metformin and glutaminase

metformin has been researched along with glutaminase in 8 studies

Research

Studies (8)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (12.50)	29.6817
2010's	7 (87.50)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Carlson, OD; Charles, CP; Chia, CW; Egan, JM; Kim, HS; Kim, W; Melvin, DL; Shin, YK	1
Ampuero, J; Bautista, JD; Camacho, I; del Campo, JA; Díaz-Herrero, Mdel M; Figueruela, B; Maraver, M; Nuñez, D; Ranchal, I; Rojas, Á; Romero-Gómez, M	1
Alt, J; Chen, B; Elgogary, A; Fu, J; Hanes, J; Hartung, T; Le, A; Lee, R; Liu, Y; Neisser, M; Nguyen, C; Park, JK; Poore, B; Rais, R; Reyes, J; Rojas, C; Semenza, GL; Slusher, BS; Tsukamoto, T; Xia, S; Xu, Q; Zhao, L; Zimmermann, SC	1
Ampuero, J; Gallego-Durán, R; García-Valdecasas, M; Gil-GÓmez, A; Gómez-Sotelo, AI; Muñoz-Hernández, R; Ranchal, I; Rojas, Á; Romero Gómez, M	1
Addie, RD; Bovée, JVMG; Cleton-Jansen, AM; Cleven, AHG; de Jong, Y; Kruisselbrink, AB; Molenaar, RJ; Niessen, B; Peterse, EFP; van den Akker, BEWM	1
Aventaggiato, M; Barreca, F; Morgante, E; Russo, MA; Saladini, S; Sansone, L; Tafani, M	1
Bass, AJ; Beeson, CC; Beeson, GC; Diehl, JA; Ogretmen, B; Oleinik, N; Parnham, S; Qie, S; Rustgi, AK; Wong, KK; Yoshida, A	1
Guo, Y; Li, X; Lu, C; Luo, L; Paul, B; Saxena, D; Seo, W; Wang, Y; Yan, W; Yang, J; Zhang, R	1

Trials

1 trial(s) available for metformin and glutaminase

Article	Year
Exogenous glucose-dependent insulinotropic polypeptide worsens post prandial hyperglycemia in type 2 diabetes. Diabetes, 2009, Volume: 58, Issue:6 Topics: Area Under Curve; Blood Glucose; Cross-Over Studies; Cyclic AMP; Diabetes Mellitus, Type 2; Diet, Diabetic; Glucagon; Glutaminase; Humans; Hyperglycemia; Hypoglycemic Agents; Immunohistochemistry; Intracellular Signaling Peptides and Proteins; Metformin; Placebos; Postprandial Period; Sulfonylurea Compounds	2009

Article

Year

Exogenous glucose-dependent insulinotropic polypeptide worsens post prandial hyperglycemia in type 2 diabetes.

Diabetes, 2009, Volume: 58, Issue:6

Topics: Area Under Curve; Blood Glucose; Cross-Over Studies; Cyclic AMP; Diabetes Mellitus, Type 2; Diet, Diabetic; Glucagon; Glutaminase; Humans; Hyperglycemia; Hypoglycemic Agents; Immunohistochemistry; Intracellular Signaling Peptides and Proteins; Metformin; Placebos; Postprandial Period; Sulfonylurea Compounds

2009

Other Studies

7 other study(ies) available for metformin and glutaminase

Article	Year
Metformin inhibits glutaminase activity and protects against hepatic encephalopathy. PloS one, 2012, Volume: 7, Issue:11 Topics: Age Factors; Ammonia; Diabetes Complications; Enzyme Inhibitors; Female; Glutaminase; Hepatic Encephalopathy; Humans; Liver Cirrhosis; Male; Metformin; Retrospective Studies; Sex Factors; Spain	2012
Combination therapy with BPTES nanoparticles and metformin targets the metabolic heterogeneity of pancreatic cancer. Proceedings of the National Academy of Sciences of the United States of America, 2016, 09-06, Volume: 113, Issue:36 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Benzeneacetamides; Cell Line, Tumor; Glutaminase; Glutamine; Humans; Metformin; Mice; Nanoparticles; Pancreatic Neoplasms; Proto-Oncogene Proteins p21(ras); Sulfides; Thiadiazoles; Xenograft Model Antitumor Assays	2016
Metformin modifies glutamine metabolism in an in vitro and in vivo model of hepatic encephalopathy. Revista espanola de enfermedades digestivas, 2018, Volume: 110, Issue:7 Topics: Ammonia; Animals; Caco-2 Cells; Child, Preschool; Glutaminase; Glutamine; Hepatic Encephalopathy; Humans; Hypoglycemic Agents; Male; Metformin; Rats; Rats, Wistar	2018
Targeting glutaminolysis in chondrosarcoma in context of the IDH1/2 mutation. British journal of cancer, 2018, Volume: 118, Issue:8 Topics: Antineoplastic Agents; Benzeneacetamides; Bone Neoplasms; Chloroquine; Chondrosarcoma; Drug Screening Assays, Antitumor; Glutaminase; Glutamine; Humans; Immunohistochemistry; Isocitrate Dehydrogenase; Metabolic Networks and Pathways; Metformin; Molecular Targeted Therapy; Mutation; Neoplasm Grading; Thiadiazoles; Tumor Cells, Cultured	2018
Metformin Impairs Glutamine Metabolism and Autophagy in Tumour Cells. Cells, 2019, 01-14, Volume: 8, Issue:1 Topics: Adaptor Proteins, Signal Transducing; Ammonia; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Cisplatin; Glutaminase; Glutamine; HeLa Cells; Humans; MCF-7 Cells; Metformin; Microtubule-Associated Proteins; Neoadjuvant Therapy	2019
Targeting glutamine-addiction and overcoming CDK4/6 inhibitor resistance in human esophageal squamous cell carcinoma. Nature communications, 2019, 03-21, Volume: 10, Issue:1 Topics: Animals; Antineoplastic Agents; Benzeneacetamides; Cell Line, Tumor; Cyclin D1; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase 6; Drug Resistance, Neoplasm; Drug Synergism; Energy Metabolism; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; F-Box Proteins; Gene Expression Regulation, Neoplastic; Glutaminase; Glutamine; Humans; Hypoglycemic Agents; Male; Mechanistic Target of Rapamycin Complex 1; Metformin; Mice; Molecular Targeted Therapy; Phenformin; Protein Kinase Inhibitors; Retinoblastoma Protein; Signal Transduction; Thiadiazoles; Xenograft Model Antitumor Assays	2019
Targeting cellular metabolism to reduce head and neck cancer growth. Scientific reports, 2019, 03-21, Volume: 9, Issue:1 Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Disease-Free Survival; Drug Synergism; Gene Expression Regulation, Neoplastic; Glutaminase; Glutamine; Head and Neck Neoplasms; Humans; Metabolic Networks and Pathways; Metformin; Sulfides; Thiadiazoles	2019