metformin has been researched along with dimethylnitrosamine in 20 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (25.00) | 24.3611 |
| 2020's | 15 (75.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Liu, CH; Tang, LR; Tao, YY; Wang, HN | 1 |
| Antonelli, M; Aquillon, CG; Breider, F; Piazzoli, A; von Gunten, U | 1 |
| Deng, X; Fan, H; Guo, L; Jiang, W; Lu, SH; Yu, X; Zhan, Q; Zheng, W; Zou, Z | 1 |
| Keire, DA; Marzan, TA; Rodriguez, JD; Sommers, CD; Yang, J; Ye, W | 1 |
| Lim, HH; Oh, YS; Shin, HS | 1 |
| Książek, I; Szterk, A; Zmysłowski, A | 1 |
| Douša, M; Gibala, P; Hrubý, J; Jireš, J; Kalášek, S; Kubelka, T; Řezanka, P; Rudovský, J | 1 |
| Ahmed, EO; ElMeshad, AN; Fares, AR; Metwaly, MG; Nasr, NEH | 2 |
| Brackhagen, M; Dreibelbis, M; Kerry, M; Lee, D; Mintert, M; Serr, B; Tocce, E; Zhu, J; Zhu, K | 1 |
| Baranowski, R; Barrau, E; Blom, G; Bristow, T; Cimelli, A; Desmartin, E; Fritzsche, M; Goettsche, A; Guessregen, B; Harrison, M; Hickert, S; Keitel, J; Kirsch, A; Krueger, P; Leicht, S; Mouton, B; O'Neill, N; Reifenberg, P; Saal, C; Schlingemann, J; Seegel, M | 1 |
| Boucley, C; Bourasseau, L; Celdran, C; Chemarin, T; Fritzsche, M; Goettsche, A; Guessregen, B; Hickert, S; Keitel, J; Kirsch, A; Krueger, P; Leicht, S; Liebhold, M; Masanes, S; Mouton, B; Müller, T; Pegues, C; Reifenberg, P; Saal, C; Schlingemann, J; Schooren, F; Schuster, T; Seegel, M; Walker, M; Wetzel, S | 1 |
| Bream, R; Burchardt, A; Conti, M; George, M; Keire, DA; Keizers, P; Morin, J; Poh, J; Schmaler-Ripcke, J; Wierer, M; Wollein, U; Zmysłowski, A | 1 |
| Ali, HI; Dharani, S; Khan, MA; Khuroo, T; Mohamed, EM; Rahman, Z; Reddy, IK | 1 |
| Chang, CC; Chang, SH; Ho, HY; Hsu, YH; Lin, MC; Tseng, SH; Wang, DY; Zang, CZ | 1 |
| Chu, D; Gao, P; Hao, G; Hu, R; Huang, F; Jiang, M; Lv, J; Song, X; Sun, F; Tan, G; Wang, L; Wang, X; Xin, L; You, J; Zhao, Y | 1 |
| Ge, X; Kee, CL; Lim, JQ; Low, MY; Teo Jessie, HG; Zeng, Y | 1 |
| Blom, G; Géhin, C; Harrison, M; Holman, SW; Moore, A; O'Neill, N | 1 |
1 review(s) available for metformin and dimethylnitrosamine
| Article | Year |
|---|---|
International Regulatory Collaboration on the Analysis of Nitrosamines in Metformin-Containing Medicines.
Topics: Dimethylnitrosamine; Humans; Metformin; Nitrosamines | 2022 |
19 other study(ies) available for metformin and dimethylnitrosamine
| Article | Year |
|---|---|
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Salvianolate Reduces Glucose Metabolism Disorders in Dimethylnitrosamine-Induced Cirrhotic Rats.
Topics: Animals; Dimethylnitrosamine; Glucose; Glucose Tolerance Test; Insulin Resistance; Liver; Liver Cirrhosis, Experimental; Liver Glycogen; Male; Metformin; Plant Extracts; Rats; Rats, Wistar | 2018 |
Specific and total N-nitrosamines formation potentials of nitrogenous micropollutants during chloramination.
Topics: Amines; Chloramines; Chlorhexidine; Dimethylnitrosamine; Drinking Water; Metformin; Molecular Structure; Nitrogen; Nitrosamines; Quaternary Ammonium Compounds; Wastewater; Water Pollutants, Chemical; Water Purification | 2018 |
Metformin suppresses the esophageal carcinogenesis in rats treated with NMBzA through inhibiting AMPK/mTOR signaling pathway.
Topics: AMP-Activated Protein Kinases; Animals; Carcinogenesis; Carcinogens; Cell Proliferation; Dimethylnitrosamine; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Hypoglycemic Agents; Male; Metformin; Rats; Rats, Inbred F344; TOR Serine-Threonine Kinases; Tumor Cells, Cultured | 2019 |
A Cautionary Tale: Quantitative LC-HRMS Analytical Procedures for the Analysis of N-Nitrosodimethylamine in Metformin.
Topics: Chromatography, Liquid; Dimethylnitrosamine; Drug Contamination; Mass Spectrometry; Metformin; Nitrosamines; United States; United States Food and Drug Administration | 2020 |
Determination of N-nitrosodimethylamine and N-nitrosomethylethylamine in drug substances and products of sartans, metformin and ranitidine by precipitation and solid phase extraction and gas chromatography-tandem mass spectrometry.
Topics: Angiotensin II Type 1 Receptor Blockers; Dimethylnitrosamine; Gas Chromatography-Mass Spectrometry; Metformin; Pharmaceutical Preparations; Ranitidine; Solid Phase Extraction; Tandem Mass Spectrometry | 2020 |
Topics: Artifacts; Calibration; Dimethylnitrosamine; Drug Contamination; Drug Design; Europe; Gas Chromatography-Mass Spectrometry; Limit of Detection; Linear Models; Metformin; Pharmaceutical Preparations; Powders; Solvents; Tablets; Tandem Mass Spectrometry; Temperature | 2020 |
Insight into the formation of N-nitrosodimethylamine in metformin products.
Topics: Chromatography, High Pressure Liquid; Chromatography, Liquid; Dimethylnitrosamine; Drug Contamination; Metformin; Reproducibility of Results; Tandem Mass Spectrometry | 2021 |
Investigating the root cause of N-nitrosodimethylamine formation in metformin pharmaceutical products.
Topics: Chemistry, Pharmaceutical; Delayed-Action Preparations; Dimethylnitrosamine; Drug Compounding; Drug Contamination; Excipients; Hot Temperature; Humans; Metformin; Nitrates; Nitrites; Tablets; Water | 2021 |
Investigating the root cause of N-nitrosodimethylamine formation in metformin pharmaceutical products.
Topics: Dimethylnitrosamine; Drug Contamination; Humans; Metformin | 2022 |
Reply to the article 'Investigating the root cause of N- nitrosodimethylamine formation in metformin pharmaceutical products'.
Topics: Dimethylnitrosamine; Drug Contamination; Humans; Metformin; Pharmaceutical Preparations | 2022 |
NDMA analytics in metformin products: Comparison of methods and pitfalls.
Topics: Chromatography, Liquid; Dimethylnitrosamine; Gas Chromatography-Mass Spectrometry; Metformin; Tandem Mass Spectrometry | 2022 |
Avoiding N-nitrosodimethylamine formation in metformin pharmaceuticals by limiting dimethylamine and nitrite.
Topics: Dimethylamines; Dimethylnitrosamine; Excipients; Humans; Metformin; Nitrites | 2022 |
In-use stability assessment of FDA approved metformin immediate release and extended release products for N-Nitrosodimethylamine and dissolution quality attributes.
Topics: Dimethylnitrosamine; Hypoglycemic Agents; Metformin; Solubility; Tablets | 2022 |
Evaluation and optimization of a HS-SPME-assisted GC-MS/MS method for monitoring nitrosamine impurities in diverse pharmaceuticals.
Topics: Angiotensin II Type 1 Receptor Blockers; Diethylnitrosamine; Dimethylnitrosamine; Gas Chromatography-Mass Spectrometry; Metformin; Nitrosamines; Pharmaceutical Preparations; Ranitidine; Sodium Chloride; Solid Phase Microextraction; Tandem Mass Spectrometry | 2022 |
N-Nitrosodimethylamine formation in metformin hydrochloride sustained-release tablets: Effects of metformin and hypromellose used in drug product formulation.
Topics: Chromatography, Liquid; Delayed-Action Preparations; Dimethylnitrosamine; Excipients; Hypromellose Derivatives; Metformin; Nitrates; Nitrites; Nitrosamines; Peroxides; Tablets; Tandem Mass Spectrometry; Water | 2023 |
Analysis of N-nitrosodimethylamine in metformin hydrochloride products by high-resolution accurate mass gas chromatography mass spectrometry.
Topics: Dimethylnitrosamine; Gas Chromatography-Mass Spectrometry; Mass Spectrometry; Metformin; Pharmaceutical Preparations | 2023 |
Dispersant-First Dispersive Liquid-Liquid Microextraction (DF-DLLME), a Novel Sample Preparation Procedure for NDMA Determination in Metformin Products.
Topics: Dimethylnitrosamine; Gas Chromatography-Mass Spectrometry; Humans; Liquid Phase Microextraction; Metformin | 2023 |