metformin has been researched along with epothilone a in 2 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 2 (100.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Drzewoski, J; Kasznicki, J; Marczak, A; Rogalska, A; Sliwinska, A | 1 |
Bukowska, B; Marczak, A; Rogalska, A | 1 |
2 other study(ies) available for metformin and epothilone a
Article | Year |
---|---|
Effects of Epothilone A in Combination with the Antidiabetic Drugs Metformin and Sitagliptin in HepG2 Human Hepatocellular Cancer Cells: Role of Transcriptional Factors NF-κB and p53.
Topics: Antineoplastic Agents; Apoptosis; Benzoxazoles; Carcinoma, Hepatocellular; Dactinomycin; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Epothilones; Hep G2 Cells; Humans; Hypoglycemic Agents; Liver Neoplasms; Metformin; NF-kappa B; Sitagliptin Phosphate; Tumor Suppressor Protein p53 | 2016 |
Metformin and epothilone A treatment up regulate pro-apoptotic PARP-1, Casp-3 and H2AX genes and decrease of AKT kinase level to control cell death of human hepatocellular carcinoma and ovary adenocarcinoma cells.
Topics: Adenocarcinoma; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carcinoma, Hepatocellular; Caspase 3; Cell Line, Tumor; DNA Damage; Drug Resistance, Neoplasm; Epothilones; Female; Gene Expression Regulation, Neoplastic; Histones; Humans; Hypoglycemic Agents; Liver Neoplasms; Metformin; Neoplasm Proteins; Ovarian Neoplasms; Oxidative Stress; Poly (ADP-Ribose) Polymerase-1; Proto-Oncogene Proteins c-akt | 2018 |