metformin and ethinyl estradiol

metformin has been researched along with ethinyl estradiol in 85 studies

Research

Studies (85)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	30 (35.29)	29.6817
2010's	48 (56.47)	24.3611
2020's	7 (8.24)	2.80

Authors

Authors	Studies
Lombardo, F; Obach, RS; Waters, NJ	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Campillo, NE; Guerra, A; Páez, JA	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Glen, RC; Lowe, R; Mitchell, JB	1
Ekins, S; Williams, AJ; Xu, JJ	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Giacomini, KM; Huang, Y; Khuri, N; Kido, Y; Kosaka, A; Morrissey, KM; Sali, A; Wittwer, MB; Zhang, X; Zur, AA	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Koivunen, RM; Martikainen, HK; Morin-Papunen, LC; Ruokonen, A; Tapanainen, JS; Vauhkonen, I	1
Durmusoglu, F; Elter, K; Imir, G	1
Koivunen, R; Martikainen, H; Morin-Papunen, L; Ruokonen, A; Tapanainen, JS; Vauhkonen, I	1
Fleming, R; Harborne, L; Lyall, H; Norman, J; Sattar, N	1
Hedberg, P; Morin-Papunen, L; Puukka, M; Rautio, K; Ruokonen, A; Tapanainen, JS	1
de Zegher, F; Ibáñez, L	3
Kelestimur, F; Sahin, Y	1
Mitkov, M; Pekhlivanov, B; Terzieva, D	1
Cabré, S; De Zegher, F; Ibáñez, L; Valls, C	1
Mitkov, M; Pehlivanov, B; Terzieva, D	1
Morin-Papunen, LC; Rautio, K; Ruokonen, A; Tapanainen, JS	1
Al-Inany, H	2
Alvarez-Blasco, F; Botella-Carretero, JI; Escobar-Morreale, HF; Lasunción, MA; Luque-Ramírez, M; Martínez-Bermejo, E	1
Atanasova, I; Genchev, G; Kamenov, Z; Khristov, V; Kolarov, G; Milcheva, B; Orbetsova, M; Shigarminova, R; Zakharieva, S	1
Alvarez-Blasco, F; Botella-Carretero, JI; Escobar-Morreale, HF; Luque-Ramírez, M; San Millán, JL; Sanchón, R	1
Baser, I; Dede, M; Erbil, MK; Kenar, L; Oktenli, C; Ozgurtas, T; Sanisoglu, SY; Tapan, S; Yenen, MC; Yesilova, Z	1
Alvarez-Blasco, F; Escobar-Morreale, HF; Luque-Ramírez, M; Uriol Rivera, MG	1
Harrison, C; Hutchison, SK; Meyer, C; Stepto, N; Teede, HJ	1
Jiang, M; Ma, F; Qi, J; Qiao, L; Wang, L; Xie, S; Xu, K; Yue, H; Zhang, W; Zhou, X	1
Alvarez-Blasco, F; Escobar-Morreale, HF; Luque-Ramírez, M; Mendieta-Azcona, C	1
Cao, Y; Jiang, Y; Wu, J; Zhu, Y	1
Choi, MK; Chung, SJ; Hong, SS; Jin, HE; Kim, DD; Maeng, HJ; Shim, CK	1
Jing, Z; Liang-Zhi, X; Tai-Xiang, W; Ying, T; Yu-Jian, J	1
Hutchison, SK; McGrath, BP; Meyer, C; Moran, LJ; Teede, HJ; Zoungas, S	1
del Rey Sánchez, JM; Escobar-Morreale, HF; Luque-Ramírez, M; Matíes, M; Mendieta-Azcona, C	1
Alacacioglu, A; Kebapcilar, AG; Kebapcilar, L; Sari, I; Taner, CE	1
Bilgir, F; Bilgir, O; Bozkaya, G; Kebapcilar, A; Kebapcilar, L; Sari, I; Taner, C; Yildiz, Y; Yuksel, A	1
Fruzzetti, F; Gambacciani, M; Genazzani, AR; Lazzarini, V; Parrini, D; Perini, D	1
De Zegher, F; Del Río, L; Díaz, M; Enríquez, G; Ibáñez, L; López-Bermejo, A	1
Bilgir, O; Bozkaya, G; Kebapcilar, AG; Kebapcilar, L; Sari, I; Taner, CE; Yildiz, Y	1
de Zegher, F; Díaz, M; Ibáñez, L; López-Bermejo, A	1
Decavalas, G; Diamanti-Kandarakis, E; Georgopoulos, NA; Katsikis, I; Panidis, D; Piouka, A; Saltamavros, AD	1
Adawadkar, SS; Arrowood, JA; Cheang, KI; Essah, PA; Nestler, JE; Stovall, DW	1
de Zegher, F; Diaz, M; Ibáñez, L; Lopez-Bermejo, A; Salvador, C; Sánchez-Infantes, D; Sebastiani, G	1
Gui, SQ; Kuek, S; Wang, WJ	1
Pepene, CE	1
Bayraktar, M; Cinar, N; Harmanci, A; Yildiz, BO	1
Akpek, M; Calapkorur, B; Celik, A; Karaca, Z; Kaya, MG; Kelestimur, F; Unluhizarci, K; Yildirim, S	1
Chacón, MR; de Zegher, F; Díaz, M; Ibáñez, L; López-Bermejo, A; Maymó-Masip, E; Salvador, C; Vendrell, J	1
DiVasta, AD; Veilleux-Lemieux, M	1
Cakiroglu, Y; Isgoren, S; Vural, B	1
Apa, R; Ciardulli, A; Cosentino, N; Crea, F; Familiari, A; Lanzone, A; Liuzzo, G; Martinez, D; Morciano, A; Moro, F; Niccoli, G; Palla, C; Sagnella, F; Scarinci, E; Tritarelli, A; Tropea, A	1
Altinok, ML; Andersen, M; Glintborg, D; Hermann, AP; Mumm, H; Ravn, P	1
Armutcu, F; Carlioglu, A; Gumus, II; Karakurt, F; Kasapoglu, B; Kaygusuz, I; Keskin, EA; Koca, C; Uysal, A; Uysal, S	1
Altinok, ML; Andersen, M; Bruun, JM; Glintborg, D; Mumm, H; Richelsen, B	1
Aksoy, A; Carlioglu, A; Gozukara, I; Kabil Kucur, S; Kamalak, Z; Keskin, H; Uludag, EU	1
Akpek, M; Calapkorur, B; Kaya, MG; Kelestimur, F; Unluhizarci, K; Yildirim, S	1
Cahill, DJ; O'Brien, K	1
Carter, B; Fedorowicz, Z; Pandis, N; van Zuuren, EJ	1
Jin, J; Mueck, AO; Ruan, X; Wu, H	1
Chen, A; Du, J; Du, Y; Liao, YC; Lin, XF; Wang, Y; Wu, C; Wu, RR; Ye, Y; Zhang, XB	1
Altinok, ML; Andersen, M; Glintborg, D; Mumm, H; Sidelmann, JJ	1
Sun, X; Wu, X; Yu, X; Zhang, W; Zhou, Y	1
Feng, W; Jia, YY; Shi, HR; Zhang, DY	1
de Zegher, F; Díaz, M; Gallego-Escuredo, JM; Ibáñez, L; Villarroya, F	1
Akahori, M; Dahlke, M; Gan, L; Jiang, X; Langenickel, T; Mendonza, A; Neelakantham, S; Nguyen, J; Pal, P; Rajman, I; Rebello, S; Reynolds, C; Sunkara, G; Swan, T; Zhou, W	1
Cui, N; Feng, X; Hao, G; Wang, L; Xu, Y; Zhang, J; Zhao, Z	1
de Zegher, F; Del Río, L; Díaz, M; Ibáñez, L; López-Bermejo, A; Pozo, ÓJ; Sebastiani, G	1
Andersen, M; Christensen, MMH; Glintborg, D; Pedersen, AJT; Stage, TB	1
Gu, M; Mueck, AO; Ruan, X; Song, J; Wang, H; Wang, L	2
Bodur, S; Dundar, O; Kanat-Pektas, M; Kinci, MF; Tutuncu, L	1
Mohanty, J; Nagy, A; Sahu, A; Tripathy, P	1
Shi, Y; Tang, L; Ye, J; Zhu, X	1
Krysiak, R; Okopień, B; Szkróbka, W	1
Amin, S; Bhat, IA; Fatima, Q; Ganie, MA; Jeelani, H; Kawa, IA; Manzoor, S; Rashid, F; Shah, ZA; Yousuf, SD	1
Cereijo, R; de Zegher, F; García-Beltran, C; Ibáñez, L; López-Bermejo, A; Malpique, R; Quesada-López, T; Villarroya, F	1
Huo, P; Jiang, Z; Le, J; Lei, X; Tang, Q; Tu, H; Yao, J; Zhang, R; Zhang, S	1
Artini, PG; Battaglia, B; Battaglia, C; Casadio, P; Rizzo, R	1
Hu, H; Li, F; Li, W; Liu, J; Ma, Z; Zou, G	1
Cermanova, J; Faistova, H; Faradonbeh, FA; Hroch, M; Lastuvkova, H; Micuda, S; Mokry, J; Nachtigal, P; Nova, Z; Pavek, P; Sa, II; Uher, M	1
Chen, X; Feng, Y; Li, X; Liu, Y; Wang, Y; Yao, D; Zhang, F	1

Reviews

5 review(s) available for metformin and ethinyl estradiol

Article	Year
Medical treatment regimens of hirsutism. Reproductive biomedicine online, 2004, Volume: 8, Issue:5 Topics: Androgen Antagonists; Cyproterone Acetate; Drug Combinations; Enzyme Inhibitors; Ethinyl Estradiol; Female; Finasteride; Flutamide; Hirsutism; Humans; Hypoglycemic Agents; Metformin; Mineralocorticoid Receptor Antagonists; Spironolactone	2004
Polycystic ovary syndrome. Clinical evidence, 2004, Issue:12 Topics: Androgen Antagonists; Cyproterone Acetate; Drug Therapy, Combination; Ethinyl Estradiol; Female; Finasteride; Flutamide; Hirsutism; Humans; Metformin; Polycystic Ovary Syndrome; Spironolactone	2004
Polycystic ovary syndrome. Clinical evidence, 2005, Issue:14 Topics: Cyproterone Acetate; Drug Therapy, Combination; Ethinyl Estradiol; Female; Finasteride; Flutamide; Humans; Metformin; Polycystic Ovary Syndrome; Spironolactone	2005
The effects of Diane-35 and metformin in treatment of polycystic ovary syndrome: an updated systematic review. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2008, Volume: 24, Issue:10 Topics: Algorithms; Androgen Antagonists; Cyproterone Acetate; Drug Combinations; Ethinyl Estradiol; Female; Humans; Hypoglycemic Agents; Metformin; Polycystic Ovary Syndrome; Treatment Outcome	2008
Interventions for hirsutism (excluding laser and photoepilation therapy alone). The Cochrane database of systematic reviews, 2015, Apr-28, Issue:4 Topics: 5-alpha Reductase Inhibitors; Adult; Androgen Antagonists; Body Mass Index; Contraceptive Agents, Female; Cyproterone Acetate; Desogestrel; Drug Combinations; Eflornithine; Ethinyl Estradiol; Female; Finasteride; Flutamide; Hirsutism; Humans; Hypoglycemic Agents; Metformin; Quality of Life; Randomized Controlled Trials as Topic; Spironolactone	2015

Trials

46 trial(s) available for metformin and ethinyl estradiol

Article	Year
Endocrine and metabolic effects of metformin versus ethinyl estradiol-cyproterone acetate in obese women with polycystic ovary syndrome: a randomized study. The Journal of clinical endocrinology and metabolism, 2000, Volume: 85, Issue:9 Topics: Adult; Androgen Antagonists; Area Under Curve; Blood Glucose; Calorimetry; Cyproterone Acetate; Estradiol Congeners; Ethinyl Estradiol; Fats; Female; Glucose Clamp Technique; Glucose Tolerance Test; Hormones; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Metformin; Obesity; Polycystic Ovary Syndrome	2000
Clinical, endocrine and metabolic effects of metformin added to ethinyl estradiol-cyproterone acetate in non-obese women with polycystic ovarian syndrome: a randomized controlled study. Human reproduction (Oxford, England), 2002, Volume: 17, Issue:7 Topics: Adolescent; Adult; Androstenedione; Body Constitution; Body Mass Index; Cyproterone Acetate; Drug Therapy, Combination; Ethinyl Estradiol; Female; Humans; Insulin Resistance; Metformin; Polycystic Ovary Syndrome; Prospective Studies; Sex Hormone-Binding Globulin	2002
Metformin versus ethinyl estradiol-cyproterone acetate in the treatment of nonobese women with polycystic ovary syndrome: a randomized study. The Journal of clinical endocrinology and metabolism, 2003, Volume: 88, Issue:1 Topics: Adult; Contraceptives, Oral; Cyproterone Acetate; Drug Combinations; Energy Metabolism; Estradiol Congeners; Ethinyl Estradiol; Fatty Acids, Nonesterified; Female; Hormones; Humans; Hypoglycemic Agents; Lipid Metabolism; Lipids; Metformin; Oxidation-Reduction; Polycystic Ovary Syndrome	2003
Metformin or antiandrogen in the treatment of hirsutism in polycystic ovary syndrome. The Journal of clinical endocrinology and metabolism, 2003, Volume: 88, Issue:9 Topics: Acne Vulgaris; Androgen Antagonists; Anthropometry; Blood Glucose; Blood Pressure; Body Mass Index; Cyproterone Acetate; Estradiol Congeners; Ethinyl Estradiol; Female; Hirsutism; Hormones; Humans; Hypoglycemic Agents; Insulin Resistance; Lipids; Metformin; Polycystic Ovary Syndrome; Sebum	2003
Metformin reduces serum C-reactive protein levels in women with polycystic ovary syndrome. The Journal of clinical endocrinology and metabolism, 2003, Volume: 88, Issue:10 Topics: Adult; C-Reactive Protein; Cyproterone Acetate; Estradiol Congeners; Ethinyl Estradiol; Female; Humans; Hypoglycemic Agents; Metformin; Obesity; Polycystic Ovary Syndrome; Progesterone Congeners	2003
Ethinylestradiol-drospirenone, flutamide-metformin, or both for adolescents and women with hyperinsulinemic hyperandrogenism: opposite effects on adipocytokines and body adiposity. The Journal of clinical endocrinology and metabolism, 2004, Volume: 89, Issue:4 Topics: Adiponectin; Adipose Tissue; Adolescent; Adult; Androgen Antagonists; Androstenes; Drug Therapy, Combination; Estrogens; Ethinyl Estradiol; Female; Flutamide; Hormone Antagonists; Humans; Hyperandrogenism; Hyperinsulinism; Hypoglycemic Agents; Intercellular Signaling Peptides and Proteins; Interleukin-6; Metformin; Mineralocorticoid Receptor Antagonists; Polycystic Ovary Syndrome; Proteins	2004
Flutamide-metformin plus an oral contraceptive (OC) for young women with polycystic ovary syndrome: switch from third- to fourth-generation OC reduces body adiposity. Human reproduction (Oxford, England), 2004, Volume: 19, Issue:8 Topics: Abdomen; Adipose Tissue; Adolescent; Adult; Androgen Antagonists; Contraceptives, Oral; Drug Therapy, Combination; Estrogens; Ethinyl Estradiol; Female; Flutamide; Humans; Hypoglycemic Agents; Metformin; Norpregnenes; Obesity; Polycystic Ovary Syndrome	2004
[Combined use of metformin and Diane35 in polycystic ovary syndrome]. Akusherstvo i ginekologiia, 2004, Volume: 43, Issue:3 Topics: Administration, Oral; Adolescent; Adult; Androgen Antagonists; Cyproterone Acetate; Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; Ethinyl Estradiol; Female; Humans; Metformin; Polycystic Ovary Syndrome; Prospective Studies; Treatment Outcome	2004
Flutamide-metformin plus ethinylestradiol-drospirenone for lipolysis and antiatherogenesis in young women with ovarian hyperandrogenism: the key role of early, low-dose flutamide. The Journal of clinical endocrinology and metabolism, 2004, Volume: 89, Issue:9 Topics: Adiponectin; Adolescent; Androstenes; Arteriosclerosis; Drug Therapy, Combination; Ethinyl Estradiol; Female; Flutamide; Humans; Hyperandrogenism; Intercellular Signaling Peptides and Proteins; Interleukin-6; Lipolysis; Metformin; Polycystic Ovary Syndrome; Proteins	2004
Flutamide-metformin plus ethinylestradiol-drospirenone for lipolysis and antiatherogenesis in young women with ovarian hyperandrogenism: the key role of metformin at the start and after more than one year of therapy. The Journal of clinical endocrinology and metabolism, 2005, Volume: 90, Issue:1 Topics: Adolescent; Adult; Androstenes; Arteriosclerosis; Drug Therapy, Combination; Ethinyl Estradiol; Female; Flutamide; Humans; Hyperandrogenism; Lipolysis; Metformin; Polycystic Ovary Syndrome; Time Factors	2005
Combined use of metformin and ethinyl estradiol-cyproterone acetate in polycystic ovary syndrome. European journal of obstetrics, gynecology, and reproductive biology, 2005, Feb-01, Volume: 118, Issue:2 Topics: Adult; Androgen Antagonists; Body Mass Index; Cyproterone Acetate; Dehydroepiandrosterone Sulfate; Drug Combinations; Drug Therapy, Combination; Ethinyl Estradiol; Female; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Metformin; Polycystic Ovary Syndrome; Prospective Studies; Sex Hormone-Binding Globulin; Testosterone; Waist-Hip Ratio	2005
Effects of metformin and ethinyl estradiol-cyproterone acetate on lipid levels in obese and non-obese women with polycystic ovary syndrome. European journal of endocrinology, 2005, Volume: 152, Issue:2 Topics: Adult; Androgen Antagonists; Cardiovascular Diseases; Cholesterol; Cyproterone Acetate; Ethinyl Estradiol; Female; Humans; Hypoglycemic Agents; Metformin; Obesity; Polycystic Ovary Syndrome; Treatment Outcome	2005
Comparison of ethinyl-estradiol plus cyproterone acetate versus metformin effects on classic metabolic cardiovascular risk factors in women with the polycystic ovary syndrome. The Journal of clinical endocrinology and metabolism, 2007, Volume: 92, Issue:7 Topics: Administration, Oral; Adult; Androgen Antagonists; Androgens; Blood Glucose; Cardiovascular Diseases; Cyproterone Acetate; Drug Combinations; Dyslipidemias; Ethinyl Estradiol; Female; Humans; Hypoglycemic Agents; Insulin Resistance; Lipids; Metformin; Polycystic Ovary Syndrome; Risk Factors	2007
Increased body iron stores of obese women with polycystic ovary syndrome are a consequence of insulin resistance and hyperinsulinism and are not a result of reduced menstrual losses. Diabetes care, 2007, Volume: 30, Issue:9 Topics: Adolescent; Adult; Androgen Antagonists; Cyproterone Acetate; Drug Combinations; Ethinyl Estradiol; Female; Ferritins; Humans; Hyperinsulinism; Hypoglycemic Agents; Insulin Resistance; Iron; Metformin; Obesity; Oligomenorrhea; Polycystic Ovary Syndrome	2007
Serum uric acid concentration as non-classic cardiovascular risk factor in women with polycystic ovary syndrome: effect of treatment with ethinyl-estradiol plus cyproterone acetate versus metformin. Human reproduction (Oxford, England), 2008, Volume: 23, Issue:7 Topics: Adolescent; Adult; Body Mass Index; Cross-Sectional Studies; Cyproterone Acetate; Drug Combinations; Ethinyl Estradiol; Female; Humans; Metformin; Obesity; Polycystic Ovary Syndrome; Risk Factors; Uric Acid	2008
Retinol-binding protein 4 and insulin resistance in polycystic ovary syndrome. Diabetes care, 2008, Volume: 31, Issue:7 Topics: Adult; Body Mass Index; Contraceptives, Oral; Cyproterone; Ethinyl Estradiol; Female; Glucose Tolerance Test; Humans; Hypoglycemic Agents; Insulin Resistance; Metformin; Overweight; Polycystic Ovary Syndrome; Retinol-Binding Proteins, Plasma; Waist-Hip Ratio	2008
Effects of metformin versus ethinyl-estradiol plus cyproterone acetate on ambulatory blood pressure monitoring and carotid intima media thickness in women with the polycystic ovary syndrome. Fertility and sterility, 2009, Volume: 91, Issue:6 Topics: Adult; Androgen Antagonists; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Carotid Arteries; Cyproterone Acetate; Estrogens; Ethinyl Estradiol; Female; Humans; Hypertension; Hypoglycemic Agents; Metformin; Polycystic Ovary Syndrome; Tunica Intima; Young Adult	2009
Effects of metformin and ethinyl estradiol-cyproterone acetate on clinical, endocrine and metabolic factors in women with polycystic ovary syndrome. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2008, Volume: 24, Issue:7 Topics: Adult; Contraceptives, Oral, Combined; Cyproterone Acetate; Drug Therapy, Combination; Ethinyl Estradiol; Fasting; Female; Follicle Stimulating Hormone; Humans; Hyperandrogenism; Insulin; Luteinizing Hormone; Metformin; Obesity; Polycystic Ovary Syndrome; Prospective Studies; Testosterone; Waist-Hip Ratio	2008
Endothelial function and insulin resistance in polycystic ovary syndrome: the effects of medical therapy. Fertility and sterility, 2010, Volume: 93, Issue:1 Topics: Adult; Arginine; Biomarkers; Blood Glucose; C-Reactive Protein; Contraceptives, Oral, Combined; Contraceptives, Oral, Hormonal; Cyproterone Acetate; Drug Therapy, Combination; Endothelium, Vascular; Ethinyl Estradiol; Female; Humans; Hyperandrogenism; Hypoglycemic Agents; Inflammation Mediators; Insulin; Insulin Resistance; Lipids; Metformin; Plasminogen Activator Inhibitor 1; Polycystic Ovary Syndrome; Sex Hormone-Binding Globulin; Testosterone; Time Factors; Treatment Outcome; Vasodilation; von Willebrand Factor	2010
Effects of an antiandrogenic oral contraceptive pill compared with metformin on blood coagulation tests and endothelial function in women with the polycystic ovary syndrome: influence of obesity and smoking. European journal of endocrinology, 2009, Volume: 160, Issue:3 Topics: Adult; Androgen Antagonists; Blood Coagulation; Blood Platelets; Case-Control Studies; Contraceptives, Oral, Hormonal; Cyproterone Acetate; Drug Combinations; Endothelium, Vascular; Ethinyl Estradiol; Female; Fibrinogen; Homocysteine; Humans; Hypoglycemic Agents; Metformin; Obesity; Partial Thromboplastin Time; Polycystic Ovary Syndrome; Prothrombin; Smoking; Young Adult	2009
Comparison of four different treatment regimens on coagulation parameters, hormonal and metabolic changes in women with polycystic ovary syndrome. Archives of gynecology and obstetrics, 2010, Volume: 281, Issue:1 Topics: Adult; Blood Coagulation; Cyproterone Acetate; Estrogens; Ethinyl Estradiol; Female; Fibrin Fibrinogen Degradation Products; Hormones; Humans; Hypoglycemic Agents; Insulin Resistance; Lipids; Metformin; Mineralocorticoid Receptor Antagonists; Polycystic Ovary Syndrome; Spironolactone; Weight Loss; Young Adult	2010
The effect of ethinylestradiol (EE)/cyproterone acetate (CA) and EE/CA plus metformin treatment on adhesion molecules in cases with polycystic ovary syndrome (PCOS). Internal medicine (Tokyo, Japan), 2009, Volume: 48, Issue:14 Topics: Adult; Antineoplastic Agents; Cell Adhesion Molecules; Cyproterone Acetate; Drug Therapy, Combination; Estradiol; Ethinyl Estradiol; Female; Humans; Hypoglycemic Agents; Metformin; Polycystic Ovary Syndrome; Young Adult	2009
Comparison of effects of 3 mg drospirenone plus 20 μg ethinyl estradiol alone or combined with metformin or cyproterone acetate on classic metabolic cardiovascular risk factors in nonobese women with polycystic ovary syndrome. Fertility and sterility, 2010, Volume: 94, Issue:5 Topics: Administration, Oral; Adolescent; Adult; Androgens; Androstenes; Blood Pressure; Cardiovascular Diseases; Cyproterone; Dose-Response Relationship, Drug; Drug Therapy, Combination; Estrogens; Ethinyl Estradiol; Female; Glucose; Humans; Hypoglycemic Agents; Insulin; Lipids; Metformin; Mineralocorticoid Receptor Antagonists; Polycystic Ovary Syndrome; Risk Factors; Young Adult	2010
Low-dose pioglitazone, flutamide, metformin plus an estro-progestagen for non-obese young women with polycystic ovary syndrome: increasing efficacy and persistent safety over 30 months. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2010, Volume: 26, Issue:12 Topics: Adolescent; Alanine Transaminase; Androgens; Androstenes; Aspartate Aminotransferases; Blood Glucose; Body Composition; C-Reactive Protein; Cholesterol; Cross-Over Studies; Drug Therapy, Combination; Ethinyl Estradiol; Female; Flutamide; gamma-Glutamyltransferase; Humans; Hydro-Lyases; Insulin; Longitudinal Studies; Metformin; Pioglitazone; Polycystic Ovary Syndrome; Thiazolidinediones; Tunica Intima; Young Adult	2010
Metformin plus oral contraceptive may decrease plasma sCD40 ligand in women with PCOS patients. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2011, Volume: 27, Issue:2 Topics: Adult; Androgen Antagonists; Body Mass Index; CD40 Antigens; Contraceptives, Oral; Cyproterone Acetate; Dose-Response Relationship, Drug; Down-Regulation; Drug Therapy, Combination; Ethinyl Estradiol; Female; Humans; Hypoglycemic Agents; Insulin Resistance; Metformin; Polycystic Ovary Syndrome; Young Adult	2011
Divergent effects of ethinylestradiol-drospirenone and flutamide-metformin on follistatin in adolescents and women with hyperinsulinemic androgen excess. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2011, Volume: 27, Issue:3 Topics: Adolescent; Androgen Antagonists; Androstenes; Body Composition; Contraceptives, Oral, Hormonal; Ethinyl Estradiol; Female; Flutamide; Follistatin; Humans; Hyperandrogenism; Hyperinsulinism; Metformin; Young Adult	2011
The impact of oral contraceptives and metformin on anti-Müllerian hormone serum levels in women with polycystic ovary syndrome and biochemical hyperandrogenemia. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2011, Volume: 27, Issue:8 Topics: Adolescent; Adult; Androgen Antagonists; Androstenes; Anti-Mullerian Hormone; Blood Glucose; Body Mass Index; Cohort Studies; Contraceptives, Oral, Combined; Cyproterone Acetate; Drug Combinations; Ethinyl Estradiol; Female; Humans; Hyperandrogenism; Hypoglycemic Agents; Insulin Resistance; Metformin; Polycystic Ovary Syndrome; Practice Guidelines as Topic; Young Adult	2011
Effect of combined metformin and oral contraceptive therapy on metabolic factors and endothelial function in overweight and obese women with polycystic ovary syndrome. Fertility and sterility, 2011, Volume: 96, Issue:2 Topics: Analysis of Variance; Biomarkers; Blood Glucose; Contraceptives, Oral, Combined; Contraceptives, Oral, Hormonal; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Endothelium, Vascular; Ethinyl Estradiol; Female; Gonadal Steroid Hormones; Humans; Hypoglycemic Agents; Inflammation Mediators; Insulin; Insulin Resistance; Lipids; Metformin; Norgestrel; Obesity; Overweight; Placebo Effect; Polycystic Ovary Syndrome; Time Factors; Treatment Outcome; Vasodilation; Virginia	2011
Treatment of androgen excess in adolescent girls: ethinylestradiol-cyproteroneacetate versus low-dose pioglitazone-flutamide-metformin. The Journal of clinical endocrinology and metabolism, 2011, Volume: 96, Issue:11 Topics: Abdominal Fat; Adolescent; Androgen Antagonists; Body Composition; Cyproterone Acetate; Drug Combinations; Estrogens; Ethinyl Estradiol; Female; Flutamide; Humans; Hyperandrogenism; Hyperinsulinism; Hypoglycemic Agents; Metformin; Pioglitazone; Thiazolidinediones; Treatment Outcome	2011
Efficacy of Chinese patent medicine Tian Gui Capsule in patients with polycystic ovary syndrome: a randomized controlled trial. Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine, 2011, Volume: 9, Issue:9 Topics: Adolescent; Adult; Androgen Antagonists; Cyproterone Acetate; Drug Combinations; Drugs, Chinese Herbal; Ethinyl Estradiol; Female; Humans; Metformin; Phytotherapy; Polycystic Ovary Syndrome; Young Adult	2011
Ethinyl estradiol-cyproterone acetate versus low-dose pioglitazone-flutamide-metformin for adolescent girls with androgen excess: divergent effects on CD163, TWEAK receptor, ANGPTL4, and LEPTIN expression in subcutaneous adipose tissue. The Journal of clinical endocrinology and metabolism, 2012, Volume: 97, Issue:10 Topics: Abdominal Fat; Adolescent; Androgen Antagonists; Angiopoietin-Like Protein 4; Angiopoietins; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Body Composition; Cyproterone Acetate; Dose-Response Relationship, Drug; Drug Combinations; Ethinyl Estradiol; Female; Flutamide; Gene Expression; Humans; Hyperandrogenism; Hypoglycemic Agents; Leptin; Metformin; Pioglitazone; Receptors, Cell Surface; Receptors, Tumor Necrosis Factor; Subcutaneous Fat; Thiazolidinediones; TWEAK Receptor	2012
The effects of drospirenone-ethinyl estradiol and drospirenone-ethinyl estradiol + metformin on ovarian ultrasonographic markers, body fat mass index, leptin, and ghrelin. Archives of gynecology and obstetrics, 2013, Volume: 288, Issue:1 Topics: Abdominal Fat; Adiposity; Adolescent; Adult; Androstenes; Body Mass Index; Drug Therapy, Combination; Ethinyl Estradiol; Female; Ghrelin; Humans; Leptin; Metformin; Organ Size; Ovarian Follicle; Ovary; Polycystic Ovary Syndrome; Reproductive Control Agents; Ultrasonography; Young Adult	2013
Effects of drospirenone-ethinylestradiol and/or metformin on CD4(+)CD28(null) T lymphocytes frequency in women with hyperinsulinemia having polycystic ovary syndrome: a randomized clinical trial. Reproductive sciences (Thousand Oaks, Calif.), 2013, Volume: 20, Issue:12 Topics: Adolescent; Adult; Analysis of Variance; Androstenes; Cardiovascular Diseases; CD28 Antigens; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Chi-Square Distribution; Ethinyl Estradiol; Female; Humans; Hyperinsulinism; Hypoglycemic Agents; Metformin; Polycystic Ovary Syndrome; Reproductive Control Agents; Risk Factors; Rome; Time Factors; Treatment Outcome; Young Adult	2013
Body composition is improved during 12 months' treatment with metformin alone or combined with oral contraceptives compared with treatment with oral contraceptives in polycystic ovary syndrome. The Journal of clinical endocrinology and metabolism, 2014, Volume: 99, Issue:7 Topics: Adolescent; Adult; Body Composition; Contraceptives, Oral, Combined; Desogestrel; Drug Therapy, Combination; Ethinyl Estradiol; Female; Humans; Menstrual Cycle; Metformin; Polycystic Ovary Syndrome; Treatment Outcome; Young Adult	2014
Adiponectin, interleukin-6, monocyte chemoattractant protein-1, and regional fat mass during 12-month randomized treatment with metformin and/or oral contraceptives in polycystic ovary syndrome. Journal of endocrinological investigation, 2014, Volume: 37, Issue:8 Topics: Abdominal Fat; Absorptiometry, Photon; Adiponectin; Adiposity; Adolescent; Adult; Body Mass Index; Chemokine CCL2; Contraceptives, Oral, Combined; Desogestrel; Ethinyl Estradiol; Female; Humans; Hypoglycemic Agents; Interleukin-6; Metformin; Obesity, Abdominal; Patient Dropouts; Polycystic Ovary Syndrome; Weight Gain; Whole Body Imaging; Young Adult	2014
Metformin improves endothelial function and carotid intima media thickness in patients with PCOS. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2015, Volume: 31, Issue:5 Topics: Adolescent; Adult; Androstenes; Brachial Artery; Carotid Arteries; Carotid Intima-Media Thickness; Contraceptives, Oral, Combined; Drug Therapy, Combination; Ethinyl Estradiol; Female; Humans; Hypoglycemic Agents; Metformin; Polycystic Ovary Syndrome; Treatment Outcome; Vasodilation; Young Adult	2015
Increased thrombin generation in women with polycystic ovary syndrome: A pilot study on the effect of metformin and oral contraceptives. Metabolism: clinical and experimental, 2015, Volume: 64, Issue:10 Topics: Adolescent; Adult; C-Reactive Protein; Contraceptives, Oral; Desogestrel; Ethinyl Estradiol; Female; Humans; Metformin; Pilot Projects; Polycystic Ovary Syndrome; Thrombin; Up-Regulation; Young Adult	2015
Effects of ethinylestradiol-cyproterone acetate vs. pioglitazone-flutamide-metformin on plasma FGF21 levels in adolescent girls with androgen excess. Diabetes & metabolism, 2016, Volume: 42, Issue:3 Topics: Adolescent; Cyproterone Acetate; Drug Combinations; Ethinyl Estradiol; Female; Fibroblast Growth Factors; Flutamide; Hirsutism; Humans; Hyperandrogenism; Hyperinsulinism; Longitudinal Studies; Metformin; Pioglitazone; Thiazolidinediones	2016
Pharmacokinetic drug-drug interaction assessment of LCZ696 (an angiotensin receptor neprilysin inhibitor) with omeprazole, metformin or levonorgestrel-ethinyl estradiol in healthy subjects. Clinical pharmacology in drug development, 2016, Volume: 5, Issue:1 Topics: Adolescent; Adult; Aminobutyrates; Angiotensin Receptor Antagonists; Area Under Curve; Biphenyl Compounds; Drug Combinations; Drug Interactions; Ethinyl Estradiol; Female; Humans; Levonorgestrel; Male; Metformin; Middle Aged; Omeprazole; Tetrazoles; Valsartan; Young Adult	2016
Normalizing Ovulation Rate by Preferential Reduction of Hepato-Visceral Fat in Adolescent Girls With Polycystic Ovary Syndrome. The Journal of adolescent health : official publication of the Society for Adolescent Medicine, 2017, Volume: 61, Issue:4 Topics: Adolescent; Body Mass Index; Contraceptives, Oral, Combined; Drug Combinations; Ethinyl Estradiol; Female; Hirsutism; Humans; Hypoglycemic Agents; Infertility, Female; Intra-Abdominal Fat; Levonorgestrel; Metformin; Oligomenorrhea; Ovulation; Pioglitazone; Polycystic Ovary Syndrome; Spironolactone; Thiazolidinediones	2017
The Pharmacogenetics of Metformin in Women with Polycystic Ovary Syndrome: A Randomized Trial. Basic & clinical pharmacology & toxicology, 2018, Volume: 122, Issue:2 Topics: Adult; Ataxia Telangiectasia Mutated Proteins; Biomarkers; Blood Glucose; Contraceptives, Oral, Hormonal; Desogestrel; Drug Therapy, Combination; Ethinyl Estradiol; Female; Hepatocyte Nuclear Factor 1-alpha; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Metformin; Organic Anion Transport Protein 1; Organic Cation Transport Proteins; Pharmacogenetics; Pharmacogenomic Variants; Polycystic Ovary Syndrome; Time Factors; Treatment Outcome; Triglycerides; Weight Loss; Young Adult	2018
Effect of Diane-35, alone or in combination with orlistat or metformin in Chinese polycystic ovary syndrome patients. Archives of gynecology and obstetrics, 2018, Volume: 297, Issue:6 Topics: Adipose Tissue; Adult; Androgen Antagonists; Androgens; Cyproterone Acetate; Drug Combinations; Ethinyl Estradiol; Female; Humans; Insulin Resistance; Metformin; Obesity; Orlistat; Overweight; Polycystic Ovary Syndrome; Treatment Outcome	2018
The effects of different therapeutic modalities on cardiovascular risk factors in women with polycystıc ovary syndrome: A randomızed controlled study. Taiwanese journal of obstetrics & gynecology, 2018, Volume: 57, Issue:3 Topics: Adult; Androstenes; Apolipoproteins B; Blood Glucose; C-Reactive Protein; Cardiovascular Diseases; Drug Therapy, Combination; Ethinyl Estradiol; Female; Homocysteine; Humans; Hypoglycemic Agents; Insulin Resistance; Metabolic Syndrome; Metformin; Mineralocorticoid Receptor Antagonists; Peptide Fragments; Plasminogen Activator Inhibitor 1; Polycystic Ovary Syndrome; Reproductive Control Agents; Risk Factors; Young Adult	2018
Doppler analysis of ovarian stromal blood flow changes after treatment with metformin versus ethinyl estradiol-cyproterone acetate in women with polycystic ovarian syndrome: A randomized controlled trial. Journal of gynecology obstetrics and human reproduction, 2019, Volume: 48, Issue:5 Topics: Adult; Androgen Antagonists; Androgens; Body Mass Index; Contraceptives, Oral, Combined; Cyproterone Acetate; Drug Combinations; Ethinyl Estradiol; Female; Humans; Insulin; Insulin Resistance; Luteinizing Hormone; Metformin; Ovary; Polycystic Ovary Syndrome; Prospective Studies; Regional Blood Flow; Testosterone; Ultrasonography, Doppler, Color; Waist Circumference	2019
Reduced circulating levels of chemokine CXCL14 in adolescent girls with polycystic ovary syndrome: normalization after insulin sensitization. BMJ open diabetes research & care, 2020, Volume: 8, Issue:1 Topics: Adipocytes; Adipogenesis; Adipose Tissue, Brown; Adolescent; Arrhythmias, Cardiac; Biomarkers; Chemokines, CXC; Contraceptives, Oral, Hormonal; Drug Therapy, Combination; Ethinyl Estradiol; Female; Gene Expression; Genetic Diseases, X-Linked; Gigantism; Heart Defects, Congenital; Humans; Hypoglycemic Agents; Insulin Resistance; Intellectual Disability; Levonorgestrel; Metformin; Mineralocorticoid Receptor Antagonists; Pioglitazone; Polycystic Ovary Syndrome; Spironolactone; Treatment Outcome	2020
Therapeutic effects of puerarin on polycystic ovary syndrome: A randomized trial in Chinese women. Medicine, 2021, May-28, Volume: 100, Issue:21 Topics: Administration, Oral; Adolescent; Adult; China; Cholesterol; Cyproterone Acetate; Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; Ethinyl Estradiol; Female; Humans; Isoflavones; Metformin; Obesity; Polycystic Ovary Syndrome; Primary Ovarian Insufficiency; Sex Hormone-Binding Globulin; Superoxide Dismutase; Tablets; Testosterone; Treatment Outcome; Young Adult	2021

Other Studies

34 other study(ies) available for metformin and ethinyl estradiol

Article	Year
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Neural computational prediction of oral drug absorption based on CODES 2D descriptors. European journal of medicinal chemistry, 2010, Volume: 45, Issue:3 Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
Predicting phospholipidosis using machine learning. Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5 Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
Discovery of potent, selective multidrug and toxin extrusion transporter 1 (MATE1, SLC47A1) inhibitors through prescription drug profiling and computational modeling. Journal of medicinal chemistry, 2013, Feb-14, Volume: 56, Issue:3 Topics: Computer Simulation; Fluorescent Dyes; Organic Cation Transport Proteins; Prescription Drugs	2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
[Effect of 6-month treatment with oral antiandrogen alone and in combination with insulin sensitizers on body composition, hormonal and metabolic parameters in women with polycystic ovary syndrome (PCOS) in order to determine therapeutic strategy]. Akusherstvo i ginekologiia, 2006, Volume: 45, Issue:7 Topics: Androgen Antagonists; Blood Glucose; Body Composition; Cyproterone Acetate; Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; Ethinyl Estradiol; Female; Humans; Hypoglycemic Agents; Insulin; Lipids; Metformin; Polycystic Ovary Syndrome; Rosiglitazone; Thiazolidinediones; Time Factors; Treatment Outcome	2006
Metformin and oral contraceptive treatments reduced circulating asymmetric dimethylarginine (ADMA) levels in patients with polycystic ovary syndrome (PCOS). Atherosclerosis, 2008, Volume: 200, Issue:2 Topics: Adult; Androgens; Arginine; Body Mass Index; Case-Control Studies; Contraceptives, Oral; Cyproterone Acetate; Ethinyl Estradiol; Female; Gonadotropins; Humans; Insulin Resistance; Metformin; Polycystic Ovary Syndrome; Time Factors	2008
Homeostasis model assessment-insulin resistance (HOMA-IR), a key role for assessing the ovulation function in polycystic ovary syndrome (PCOS) patients with insulin resistance. Endocrine journal, 2008, Volume: 55, Issue:5 Topics: Cyproterone Acetate; Drug Combinations; Ethinyl Estradiol; Female; Homeostasis; Humans; Hypoglycemic Agents; Insulin Resistance; Metformin; Models, Biological; Ovarian Follicle; Ovary; Ovulation; Polycystic Ovary Syndrome; Sensitivity and Specificity	2008
Reduced antidiabetic effect of metformin and down-regulation of hepatic Oct1 in rats with ethynylestradiol-induced cholestasis. Pharmaceutical research, 2009, Volume: 26, Issue:3 Topics: Animals; Blood Proteins; Blotting, Western; Catecholamine Plasma Membrane Transport Proteins; Cholestasis; Chromatography, High Pressure Liquid; Down-Regulation; Ethinyl Estradiol; Glucose; Glucose Tolerance Test; Hepatocytes; Hypoglycemic Agents; Injections, Intravenous; Liver; Male; Metabolic Clearance Rate; Metformin; Protein Binding; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Substrate Specificity; Tissue Distribution	2009
Soluble platelet/endothelial cell adhesion molecule (sPECAM)-1 is increased in polycystic ovary syndrome and related to endothelial dysfunction. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2012, Volume: 28, Issue:5 Topics: Androstenes; Case-Control Studies; Endothelium, Vascular; Ethinyl Estradiol; Female; Humans; Hypoglycemic Agents; Metformin; Platelet Endothelial Cell Adhesion Molecule-1; Polycystic Ovary Syndrome; Regression Analysis; Reproductive Control Agents; Vasodilation; Young Adult	2012
Ethinyl estradiol-drospirenone vs ethinyl estradiol-drospirenone plus metformin in the treatment of lean women with polycystic ovary syndrome. Clinical endocrinology, 2013, Volume: 78, Issue:3 Topics: Androstenes; Ethinyl Estradiol; Female; Humans; Male; Metformin; Middle Aged; Polycystic Ovary Syndrome; Thinness	2013
The effects of treatment with drospirenone/ethinyl oestradiol alone or in combination with metformin on elastic properties of aorta in women with polycystic ovary syndrome. Clinical endocrinology, 2012, Volume: 77, Issue:6 Topics: Adolescent; Adult; Androstenes; Aorta; Body Mass Index; Drug Therapy, Combination; Ethinyl Estradiol; Female; Humans; Hypoglycemic Agents; Metformin; Polycystic Ovary Syndrome; Treatment Outcome; Vascular Stiffness; Weight Loss	2012
Severe hyperandrogenemia and insulin resistance in a 12-year-old girl. Journal of pediatric and adolescent gynecology, 2012, Volume: 25, Issue:4 Topics: Child; Estrogens; Ethinyl Estradiol; Female; Humans; Hyperandrogenism; Hyperinsulinism; Hypoglycemic Agents; Insulin Resistance; Metformin; Polycystic Ovary Syndrome; Testosterone	2012
The platelet activating factor acetyl hydrolase, oxidized low-density lipoprotein, paraoxonase 1 and arylesterase levels in treated and untreated patients with polycystic ovary syndrome. Archives of gynecology and obstetrics, 2014, Volume: 290, Issue:5 Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Adult; Androgen Antagonists; Aryldialkylphosphatase; Body Mass Index; Carboxylic Ester Hydrolases; Case-Control Studies; Cyproterone Acetate; Drug Combinations; Ethinyl Estradiol; Female; Humans; Hypoglycemic Agents; Lipoproteins, LDL; Metformin; Phospholipase A2 Inhibitors; Platelet Activating Factor; Polycystic Ovary Syndrome; Polymorphism, Single Nucleotide; Treatment Outcome	2014
How medical treatment affects mean platelet volume as a cardiovascular risk marker in polycystic ovary syndrome? Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2015, Volume: 26, Issue:8 Topics: Adolescent; Adult; Androgen Antagonists; Biomarkers; Blood Platelets; Body Mass Index; C-Reactive Protein; Cardiovascular Diseases; Case-Control Studies; Cyproterone Acetate; Drug Combinations; Ethinyl Estradiol; Female; Humans; Hypoglycemic Agents; Insulin Resistance; Leukocyte Count; Mean Platelet Volume; Metformin; Polycystic Ovary Syndrome; Regression Analysis; Treatment Outcome	2015
Polycystic ovary syndrome (PCOS): metformin. BMJ clinical evidence, 2015, Mar-27, Volume: 2015 Topics: Androgen Antagonists; Cyproterone Acetate; Drug Combinations; Ethinyl Estradiol; Female; Humans; Hypoglycemic Agents; Metformin; Polycystic Ovary Syndrome; Weight Reduction Programs	2015
Metabolic profile of Diane-35 versus Diane-35 plus metformin in Chinese PCOS women under standardized life-style changes. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2015, Volume: 31, Issue:7 Topics: Adolescent; Adult; Androgen Antagonists; China; Cyproterone Acetate; Drug Combinations; Drug Therapy, Combination; Ethinyl Estradiol; Female; Humans; Hyperandrogenism; Hypoglycemic Agents; Metabolome; Metformin; Polycystic Ovary Syndrome; Treatment Outcome; Young Adult	2015
Exploring the significance of sex hormone-binding globulin examination in the treament of women with polycystic ovarian syndrome (PCOS). Clinical and experimental obstetrics & gynecology, 2015, Volume: 42, Issue:3 Topics: Abortion, Spontaneous; Adult; Androgen Antagonists; Blood Glucose; Body Mass Index; Clomiphene; Cyproterone Acetate; Drug Combinations; Drug Therapy, Combination; Estradiol; Ethinyl Estradiol; Female; Fertility Agents, Female; Follicle Stimulating Hormone; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Live Birth; Luteinizing Hormone; Metformin; Obesity; Ovulation Induction; Polycystic Ovary Syndrome; Prolactin; Sex Hormone-Binding Globulin; Testosterone; Treatment Outcome; Young Adult	2015
Evaluation of Apelin and Insulin Resistance in Patients with PCOS and Therapeutic Effect of Drospirenone-Ethinylestradiol Plus Metformin. Medical science monitor : international medical journal of experimental and clinical research, 2015, Aug-28, Volume: 21 Topics: Adult; Androstenes; Apelin; Blood Glucose; Body Mass Index; Case-Control Studies; Drug Therapy, Combination; Ethinyl Estradiol; Female; Gonadal Steroid Hormones; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Intercellular Signaling Peptides and Proteins; Metformin; Polycystic Ovary Syndrome; Reproductive Control Agents; Young Adult	2015
Management of polycystic ovarian syndrome with Diane-35 or Diane-35 plus metformin. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2016, Volume: 32, Issue:2 Topics: Adult; Androgen Antagonists; Cyproterone Acetate; Drug Combinations; Ethinyl Estradiol; Female; Humans; Hypoglycemic Agents; Metformin; Outcome Assessment, Health Care; Polycystic Ovary Syndrome; Young Adult	2016
Restored Plasma Anandamide and Endometrial Expression of Fatty Acid Amide Hydrolase in Women With Polycystic Ovary Syndrome by the Combination Use of Diane-35 and Metformin. Clinical therapeutics, 2017, Volume: 39, Issue:4 Topics: Adult; Amidohydrolases; Androgen Antagonists; Arachidonic Acids; Cyproterone Acetate; Drug Combinations; Endocannabinoids; Endometrium; Ethinyl Estradiol; Female; Glycerides; Humans; Infertility, Female; Metformin; Polycystic Ovary Syndrome; Polyunsaturated Alkamides; Receptors, Cannabinoid; Young Adult	2017
Effect of orlistat or metformin in overweight and obese polycystic ovary syndrome patients with insulin resistance. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2018, Volume: 34, Issue:5 Topics: Adult; Anti-Obesity Agents; Cyproterone Acetate; Drug Combinations; Drug Therapy, Combination; Ethinyl Estradiol; Female; Humans; Hypoglycemic Agents; Insulin Resistance; Lactones; Metformin; Obesity; Orlistat; Overweight; Polycystic Ovary Syndrome; Young Adult	2018
Association between CD16 International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2019, Volume: 145, Issue:1 Topics: Adult; Biomarkers; Case-Control Studies; China; Cross-Sectional Studies; Cyproterone Acetate; Drug Combinations; Drug Therapy, Combination; Ethinyl Estradiol; Female; Humans; Hyperandrogenism; Insulin Resistance; Metformin; Monocytes; Polycystic Ovary Syndrome; Prospective Studies; Receptors, IgG	2019
The Impact of Ethinyl Estradiol on Metformin Action on Prolactin Levels in Women with Hyperprolactinemia. Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2021, Volume: 129, Issue:1 Topics: Adult; Blood Glucose; Case-Control Studies; Contraceptives, Oral, Hormonal; Diabetes Mellitus; Ethinyl Estradiol; Female; Humans; Hyperprolactinemia; Hypoglycemic Agents; Lactotrophs; Luteinizing Hormone; Metformin; Prediabetic State; Prolactin; Young Adult	2021
Oral contraceptive use increases risk of inflammatory and coagulatory disorders in women with Polycystic Ovarian Syndrome: An observational study. Scientific reports, 2019, 07-15, Volume: 9, Issue:1 Topics: Adult; Body Mass Index; Coagulation Protein Disorders; Contraceptives, Oral; Ethinyl Estradiol; Female; Humans; India; Inflammation; Insulin; Insulin Resistance; Levonorgestrel; Metformin; Polycystic Ovary Syndrome; Risk Factors; Waist-Hip Ratio; Young Adult	2019
Combined use of Diane-35 and metformin improves the ovulation in the PCOS rat model possibly via regulating glycolysis pathway. Reproductive biology and endocrinology : RB&E, 2020, Jun-03, Volume: 18, Issue:1 Topics: Androgen Antagonists; Animals; Apoptosis; Body Weight; Cyproterone Acetate; Disease Models, Animal; Drug Combinations; Drug Therapy, Combination; Ethinyl Estradiol; Female; Glycolysis; Hypoglycemic Agents; Insulin Resistance; Lactate Dehydrogenase 5; Luteinizing Hormone; Metformin; Ovary; Ovulation; Polycystic Ovary Syndrome; Pyruvate Kinase; Rats; Sirtuin 1; Testosterone	2020
Metformin metabolic and vascular effects in normal weight hyperinsulinemic polycystic ovary syndrome patients treated with contraceptive vaginal ring. A pilot study. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2020, Volume: 36, Issue:12 Topics: Adult; Blood Glucose; Brachial Artery; Contraceptive Agents, Hormonal; Contraceptive Devices, Female; Desogestrel; Ethinyl Estradiol; Female; Glucose Tolerance Test; Humans; Hyperinsulinism; Hypoglycemic Agents; Insulin Resistance; Longitudinal Studies; Metformin; Ophthalmic Artery; Pilot Projects; Polycystic Ovary Syndrome; Retrospective Studies; Ultrasonography, Doppler; Vasodilation; Young Adult	2020
Metformin impairs bile acid homeostasis in ethinylestradiol-induced cholestasis in mice. Chemico-biological interactions, 2021, Aug-25, Volume: 345 Topics: Animals; Bile Acids and Salts; Cholestasis; Ethinyl Estradiol; Female; Hepatocytes; Homeostasis; Intestinal Absorption; Metformin; Mice; Mice, Inbred C57BL	2021
Diane-35 and Metformin Induce Autophagy and Apoptosis in Polycystic Ovary Syndrome Women with Early-Stage Endometrial Carcinoma. Genes, 2022, 01-12, Volume: 13, Issue:1 Topics: Androgen Antagonists; Animals; Apoptosis; Autophagy; Cyproterone Acetate; Drug Combinations; Drug Therapy, Combination; Endometrial Neoplasms; Ethinyl Estradiol; Female; Glucose Transporter Type 4; Hypoglycemic Agents; Insulin-Like Growth Factor I; Metformin; Mice; Polycystic Ovary Syndrome; Receptors, Androgen	2022