Compounds > metformin

metformin and gentamicin

metformin has been researched along with gentamicin in 12 studies

Research

Studies (12)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	12 (100.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Arévalo, M; Briones, E; Detaille, D; El-Mir, MY; Leverve, X; López-Novoa, JM; Morales, AI; Prieto, M; Puente, A	1
Zorov, DB	1
Chae, SW; Chang, J; Choi, J; Im, GJ; Jung, HH; Yang, JY	1
Lee, JA; Li, YC; Shih, YM	1
Chin, YW; Choi, YH; Lee, YK	1
Kendall, A; Oishi, N; Schacht, J	1
Bakhtiar, S; Janjua, A; Waheed, A	1
Chen, SM; Chou, CK; Lee, JA; Li, YC; Shih, YM	1
Bodmer, D; Brand, Y; Glutz, A; Leitmeyer, K; Setz, C	1
Gai, Z; Hiller, C; Krajnc, E; Kullak-Ublick, GA; Li, T; Visentin, M; Zhen, J	1
Luo, X; Ma, YR; Wu, XA; Wu, YF; Zhang, F; Zhang, GQ; Zhang, T	1
Cao, L; Han, J; Kumar Sah, S; Xie, Y; Zhi, D	1

Reviews

1 review(s) available for metformin and gentamicin

Article	Year
Amelioration of aminoglycoside nephrotoxicity requires protection of renal mitochondria. Kidney international, 2010, Volume: 77, Issue:10 Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Cell Death; Gentamicins; Hypoglycemic Agents; Kidney; Kidney Diseases; Metformin; Mitochondria; Oxidative Stress; Rats	2010

Other Studies

11 other study(ies) available for metformin and gentamicin

Article	Year
Metformin prevents experimental gentamicin-induced nephropathy by a mitochondria-dependent pathway. Kidney international, 2010, Volume: 77, Issue:10 Topics: Acetylglucosaminidase; Animals; Antioxidants; Apoptosis; Cytochrome c Group; Cytochromes c; Electron Transport; Gentamicins; Hypoglycemic Agents; Kidney; Kidney Diseases; Lipid Peroxidation; Male; Metformin; Mitochondria; Oxidation-Reduction; Oxidative Stress; Permeability; Rats; Reactive Oxygen Species	2010
Protective role of antidiabetic drug metformin against gentamicin induced apoptosis in auditory cell line. Hearing research, 2011, Volume: 282, Issue:1-2 Topics: Animals; Apoptosis; Blotting, Western; Calcium; Caspase 3; Cell Line; Cell Survival; Cytoprotection; Gentamicins; Hypoglycemic Agents; Metformin; Mice; Molecular Imaging; Organ of Corti; Poly(ADP-ribose) Polymerases; Reactive Oxygen Species	2011
Gentamicin caused renal injury deeply related to methylglyoxal and N(ɛ)-(carboxyethyl)lysine (CEL). Toxicology letters, 2013, May-10, Volume: 219, Issue:1 Topics: Animals; Anti-Bacterial Agents; Antioxidants; Gentamicins; Glutathione; Immunohistochemistry; Kidney Diseases; Kidney Function Tests; Lysine; Male; Metformin; Pyruvaldehyde; Rats; Rats, Wistar	2013
Effects of Korean red ginseng extract on acute renal failure induced by gentamicin and pharmacokinetic changes by metformin in rats. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2013, Volume: 59 Topics: Acute Kidney Injury; Animals; Anti-Bacterial Agents; Drug Interactions; Gentamicins; Ginsenosides; Hypoglycemic Agents; Intestinal Mucosa; Intestines; Kidney; Liver; Male; Metformin; Microsomes; Panax; Phytotherapy; Plant Extracts; Plant Roots; Protective Agents; Random Allocation; Rats; Rats, Sprague-Dawley; Tissue Distribution	2013
Metformin protects against gentamicin-induced hair cell death in vitro but not ototoxicity in vivo. Neuroscience letters, 2014, Nov-07, Volume: 583 Topics: Animals; Anti-Bacterial Agents; Female; Gentamicins; Guinea Pigs; Hair Cells, Auditory; Hypoglycemic Agents; In Vitro Techniques; Male; Metformin; Mice, Inbred CBA	2014
Protective effect of metformin against gentamicin induced nephrotoxicity in rabbits. Pakistan journal of pharmaceutical sciences, 2014, Volume: 27, Issue:6 Topics: Animals; Anti-Bacterial Agents; Female; Gentamicins; Hypoglycemic Agents; Kidney; Male; Metformin; Rabbits	2014
Chitosan Prevents Gentamicin-Induced Nephrotoxicity via a Carbonyl Stress-Dependent Pathway. BioMed research international, 2015, Volume: 2015 Topics: Animals; Blood Urea Nitrogen; Chitosan; Gentamicins; Humans; Kidney; Kidney Diseases; Metabolic Networks and Pathways; Metformin; Oxidative Stress; Pyruvaldehyde; Rats; Renal Dialysis	2015
Metformin Protects Auditory Hair Cells from Gentamicin-Induced Toxicity in vitro. Audiology & neuro-otology, 2015, Volume: 20, Issue:6 Topics: Animals; Apoptosis; Cell Survival; Gentamicins; Hair Cells, Auditory; Hypoglycemic Agents; In Vitro Techniques; Metformin; Neurites; Neurons; Protein Synthesis Inhibitors; Rats; Rats, Wistar; Spiral Ganglion	2015
Organic Cation Transporter 2 Overexpression May Confer an Increased Risk of Gentamicin-Induced Nephrotoxicity. Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:9 Topics: Animals; Cell Line; Diet, High-Fat; Female; Gentamicins; HEK293 Cells; Humans; Kidney; Kidney Diseases; Kinetics; Male; Metformin; Mice; Mice, Inbred C57BL; Middle Aged; Obesity; Organic Cation Transport Proteins; RNA, Messenger	2016
Alteration of renal excretion pathways in gentamicin-induced renal injury in rats. Journal of applied toxicology : JAT, 2018, Volume: 38, Issue:7 Topics: Acute Kidney Injury; Animals; Antiporters; ATP Binding Cassette Transporter, Subfamily G, Member 2; Disease Models, Animal; Furosemide; Gentamicins; Glomerular Filtration Rate; Inulin; Kidney; Male; Membrane Transport Proteins; Metformin; Multidrug Resistance-Associated Proteins; Organic Cation Transport Proteins; p-Aminohippuric Acid; Rats, Wistar; Renal Elimination	2018
Combinational effect of curcumin and metformin against gentamicin-induced nephrotoxicity: Involvement of antioxidative, anti-inflammatory and antiapoptotic pathway. Journal of food biochemistry, 2019, Volume: 43, Issue:7 Topics: Acute Kidney Injury; Animals; Anti-Inflammatory Agents; Apoptosis; Curcumin; Drug Combinations; Gentamicins; Kidney; Metformin; Oxidative Stress; Rats; Rats, Wistar	2019