metformin has been researched along with folic acid in 67 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (7.46) | 18.7374 |
| 1990's | 3 (4.48) | 18.2507 |
| 2000's | 12 (17.91) | 29.6817 |
| 2010's | 36 (53.73) | 24.3611 |
| 2020's | 11 (16.42) | 2.80 |
| Authors | Studies |
|---|---|
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Bury, J; Carpentier, JL; Lefebvre, P; Luyckx, A | 1 |
| Tomkin, GH | 1 |
| Asp, NG; Berchtold, P; Dahlqvist, A; Gustafson, A | 1 |
| Hadden, DR; Montgomery, DA; Tomkin, GH; Weaver, JA | 1 |
| Smith, OA; Stowers, JM | 1 |
| DeFronzo, RA; Goodman, AM | 1 |
| Bjerve, KS; Carlsen, SM; Følling, I; Grill, V; Refsum, H; Schneede, J | 1 |
| Aarsand, AK; Carlsen, SM | 1 |
| Buysschaert, M; Dramais, AS; Hermans, MP; Wallemacq, PE | 1 |
| Bets, D; Borger van der Burg, B; Donker, AJ; Kooy, A; Lehert, P; Ogterop, JC; Stehouwer, CD; Wulffelé, MG | 1 |
| Brain, AM; Child, DF; Davies, GK; De, P; Harvey, JN; Hudson, PR; Jones, H; Mukherjee, S; Williams, CP | 1 |
| Chattananon, A; Pongchaidecha, M; Srikusalanukul, V; Tanjariyaporn, S | 1 |
| Aslan, E; Bagis, T; Erkanli, S; Haydardedeoglu, B; Kilicdag, EB; Tarim, E; Zeyneloglu, HB | 1 |
| Aslan, E; Bagis, T; Erkanli, S; Haydardedeoglu, B; Kilicdag, EB; Kuscu, E; Simsek, E; Tarim, E | 1 |
| Diakoumopoulou, E; Doulgerakis, D; Katsilambros, N; Kirlaki, E; Kitsou, E; Perrea, D; Psallas, M; Tentolouris, N | 1 |
| Bouzid, C; Essais, O; Ibrahim, H; Machghoul, S; Ouertani, H; Ouni, Z; Zidi, B | 1 |
| Carlsen, SM; Kjøtrød, S; Romundstad, P; Vanky, E | 1 |
| Ning, G; Zhang, YF | 1 |
| Buñuel Granados, JM; Esteban Jiménez, O; González Rubio, F; Navarro Pemán, C | 1 |
| Hidalgo, SF; Prieto de Paula, JM; Salado Valdivieso, I | 1 |
| Colao, A; Falbo, A; Giallauria, F; Orio, F; Palomba, S; Russo, T; Tolino, A; Zullo, F | 1 |
| Benedetto, V; Raffone, E; Rizzo, P | 1 |
| Bets, D; de Jager, J; Donker, AJ; Kooy, A; Lehert, P; Stehouwer, CD; van der Kolk, J; Verburg, J; Wulffelé, MG | 1 |
| Aghamohammadi, V; Aliasgharzadeh, A; Gargari, BP | 1 |
| Cacciapuoti, F | 1 |
| Ali, S; Haq, S; Mohammad, R; Sarkar, FH | 1 |
| Au, C; Cabreiro, F; Cochemé, HM; Gems, D; Greene, ND; Leung, KY; Noori, T; Schuster, E; Vergara-Irigaray, N; Weinkove, D | 1 |
| Alleyassin, A; Fanisalek, M; Hosseini, MA; Kokab, A; Safdarian, L; Sarvi, F | 1 |
| Leulier, F; Storelli, G; Téfit, M | 1 |
| Fang, D; He, X; Huang, Z; Li, Y; Wan, X; Xu, L | 1 |
| Brouwer-Brolsma, EM; de Groot, LC; de Jonge, R; Dhonukshe-Rutten, RA; Enneman, AW; Ham, AC; Lips, P; Oliai Araghi, S; Sohl, E; Stricker, BH; Swart, KM; Uitterlinden, AG; van der Cammen, TJ; van der Velde, N; van der Zwaluw, NL; van Dijk, SC; van Meurs, JB; van Schoor, NM; van Wijngaarden, JP; Witkamp, RF; Zillikens, MC | 1 |
| Asara, JM; German, NJ; Gonzalez-Herrera, KN; Haigis, MC; Janzer, A; Struhl, K | 1 |
| Ahn, YB; Han, KD; Kim, HS; Ko, SH; Park, YM; Song, KH | 1 |
| Ahn, YB; Kang, D; Ko, SH; Lim, TS; Park, YM; Yun, JS | 1 |
| Bostom, AG; Costa, N; Diamantidis, CJ; Gravens-Muller, L; Ivanova, A; Manitpisitkul, W; Weir, MR | 1 |
| Alibrandi, A; Cucinotta, D; Forte, F; Gambadoro, N; Giandalia, A; Perdichizzi, G; Romeo, EL; Russo, GT; Scarcella, C; Zingale, R | 1 |
| Abd-Allah, GM; Hassan, MH | 1 |
| Behera, J; Jeremic, N; Majumder, A; Tyagi, SC | 1 |
| Defeudis, G; Del Toro, R; Fioriti, E; Guglielmi, C; Kyanvash, S; Maggi, D; Manfrini, S; Maurizi, AR; Menduni, M; Pantano, AL; Pozzilli, P | 1 |
| Nas, K; Tűű, L | 1 |
| Olgun, A | 1 |
| Cao, Q; Chen, J; Chen, XM; Huang, C; Pollock, CA; Shi, Y; Yi, H; Zhang, L; Zhao, Y | 1 |
| Wang, S; Xiao, Y; Yin, Z; Zong, Q | 1 |
| Farquhar, C; Hodgson, R; Jordan, V; Mackenzie-Proctor, R; Showell, MG | 1 |
| Brassill, MJ; Brosnan, E; Carmody, L; Clarke, H; Coogan Kelly, C; Culliney, L; Durkan, M; Egan, AM; Fenlon, M; Ferry, P; Hanlon, G; Higgins, T; Hoashi, S; Khamis, A; Kinsley, B; Kinsley, T; Kirwan, B; Liew, A; McGurk, C; McHugh, C; Murphy, MS; Murphy, P; Nolan, M; O'Halloran, D; O'Mahony, L; O'Sullivan, E; P Dunne, F; Peter, M; Roberts, G; Smyth, A; Todd, M; Tuthill, A; Wan Mahmood, WA; Yousif, O | 1 |
| Bazarganipour, F; Kutenaee, MA; Pourghasem, S; Taghavi, SA | 1 |
| Azevedo, A; Faria, J; Martel, F; Negalha, G | 1 |
| Casey, MC; Cunningham, C; Gallagher, AM; Hoey, L; Hughes, CF; Laird, E; McCann, A; McCarroll, K; McNulty, H; Molloy, AM; O'Kane, M; Porter, KM; Strain, S; Tracey, F; Ward, M | 1 |
| Ahn, CW; Fang, S; Kim, J; Lee, HS; Park, JS | 1 |
| Chen, ZX; Cheng, H; Guo, DK; Liu, MD; Wang, SB; Zhang, XZ; Zhong, Z; Zou, MZ | 1 |
| Anadol-Schmitz, E; Bobrov, P; Burkart, V; Kahl, S; Kanti, G; Karusheva, Y; Markgraf, DF; Roden, M; Sarabhai, T; Strassburger, K; Szendroedi, J; Trenkamp, S; Zaharia, OP; Ziegler, D | 1 |
| Haidich, AB; Hatzichristodoulou, G; Hatzichristou, D; Mykoniatis, I; Ouranidis, A; Pyrgidis, N; Sokolakis, I; Sountoulides, P; van Renterghem, K | 1 |
| Bai, Y; Fang, Z; Li, X; Pan, H; Wang, F; Yang, X; Zhang, C | 1 |
| Chen, S; Liu, C; Song, M; Tao, Z; Xia, W; Zhang, W; Zhu, B | 1 |
| Deshpande, S; Gajjar, N; Jethaliya, H; Patel, R; Patel, V | 1 |
| Bilen, A; Bilen, H; Capoglu, I; Ciftel, E; Ciftel, S; Dayanan, R; Kasalı, K; Mercantepe, F; Yanıkoglu, ND | 1 |
| Dadashpour, M; Jafari-Gharabaghlou, D; Khanghah, OJ; Salmani-Javan, E; Zarghami, N | 1 |
| Sultana, R; Wee, AKH | 1 |
| Genc, AC; Genc, FT; Kaya, T; Nalbant, A | 1 |
9 review(s) available for metformin and folic acid
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Mecobalamin.
Topics: Aged; Alprostadil; Animals; Cobamides; Coenzymes; Diabetic Neuropathies; Drug Administration Routes; Drug Therapy, Combination; Female; Folic Acid; Humans; Hyperhomocysteinemia; Hypoglycemic Agents; Kidney Failure, Chronic; Male; Metformin; Methionine; Methyltransferases; Peripheral Nervous System Diseases; Randomized Controlled Trials as Topic; Renal Dialysis; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6 | 2008 |
The complexities of epidemiology and prevention of gastrointestinal cancers.
Topics: Colorectal Neoplasms; Cyclooxygenase 2 Inhibitors; Diabetes Complications; Folic Acid; Gastrointestinal Neoplasms; Humans; Hypoglycemic Agents; Inflammatory Bowel Diseases; Metformin; Obesity; Pancreatic Neoplasms; Smoking | 2012 |
Hypermethylation: Causes and Consequences in Skeletal Muscle Myopathy.
Topics: Animals; DNA Methylation; Epigenesis, Genetic; Folic Acid; Histones; Homocysteine; Humans; Hyperhomocysteinemia; Metformin; Muscle, Skeletal; Muscular Diseases; Oxidative Stress; RNA Interference; Thiazolidinediones; Vitamin B 12; Vitamin B 6 | 2017 |
Inositol for subfertile women with polycystic ovary syndrome.
Topics: Abortion, Spontaneous; Administration, Oral; Birth Rate; Clomiphene; Combined Modality Therapy; Female; Fertility Agents, Female; Fertilization in Vitro; Folic Acid; Humans; Hypoglycemic Agents; Infertility, Female; Inositol; Live Birth; Melatonin; Metformin; Ovulation Induction; Polycystic Ovary Syndrome; Pregnancy; Pregnancy, Multiple; Randomized Controlled Trials as Topic; Vitamin B Complex | 2018 |
Metformin and Breast Cancer: Molecular Targets.
Topics: AMP-Activated Protein Kinases; Animals; Breast Neoplasms; Cell Line, Tumor; Diabetes Mellitus, Type 2; Disease Models, Animal; Female; Folic Acid; Gene Expression Regulation, Neoplastic; Humans; Hypoglycemic Agents; Incidence; Mechanistic Target of Rapamycin Complex 1; Metabolic Networks and Pathways; Metformin; MicroRNAs; Molecular Targeted Therapy; Oxidative Stress; Reactive Oxygen Species; Signal Transduction; Xenograft Model Antitumor Assays | 2019 |
Assessment of Combination Therapies vs Monotherapy for Erectile Dysfunction: A Systematic Review and Meta-analysis.
Topics: Adrenergic alpha-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antioxidants; Combined Modality Therapy; Drug Therapy, Combination; Equipment and Supplies; Erectile Dysfunction; Extracorporeal Shockwave Therapy; Folic Acid; Humans; Hypoglycemic Agents; Male; Metformin; Phosphodiesterase 5 Inhibitors; Sildenafil Citrate; Tadalafil; Treatment Outcome; Vitamin B Complex | 2021 |
The effect of metformin on homocysteine levels in patients with polycystic ovary syndrome: A systematic review and meta-analysis.
Topics: Female; Folic Acid; Homocysteine; Humans; Hypoglycemic Agents; Metformin; Polycystic Ovary Syndrome | 2021 |
Efficacy of Myo-inositol on Anthropometric, Metabolic, and Endocrine Outcomes in PCOS Patients: a Meta-analysis of Randomized Controlled Trial.
Topics: Female; Folic Acid; Humans; Inositol; Insulin; Insulin Resistance; Metformin; Polycystic Ovary Syndrome; Randomized Controlled Trials as Topic | 2022 |
15 trial(s) available for metformin and folic acid
| Article | Year |
|---|---|
Efficacy of metformin in patients with non-insulin-dependent diabetes mellitus. The Multicenter Metformin Study Group.
Topics: Blood Glucose; Body Weight; Cholesterol; Diabetes Mellitus; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Fasting; Female; Folic Acid; Glucose Tolerance Test; Glyburide; Glycated Hemoglobin; Humans; Insulin; Lactates; Lactic Acid; Male; Metformin; Middle Aged; Obesity; Treatment Failure; Vitamin B 12 | 1995 |
Metformin increases total serum homocysteine levels in non-diabetic male patients with coronary heart disease.
Topics: Adult; Coronary Disease; Cysteine; Folic Acid; Homocysteine; Humans; Hypoglycemic Agents; Male; Metformin; Methylmalonic Acid; Middle Aged; Vitamin B 12 | 1997 |
Folate administration reduces circulating homocysteine levels in NIDDM patients on long-term metformin treatment.
Topics: Cardiovascular Diseases; Diabetes Mellitus, Type 2; Dipeptides; Double-Blind Method; Female; Folic Acid; Hematinics; Homocysteine; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Prospective Studies; Risk Factors; Time Factors; Treatment Outcome; Vitamin B 12 | 1998 |
Effects of short-term treatment with metformin on serum concentrations of homocysteine, folate and vitamin B12 in type 2 diabetes mellitus: a randomized, placebo-controlled trial.
Topics: Adult; Aged; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Administration Schedule; Female; Folic Acid; Homocystine; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Vitamin B 12 | 2003 |
The effect of oral folic acid on glutathione, glycaemia and lipids in Type 2 diabetes.
Topics: Adult; Aged; Albuminuria; Blood Glucose; Blood Pressure; Cholesterol, HDL; Diabetes Mellitus, Type 2; Dietary Supplements; Erythrocytes; Female; Folic Acid; Glutathione; Glycated Hemoglobin; Homocysteine; Humans; Hypoglycemic Agents; Lipids; Male; Metformin; Middle Aged; Triglycerides; Vitamin B 6 | 2004 |
Homocysteine levels in women with polycystic ovary syndrome treated with metformin versus rosiglitazone: a randomized study.
Topics: Adult; Anovulation; Blood Glucose; Body Weight; Female; Folic Acid; Homocysteine; Humans; Hypoglycemic Agents; Insulin Resistance; Lipids; Luteinizing Hormone; Metformin; Polycystic Ovary Syndrome; Rosiglitazone; Testosterone; Thiazolidinediones; Vitamin B 12 | 2005 |
Administration of B-group vitamins reduces circulating homocysteine in polycystic ovarian syndrome patients treated with metformin: a randomized trial.
Topics: Adolescent; Adult; Blood Glucose; Body Weight; Dose-Response Relationship, Drug; Female; Folic Acid; Homocysteine; Humans; Lipids; Menstrual Cycle; Metformin; Ovulation; Polycystic Ovary Syndrome; Vitamin B Complex | 2005 |
Homocysteine levels are unaffected by metformin treatment in both nonpregnant and pregnant women with polycystic ovary syndrome.
Topics: Female; Folic Acid; Homocysteine; Humans; Hypoglycemic Agents; Metformin; Methylenetetrahydrofolate Reductase (NADPH2); Polycystic Ovary Syndrome; Polymorphism, Genetic; Pregnancy; Pregnancy Complications; Prospective Studies; Testosterone; Vitamin B 12 | 2007 |
Insulin sensitiser agents alone and in co-treatment with r-FSH for ovulation induction in PCOS women.
Topics: Adult; Anovulation; Dietary Supplements; Drug Therapy, Combination; Female; Fertility Agents, Female; Folic Acid; Follicle Stimulating Hormone; Humans; Hypoglycemic Agents; Infertility, Female; Inositol; Menstruation Disturbances; Metformin; Ovulation Induction; Polycystic Ovary Syndrome; Pregnancy; Pregnancy Rate; Young Adult | 2010 |
Long term treatment with metformin in patients with type 2 diabetes and risk of vitamin B-12 deficiency: randomised placebo controlled trial.
Topics: Aged; Diabetes Mellitus, Type 2; Female; Folic Acid; Homocysteine; Humans; Hypoglycemic Agents; Long-Term Care; Male; Metformin; Middle Aged; Risk Factors; Vitamin B 12; Vitamin B 12 Deficiency | 2010 |
Effect of folic acid supplementation on homocysteine, serum total antioxidant capacity, and malondialdehyde in patients with type 2 diabetes mellitus.
Topics: Administration, Oral; Aged; Antioxidants; Diabetes Mellitus, Type 2; Dietary Supplements; Dose-Response Relationship, Drug; Double-Blind Method; Folic Acid; Homocysteine; Humans; Male; Malondialdehyde; Metformin; Middle Aged; Oxidative Stress; Vitamin B 12 | 2011 |
Metformin treatment in different phenotypes of polycystic ovary syndrome.
Topics: Adult; Female; Folic Acid; Humans; Hypoglycemic Agents; Insemination, Artificial; Metformin; Ovulation; Ovulation Induction; Phenotype; Polycystic Ovary Syndrome; Pregnancy; Pregnancy Rate; Vitamin B Complex; Young Adult | 2013 |
Effects of metformin plus gliclazide versus metformin plus glimepiride on cardiovascular risk factors in patients with type 2 diabetes mellitus.
Topics: Adult; Aged; Blood Glucose; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Folic Acid; Gliclazide; Glycated Hemoglobin; Homocysteine; Humans; Hypoglycemic Agents; Lipids; Male; Metformin; Middle Aged; Risk Factors; Sulfonylurea Compounds | 2015 |
A pilot study of D-chiro-inositol plus folic acid in overweight patients with type 1 diabetes.
Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Female; Folic Acid; Humans; Inositol; Insulin; Insulin Resistance; Male; Metformin; Middle Aged; Overweight; Pilot Projects; Young Adult | 2017 |
The effectiveness of inositol and metformin on infertile polycystic ovary syndrome women with resistant to letrozole.
Topics: Adult; Female; Folic Acid; Humans; Infertility, Female; Inositol; Letrozole; Metformin; Ovulation Induction; Polycystic Ovary Syndrome; Pregnancy; Single-Blind Method | 2019 |
43 other study(ies) available for metformin and folic acid
| Article | Year |
|---|---|
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Vitamin B 12 and folic acid serum levels in diabetics under various therapeutic regimens.
Topics: Diabetes Mellitus; Female; Folic Acid; Humans; Insulin; Iron; L-Lactate Dehydrogenase; Male; Metformin; Sulfonylurea Compounds; Vitamin B 12 | 1976 |
Malabsorption of vitamin B12 in diabetic patients treated with phenformin: a comparison with metformin.
Topics: Cobalt Isotopes; Diabetes Mellitus; Female; Folic Acid; Hemoglobinometry; Humans; Intestinal Absorption; Male; Metformin; Middle Aged; Phenformin; Schilling Test; Time Factors; Vitamin B 12 | 1973 |
Effects of a biguanide (Metformin) on vitamin B 12 and folic acid absorption and intestinal enzyme activities.
Topics: Adult; Biopsy; Enzyme Activation; Female; Folic Acid; Galactosidases; Humans; Intestinal Absorption; Intestinal Mucosa; Male; Maltose; Metformin; Middle Aged; Sucrase; Trehalase; Vitamin B 12 | 1971 |
Vitamin-B12 status of patients on long-term metformin therapy.
Topics: Aged; Cobalt Isotopes; Diabetes Mellitus; Dietary Fats; Folic Acid; Hemoglobinometry; Humans; Ileum; Intestinal Absorption; Intrinsic Factor; Lipid Metabolism; Malabsorption Syndromes; Metformin; Middle Aged; Radiography; Vitamin B 12 | 1971 |
Vitamin B 12 and metformin.
Topics: Acidosis; Diabetes Mellitus; Folic Acid; Humans; Intestinal Absorption; Lactates; Metformin; Phenformin; Vitamin B 12; Vitamin B 12 Deficiency | 1971 |
Hyperhomocysteinemia in type 2 diabetes: relationship to macroangiopathy, nephropathy, and insulin resistance.
Topics: Aged; Cohort Studies; Creatinine; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Female; Folic Acid; Homeostasis; Homocysteine; Humans; Hyperhomocysteinemia; Hypoglycemic Agents; Insulin; Insulin Resistance; Logistic Models; Male; Metabolic Clearance Rate; Metformin; Middle Aged; Vitamin B 12 | 2000 |
Effect of metformin on plasma homocysteine, vitamin B12 and folic acid: a cross-sectional study in patients with type 2 diabetes mellitus.
Topics: Adult; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Folic Acid; Homocysteine; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Vitamin B 12 | 2004 |
Plasma homocysteine levels in patients with type 2 diabetes in a Mediterranean population: relation with nutritional and other factors.
Topics: Adult; Aged; Alcohol Drinking; Animals; Blood Glucose; Blood Pressure; Coffee; Diabetes Mellitus, Type 2; Diet; Exercise; Female; Fishes; Folic Acid; Fruit; Glomerular Filtration Rate; Glycated Hemoglobin; Homocysteine; Humans; Linear Models; Male; Meat; Mediterranean Region; Metformin; Middle Aged; Nutritional Status; Surveys and Questionnaires; Triglycerides; Vegetables | 2005 |
[Factors influencing homocysteineamia in type 2 diabetic patients].
Topics: Diabetes Mellitus, Type 2; Female; Folic Acid; Glycated Hemoglobin; Homocysteine; Humans; Hyperhomocysteinemia; Hypoglycemic Agents; Male; Metformin; Middle Aged; Obesity; Prospective Studies; Risk Factors; Vitamin B 12; Vitamin B 12 Deficiency | 2006 |
[Vitamin B12 deficiency secondary to metformin therapy].
Topics: Aged; Anemia; Diabetes Mellitus, Type 2; Drug Synergism; Female; Folic Acid; Humans; Hyperhomocysteinemia; Hypoglycemic Agents; Intestinal Absorption; Male; Metformin; Middle Aged; Proton Pump Inhibitors; Retrospective Studies; Vitamin B 12; Vitamin B 12 Deficiency | 2010 |
[Metformin and vitamin B12 deficiency].
Topics: Aged; Anemia; Female; Folic Acid; Humans; Hyperhomocysteinemia; Hypoglycemic Agents; Intestinal Absorption; Metformin; Vitamin B 12; Vitamin B 12 Deficiency | 2010 |
Effects of metformin with or without supplementation with folate on homocysteine levels and vascular endothelium of women with polycystic ovary syndrome.
Topics: Adult; Body Mass Index; Brachial Artery; Double-Blind Method; Endothelin-1; Endothelium, Vascular; Exercise; Female; Folic Acid; Homocysteine; Humans; Hypoglycemic Agents; Leisure Activities; Metformin; Placebos; Polycystic Ovary Syndrome; Tunica Intima; Tunica Media; Vasodilation; Vitamin B 12; Waist-Hip Ratio | 2010 |
Diabetes drug interferes with vitamin B12.
Topics: Diabetes Mellitus, Type 2; Folic Acid; Health Knowledge, Attitudes, Practice; Humans; Hypoglycemic Agents; Metformin; Vitamin B 12; Vitamin B 12 Deficiency | 2010 |
Lowering homocysteine levels may prevent cardiovascular impairments? Possible therapeutic behaviors.
Topics: Acetylcysteine; Aspirin; Blood Vessels; Cardiovascular Diseases; Clopidogrel; Diuretics; Fatty Acids, Omega-3; Folic Acid; Homocysteine; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemic Agents; Metformin; Platelet Aggregation Inhibitors; S-Adenosylmethionine; Ticlopidine; Vitamin B 12; Vitamin B 6 | 2012 |
Metformin retards aging in C. elegans by altering microbial folate and methionine metabolism.
Topics: Adenylate Kinase; Aging; Animals; Biguanides; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Caloric Restriction; Diabetes Mellitus, Type 2; DNA-Binding Proteins; Escherichia coli; Folic Acid; Humans; Hypoglycemic Agents; Longevity; Metagenome; Metformin; Methionine; Transcription Factors | 2013 |
Metformin, microbes, and aging.
Topics: Animals; Caenorhabditis elegans; Folic Acid; Humans; Hypoglycemic Agents; Longevity; Metformin; Methionine | 2013 |
Adverse effect of metformin therapy on serum vitamin B12 and folate: short-term treatment causes disadvantages?
Topics: Folic Acid; Humans; Hypoglycemic Agents; Metformin; Vitamin B 12 | 2013 |
Associations between medication use and homocysteine levels in an older population, and potential mediation by vitamin B12 and folate: data from the B-PROOF Study.
Topics: Aged; Diuretics; Female; Folic Acid; Health Services for the Aged; Homocysteine; Humans; Male; Metformin; Netherlands; Osteoporosis; Population Surveillance; Vitamin B 12; Vitamin B 12 Deficiency | 2014 |
Metformin and phenformin deplete tricarboxylic acid cycle and glycolytic intermediates during cell transformation and NTPs in cancer stem cells.
Topics: Aminoimidazole Carboxamide; Biguanides; Cell Line, Transformed; Cell Line, Tumor; Citric Acid Cycle; Endoplasmic Reticulum; Folic Acid; Glycerophosphates; Glycolysis; Humans; Lactates; Metabolome; Metformin; Neoplastic Stem Cells; Nucleotides; Phenformin; Ribonucleotides; src-Family Kinases; Tamoxifen | 2014 |
Association of vitamin B12 deficiency and metformin use in patients with type 2 diabetes.
Topics: Aged; Area Under Curve; Diabetes Mellitus, Type 2; Female; Folic Acid; Humans; Hypoglycemic Agents; Immunoassay; Male; Metformin; Middle Aged; Odds Ratio; Patients; Prevalence; ROC Curve; Time Factors; Vitamin B 12; Vitamin B 12 Deficiency | 2014 |
Higher prevalence of metformin-induced vitamin B12 deficiency in sulfonylurea combination compared with insulin combination in patients with type 2 diabetes: a cross-sectional study.
Topics: Adult; Aged; Diabetes Mellitus, Type 2; Drug Combinations; Female; Folic Acid; Humans; Insulin; Male; Metformin; Middle Aged; Sulfonylurea Compounds; Vitamin B 12; Vitamin B 12 Deficiency | 2014 |
Safety events in kidney transplant recipients: results from the folic Acid for vascular outcome reduction in transplant trial.
Topics: Adult; Calcineurin Inhibitors; Drug Interactions; Female; Folic Acid; Glomerular Filtration Rate; Humans; Kidney Transplantation; Male; Metformin; Middle Aged; Patient Safety | 2015 |
Diabetic neuropathy is not associated with homocysteine, folate, vitamin B12 levels, and MTHFR C677T mutation in type 2 diabetic outpatients taking metformin.
Topics: Adult; Aged; Aged, 80 and over; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Female; Folic Acid; Follow-Up Studies; Genotype; Homocysteine; Humans; Hypoglycemic Agents; Male; Metformin; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Mutation; Outpatients; Prognosis; Vitamin B 12 | 2016 |
A comparative study between myo-inositol and metformin in the treatment of insulin-resistant women.
Topics: Adult; Body Mass Index; Fasting; Female; Folic Acid; Humans; Inositol; Insulin; Insulin Resistance; Menstruation Disturbances; Metformin; Polycystic Ovary Syndrome; Pregnancy; Pregnancy Rate; Prolactin; Retrospective Studies | 2017 |
"Metformin-resistant" folic acid producing probiotics or folic acid against metformin's adverse effects like diarrhea.
Topics: Animals; Diabetes Mellitus, Type 2; Diarrhea; Directed Molecular Evolution; Folic Acid; Gastrointestinal Microbiome; Humans; Hypoglycemic Agents; Metformin; Models, Biological; Probiotics | 2017 |
Metformin attenuates folic-acid induced renal fibrosis in mice.
Topics: Albuminuria; Animals; Cell Line; Chemokine CCL2; Collagen Type IV; Disease Models, Animal; Extracellular Matrix; Fibronectins; Fibrosis; Folic Acid; Gene Expression Regulation; Humans; Inflammation; Kidney; Kidney Tubules, Proximal; Male; MAP Kinase Signaling System; Metformin; Mice, Inbred C57BL; Smad3 Protein; Transforming Growth Factor beta1 | 2018 |
Co-delivery of Metformin and Paclitaxel Via Folate-Modified pH-Sensitive Micelles for Enhanced Anti-tumor Efficacy.
Topics: Animals; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Line, Tumor; Drug Carriers; Drug Delivery Systems; Female; Folic Acid; Humans; Hydrogen-Ion Concentration; Metformin; Mice; Mice, Inbred BALB C; Micelles; Paclitaxel; Treatment Outcome; Tumor Burden; Xenograft Model Antitumor Assays | 2018 |
An Irish National Diabetes in Pregnancy Audit: aiming for best outcomes for women with diabetes.
Topics: Abortion, Spontaneous; Adult; Aspirin; Cesarean Section; Clinical Audit; Delivery of Health Care; Delivery, Obstetric; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Female; Fetal Macrosomia; Folic Acid; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Infant, Newborn; Infusion Pumps, Implantable; Insulin; Insulin Infusion Systems; Intensive Care Units, Neonatal; Ireland; Live Birth; Mass Screening; Metformin; Platelet Aggregation Inhibitors; Preconception Care; Pregnancy; Pregnancy in Diabetics; Pregnancy Outcome; Premature Birth; Retrospective Studies; Stillbirth; Vitamin B Complex | 2020 |
Hyperglycemia and Metformin Use Are Associated With B Vitamin Deficiency and Cognitive Dysfunction in Older Adults.
Topics: Aged; Aged, 80 and over; Cognitive Dysfunction; Cohort Studies; Female; Folic Acid; Geriatric Assessment; Humans; Hyperglycemia; Independent Living; Male; Metformin; Risk Factors; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6 | 2019 |
Association between metformin dose and vitamin B12 deficiency in patients with type 2 diabetes.
Topics: Age Factors; Aged; Alcohol Drinking; Anemia; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Female; Folic Acid; Homocysteine; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Odds Ratio; Republic of Korea; Time Factors; Vitamin B 12; Vitamin B 12 Deficiency; Vitamins | 2019 |
A MSN-based tumor-targeted nanoplatform to interfere with lactate metabolism to induce tumor cell acidosis for tumor suppression and anti-metastasis.
Topics: Antineoplastic Agents; Cell Line, Tumor; Fluvastatin; Folic Acid; Humans; Lactates; Manganese Compounds; Metformin; Nanoparticles; Neoplasm Metastasis; Neoplasms; Porosity; Silicon; Tumor Microenvironment | 2020 |
Vitamin B12 and Folate Concentrations in Recent-onset Type 2 Diabetes and the Effect of Metformin Treatment.
Topics: Adolescent; Adult; Aged; Biomarkers; Blood Glucose; Cross-Sectional Studies; Diabetes Mellitus, Type 1; Female; Folic Acid; Folic Acid Deficiency; Follow-Up Studies; Humans; Hypoglycemic Agents; Insulin Resistance; Male; Metformin; Middle Aged; Prognosis; Prospective Studies; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult | 2020 |
Self-assembled polymeric nanocarrier-mediated co-delivery of metformin and doxorubicin for melanoma therapy.
Topics: Animals; Apoptosis; Cell Survival; Chemistry, Pharmaceutical; Cholesterol; Doxorubicin; Drug Carriers; Drug Combinations; Drug Liberation; Folic Acid; Glucose-6-Phosphate Isomerase; Humans; Hydrogen-Ion Concentration; Male; Melanoma; Metformin; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Nanoparticles; Skin Neoplasms | 2021 |
Vitamin B12, folic acid, vitamin D, iron, ferritin, magnesium, and HbA1c levels in patients with diabetes mellitus and dental prosthesis.
Topics: Case-Control Studies; Dental Prosthesis; Diabetes Mellitus; Ferritins; Folic Acid; Glycated Hemoglobin; Humans; Iron; Magnesium; Metformin; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin D; Vitamins | 2022 |
Potentiation of Folate-Functionalized PLGA-PEG nanoparticles loaded with metformin for the treatment of breast Cancer: possible clinical application.
Topics: Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Drug Carriers; Female; Folic Acid; Humans; Metformin; Nanoparticles; Polyethylene Glycols | 2023 |
Determinants of vitamin B12 deficiency in patients with type-2 diabetes mellitus - A primary-care retrospective cohort study.
Topics: Aged; Aged, 80 and over; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Folic Acid; Humans; Hypoglycemic Agents; Metformin; Retrospective Studies; Vitamin B 12; Vitamin B 12 Deficiency | 2023 |
Effect of a combination of gliptin and metformin on serum vitamin B12, folic acid, and ferritin levels.
Topics: Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Ferritins; Folic Acid; Humans; Hypoglycemic Agents; Metformin; Vitamin B 12 | 2023 |