metformin has been researched along with interleukin-8 in 20 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (15.00) | 29.6817 |
| 2010's | 11 (55.00) | 24.3611 |
| 2020's | 6 (30.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bruun, JM; Lihn, AS; Pedersen, SB; Richelsen, B | 1 |
| Gerdes, N; Isoda, K; Libby, P; MacFarlane, LA; Schönbeck, U; Tsuboi, N; Young, JL; Zirlik, A | 1 |
| Harada, M; Hasegawa, A; Hirata, T; Hirota, Y; Koga, K; Morimoto, C; Nose, E; Osuga, Y; Tajima, T; Takemura, Y; Taketani, Y; Yano, T; Yoshino, O | 1 |
| Capp, E; Germeyer, A; Jauckus, J; Strowitzki, T; Toth, B; Zorn, M | 1 |
| Ato, M; Bancroft, GJ; Kewcharoenwong, C; Lertmemongkolchai, G; Rinchai, D; Suwannasaen, D; Utispan, K | 1 |
| Andersson, R; Karnevi, E; Rosendahl, AH | 1 |
| Kim, IK; Kim, JM; Kim, JS; Ko, SH; Koh, SJ | 1 |
| Chiovato, L; Coperchini, F; Magri, F; Pignatti, P; Rotondi, M | 1 |
| Agliarulo, I; Amoroso, MR; Arzeni, D; Avolio, R; Esposito, F; Faicchia, D; Gabra, H; Landriscina, M; Lu, H; Maddalena, F; Marone, G; Matarese, G; Matassa, DS; Mazzoccoli, C; Procaccini, C; Recchi, C; Simeon, V; Stronach, E; Zanini, E | 1 |
| Bonten, MM; Cremer, OL; Hoogendijk, AJ; Horn, J; Klein Klouwenberg, PM; Nürnberg, P; Schultz, MJ; Scicluna, BP; van der Poll, T; van Vught, LA; Wiewel, MA | 1 |
| Atkin, SL; Coady, AM; Javed, Z; Kilpatrick, ES; Sathyapalan, T | 1 |
| Do Jung, Y; Li, S; Lian, S; Nguyen, TT; Park, SY; Ung, TT; Xia, Y | 1 |
| Ali, A; Ali, DE; Badshah, H; Ehtesham, E; Malik, MO; Rehman, F; Shah, M; Vitale, SG | 1 |
| Ahn, JM; Bae, WJ; Byeon, HE; Kim, S; Lee, D | 1 |
| Chevet, E; Eldering, E; Favaro, F; Iurlaro, R; Lucendo, E; Majem, B; Marchetti, S; Muñoz-Pinedo, C; Nadal, E; Püschel, F; Redondo-Pedraza, J; Ricci, JE | 1 |
| An, G; Jing, X; Lei, J; Li, W; Luo, M; Meng, D; Ning, Q; Shao, S; Zhang, L; Zhao, L; Zhao, X | 1 |
| Corsini, E; Galbiati, V; Iulini, M; Maddalon, A; Marinovich, M | 1 |
| Ferraresi, A; Isidoro, C; Jamjuntra, P; Therasakvichya, S; Thongchot, S; Thuwajit, C; Thuwajit, P; Warnnissorn, M | 1 |
| Coskun, G; Efendic, F; Erdem, E; Hayretdag, C; Irkorucu, O; Keles, P; Kuras, S; Pence, HH; Polat, S; Saker, D; Sapmaz, E; Sapmaz, T; Sevgin, K; Tekayev, M; Topkaraoglu, S | 1 |
| Aljamili, A; AlKattan, R; Allam, E; Almarshad, H; Almuhanna, N; Alshehri, FA; Alshibani, N; Shalabi, MM | 1 |
3 trial(s) available for metformin and interleukin-8
| Article | Year |
|---|---|
Tumour-educated macrophages display a mixed polarisation and enhance pancreatic cancer cell invasion.
Topics: CD11c Antigen; Cell Line, Tumor; Coculture Techniques; Diabetes Mellitus, Type 2; Female; Glucose; Humans; Hyperglycemia; Hypoglycemic Agents; Interleukin-6; Interleukin-8; Lectins, C-Type; Macrophages; Male; Mannose Receptor; Mannose-Binding Lectins; Metformin; Neoplasm Invasiveness; Pancreatic Neoplasms; Receptors, Cell Surface | 2014 |
Endocannabinoid receptor blockade increases vascular endothelial growth factor and inflammatory markers in obese women with polycystic ovary syndrome.
Topics: Biomarkers; Cannabinoid Receptor Antagonists; Cytokines; Female; Humans; Hyperandrogenism; Inflammation; Interleukin-8; Metformin; Obesity; Piperidines; Polycystic Ovary Syndrome; Pyrazoles; Rimonabant; Vascular Endothelial Growth Factor A; Weight Loss | 2017 |
Treatment with Metformin and Combination of Metformin Plus Pioglitazone on Serum Levels of IL-6 and IL-8 in Polycystic Ovary Syndrome: A Randomized Clinical Trial.
Topics: Adult; Biomarkers; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hypoglycemic Agents; Interleukin-6; Interleukin-8; Metformin; Pioglitazone; Polycystic Ovary Syndrome; Prognosis; Young Adult | 2019 |
17 other study(ies) available for metformin and interleukin-8
| Article | Year |
|---|---|
Monocyte chemoattractant protein-1 release is higher in visceral than subcutaneous human adipose tissue (AT): implication of macrophages resident in the AT.
Topics: Adipocytes; Adipose Tissue; Chemokine CCL2; Chromans; Humans; Interleukin-1; Interleukin-8; Macrophages; Metformin; Skin; Thiazolidinediones; Troglitazone; Tumor Necrosis Factor-alpha; Viscera | 2005 |
Metformin inhibits proinflammatory responses and nuclear factor-kappaB in human vascular wall cells.
Topics: Anti-Inflammatory Agents; Atherosclerosis; Cell Survival; Cells, Cultured; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Endothelium, Vascular; Glucose; Humans; Hypoglycemic Agents; Interleukin-1; Interleukin-6; Interleukin-8; Macrophages; Metformin; Muscle, Smooth, Vascular; NF-kappa B; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Saphenous Vein | 2006 |
Metformin suppresses interleukin (IL)-1beta-induced IL-8 production, aromatase activation, and proliferation of endometriotic stromal cells.
Topics: Adult; Antimetabolites; Aromatase; Biomarkers; Bromodeoxyuridine; Cell Separation; Cell Survival; Cells, Cultured; Endometriosis; Endometrium; Enzyme Activation; Estrogens; Female; Humans; Hypoglycemic Agents; Inflammation; Interleukin-1beta; Interleukin-8; L-Lactate Dehydrogenase; Metformin; Middle Aged; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stromal Cells | 2007 |
Metformin modulates IL-8, IL-1β, ICAM and IGFBP-1 expression in human endometrial stromal cells.
Topics: Endometrium; Enzyme-Linked Immunosorbent Assay; Female; Gene Expression Regulation; Gonadal Steroid Hormones; Humans; In Vitro Techniques; Insulin; Insulin-Like Growth Factor Binding Protein 1; Intercellular Adhesion Molecule-1; Interleukin-1beta; Interleukin-8; Metformin; Prolactin; Stromal Cells | 2011 |
Glibenclamide reduces pro-inflammatory cytokine production by neutrophils of diabetes patients in response to bacterial infection.
Topics: Burkholderia pseudomallei; Diabetes Mellitus, Type 2; Disease Susceptibility; Glyburide; Humans; Hypoglycemic Agents; Interleukin-1beta; Interleukin-8; Melioidosis; Metformin; Neutrophils; Thailand | 2013 |
Anti-inflammatory mechanism of metformin and its effects in intestinal inflammation and colitis-associated colon cancer.
Topics: AMP-Activated Protein Kinases; Animals; Cell Line, Tumor; Colitis; Colonic Neoplasms; Dextran Sulfate; Disease Models, Animal; Humans; Hypoglycemic Agents; I-kappa B Kinase; Inflammation Mediators; Interleukin-8; Intestinal Mucosa; Male; Metformin; Mice; Mice, Inbred C57BL; Molecular Targeted Therapy; NF-kappa B; Severity of Illness Index; Signal Transduction; Tumor Necrosis Factor-alpha | 2014 |
Metformin reverts the secretion of CXCL8 induced by TNF-α in primary cultures of human thyroid cells: an additional indirect anti-tumor effect of the drug.
Topics: Antineoplastic Agents; Carcinoma; Carcinoma, Papillary; Cell Death; Cell Proliferation; Cells, Cultured; Humans; Interleukin-8; Metformin; Primary Cell Culture; Thyroid Cancer, Papillary; Thyroid Gland; Thyroid Neoplasms; Tumor Necrosis Factor-alpha | 2015 |
Oxidative metabolism drives inflammation-induced platinum resistance in human ovarian cancer.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Cell Survival; Cisplatin; Disease-Free Survival; Drug Resistance, Neoplasm; Female; Glycolysis; HSP90 Heat-Shock Proteins; Humans; Immediate-Early Proteins; Inflammation; Interleukin-6; Interleukin-8; Metformin; Ovarian Neoplasms; Oxidative Phosphorylation; Protein Serine-Threonine Kinases; RNA Interference; RNA, Small Interfering | 2016 |
Association of diabetes and diabetes treatment with the host response in critically ill sepsis patients.
Topics: Aged; Biomarkers; Chemokine CX3CL1; Critical Illness; Diabetes Mellitus; E-Selectin; Female; Humans; Hyperglycemia; Inflammation; Insulin; Intensive Care Units; Intercellular Adhesion Molecule-1; Interferon-gamma; Interleukin-10; Interleukin-1beta; Interleukin-6; Interleukin-8; Male; Metformin; Middle Aged; Prospective Studies; Sepsis; Statistics, Nonparametric; Survival Analysis; Treatment Outcome; Tumor Necrosis Factor-alpha | 2016 |
Metformin inhibits lithocholic acid-induced interleukin 8 upregulation in colorectal cancer cells by suppressing ROS production and NF-kB activity.
Topics: Colorectal Neoplasms; HCT116 Cells; Humans; Interleukin-8; Lithocholic Acid; Metformin; NF-kappa B; Reactive Oxygen Species; Up-Regulation | 2019 |
PTPRD-inactivation-induced CXCL8 promotes angiogenesis and metastasis in gastric cancer and is inhibited by metformin.
Topics: Cell Line, Tumor; Down-Regulation; Gene Silencing; Humans; Hypoglycemic Agents; Interleukin-8; Metformin; Neoplasm Metastasis; Neovascularization, Pathologic; Receptor-Like Protein Tyrosine Phosphatases, Class 2; Signal Transduction; Stomach Neoplasms; Transfection | 2019 |
Starvation and antimetabolic therapy promote cytokine release and recruitment of immune cells.
Topics: Activating Transcription Factor 4; Antimetabolites; Cell Death; Deoxyglucose; Epithelial Cells; Gene Expression Regulation; Glucose; Glutamine; HeLa Cells; Humans; Inflammation; Interleukin-6; Interleukin-8; Macrophages; Metformin; Neoplasms; NF-kappa B; Promoter Regions, Genetic; Starvation; Stress, Physiological | 2020 |
Metformin suppresses HIF-1α expression in cancer-associated fibroblasts to prevent tumor-stromal cross talk in breast cancer.
Topics: Adenylate Kinase; Breast Neoplasms; Cancer-Associated Fibroblasts; Cell Line, Tumor; Chemokine CXCL12; Female; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Interleukin-8; MCF-7 Cells; Metformin; Neoplasm Invasiveness; Prolyl Hydroxylases; Signal Transduction; Transforming Growth Factor beta; Tumor Microenvironment; Up-Regulation | 2020 |
In vitro identification of drugs inducing systemic hypersensitivity reactions known in vivo to be associated with specific HLA genotypes.
Topics: B7-2 Antigen; Carbamazepine; Cell Survival; Clozapine; Dideoxynucleosides; Drug Hypersensitivity; Genotype; HLA Antigens; Humans; Intercellular Adhesion Molecule-1; Interleukin-8; Metformin; THP-1 Cells | 2020 |
Interleukin‑8 released by cancer‑associated fibroblasts attenuates the autophagy and promotes the migration of ovarian cancer cells.
Topics: Autophagy; Cancer-Associated Fibroblasts; Cell Line, Tumor; Cell Movement; Cell Proliferation; Culture Media, Conditioned; Female; Gene Expression Regulation, Neoplastic; Humans; Interleukin-8; Metformin; Microtubule-Associated Proteins; Ovarian Neoplasms; Sirolimus; Tumor Microenvironment; Up-Regulation | 2021 |
Effects of metformin, letrozole and atorvastatin on inflammation and apoptosis in experimental peritoneal and ovarian endometriosis in the rat.
Topics: Animals; Apoptosis; Atorvastatin; bcl-2-Associated X Protein; Endometriosis; Female; Humans; Inflammation; Interleukin-6; Interleukin-8; Ki-67 Antigen; Letrozole; Metformin; Proto-Oncogene Proteins c-bcl-2; Rats; Tumor Necrosis Factor-alpha | 2022 |
Effects of metformin on human gingival fibroblasts: an in vitro study.
Topics: Cells, Cultured; Fibroblasts; Gingiva; Humans; Interleukin-8; Lipopolysaccharides; Matrix Metalloproteinase 1; Matrix Metalloproteinase 2; Matrix Metalloproteinase 8; Metformin; Porphyromonas gingivalis | 2023 |