Compounds > metformin

metformin and insulin degludec

metformin has been researched along with insulin degludec in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's16 (94.12)24.3611
2020's1 (5.88)2.80

Authors

AuthorsStudies
Oberpichler-Schwenk, H1
Damci, T; Donnet, JP; Endahl, L; Franek, E; Leiter, LA; Muñoz-Torres, M; Niskanen, L; Skjøth, TV; Vaag, A; Weng, J1
Brod, M; Niemeyer, M; Ocampo Francisco, AM; Philis-Tsimikas, A; Rothman, J1
Cariou, B; Handelsman, Y; Mathieu, C; Ocampo Francisco, AM; Philis-Tsimikas, A; Rana, A; Rodbard, HW; Zinman, B1
Cariou, B; Handelsman, Y; Mathieu, C; Rana, A; Rodbard, HW; Wolden, ML; Zinman, B1
Blevins, TC; Buse, JB; Bøttcher, SG; Langbakke, IH; Rodbard, HW; Thurman, J; Vilsbøll, T1
Bode, BW; Buse, JB; Gough, SC; Linjawi, S; Reiter, PD; Rodbard, HW; Woo, VC; Zacho, M1
Buse, JB; Gough, SC; Kvist, K; Langbakke, IH; Rodbard, HW; Vilsbøll, T; Woo, V1
Buse, JB; García-Hernández, P; Lehmann, L; Lingvay, I; Norwood, P; Pérez Manghi, F; Tarp-Johansen, MJ1
Gupta, Y; Kalra, S1
Andersen, TH; Aroda, VR; Bailey, TS; Cariou, B; Kumar, S; Leiter, LA; Philis-Tsimikas, A; Raskin, P; Zacho, J1
Gall, MA; Hirao, K; Hyllested-Winge, J; Kaneko, S; Taneda, S1
Gross, JL; Hansen, CT; Lv, X; Pan, C; Sun, L; Wagner, R; Xu, H; Yang, W1
Ihana-Sugiyama, N; Kakei, M; Noda, M; Sugiyama, T; Tsujimoto, T; Yamamoto-Honda, R1
Chandarana, K; Harris, S; Jaeckel, E; Jódar, E; Lingvay, I; Ranthe, MF1
Blasetti, A; Castorani, V; Chiarelli, F; Comegna, L; Giannini, C; Mohn, A; Polidori, N1

Reviews

1 review(s) available for metformin and insulin degludec

ArticleYear
Benefits of combination of insulin degludec and liraglutide are independent of baseline glycated haemoglobin level and duration of type 2 diabetes.
    Diabetes, obesity & metabolism, 2016, Volume: 18, Issue:1

    Topics: Aged; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Glycated Hemoglobin; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin, Long-Acting; Liraglutide; Male; Metformin; Middle Aged; Randomized Controlled Trials as Topic; Time Factors; Treatment Outcome

2016

Trials

12 trial(s) available for metformin and insulin degludec

ArticleYear
Comparison of a soluble co-formulation of insulin degludec/insulin aspart vs biphasic insulin aspart 30 in type 2 diabetes: a randomised trial.
    European journal of endocrinology, 2012, Volume: 167, Issue:2

    Topics: Adolescent; Adult; Aged; Biphasic Insulins; Chemistry, Pharmaceutical; Diabetes Mellitus, Type 2; Drug Administration Schedule; Drug Combinations; Female; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin Aspart; Insulin, Isophane; Insulin, Long-Acting; Male; Metformin; Middle Aged; Solubility; Treatment Outcome; Young Adult

2012
Insulin degludec once-daily in type 2 diabetes: simple or step-wise titration (BEGIN: once simple use).
    Advances in therapy, 2013, Volume: 30, Issue:6

    Topics: Aged; Algorithms; Blood Glucose Self-Monitoring; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Hypoglycemic Agents; Insulin, Long-Acting; Male; Metformin; Middle Aged; Treatment Outcome

2013
A comparison of adding liraglutide versus a single daily dose of insulin aspart to insulin degludec in subjects with type 2 diabetes (BEGIN: VICTOZA ADD-ON).
    Diabetes, obesity & metabolism, 2014, Volume: 16, Issue:7

    Topics: Blood Glucose; Body Mass Index; Diabetes Mellitus, Type 2; Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; Female; Glucagon-Like Peptide 1; Humans; Hypoglycemic Agents; Insulin Aspart; Insulin, Long-Acting; Liraglutide; Male; Metformin; Middle Aged; Treatment Outcome; Weight Loss

2014
Health status and hypoglycaemia with insulin degludec versus insulin glargine: a 2-year trial in insulin-naïve patients with type 2 diabetes.
    Diabetes, obesity & metabolism, 2014, Volume: 16, Issue:9

    Topics: Blood Glucose; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Drug Administration Schedule; Drug Therapy, Combination; Health Status; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin Glargine; Insulin, Long-Acting; Metformin; Treatment Outcome

2014
Contribution of liraglutide in the fixed-ratio combination of insulin degludec and liraglutide (IDegLira).
    Diabetes care, 2014, Volume: 37, Issue:11

    Topics: Aged; Blood Glucose; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Female; Glucagon-Like Peptide 1; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin, Long-Acting; Liraglutide; Male; Metformin; Middle Aged; Sulfonylurea Compounds; Treatment Outcome; Weight Loss

2014
One-year efficacy and safety of a fixed combination of insulin degludec and liraglutide in patients with type 2 diabetes: results of a 26-week extension to a 26-week main trial.
    Diabetes, obesity & metabolism, 2015, Volume: 17, Issue:10

    Topics: Aged; Blood Glucose; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Drug Therapy, Combination; Fasting; Female; Glycated Hemoglobin; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin, Long-Acting; Liraglutide; Male; Metformin; Middle Aged; Pioglitazone; Thiazolidinediones; Weight Loss

2015
Effect of Insulin Glargine Up-titration vs Insulin Degludec/Liraglutide on Glycated Hemoglobin Levels in Patients With Uncontrolled Type 2 Diabetes: The DUAL V Randomized Clinical Trial.
    JAMA, 2016, Mar-01, Volume: 315, Issue:9

    Topics: Diabetes Mellitus, Type 2; Female; Glycated Hemoglobin; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin Glargine; Insulin, Long-Acting; Male; Metformin; Middle Aged; Weight Gain; Weight Loss

2016
Effect of adding insulin degludec to treatment in patients with type 2 diabetes inadequately controlled with metformin and liraglutide: a double-blind randomized controlled trial (BEGIN: ADD TO GLP-1 Study).
    Diabetes, obesity & metabolism, 2016, Volume: 18, Issue:7

    Topics: Blood Glucose; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Therapy, Combination; Fasting; Female; Glycated Hemoglobin; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin, Long-Acting; Liraglutide; Male; Metformin; Middle Aged; Treatment Outcome

2016
Insulin degludec/insulin aspart versus biphasic insulin aspart 30 twice daily in insulin-experienced Japanese subjects with uncontrolled type 2 diabetes: Subgroup analysis of a Pan-Asian, treat-to-target Phase 3 Trial.
    Journal of diabetes, 2017, Volume: 9, Issue:3

    Topics: Aged; Asian People; Biphasic Insulins; Blood Glucose; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Drug Administration Schedule; Drug Therapy, Combination; Female; Glycated Hemoglobin; Humans; Hypertension; Hypoglycemic Agents; Insulin Aspart; Insulin, Isophane; Insulin, Long-Acting; Male; Metformin; Middle Aged; Nasopharyngitis; Treatment Outcome

2017
A Multinational, Randomized, Open-label, Treat-to-Target Trial Comparing Insulin Degludec and Insulin Glargine in Insulin-Naïve Patients with Type 2 Diabetes Mellitus.
    Drugs in R&D, 2016, Volume: 16, Issue:2

    Topics: Blood Glucose; China; Diabetes Mellitus, Type 2; Female; Glycated Hemoglobin; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Insulin Glargine; Insulin, Long-Acting; Male; Metformin; Middle Aged; Treatment Outcome

2016
Cross-Over Study Comparing Postprandial Glycemic Increase After Addition of a Fixed-Dose Mitiglinide/Voglibose Combination or a Dipeptidyl Peptidase-4 Inhibitor to Basal Insulin Therapy in Patients with Type 2 Diabetes Mellitus.
    Medical science monitor basic research, 2017, Feb-28, Volume: 23

    Topics: Aged; Blood Glucose; Cross-Over Studies; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Humans; Hypoglycemic Agents; Inositol; Insulin; Insulin, Long-Acting; Isoindoles; Linagliptin; Male; Metformin; Middle Aged; Postprandial Period

2017
Insulin degludec/liraglutide (IDegLira) was effective across a range of dysglycaemia and body mass index categories in the DUAL V randomized trial.
    Diabetes, obesity & metabolism, 2018, Volume: 20, Issue:1

    Topics: Anti-Obesity Agents; Blood Glucose; Body Mass Index; Diabetes Mellitus, Type 2; Drug Combinations; Drug Monitoring; Drug Resistance, Multiple; Drug Therapy, Combination; Glycated Hemoglobin; Humans; Hyperglycemia; Hypoglycemia; Hypoglycemic Agents; Incretins; Insulin Glargine; Insulin, Long-Acting; Liraglutide; Metformin; Obesity; Overweight; Weight Gain; Weight Loss

2018

Other Studies

4 other study(ies) available for metformin and insulin degludec

ArticleYear
[Medicines for type 2 diabetes: fine tuning rather than redesign].
    Medizinische Monatsschrift fur Pharmazeuten, 2012, Volume: 35, Issue:5

    Topics: Diabetes Mellitus, Type 2; Drug Design; Humans; Hypoglycemic Agents; Insulin, Long-Acting; Metformin

2012
[Optimizing treatment of type 2 diabetic patients].
    MMW Fortschritte der Medizin, 2015, Jun-11, Volume: 157, Issue:11

    Topics: Administration, Oral; Diabetes Mellitus, Type 2; Drug Combinations; Germany; Glucagon-Like Peptide 1; Glycated Hemoglobin; Humans; Injections, Subcutaneous; Insulin, Long-Acting; Liraglutide; Metformin

2015
A patient centred approach to basal insulin choice for the management of type 2 diabetes mellitus.
    JPMA. The Journal of the Pakistan Medical Association, 2016, Volume: 66, Issue:3

    Topics: Checklist; Clinical Decision-Making; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Humans; Hypoglycemic Agents; Insulin; Insulin Detemir; Insulin Glargine; Insulin, Isophane; Insulin, Long-Acting; Metformin; Patient-Centered Care

2016
Hyperglycaemic hyperosmolar state in an obese prepubertal girl with type 2 diabetes: case report and critical approach to diagnosis and therapy.
    Italian journal of pediatrics, 2021, Feb-18, Volume: 47, Issue:1

    Topics: Blood Glucose; Child; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Hyperglycemic Hyperosmolar Nonketotic Coma; Insulin, Long-Acting; Metformin; Pediatric Obesity

2021