metformin has been researched along with endothelin-1 in 11 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (45.45) | 29.6817 |
| 2010's | 3 (27.27) | 24.3611 |
| 2020's | 3 (27.27) | 2.80 |
| Authors | Studies |
|---|---|
| Diamanti-Kandarakis, E; Kouli, C; Migdalis, I; Spina, G | 1 |
| Evans, M; Rees, A; Roberts, AW; Thomas, A | 1 |
| Aessopos, A; Alexandraki, K; Diamanti-Kandarakis, E; Lekakis, J; Mavrikakis, M; Papamichael, C; Piperi, C; Protogerou, A | 1 |
| Azziz, R; Cascella, T; Colao, A; De Simone, B; Lombardi, G; Manguso, F; Orio, F; Palomba, S; Russo, T; Savastano, S; Tolino, A; Zullo, F | 1 |
| Dorrance, AM; Elgebaly, MM; Ergul, A; Hutchinson, JR; Mezzetti, EM; Motamed, K; Sachidanandam, K | 1 |
| Colao, A; Falbo, A; Giallauria, F; Orio, F; Palomba, S; Russo, T; Tolino, A; Zullo, F | 1 |
| Bayram, F; Diri, H; Kocer, D | 1 |
| Feng, W; Han, D; Ke, R; Li, M; Li, S; Liu, L; Wang, G; Wu, Y; Zhang, Y | 1 |
| Brownfoot, FC; Cannon, P; Cluver, C; Hannan, NJ; Hastie, R; Kaitu'u-Lino, TJ; Nguyen, TV; Tong, S; Tuohey, L | 1 |
| El Kiki, SM; Hasan, HF; Mansour, HH; Omran, MM | 1 |
| Chen, H; Gao, X; Li, J; Li, Y; Liu, J; Liu, P; Ren, Y; Song, S; Wang, B; Wang, H; Wang, R; Wang, Y; Zhang, M | 1 |
1 review(s) available for metformin and endothelin-1
| Article | Year |
|---|---|
Peroxisome proliferator-activated receptor-gamma agonists in atherosclerosis: current evidence and future directions.
Topics: Albuminuria; Arteriosclerosis; Blood Pressure; C-Reactive Protein; Carotid Arteries; Coronary Restenosis; Diabetes Mellitus, Type 2; Endothelin-1; Endothelium, Vascular; Humans; Hyperglycemia; Insulin Resistance; Lipoproteins; Matrix Metalloproteinases; Metformin; Muscle, Smooth, Vascular; Pioglitazone; Plasminogen Activator Inhibitor 1; PPAR gamma; Rosiglitazone; Thiazolidinediones | 2003 |
1 trial(s) available for metformin and endothelin-1
| Article | Year |
|---|---|
Metformin administration improves endothelial function in women with polycystic ovary syndrome.
Topics: Adult; Brachial Artery; Endothelin-1; Endothelium, Vascular; Female; Glucose Intolerance; Humans; Hypoglycemic Agents; Insulin Resistance; Metformin; Polycystic Ovary Syndrome; Testosterone; Vasodilation | 2005 |
9 other study(ies) available for metformin and endothelin-1
| Article | Year |
|---|---|
Increased endothelin-1 levels in women with polycystic ovary syndrome and the beneficial effect of metformin therapy.
Topics: Adolescent; Adult; Androgens; Blood Glucose; Endothelin-1; Endothelium, Vascular; Female; Humans; Hypoglycemic Agents; Insulin Resistance; Metformin; Polycystic Ovary Syndrome; Regression Analysis | 2001 |
Improvement in endothelial structure and function after metformin treatment in young normal-weight women with polycystic ovary syndrome: results of a 6-month study.
Topics: Area Under Curve; Cardiovascular Diseases; Endothelin-1; Endothelium, Vascular; Female; Humans; Hypoglycemic Agents; Insulin Resistance; Metformin; Polycystic Ovary Syndrome; Prospective Studies | 2005 |
Glycemic control prevents microvascular remodeling and increased tone in type 2 diabetes: link to endothelin-1.
Topics: Animals; Blood Glucose; Collagen; Diabetes Mellitus, Type 2; Disease Models, Animal; Endothelin-1; Hyperplasia; Hypoglycemic Agents; Male; Matrix Metalloproteinase 13; Mesenteric Arteries; Metformin; Microvessels; Rats; Rats, Wistar; Receptor, Endothelin A; Receptor, Endothelin B; Vasoconstriction | 2009 |
Effects of metformin with or without supplementation with folate on homocysteine levels and vascular endothelium of women with polycystic ovary syndrome.
Topics: Adult; Body Mass Index; Brachial Artery; Double-Blind Method; Endothelin-1; Endothelium, Vascular; Exercise; Female; Folic Acid; Homocysteine; Humans; Hypoglycemic Agents; Leisure Activities; Metformin; Placebos; Polycystic Ovary Syndrome; Tunica Intima; Tunica Media; Vasodilation; Vitamin B 12; Waist-Hip Ratio | 2010 |
The effects of metformin on endothelial dysfunction, lipid metabolism and oxidative stress in women with polycystic ovary syndrome.
Topics: Adult; Apolipoprotein A-I; Apolipoproteins B; Aryldialkylphosphatase; Case-Control Studies; Cholesterol, LDL; Endothelin-1; Estradiol; Female; Follicle Stimulating Hormone; Humans; Hypoglycemic Agents; Insulin Resistance; Lipid Metabolism; Luteinizing Hormone; Malondialdehyde; Metformin; Nitric Oxide; Oxidative Stress; Polycystic Ovary Syndrome; Progesterone; Young Adult | 2014 |
Activation of AMPK inhibits pulmonary arterial smooth muscle cells proliferation.
Topics: AMP-Activated Protein Kinases; Animals; Cell Proliferation; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p27; Endothelin-1; Enzyme Activation; Metformin; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Pulmonary Artery; Rats; Rats, Sprague-Dawley; S-Phase Kinase-Associated Proteins | 2014 |
Combining metformin and sulfasalazine additively reduces the secretion of antiangiogenic factors from the placenta: Implications for the treatment of preeclampsia.
Topics: Drug Therapy, Combination; Endoglin; Endothelin-1; Female; Humans; Metformin; Placenta; Placenta Growth Factor; Pre-Eclampsia; Pregnancy; Sulfasalazine; Vascular Cell Adhesion Molecule-1; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1 | 2020 |
Metformin and/or low dose radiation reduces cardiotoxicity and apoptosis induced by cyclophosphamide through SIRT-1/SOD and BAX/Bcl-2 pathways in rats.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Cardiotoxicity; Cyclophosphamide; Endothelin-1; Gamma Rays; Heart; Hypoglycemic Agents; Male; Metformin; Myocardium; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar; Sirtuin 1; Superoxide Dismutase; Troponin; Whole-Body Irradiation | 2020 |
Metformin and simvastatin synergistically suppress endothelin 1-induced hypoxia and angiogenesis in multiple cancer types.
Topics: Animals; Cell Line, Tumor; Endothelin-1; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Metformin; Mice; Neoplasms; Neovascularization, Pathologic; Simvastatin | 2023 |