metformin has been researched along with disulfiram in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (7.14) | 29.6817 |
| 2010's | 10 (71.43) | 24.3611 |
| 2020's | 3 (21.43) | 2.80 |
| Authors | Studies |
|---|---|
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Birkhead, M; Damelin, LH; Jivan, R; Mavri-Damelin, D; Rousseau, AL; Veale, RB | 1 |
| Damelin, LH; Jivan, R; Mavri-Damelin, D; Peres, J; Prince, S; Veale, RB; Wadee, R | 1 |
| Čapo, I; Lalošević, D; Miljković, D; Popović, DJ; Popović, JK; Popović, KJ; Poša, M | 1 |
| Cheng, Y; Chi, Y; Dong, X; Dong, Y; He, Y; Huang, T; Jia, Y; Li, X; Shen, B; Wang, J; Wang, Z; Wu, X; Xiao, H; Yang, X; Yin, S; Zhai, L; Zhang, L; Zhao, L; Zhou, J | 1 |
| Chen, P; Huang, J; Liang, Q; Liang, X; Liu, J; Wu, T; Xiang, Y; Zeng, H; Zeng, Y; Zhou, C | 1 |
1 review(s) available for metformin and disulfiram
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
13 other study(ies) available for metformin and disulfiram
| Article | Year |
|---|---|
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics | 2011 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Disulfiram/copper-disulfiram Damages Multiple Protein Degradation and Turnover Pathways and Cytotoxicity is Enhanced by Metformin in Oesophageal Squamous Cell Carcinoma Cell Lines.
Topics: Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Copper; Disulfiram; Drug Synergism; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Humans; Metformin; Proteasome Endopeptidase Complex; Proteolysis | 2015 |
Disulfiram with or without metformin inhibits oesophageal squamous cell carcinoma in vivo.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Autophagy; Carcinoma, Squamous Cell; Cell Line, Tumor; Disulfiram; Esophageal Neoplasms; Humans; Metformin; Mice, Nude; Tumor Burden; Xenograft Model Antitumor Assays | 2018 |
Disulfiram and metformin combination anticancer effect reversible partly by antioxidant nitroglycerin and completely by NF-κB activator mebendazole in hamster fibrosarcoma.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Disulfiram; Female; Fibrosarcoma; Male; Mebendazole; Mesocricetus; Metformin; Neoplasms, Experimental; NF-kappa B; Nitroglycerin; Oxidative Stress; Signal Transduction; Tumor Burden | 2021 |
Targeting Cancer Metabolism Plasticity with JX06 Nanoparticles via Inhibiting PDK1 Combined with Metformin for Endometrial Cancer Patients with Diabetes.
Topics: Animals; Cell Line, Tumor; Cell Proliferation; Diabetes Mellitus; Disulfiram; Endometrial Neoplasms; Female; Humans; Metformin; Mice; Morpholines; Nanoparticles | 2022 |
Gut microbiota dysbiosis-derived macrophage pyroptosis causes polycystic ovary syndrome via steroidogenesis disturbance and apoptosis of granulosa cells.
Topics: Animals; Apoptosis; Dehydroepiandrosterone; Disulfiram; DNA, Ribosomal; Dysbiosis; Estrogens; Female; Gastrointestinal Microbiome; Granulosa Cells; Humans; Lipopolysaccharides; Macrophages; Metformin; Mice; Polycystic Ovary Syndrome; Pyroptosis | 2022 |