metformin and enalapril

metformin has been researched along with enalapril in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (10.00)18.2507
2000's4 (20.00)29.6817
2010's9 (45.00)24.3611
2020's5 (25.00)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Campillo, NE; Guerra, A; Páez, JA1
Benet, LZ; Brouwer, KL; Chu, X; Dahlin, A; Evers, R; Fischer, V; Giacomini, KM; Hillgren, KM; Hoffmaster, KA; Huang, SM; Ishikawa, T; Keppler, D; Kim, RB; Lee, CA; Niemi, M; Polli, JW; Sugiyama, Y; Swaan, PW; Tweedie, DJ; Ware, JA; Wright, SH; Yee, SW; Zamek-Gliszczynski, MJ; Zhang, L1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Giacomini, KM; Huang, Y; Khuri, N; Kido, Y; Kosaka, A; Morrissey, KM; Sali, A; Wittwer, MB; Zhang, X; Zur, AA1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Elisabetta, Z; Emanuela, M; Franzetti, I; Marco, G; Paolo, D; Renato, U1
Casanova, P; Flórez, H1
Anil, SK; Dinesh, KU; Durga, B; Pranaya, M; Shankar, PR; Subish, P1
Apaijai, N; Chattipakorn, N; Chattipakorn, SC; Inthachai, T; Kumfu, S; Lekawanvijit, S; Pongkan, W1
Akabuogu, EU; Phyu, SM; Smith, TA1
Apaijai, N; Chattipakorn, N; Chattipakorn, SC; Inthachai, T; Lekawanvijit, S1
Abdellatif, AA; Barakat, MK; Elsharkawy, AM; Khedr, MM; Mostafa, DK1
Janssen, WMT; Roosma, E; van Londen, M; van Putten, JWG; Vogels, S1
Gou, XY; Ma, YR; Ran, FL; Wu, XA; Wu, YF1
Tchernev, G1
Blahova, J; Doubkova, V; Faldyna, M; Hesova, R; Hodkovicova, N; Hollerova, A; Kotoucek, J; Lakdawala, P; Mares, J; Marsalek, P; Medkova, D; Svobodova, Z; Taştan, Y; Tichy, F1

Reviews

2 review(s) available for metformin and enalapril

ArticleYear
Membrane transporters in drug development.
    Nature reviews. Drug discovery, 2010, Volume: 9, Issue:3

    Topics: Animals; Computer Simulation; Decision Trees; Drug Approval; Drug Discovery; Drug Evaluation, Preclinical; Drug Interactions; Humans; Membrane Transport Proteins; Mice; Mice, Knockout; Prescription Drugs

2010
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

18 other study(ies) available for metformin and enalapril

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Discovery of potent, selective multidrug and toxin extrusion transporter 1 (MATE1, SLC47A1) inhibitors through prescription drug profiling and computational modeling.
    Journal of medicinal chemistry, 2013, Feb-14, Volume: 56, Issue:3

    Topics: Computer Simulation; Fluorescent Dyes; Organic Cation Transport Proteins; Prescription Drugs

2013
Possible synergistic effect of metformin and enalapril on the development of hyperkaliemic lactic acidosis.
    Diabetes research and clinical practice, 1997, Volume: 38, Issue:3

    Topics: Acidosis; Aged; Antihypertensive Agents; Chlorides; Diabetes Mellitus, Type 2; Drug Synergism; Drug Therapy, Combination; Enalapril; Female; Humans; Hypertension; Hypoglycemic Agents; Lactic Acid; Metformin

1997
[Changes in clinical intervention studies: when the wellbeing of the patients takes precedence].
    Investigacion clinica, 1998, Volume: 39, Issue:3

    Topics: Antihypertensive Agents; Chromans; Clinical Trials as Topic; Diabetes Complications; Enalapril; Ethics, Medical; Hypertension; Hypoglycemic Agents; Metformin; Multicenter Studies as Topic; Nisoldipine; Prediabetic State; Prospective Studies; Thiazoles; Thiazolidinediones; Treatment Failure; Troglitazone

1998
Pattern of potential drug-drug interactions in diabetic out-patients in a tertiary care teaching hospital in Nepal.
    The Medical journal of Malaysia, 2007, Volume: 62, Issue:4

    Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Aged; Antihypertensive Agents; Child; Cross-Sectional Studies; Diabetes Mellitus; Drug Interactions; Enalapril; Female; Hospitals, Teaching; Humans; Hypoglycemic Agents; Incidence; Male; Metformin; Middle Aged; Nepal; Outpatients; Prospective Studies; Risk Factors

2007
Dipeptidyl peptidase-4 inhibitor improves cardiac function by attenuating adverse cardiac remodelling in rats with chronic myocardial infarction.
    Experimental physiology, 2015, Volume: 100, Issue:6

    Topics: Adamantane; Angiotensin-Converting Enzyme Inhibitors; Animals; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Disease Models, Animal; Enalapril; Fibrosis; Heart Rate; Hypoglycemic Agents; Male; Metformin; Myocardial Infarction; Myocardium; Nitriles; Oxidative Stress; Pyrrolidines; Rats, Wistar; Recovery of Function; Signal Transduction; Time Factors; Ventricular Dysfunction, Left; Ventricular Function, Left; Ventricular Remodeling; Vildagliptin

2015
Effects of Administered Cardioprotective Drugs on Treatment Response of Breast Cancer Cells.
    Anticancer research, 2016, Volume: 36, Issue:1

    Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carbazoles; Cardiomyopathies; Cardiotonic Agents; Cardiovascular Agents; Carvedilol; Cell Line, Tumor; Cell Survival; Dexrazoxane; Dose-Response Relationship, Drug; Doxorubicin; Drug Interactions; Enalapril; Female; Fluorodeoxyglucose F18; Humans; Metformin; Propanolamines; Radionuclide Imaging; Radiopharmaceuticals; Receptor, ErbB-2; Trastuzumab

2016
Effects of dipeptidyl peptidase-4 inhibitor in insulin-resistant rats with myocardial infarction.
    The Journal of endocrinology, 2016, Volume: 229, Issue:3

    Topics: Adamantane; Animals; Cardiotonic Agents; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Enalapril; Heart Rate; Hypoglycemic Agents; Insulin Resistance; Male; Metformin; Myocardial Infarction; Nitriles; Oxidative Stress; Pyrrolidines; Rats; Rats, Wistar; Ventricular Remodeling; Vildagliptin

2016
Autophagy blockade mechanistically links proton pump inhibitors to worsened diabetic nephropathy and aborts the renoprotection of metformin/enalapril.
    Life sciences, 2021, Jan-15, Volume: 265

    Topics: Albuminuria; Animals; Autophagy; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Diet, High-Fat; Enalapril; Lansoprazole; Male; Metformin; Mice; Oxidative Stress; Proton Pump Inhibitors; Streptozocin

2021
Acute kidney injury and long-term renal effects of alectinib in anaplastic lymphoma kinase-positive non-small cell lung carcinoma: a case report.
    Journal of medical case reports, 2022, Sep-29, Volume: 16, Issue:1

    Topics: Acute Kidney Injury; Aged; Anaplastic Lymphoma Kinase; Anti-Inflammatory Agents; Antineoplastic Agents; Carbazoles; Carcinoma, Non-Small-Cell Lung; Creatinine; Enalapril; Female; Humans; Kidney; Lung Neoplasms; Metformin; Microtubule-Associated Proteins; Naproxen; Piperidines; Protein Kinase Inhibitors; Sodium

2022
Enalapril increases the urinary excretion of metformin in rats by inducing multidrug and toxin excretion protein 1 in the kidney.
    Biopharmaceutics & drug disposition, 2022, Volume: 43, Issue:6

    Topics: Animals; Antiporters; Diabetes Mellitus, Type 2; Enalapril; Kidney; Metformin; Organic Cation Transport Proteins; Organic Cation Transporter 2; Rats; Rats, Wistar

2022
NITROSOGENESIS OF SKIN CANCER: THE NITROSAMINE CONTAMINATION IN THE CALCIUM CHANNEL BLOCKERS (AMLODIPINE), BETA BLOCKERS (BISOPROLOL), SARTANS (VALSARTAN/LOSARTAN), ACE INHIBITORS (PERINDOPRIL/ENALAPRIL), TRICYCLIC ANTIDEPRESSANTS (MELITRACEN), SSRIS (PAR
    Georgian medical news, 2023, Issue:339

    Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antidepressive Agents, Tricyclic; Bisoprolol; Calcium Channel Blockers; Enalapril; Humans; Incidence; Losartan; Metformin; Paroxetine; Perindopril; Selective Serotonin Reuptake Inhibitors; Serotonin and Noradrenaline Reuptake Inhibitors; Skin Neoplasms; Valsartan; Venlafaxine Hydrochloride

2023
Medicine designed to combat diseases of affluence affects the early development of fish. How do plastic microparticles contribute?
    The Science of the total environment, 2023, Dec-15, Volume: 904

    Topics: Animals; Carps; Enalapril; Metformin; Metoprolol; Microplastics; Pharmaceutical Preparations; Plastics; Polystyrenes; Water; Water Pollutants, Chemical; Zebrafish

2023