochondrial; Dog Diseases; Dogs; Dopaminergic Neurons; Double-Blind Method; Down-Regulation; Doxorubicin; Drug Carriers; Drug Design; Drug Interactions; Drug Resistance, Bacterial; Drug Resistance, Neoplasm; Drug-Related Side Effects and Adverse Reactions; Drugs, Chinese Herbal; Dry Powder Inhalers; Dust; E2F1 Transcription Factor; Ecosystem; Education, Nursing; Education, Nursing, Baccalaureate; Electric Impedance; Electricity; Electrocardiography; Electrochemical Techniques; Electrochemistry; Electrodes; Electrophoresis, Polyacrylamide Gel; Endoplasmic Reticulum; Endothelial Cells; Environmental Monitoring; Enzyme Inhibitors; Epithelial Cells; Epithelial-Mesenchymal Transition; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Estrogen Receptor Modulators; Europe; Evoked Potentials, Auditory, Brain Stem; Exosomes; Feasibility Studies; Female; Ferricyanides; Ferrocyanides; Fibrinogen; Finite Element Analysis; Fistula; Fluorescent Dyes; Fluorides, Topical; Fluorodeoxyglucose F18; Fluticasone; Follow-Up Studies; Food Contamination; Food Microbiology; Foods, Specialized; Forensic Medicine; Frail Elderly; France; Free Radicals; Fresh Water; Fungi; Fungicides, Industrial; Galactosamine; Gastrointestinal Neoplasms; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Frequency; Genetic Predisposition to Disease; Genotype; Gingival Hemorrhage; Glioblastoma; Glioma; Glomerular Filtration Rate; Glomerulosclerosis, Focal Segmental; Glucose; Glucose Transport Proteins, Facilitative; Glucosides; Glutamine; Glycolysis; Gold; GPI-Linked Proteins; Gram-Negative Bacteria; Gram-Positive Bacteria; Graphite; Haplotypes; HCT116 Cells; Healthy Volunteers; Hearing Loss; Heart Failure; Hedgehog Proteins; HEK293 Cells; HeLa Cells; Hemodynamics; Hemorrhage; Hepatocytes; Hippo Signaling Pathway; Histone Deacetylases; Homeostasis; Hospital Mortality; Hospitalization; Humans; Hydantoins; Hydrazines; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Hydroxylamines; Hypoglycemic Agents; Immunity, Innate; Immunoglobulin G; Immunohistochemistry; Immunologic Factors; Immunomodulation; Immunophenotyping; Immunotherapy; Incidence; Indazoles; Indonesia; Infant; Infant, Newborn; Infarction, Middle Cerebral Artery; Inflammation; Injections, Intramuscular; Insecticides; Insulin-Like Growth Factor I; Insurance, Health; Intention to Treat Analysis; Interleukin-1 Receptor-Associated Kinases; Interleukin-6; Intrauterine Devices; Intrauterine Devices, Copper; Iron; Ischemia; Jordan; Keratinocytes; Kidney; Kidney Diseases; Kir5.1 Channel; Klebsiella Infections; Klebsiella pneumoniae; Lab-On-A-Chip Devices; Laparoscopy; Lasers; Lasers, Semiconductor; Lenalidomide; Leptin; Lethal Dose 50; Levonorgestrel; Limit of Detection; Lipid Metabolism; Lipid Metabolism Disorders; Lipogenesis; Lipopolysaccharides; Liquid Biopsy; Liver; Liver Abscess, Pyogenic; Liver Cirrhosis; Liver Diseases; Liver Neoplasms; Longevity; Lung Neoplasms; Luteolin; Lymph Nodes; Lymphocyte Activation; Macaca fascicularis; Macrophages; Mad2 Proteins; Magnetic Resonance Imaging; Male; Mammary Glands, Human; Manganese; Manganese Compounds; MAP Kinase Signaling System; Materials Testing; Maternal Health Services; MCF-7 Cells; Medicaid; Medicine, Chinese Traditional; Melanoma; Membrane Proteins; Mental Health; Mercury; Metal Nanoparticles; Metals, Heavy; Metformin; Methionine Adenosyltransferase; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Knockout; Mice, Nude; Microalgae; Microbial Sensitivity Tests; Microglia; MicroRNAs; Microscopy, Atomic Force; Microscopy, Electron, Scanning; Middle Aged; Mitochondria; Mitochondrial Proteins; Mitral Valve; Mitral Valve Insufficiency; Models, Anatomic; Molecular Structure; Molybdenum; Monocarboxylic Acid Transporters; Moths; MPTP Poisoning; Multigene Family; Multiparametric Magnetic Resonance Imaging; Multiple Myeloma; Muscle, Skeletal; Mutagens; Mutation; Myeloid Cells; Nanocomposites; Nanofibers; Nanomedicine; Nanoparticles; Nanowires; Neoadjuvant Therapy; Neomycin; Neoplasm Grading; Neoplasm Recurrence, Local; Neoplasms; Neoplastic Stem Cells; Neostriatum; Neovascularization, Pathologic; Netherlands; Neuromuscular Agents; Neurons; NF-E2-Related Factor 2; NF-kappa B; Nickel; Nitrogen Oxides; Non-alcoholic Fatty Liver Disease; Nucleosides; Nucleotidyltransferases; Nutritional Status; Obesity, Morbid; Ofloxacin; Oils, Volatile; Oligopeptides; Oncogene Protein v-akt; Optical Imaging; Organic Cation Transport Proteins; Organophosphonates; Osteoarthritis; Osteoarthritis, Hip; Osteoarthritis, Knee; Osteoblasts; Osteogenesis; Oxidation-Reduction; Oxidative Stress; Oxides; Oxygen Isotopes; Pancreas; Pancreaticoduodenectomy; Pandemics; Particle Size; Particulate Matter; Patient Acceptance of Health Care; Patient Compliance; PC-3 Cells; Peptide Fragments; Peptides; Periodontal Attachment Loss; Periodontal Index; Periodontal Pocket; Periodontitis; Peroxides; Peru; Pest Control, Biological; Phosphatidylinositol 3-Kinase; Phosphatidylinositol 3-Kinases; Phylogeny; Pilot Projects; Piperidines; Plant Bark; Plant Extracts; Plant Leaves; Plasmids; Platelet Function Tests; Pneumonia, Viral; Podocytes; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Polyethylene Terephthalates; Polymers; Polymorphism, Single Nucleotide; Porosity; Portugal; Positron-Emission Tomography; Postoperative Complications; Postural Balance; Potassium Channels, Inwardly Rectifying; Povidone; Powders; Precancerous Conditions; Precision Medicine; Predictive Value of Tests; Pregnancy; Prenatal Care; Prognosis; Promoter Regions, Genetic; Prospective Studies; Prostatectomy; Prostatic Neoplasms; Proteasome Inhibitors; Protective Agents; Protein Binding; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Protein Transport; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins c-akt; Psychiatric Nursing; PTEN Phosphohydrolase; Pulmonary Embolism; Pyrimethamine; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Rats, Wistar; Reactive Oxygen Species; Receptor, ErbB-2; Receptor, IGF Type 1; Receptors, Estrogen; Receptors, G-Protein-Coupled; Recombinational DNA Repair; Recovery of Function; Regional Blood Flow; Renal Dialysis; Renin; Renin-Angiotensin System; Reperfusion Injury; Reproducibility of Results; Republic of Korea; Respiratory Distress Syndrome; Retrospective Studies; Rhodamines; Risk Assessment; Risk Factors; RNA, Long Noncoding; RNA, Messenger; Running; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Salinity; Salmeterol Xinafoate; Sarcoma; Seasons; Shoulder Injuries; Signal Transduction; Silicon Dioxide; Silver; Sirtuin 1; Sirtuins; Skull Fractures; Social Determinants of Health; Sodium; Sodium Fluoride; Sodium Potassium Chloride Symporter Inhibitors; Sodium-Glucose Transporter 2 Inhibitors; Soil; Soil Pollutants; Spain; Spectrophotometry; Spectroscopy, Fourier Transform Infrared; Staphylococcal Protein A; Staphylococcus aureus; Stem Cells; Stereoisomerism; Stomach Neoplasms; Streptomyces; Strontium; Structure-Activity Relationship; Students, Nursing; Substance-Related Disorders; Succinic Acid; Sulfur; Surface Properties; Survival Rate; Survivin; Symporters; T-Lymphocytes; Temozolomide; Tensile Strength; Thiazoles; Thiobacillus; Thiohydantoins; Thiourea; Thrombectomy; Time Factors; Titanium; Tobacco Mosaic Virus; Tobacco Use Disorder; Toll-Like Receptor 4; Toluene; Tomography, X-Ray Computed; TOR Serine-Threonine Kinases; Toxicity Tests, Acute; Toxicity Tests, Subacute; Transcriptional Activation; Treatment Outcome; Troponin I; Tumor Cells, Cultured; Tumor Escape; Tumor Hypoxia; Tumor Microenvironment; Tumor Necrosis Factor Inhibitors; Tumor Necrosis Factor-alpha; Tyrosine; Ubiquitin-Protein Ligases; Ubiquitination; Ultrasonic Waves; United Kingdom; United States; United States Department of Veterans Affairs; Up-Regulation; Urea; Uric Acid; Urinary Bladder Neoplasms; Urinary Bladder, Neurogenic; Urine; Urodynamics; User-Computer Interface; Vemurafenib; Verbenaceae; Veterans; Veterans Health; Viral Load; Virtual Reality; Vitiligo; Water Pollutants, Chemical; Wildfires; Wnt Signaling Pathway; Wound Healing; X-Ray Diffraction; Xenograft Model Antitumor Assays; Xylenes; Young Adult; Zinc; Zinc Oxide; Zinc Sulfate; Zoonoses | 2021 |
Sitagliptin/metformin improves the fertilization rate and embryo quality in polycystic ovary syndrome patients through increasing the expression of GDF9 and BMP15: A new alternative to metformin (a randomized trial).
Topics: Bone Morphogenetic Protein 15; Female; Fertilization; Growth Differentiation Factor 9; Humans; Leptin; Metformin; Polycystic Ovary Syndrome; RNA, Messenger; Sitagliptin Phosphate | 2022 |
Metformin versus insulin for gestational diabetes: Adiposity variables and adipocytokines in offspring at age of 9 years.
Topics: Adipokines; Adiponectin; Adiposity; Child; Diabetes, Gestational; Female; Humans; Inflammation; Insulin; Insulin, Regular, Human; Leptin; Male; Metformin; Obesity; Pregnancy | 2023 |
72 other study(ies) available for metformin and leptin
| Article | Year |
|---|---|
Conference report: renal disease, metformin, and the adipocyte.
Topics: Adipocytes; Animals; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Glycation End Products, Advanced; Glycosylation; Humans; Hypoglycemic Agents; Kidney Failure, Chronic; Leptin; Metformin; Mice; Mice, Mutant Strains; Mice, Obese; Obesity; Protein Biosynthesis; Proteins | 1996 |
Differential regulation of uncoupling proteins by chronic treatments with beta 3-adrenergic agonist BRL 35135 and metformin in obese fa/fa Zucker rats.
Topics: Adipose Tissue; Adrenergic beta-Agonists; Analysis of Variance; Animals; Carrier Proteins; Eating; Endocrine Glands; Energy Metabolism; Gene Expression Regulation; Hypoglycemic Agents; Insulin; Ion Channels; Leptin; Male; Membrane Proteins; Membrane Transport Proteins; Metformin; Mitochondrial Proteins; Muscle, Skeletal; Obesity; Phenethylamines; Protein Biosynthesis; Proteins; Rats; Rats, Zucker; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-3; Uncoupling Agents; Uncoupling Protein 1; Uncoupling Protein 2; Uncoupling Protein 3; Weight Gain | 1998 |
Inhibition of leptin secretion by insulin and metformin in cultured rat adipose tissue.
Topics: Adipose Tissue; Animals; Cells, Cultured; Culture Media; Culture Techniques; Dexamethasone; Glyburide; Hydrocortisone; Hypoglycemic Agents; Insulin; Leptin; Metformin; Rats; Rats, Sprague-Dawley | 2000 |
Effects of metformin and vanadium on leptin secretion from cultured rat adipocytes.
Topics: Adipocytes; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Glucose; Hypoglycemic Agents; Insulin; Lactic Acid; Leptin; Male; Metformin; Rats; Rats, Sprague-Dawley; Regression Analysis; Time Factors; Vanadium | 2000 |
Comparison of the metabolic effects of metformin and troglitazone on fructose-induced insulin resistance in male Sprague-Dawley rats.
Topics: Animals; Chromans; Fatty Acids, Nonesterified; Fructose; Hypoglycemic Agents; Insulin Resistance; Leptin; Male; Metformin; Rats; Rats, Sprague-Dawley; Thiazoles; Thiazolidinediones; Troglitazone | 2001 |
Metformin reduces weight, centripetal obesity, insulin, leptin, and low-density lipoprotein cholesterol in nondiabetic, morbidly obese subjects with body mass index greater than 30.
Topics: Adult; Aged; Body Mass Index; Body Weight; Cholesterol, LDL; Coronary Disease; Fasting; Female; Humans; Hypoglycemic Agents; Insulin; Leptin; Male; Metformin; Middle Aged; Obesity; Risk Factors; Tissue Plasminogen Activator | 2001 |
Anti-diabetic property of ethanolic extract of Andrographis paniculata in streptozotocin-diabetic rats.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Drugs, Chinese Herbal; Glucose Tolerance Test; Glucose-6-Phosphatase; Hypoglycemic Agents; Leptin; Magnoliopsida; Male; Metformin; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Triglycerides | 2000 |
The effects of metformin and diet on plasma testosterone and leptin levels in obese men.
Topics: Adult; Body Constitution; Body Mass Index; Dehydroepiandrosterone Sulfate; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diet, Reducing; Energy Intake; Female; Follicle Stimulating Hormone; Humans; Hypoglycemic Agents; Leptin; Luteinizing Hormone; Male; Metformin; Middle Aged; Obesity; Sex Hormone-Binding Globulin; Testosterone | 2001 |
Nonalcoholic steatohepatitis: role of leptin in pathogenesis and benefits of metformin in treatment.
Topics: Fatty Liver; Female; Follow-Up Studies; Humans; Leptin; Liver Function Tests; Male; Metformin; Risk Assessment; Severity of Illness Index; Treatment Outcome | 2003 |
[Effects of metformin on gonadotropin-induced ovulation in patients with polycystic ovary syndrome].
Topics: Adult; Female; Follicle Stimulating Hormone; Gonadotropins; Humans; Insulin; Leptin; Metformin; Ovulation; Polycystic Ovary Syndrome; Pregnancy | 2003 |
Metformin, but not leptin, regulates AMP-activated protein kinase in pancreatic islets: impact on glucose-stimulated insulin secretion.
Topics: AMP-Activated Protein Kinases; Animals; Cell Line, Tumor; Enzyme Activation; Gene Expression Regulation, Enzymologic; Glucose; Humans; Hypoglycemic Agents; Insulin; Insulin Secretion; Islets of Langerhans; Leptin; Metformin; Mice; Mice, Inbred Strains; Multienzyme Complexes; Phosphorylation; Protein Serine-Threonine Kinases; Rats; Rats, Wistar | 2004 |
Lipoatrophic diabetes in an elderly woman: clinical course and serum adipocytokine concentrations.
Topics: Adiponectin; Aged; Blood Glucose; Cytokines; Diabetes Mellitus, Lipoatrophic; Diabetes Mellitus, Type 2; Female; Fenofibrate; Hormones, Ectopic; Humans; Insulin; Intercellular Signaling Peptides and Proteins; Leptin; Metformin; Resistin; Tumor Necrosis Factor-alpha; Weight Loss | 2004 |
[Current concept of polycystic ovary syndrome].
Topics: Body Mass Index; Female; Humans; Insulin Resistance; Leptin; Metformin; Obesity; Polycystic Ovary Syndrome; Progestins; Risk Factors | 2004 |
Metformin inhibits leptin secretion via a mitogen-activated protein kinase signalling pathway in brown adipocytes.
Topics: Adipocytes; Adipose Tissue, Brown; Animals; Blotting, Western; Cell Line; Dose-Response Relationship, Drug; Hypoglycemic Agents; Leptin; Metformin; Mice; Mitogen-Activated Protein Kinase 1; Stimulation, Chemical | 2004 |
The effect of short-term glycemic regulation with gliclazide and metformin on postprandial lipemia.
Topics: Blood Glucose; Diabetes Mellitus, Type 2; Fasting; Gliclazide; Homeostasis; Humans; Hypoglycemic Agents; Leptin; Metformin; Postprandial Period | 2005 |
Signaling pathways involved in human vascular smooth muscle cell proliferation and matrix metalloproteinase-2 expression induced by leptin: inhibitory effect of metformin.
Topics: Aorta; Cell Division; Cells, Cultured; Enzyme Activation; Humans; Leptin; Matrix Metalloproteinase 2; Metformin; Muscle, Smooth, Vascular; NADPH Oxidases; Protein Kinase C | 2005 |
Increased plasma adiponectin in response to pioglitazone does not result from increased gene expression.
Topics: Abdominal Fat; Adiponectin; Adult; Blood Glucose; Female; Gene Expression; Glucose Intolerance; Glucose Tolerance Test; Humans; Hypoglycemic Agents; Insulin; Leptin; Metformin; Middle Aged; Pioglitazone; Resistin; Thiazolidinediones | 2006 |
Metformin restores leptin sensitivity in high-fat-fed obese rats with leptin resistance.
Topics: Adipose Tissue; AMP-Activated Protein Kinases; Animals; Corticotropin-Releasing Hormone; Dietary Fats; Hypoglycemic Agents; Hypothalamus; Insulin; Leptin; Male; Metformin; Multienzyme Complexes; Obesity; Pro-Opiomelanocortin; Protein Serine-Threonine Kinases; Rats; Rats, Sprague-Dawley; Signal Transduction; STAT3 Transcription Factor | 2006 |
Obesity is associated with altered metabolic and reproductive activity in the mare: effects of metformin on insulin sensitivity and reproductive cyclicity.
Topics: Animals; Breeding; Dose-Response Relationship, Drug; Estrous Cycle; Female; Food Deprivation; Horse Diseases; Horses; Hypoglycemic Agents; Insulin; Insulin Resistance; Leptin; Metformin; Obesity; Reproduction; Seasons; Thyroxine | 2006 |
The ratio of leptin to adiponectin can be used as an index of insulin resistance.
Topics: Adiponectin; Blood Glucose; Body Mass Index; Diabetes Mellitus, Type 2; Female; Glucose Clamp Technique; Glucose Tolerance Test; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin Resistance; Leptin; Male; Metformin; Middle Aged; Pioglitazone; Thiazolidinediones | 2008 |
Metformin normalizes endothelial function by suppressing vasoconstrictor prostanoids in mesenteric arteries from OLETF rats, a model of type 2 diabetes.
Topics: Animals; Blood Glucose; Blood Pressure; Cholesterol; Cyclooxygenase 1; Cyclooxygenase 2; Diabetes Mellitus, Type 2; Endothelium, Vascular; Fatty Acids, Nonesterified; Hypoglycemic Agents; Insulin; Isometric Contraction; Leptin; Mesenteric Arteries; Metformin; Muscle, Smooth, Vascular; Nitric Oxide; Prostaglandins; Rats; Rats, Inbred OLETF; Superoxides; Triglycerides; Vasoconstrictor Agents | 2008 |
[Avandia and avandamet in the treatment of patients with diabetes mellitus type 2: effects on secretion of some fat tissue hormones].
Topics: Adiponectin; Adipose Tissue; Diabetes Mellitus, Type 2; Drug Combinations; Female; Fibrinolytic Agents; Ghrelin; Humans; Hypoglycemic Agents; Insulin; Leptin; Male; Metformin; Middle Aged; Resistin; Rosiglitazone; Thiazoles; Thiazolidinediones | 2008 |
Antihyperglycaemic medication modifies factors of postprandial satiety in type 2 diabetes.
Topics: Aged; Amino Acids; Area Under Curve; Blood Glucose; Cross-Over Studies; Diabetes Mellitus, Type 2; Dipeptides; Fasting; Gastric Emptying; Glucagon-Like Peptide 1; Glyburide; Humans; Hunger; Hypoglycemic Agents; Insulin; Leptin; Male; Metformin; Middle Aged; Postprandial Period; Satiation; Thiazolidinediones | 2009 |
Bone disease, gestational diabetes mellitus, and health care.
Topics: Bone Density; Bone Diseases; Collagen; Diabetes Mellitus, Type 2; Diabetes, Gestational; Female; Fractures, Bone; Homeostasis; Humans; Hypoglycemic Agents; Leptin; Metformin; Osteoporosis; Pregnancy; Thiazolidinediones | 2009 |
Baicalin reduces mitochondrial damage in streptozotocin-induced diabetic Wistar rats.
Topics: Animals; Citrate (si)-Synthase; Diabetes Complications; Diabetes Mellitus, Experimental; Flavonoids; Free Radical Scavengers; Hepatocytes; Hyperglycemia; Hypoglycemic Agents; Insulin-Secreting Cells; Leptin; Liver; Male; Metformin; Microscopy, Electron, Transmission; Mitochondria; Mitochondria, Liver; Mitochondrial Membranes; Oxidative Stress; Rats; Rats, Wistar | 2009 |
Serum galectin-3 is elevated in obesity and negatively correlates with glycosylated hemoglobin in type 2 diabetes.
Topics: Adipocytes; Adult; Aged; Animals; Blotting, Western; Body Mass Index; Cells, Cultured; Diabetes Mellitus, Type 2; Enzyme-Linked Immunosorbent Assay; Female; Galectin 3; Glycated Hemoglobin; Humans; Intra-Abdominal Fat; Leptin; Male; Metformin; Mice; Middle Aged; Obesity; Resistin; Statistics, Nonparametric | 2010 |
Effects of metformin on serum levels of sex hormone, leptin and insulin in ovariectomized Sprague-Dawley rats.
Topics: Animals; Body Weight; Estradiol; Female; Gonadal Steroid Hormones; Hypoglycemic Agents; Insulin; Leptin; Metformin; Ovariectomy; Progesterone; Rats; Rats, Sprague-Dawley | 2009 |
Specific roles of the p110alpha isoform of phosphatidylinsositol 3-kinase in hepatic insulin signaling and metabolic regulation.
Topics: Animals; Blood Glucose; Class I Phosphatidylinositol 3-Kinases; Diabetes Mellitus; Down-Regulation; Energy Metabolism; Glucose Intolerance; Insulin; Leptin; Lipids; Liver; Metformin; Mice; Mice, Knockout; Phosphatidylinositol 3-Kinases; Phosphatidylinositol Phosphates; Proto-Oncogene Proteins c-akt; Signal Transduction | 2010 |
The anorexigenic effects of metformin involve increases in hypothalamic leptin receptor expression.
Topics: Agouti-Related Protein; Animals; Blood Glucose; Body Weight; Eating; Humans; Hypoglycemic Agents; Hypothalamus; Insulin; Leptin; Male; Metformin; Neuropeptide Y; Obesity; Pro-Opiomelanocortin; Random Allocation; Rats; Rats, Long-Evans; Receptors, Leptin; Reverse Transcriptase Polymerase Chain Reaction; RNA; Statistics, Nonparametric | 2011 |
Metformin reduces body weight gain and improves glucose intolerance in high-fat diet-fed C57BL/6J mice.
Topics: Animals; Blood Glucose; Body Weight; Dietary Fats; Energy Intake; Glucagon-Like Peptide 1; Glucose Intolerance; Glucose Tolerance Test; Hyperglycemia; Hyperinsulinism; Hypoglycemic Agents; Insulin; Leptin; Male; Metformin; Mice; Mice, Inbred C57BL; Obesity; Pioglitazone; Thiazolidinediones; Weight Gain | 2010 |
Increased expression of hepatic organic cation transporter 1 and hepatic distribution of metformin in high-fat diet-induced obese mice.
Topics: Animals; Dietary Fats; Hep G2 Cells; Humans; Hypoglycemic Agents; Insulin; Leptin; Liver; Male; Metformin; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; Octamer Transcription Factor-1; RNA, Messenger; Tumor Necrosis Factor-alpha | 2010 |
Pro12Ala polymorphism of the PPAR-γ2 gene, metabolic syndrome and response to metformin in clozapine-treated patients.
Topics: Adult; Aged; Alanine; Antipsychotic Agents; Blood Glucose; Clozapine; Enzyme-Linked Immunosorbent Assay; Female; Gene Frequency; Genotype; Humans; Hypoglycemic Agents; Insulin; Leptin; Male; Metabolic Diseases; Metformin; Middle Aged; Polymorphism, Genetic; PPAR gamma; Proline | 2012 |
Metformin attenuates Alzheimer's disease-like neuropathology in obese, leptin-resistant mice.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Conditioning, Psychological; Diabetes Mellitus, Type 2; Disease Models, Animal; Drug Resistance; Fear; Hippocampus; Hypoglycemic Agents; JNK Mitogen-Activated Protein Kinases; Leptin; Male; Maze Learning; Memory; Metformin; Mice; Mice, Obese; Neurofibrillary Tangles; Phosphorylation; Plaque, Amyloid; Protein Phosphatase 2; Synaptophysin; tau Proteins; Vesicular Transport Proteins | 2012 |
A high-fat-diet-induced cognitive deficit in rats that is not prevented by improving insulin sensitivity with metformin.
Topics: Alzheimer Disease; Animals; Behavior, Animal; Body Weight; Brain; Cognition Disorders; Conditioning, Operant; Dietary Fats; Disease Models, Animal; Hormones; Hypoglycemic Agents; Insulin Resistance; Leptin; Male; Metformin; Nerve Tissue Proteins; Rats; Rats, Wistar; Signal Transduction; Treatment Failure | 2012 |
Metformin affects the circadian clock and metabolic rhythms in a tissue-specific manner.
Topics: Acetyl-CoA Carboxylase; AMP-Activated Protein Kinases; Animals; Basal Metabolism; Circadian Clocks; Glucagon; Leptin; Liver; Metformin; Mice; Motor Activity; Muscle, Skeletal; Organ Specificity; Protein Serine-Threonine Kinases | 2012 |
Effects of endurance exercise training, metformin, and their combination on adipose tissue leptin and IL-10 secretion in OLETF rats.
Topics: Adipose Tissue; Animals; Combined Modality Therapy; Diabetes Mellitus, Type 2; Interleukin-10; Leptin; Male; Metformin; Physical Conditioning, Animal; Physical Endurance; Rats; Rats, Inbred OLETF; Treatment Outcome | 2012 |
High levels of leptin are associated with poor self-rated health in men and women with type 2 diabetes treated with metformin.
Topics: Adult; Aged; Body Mass Index; Diabetes Mellitus, Type 2; Diagnostic Self Evaluation; Female; Humans; Hypoglycemic Agents; Leptin; Male; Metformin; Middle Aged; Randomized Controlled Trials as Topic | 2013 |
[D-Leu-4]-OB3, an orally bioavailable leptin-related synthetic peptide insulin sensitizer: a study comparing the efficacies of [D-Leu-4]-OB3 and metformin on energy balance and glycemic regulation in insulin-deficient male Swiss Webster mice.
Topics: Administration, Oral; Animals; Biological Availability; Blood Glucose; Disease Models, Animal; Energy Metabolism; Hypoglycemic Agents; Insulin; Leptin; Male; Metformin; Mice; Peptide Fragments | 2013 |
Metformin inhibits skin tumor promotion in overweight and obese mice.
Topics: Adenylate Kinase; Adiponectin; Animals; Body Weight; Carcinogenesis; Carcinoma, Squamous Cell; Diet; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Insulin; Insulin-Like Growth Factor I; Leptin; Mechanistic Target of Rapamycin Complex 1; Metformin; Mice; Mice, Obese; Multiprotein Complexes; Neoplasms, Experimental; Obesity; Overweight; Papilloma; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Sirolimus; Skin Neoplasms; Tetradecanoylphorbol Acetate; TOR Serine-Threonine Kinases | 2014 |
Polycystic ovaries and obesity.
Topics: Adipokines; Adiponectin; Female; Humans; Hyperandrogenism; Hyperinsulinism; Hypoglycemic Agents; Infertility, Female; Insulin Resistance; Leptin; Life Style; Luteinizing Hormone; Metformin; Nicotinamide Phosphoribosyltransferase; Obesity; Ovulation Induction; Polycystic Ovary Syndrome; Resistin | 2015 |
The brighter (and evolutionarily older) face of the metabolic syndrome: evidence from Trypanosoma cruzi infection in CD-1 mice.
Topics: Adipose Tissue, White; Adiposity; Animals; Cell Line; Chagas Disease; Cytokines; Energy Metabolism; Foreskin; Heart Ventricles; Humans; Hypoglycemic Agents; Leptin; Male; Metabolic Syndrome; Metformin; Mice, Inbred Strains; Models, Immunological; Obesity; Random Allocation; Survival Analysis; Trypanosoma cruzi | 2015 |
[Association between levels of serum leptin and insulin resistance in patients with polycystic ovary syndrome].
Topics: Body Mass Index; Female; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Leptin; Metformin; Obesity; Polycystic Ovary Syndrome; Pregnancy | 2014 |
Immunologic Effects of Metformin and Pioglitazone Treatment on Metabolic Syndrome and Multiple Sclerosis.
Topics: Adipokines; Anti-Inflammatory Agents; Brain; Cohort Studies; Cytokines; Disability Evaluation; Dose-Response Relationship, Drug; Female; Gene Expression Regulation; Humans; Image Processing, Computer-Assisted; Leptin; Magnetic Resonance Imaging; Male; Metformin; Multiple Sclerosis; Obesity; Pioglitazone; PPAR gamma; RNA, Messenger; Statistics, Nonparametric; T-Lymphocytes, Regulatory; Thiazolidinediones; Time Factors | 2016 |
The roles of tricellular tight junction protein lipolysis-stimulated lipoprotein receptor in malignancy of human endometrial cancer cells.
Topics: Adiponectin; Berberine; Cell Line, Tumor; Cell Movement; Cell Proliferation; Down-Regulation; Endometrial Neoplasms; Endometrium; Epithelial Cells; Female; Gene Knockdown Techniques; Humans; Hypoglycemic Agents; Leptin; MARVEL Domain Containing 2 Protein; Metformin; Neoplasm Invasiveness; Receptors, Lipoprotein; Risk Factors; RNA Interference; RNA, Small Interfering; Tight Junctions; Transcription Factors | 2016 |
Type 2 diabetes and metabolic syndrome - adipokine levels and effect of drugs.
Topics: Adiponectin; Adult; Diabetes Mellitus, Type 2; Female; Humans; Hypoglycemic Agents; Leptin; Male; Metabolic Syndrome; Metformin; Middle Aged; Resistin; Sulfonylurea Compounds | 2017 |
Prospective evaluation of the molecular effects of metformin on the endometrium in women with newly diagnosed endometrial cancer: A window of opportunity study.
Topics: Adult; Aged; AMP-Activated Protein Kinases; Apoptosis; Biomarkers, Tumor; Carcinoma, Endometrioid; Caspase 3; Cell Proliferation; Cytokines; Endometrial Neoplasms; Endometrium; Female; GPI-Linked Proteins; Humans; Hypoglycemic Agents; Immunohistochemistry; Insulin; Insulin-Like Growth Factor I; Ki-67 Antigen; Lectins; Leptin; Metformin; Middle Aged; Mitogen-Activated Protein Kinase 3; Phosphatidylinositol 3-Kinases; Phosphoproteins; Prospective Studies; Proto-Oncogene Proteins c-akt | 2016 |
The effect of sitagliptin on obese patients with insulin treatment-induced diabetes mellitus.
Topics: Adiponectin; Adult; Aged; Blood Glucose; Body Mass Index; Diabetes Mellitus, Type 2; Fasting; Female; Glycated Hemoglobin; Humans; Hypoglycemia; Insulin; Insulin Resistance; Leptin; Male; Metformin; Middle Aged; Nicotinamide Phosphoribosyltransferase; Obesity; Sitagliptin Phosphate; Triglycerides | 2017 |
IGF-1R and Leptin Expression Profile and the Effects of Metformin Treatment on Metabolic and Endocrine Parameters in PCOS Mice.
Topics: Animals; Blood Glucose; Body Weight; Female; Gene Expression Regulation; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Leptin; Metformin; Mice; Mice, Obese; Polycystic Ovary Syndrome; Receptor, IGF Type 1; Receptors, Leptin | 2017 |
The evidence of metabolic-improving effect of metformin in Ay/a mice with genetically-induced melanocortin obesity and the contribution of hypothalamic mechanisms to this effect.
Topics: Agouti-Related Protein; Animals; Body Weight; Female; Gene Expression Regulation; Hypoglycemic Agents; Hypothalamus; Leptin; Melanocortins; Metformin; Mice; Mice, Inbred C57BL; Mice, Obese; Neuropeptide Y; Obesity; Receptors, Leptin | 2019 |
Pericoronary fat inflammation and Major Adverse Cardiac Events (MACE) in prediabetic patients with acute myocardial infarction: effects of metformin.
Topics: Adiponectin; Adipose Tissue; Aged; Biomarkers; Coronary Artery Bypass; Female; Humans; Hypoglycemic Agents; Inflammation Mediators; Italy; Leptin; Male; Metformin; Middle Aged; Myocardial Infarction; Prediabetic State; Prospective Studies; Risk Factors; Sirtuins; Time Factors; Treatment Outcome; Tumor Necrosis Factor-alpha | 2019 |
Berberine attenuated olanzapine-induced metabolic alterations in mice: Targeting transient receptor potential vanilloid type 1 and 3 channels.
Topics: Animals; Antipsychotic Agents; Berberine; Body Temperature; Body Weight; Cytokines; Drinking; Female; Gene Expression Regulation; Ghrelin; Hypothalamus; Leptin; Metabolic Diseases; Metformin; Mice; Mice, Inbred BALB C; Molecular Targeted Therapy; Neuropeptides; Obesity; Olanzapine; RNA, Messenger; Signal Transduction; Treatment Outcome; TRPV Cation Channels | 2020 |
Effect of metformin on testicular expression and localization of leptin receptor and levels of leptin in the diabetic mice.
Topics: Animals; Cell Proliferation; Diabetes Mellitus, Experimental; Gene Expression; Leptin; Leydig Cells; Male; Metformin; Mice; Receptors, Leptin; Streptozocin; Testis; Testosterone; Tissue Distribution | 2020 |
Stress-induced intestinal barrier dysfunction is exacerbated during diet-induced obesity.
Topics: Animals; Cecum; Colon; Corticosterone; Diet, High-Fat; Gastrointestinal Microbiome; Humans; Hypoglycemic Agents; Intestinal Mucosa; Irritable Bowel Syndrome; Leptin; Male; Metformin; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; Permeability; Prevalence; Stress, Physiological | 2020 |
Metformin alleviates hyperuricaemia-induced serum FFA elevation and insulin resistance by inhibiting adipocyte hypertrophy and reversing suppressed white adipose tissue beiging.
Topics: 3T3-L1 Cells; Adenylate Kinase; Adipocytes; Adipose Tissue, Beige; Adipose Tissue, White; Adult; Animals; Enzyme Activation; Fatty Acids, Nonesterified; Female; Humans; Hypertrophy; Hyperuricemia; Insulin Resistance; Leptin; Lipogenesis; Lipolysis; Male; Metformin; Mice; Mice, Inbred C57BL; Middle Aged; Signal Transduction; Triglycerides; Uric Acid | 2020 |
Normalization of Testicular Steroidogenesis and Spermatogenesis in Male Rats with Type 2 Diabetes Mellitus under the Conditions of Metformin Therapy.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet, High-Fat; Hypoglycemic Agents; Leptin; Male; Metformin; Progesterone; Rats, Wistar; Receptors, Leptin; Spermatogenesis; Spermatozoa; Steroids; Testis | 2020 |
Histological, immunohistochemical and biochemical effects of bee bread on stomach tissue of obese rats.
Topics: Animals; Female; Ghrelin; Hypoglycemic Agents; Leptin; Metformin; Necrosis; Obesity; Propolis; Rats; Rats, Sprague-Dawley; Stomach | 2020 |
Early metformin treatment improves pancreatic function and prevents metabolic dysfunction in early overfeeding male rats at adulthood.
Topics: Adipose Tissue, White; Animals; Animals, Newborn; Blood Glucose; Body Composition; Body Weight; Female; Insulin; Insulin Resistance; Islets of Langerhans; Leptin; Male; Metabolic Diseases; Metformin; Obesity; Overnutrition; Rats; Rats, Wistar; Weight Gain | 2020 |
Metabolic benefits of novel histamine H
Topics: Adipose Tissue; Animals; Body Weight; C-Peptide; Carrier Proteins; Cholesterol; Energy Intake; Feeding Behavior; Female; Glucose Tolerance Test; Histamine Agonists; Histamine Antagonists; Injections, Intraperitoneal; Insulin; Insulin Resistance; Leptin; Ligands; Metformin; Models, Animal; Obesity; Rats, Wistar; Receptors, Histamine H3; Triglycerides | 2021 |
Gestational weight gain, appetite regulating hormones, and metformin treatment in polycystic ovary syndrome: A longitudinal, placebo-controlled study.
Topics: Appetite; Body Mass Index; Cohort Studies; Female; Gestational Weight Gain; Ghrelin; Humans; Leptin; Metformin; Polycystic Ovary Syndrome; Pregnancy; Pregnanolone; Prospective Studies; Randomized Controlled Trials as Topic | 2022 |
The Effects of Separate and Combined Treatment of Male Rats with Type 2 Diabetes with Metformin and Orthosteric and Allosteric Agonists of Luteinizing Hormone Receptor on Steroidogenesis and Spermatogenesis.
Topics: Adenylate Kinase; Allosteric Regulation; Animals; Area Under Curve; Blood Glucose; Body Weight; Diabetes Mellitus, Type 2; Disease Models, Animal; Drug Therapy, Combination; Estradiol; Gene Expression Regulation; Glycated Hemoglobin; Insulin; Insulin Resistance; Leptin; Male; Metformin; Phosphorylation; Rats, Wistar; Receptors, LH; Seminiferous Tubules; Spermatogenesis; Steroids; Testosterone | 2021 |
Development of a Magnetic Nanostructure for Co-delivery of Metformin and Silibinin on Growth of Lung Cancer Cells: Possible Action Through Leptin Gene and its Receptor Regulation.
Topics: A549 Cells; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Gene Expression Regulation, Neoplastic; Humans; Leptin; Lung Neoplasms; Magnetic Phenomena; Metformin; Nanoparticle Drug Delivery System; Polyethylene Glycols; Polylactic Acid-Polyglycolic Acid Copolymer; Receptors, Leptin; Silybin | 2022 |
Metformin ameliorates olanzapine-induced disturbances in POMC neuron number, axonal projection, and hypothalamic leptin resistance.
Topics: Animals; Antipsychotic Agents; Aripiprazole; Female; Hypothalamus; Leptin; Metformin; Mice; Neurons; Obesity; Olanzapine; Pro-Opiomelanocortin | 2022 |
Linagliptin in Combination With Metformin Ameliorates Diabetic Osteoporosis Through Modulating BMP-2 and Sclerostin in the High-Fat Diet Fed C57BL/6 Mice.
Topics: Animals; Biomarkers; Body Weight; Calcium; Cytokines; Diabetes Mellitus, Experimental; Diet, High-Fat; Glucose; Insulin; Leptin; Linagliptin; Metformin; Mice; Mice, Inbred C57BL; Osteocalcin; Osteoporosis | 2022 |
Metformin attenuates osteoarthritis by targeting chondrocytes, synovial macrophages and adipocytes.
Topics: Adipocytes; Animals; Chondrocytes; Diet, High-Fat; Leptin; Macrophages; Metformin; Mice; Mice, Inbred C57BL; Mice, Obese; Osteoarthritis | 2023 |
Circulating THBS1: A Risk Factor for Nonalcoholic Fatty Liver Disease in Obese Children.
Topics: Animals; Child; Cross-Sectional Studies; Humans; Leptin; Liver; Metformin; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Pediatric Obesity; Risk Factors; Thrombospondin 1 | 2023 |
Effect of metformin as an adjuvant therapy to letrozole on estradiol and other biomarkers involved in the pathogenesis of breast cancer in overweight and obese postmenopausal women: a pilot study.
Topics: Biomarkers; Blood Glucose; Breast Neoplasms; Estradiol; Female; Humans; Insulin; Leptin; Letrozole; Metformin; Obesity; Osteocalcin; Overweight; Pilot Projects; Postmenopause; Retrospective Studies | 2023 |
Metformin induces pyroptosis in leptin receptor-defective hepatocytes via overactivation of the AMPK axis.
Topics: AMP-Activated Protein Kinases; Animals; Glucose; Hepatocytes; Leptin; Liver; Metformin; Non-alcoholic Fatty Liver Disease; Pyroptosis; Rats; Rats, Zucker; Receptors, Leptin | 2023 |
Free leptin index, excessive weight gain, and metformin treatment during pregnancy in polycystic ovary syndrome: What about inflammation?
Topics: Female; Humans; Hypoglycemic Agents; Leptin; Metformin; Polycystic Ovary Syndrome; Pregnancy; Weight Gain | 2023 |
Analysis of Antidiabetic Activity of Squalene via In Silico and In Vivo Assay.
Topics: Animals; Antioxidants; Blood Glucose; Diabetes Mellitus, Type 2; Hypoglycemic Agents; Leptin; Metformin; Plant Extracts; Rats; Squalene; Superoxide Dismutase | 2023 |
Leptin and the rs2167270 Polymorphism Are Associated with Glycemic Control in Type Two Diabetes Mellitus Patients on Metformin Therapy.
Topics: Case-Control Studies; Diabetes Mellitus, Type 2; Genetic Predisposition to Disease; Genotype; Glycemic Control; Humans; Leptin; Metformin; Polymorphism, Single Nucleotide | 2023 |
Baseline leptin predicts response to metformin in adolescents with type 1 diabetes and increased body mass index.
Topics: Adolescent; Body Mass Index; Diabetes Mellitus, Type 1; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Leptin; Metformin | 2023 |
[Effect of metformin combined with DPP-4 inhibitor on alveolar bone density in patients with type 2 diabetes mellitus and chronic periodontitis].
Topics: Adiponectin; Bone Density; C-Reactive Protein; Chronic Periodontitis; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Humans; Interleukin-6; Leptin; Metformin; Tumor Necrosis Factor-alpha | 2023 |