metformin and galactose

metformin has been researched along with galactose in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19901 (5.88)18.7374
1990's0 (0.00)18.2507
2000's1 (5.88)29.6817
2010's7 (41.18)24.3611
2020's8 (47.06)2.80

Authors

AuthorsStudies
Adikwu, MU; Takada, K; Yoshikawa, Y1
Attia, A; El-Shenawy, S; Gomaa, N; Hassan, A; Hegazy, R; Kenawy, S; Zaki, H1
Huang, W; Li, S; Li, Y; Ma, L; Niu, H; Wei, Z; Xin, G; Xing, Z; Xu, Y; Zeng, Z1
Allahtavakoli, M; Fatemi, I; Hakimizadeh, E; Heydari, S; Kaeidi, A; Khaluoi, A; Shamsizadeh, A1
Askari, VR; Mousavi, SH; Rahimi, VB1
Askari, VR; Baradaran Rahimi, V; Mousavi, SH1
Cai, H; Chen, X; Han, B; He, Z; Hu, Y; Kong, W; Kong, WJ; Li, Y; Sun, H; Yang, X; Yuan, J; Zhao, X1
Anima, B; Gurusubramanian, G; Jeremy, M; Kharwar, RK; Pankaj, PP; Rempuia, V; Roy, VK1
Chai, YR; Su, Q; Sun, Y; Yang, SP; Zhang, YR1
Alvarez-Iglesias, A; Browne, M; Devane, D; Dunne, F; Gillespie, P; Newman, C; O'Donnell, M; Smyth, A1
Abo-Elsoud, RAA; Ameen, O; Samaka, RM1
Hu, Y; Liu, S; Song, Q; Yan, C1
Hayes, GR; Jacobs, DB; Lockwood, DH; Truglia, JA1
Cai, J; Hu, H; Huang, M; Li, Y; Song, J; Tian, N; Wang, Y; Wu, C; Xing, Q1
Abdel-Rahman, RF; El-Gamil, MA; El-Ridy, MS; Elsayed, I; Yehia, SA; Younis, MM1
Al-Shoubki, AA; Donia, AA; Mady, OY; Qasim, W1
Al-Shoubki, AA; Donia, AA; Mady, OY1

Trials

1 trial(s) available for metformin and galactose

ArticleYear
A randomised placebo-controlled trial of the effectiveness of early metformin in addition to usual care in the reduction of gestational diabetes mellitus effects (EMERGE): study protocol.
    Trials, 2022, Sep-21, Volume: 23, Issue:1

    Topics: Blood Glucose; Clinical Trials, Phase III as Topic; Diabetes, Gestational; Female; Galactose; Gestational Weight Gain; Humans; Hypoglycemia; Infant, Newborn; Insulin; Metformin; Pregnancy; Quality of Life; Randomized Controlled Trials as Topic; Weight Gain

2022

Other Studies

16 other study(ies) available for metformin and galactose

ArticleYear
Pharmacodynamic-pharmacokinetic profiles of metformin hydrochloride from a mucoadhesive formulation of a polysaccharide with antidiabetic property in streptozotocin-induced diabetic rat models.
    Biomaterials, 2004, Volume: 25, Issue:15

    Topics: Adhesiveness; Animals; Blood Glucose; Chemistry, Pharmaceutical; Culture Techniques; Diabetes Mellitus, Experimental; Drug Compounding; Drug Delivery Systems; Excipients; Galactose; Hypoglycemic Agents; Intestinal Mucosa; Male; Metformin; Plant Gums; Rats; Rats, Wistar; Streptozocin; Tensile Strength; Tissue Adhesives; Treatment Outcome

2004
Involvement of insulin resistance in D-galactose-induced age-related dementia in rats: Protective role of metformin and saxagliptin.
    PloS one, 2017, Volume: 12, Issue:8

    Topics: Adamantane; Aging; Animals; Biomarkers; Body Weight; Brain; Dementia; Dipeptides; Galactose; Glycated Hemoglobin; Hypoglycemic Agents; Insulin Resistance; Locomotion; Male; Metformin; Nerve Tissue Proteins; Oxidative Stress; Rats; Rats, Wistar; Reaction Time

2017
d-galactose induces premature senescence of lens epithelial cells by disturbing autophagy flux and mitochondrial functions.
    Toxicology letters, 2018, Jun-01, Volume: 289

    Topics: Adenosine Triphosphate; Antioxidants; Autophagy; Calcium Signaling; Cataract; Cell Line; Cell Proliferation; Cellular Senescence; Eye Proteins; Galactose; Gene Expression Regulation; Humans; Hypoglycemic Agents; Lens, Crystalline; Membrane Potential, Mitochondrial; Metformin; Mitochondria; Oxidative Stress; Reactive Oxygen Species

2018
Metformin ameliorates the age-related changes of d-galactose administration in ovariectomized mice.
    Fundamental & clinical pharmacology, 2018, Volume: 32, Issue:4

    Topics: Aging; Animals; Anti-Inflammatory Agents; Antioxidants; Brain; Brain-Derived Neurotrophic Factor; Female; Galactose; Maze Learning; Metformin; Mice; Neuroprotective Agents; Ovariectomy; Superoxide Dismutase

2018
Ellagic acid reveals promising anti-aging effects against d-galactose-induced aging on human neuroblastoma cell line, SH-SY5Y: A mechanistic study.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 108

    Topics: Aging; Anilides; beta-Galactosidase; Cell Line, Tumor; Cell Proliferation; Cellular Senescence; Ellagic Acid; Galactose; Glutathione; Glycation End Products, Advanced; Humans; Malondialdehyde; Mannitol; Metformin; Neuroblastoma; Protoporphyrins; Reactive Oxygen Species; Tumor Necrosis Factor-alpha

2018
Ellagic acid dose and time-dependently abrogates d-galactose-induced animal model of aging: Investigating the role of PPAR-γ.
    Life sciences, 2019, Sep-01, Volume: 232

    Topics: Aging; Anilides; Animals; Apoptosis; Brain; Ellagic Acid; Galactose; Glutathione Peroxidase; Liver; Male; Malondialdehyde; Metformin; Mice; Models, Animal; Oxidative Stress; PPAR gamma; Superoxide Dismutase; Tumor Necrosis Factor-alpha

2019
Metformin attenuates the D‑galactose‑induced aging process via the UPR through the AMPK/ERK1/2 signaling pathways.
    International journal of molecular medicine, 2020, Volume: 45, Issue:3

    Topics: Aging; AMP-Activated Protein Kinases; Animals; Antioxidants; Apoptosis; Auditory Cortex; Disease Models, Animal; Galactose; Male; MAP Kinase Signaling System; Metformin; Oxidative Stress; PC12 Cells; Presbycusis; Rats; Rats, Sprague-Dawley; Unfolded Protein Response

2020
Effects of metformin on the uterus of d-galactose-induced aging mice: Histomorphometric, immunohistochemical localization (B-cell lymphoma 2, Bcl2-associated X protein, and active capase3), and oxidative stress study.
    Journal of experimental zoology. Part A, Ecological and integrative physiology, 2022, Volume: 337, Issue:6

    Topics: Aging; Animals; bcl-2-Associated X Protein; Caspase 3; Female; Galactose; Metformin; Mice; Oxidative Stress; Uterus

2022
Metformin ameliorates thymus degeneration of mice by regulating mitochondrial function.
    International immunopharmacology, 2022, Volume: 108

    Topics: Aging; Animals; Cellular Senescence; Galactose; Metformin; Mice; Mitochondria; Thymus Gland

2022
Metformin alleviates neurocognitive impairment in aging via activation of AMPK/BDNF/PI3K pathway.
    Scientific reports, 2022, 10-12, Volume: 12, Issue:1

    Topics: Aging; AMP-Activated Protein Kinases; Animals; Brain-Derived Neurotrophic Factor; Caspase 3; Galactose; Male; Metformin; Oxidative Stress; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-bcl-2; Rats; Saline Solution; Synaptophysin

2022
[Metformin inhibits self-renewal of colorectal cancer stem cells by inhibiting mitochondrial oxidative phosphorylation].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2023, Aug-20, Volume: 43, Issue:8

    Topics: Antibodies; Colorectal Neoplasms; Galactose; Humans; Metformin; Oxidative Phosphorylation; Reactive Oxygen Species

2023
Effects of metformin on insulin receptor tyrosine kinase activity in rat adipocytes.
    Diabetologia, 1986, Volume: 29, Issue:11

    Topics: Adipose Tissue; Animals; Blood Glucose; Hexoses; Male; Metformin; Phosphorylation; Protein-Tyrosine Kinases; Rats; Rats, Inbred Strains; Receptor, Insulin

1986
Improving oral bioavailability of metformin hydrochloride using water-in-oil microemulsions and analysis of phase behavior after dilution.
    International journal of pharmaceutics, 2014, Oct-01, Volume: 473, Issue:1-2

    Topics: Administration, Oral; Animals; Biological Availability; Emulsions; Ethylene Glycols; Glycerides; Glycerol; Hexoses; Hypoglycemic Agents; Intestinal Absorption; Intestinal Mucosa; Linoleic Acids; Male; Metformin; Oleic Acids; Organic Chemicals; Phase Transition; Polysorbates; Rats, Sprague-Dawley; Solubility; Surface-Active Agents; Water

2014
Metformin hydrochloride and wound healing: from nanoformulation to pharmacological evaluation.
    Journal of liposome research, 2019, Volume: 29, Issue:4

    Topics: Administration, Cutaneous; Animals; Blood Glucose; Cholesterol; Delayed-Action Preparations; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Drug Compounding; Drug Liberation; Hexoses; Humans; Hypoglycemic Agents; Liposomes; Male; Metformin; Nanocapsules; Polysorbates; Rats, Wistar; Skin; Tissue Distribution; Wound Healing

2019
Metformin hydrochloride entrapment in sorbitan monostearate for intestinal permeability enhancement and pharmacodynamics.
    Scientific reports, 2021, 10-11, Volume: 11, Issue:1

    Topics: Animals; Cell Membrane Permeability; Excipients; Hexoses; Intestinal Mucosa; Male; Metformin; Rabbits; Surface-Active Agents

2021
An Industrial Procedure for Pharmacodynamic Improvement of Metformin HCl via Granulation with Its Paracellular Pathway Enhancer Using Factorial Experimental Design.
    Drug design, development and therapy, 2021, Volume: 15

    Topics: Animals; Blood Glucose; Crystallization; Diabetes Mellitus, Experimental; Drug Compounding; Hexoses; Hypoglycemic Agents; Male; Metformin; Permeability; Polysorbates; Rabbits; Rats; Rats, Wistar; Surface-Active Agents

2021