metformin has been researched along with diazoxide in 20 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.00) | 18.7374 |
| 1990's | 3 (15.00) | 18.2507 |
| 2000's | 8 (40.00) | 29.6817 |
| 2010's | 8 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Jaffiol, C; Mary, P; Mirouze, J | 1 |
| Daher, A; Diamond, T; Howes, LG; Lykos, D; Morris, R; Sundaresan, P | 1 |
| Nestler, JE | 1 |
| Hompes, PG; Lambalk, CB; van Hooff, MH; van Montfrans, JM | 1 |
| Taylor, AE | 1 |
| Abbink, EJ; Jansen van Rosendaal, A; Lutterman, JA; Pickkers, P; Russel, FG; Smits, P; Tack, CJ | 1 |
| Grill, V; Kollind, M; Qvigstad, E | 1 |
| Fowler, A; Galiñanes, M; Hassouna, A; Loubani, M; Matata, BM; Standen, NB | 1 |
| Almoznino-Sarafian, D; Alon, I; Berman, S; Cohen, N; Efrati, S; Gorelik, O; Shteinshnaider, M; Weissgarten, J | 1 |
| Grill, V; Kollind, M; Qvigstad, E; Radtke, M | 1 |
| Covey, SD; Donald, C; Gray, SL; Jetha, A; Kieffer, TJ | 1 |
| Brandon, T; de Boer, H; Filius, M; Hermus, A; Loves, S; Mekking, M; Tack, CJ; van Groningen, L | 1 |
4 review(s) available for metformin and diazoxide
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Role of hyperinsulinemia in the pathogenesis of the polycystic ovary syndrome, and its clinical implications.
Topics: Adrenal Glands; Androgens; Anovulation; Chromans; Diazoxide; Female; Humans; Hyperinsulinism; Hypoglycemic Agents; Insulin; Insulin Resistance; Metformin; Ovary; Polycystic Ovary Syndrome; Steroid 17-alpha-Hydroxylase; Thiazoles; Thiazolidinediones; Troglitazone | 1997 |
Treatment of hyperinsulinaemia in polycystic ovary syndrome?
Topics: Chromans; Diazoxide; Female; Humans; Hyperinsulinism; Hypoglycemic Agents; Metformin; Polycystic Ovary Syndrome; Thiazoles; Thiazolidinediones; Troglitazone | 1998 |
Insulin-lowering medications in polycystic ovary syndrome.
Topics: Diazoxide; Female; Humans; Hyperandrogenism; Hyperinsulinism; Hypoglycemic Agents; Insulin Resistance; Menstruation Disturbances; Metformin; Polycystic Ovary Syndrome; Thiazoles; Thiazolidinediones | 2000 |
6 trial(s) available for metformin and diazoxide
| Article | Year |
|---|---|
Comparative effects of glibenclamide and metformin on ambulatory blood pressure and cardiovascular reactivity in NIDDM.
Topics: Acetylcholine; Adult; Aged; Angiotensin II; Blood Glucose; Blood Pressure; Cholesterol; Cross-Over Studies; Diabetes Mellitus, Type 2; Diazoxide; Double-Blind Method; Female; Forearm; Glyburide; Heart Rate; Hemodynamics; Humans; Hypoglycemic Agents; Infusions, Intra-Arterial; Lipoproteins; Male; Metformin; Middle Aged; Nitroprusside; Norepinephrine; Regional Blood Flow; Vascular Resistance | 1997 |
Treatment of hyperinsulinaemia in polycystic ovary syndrome?
Topics: Chromans; Diazoxide; Female; Humans; Hyperinsulinism; Hypoglycemic Agents; Metformin; Polycystic Ovary Syndrome; Thiazoles; Thiazolidinediones; Troglitazone | 1998 |
Vascular effects of glibenclamide vs. glimepiride and metformin in Type 2 diabetic patients.
Topics: Acetylcholine; Adult; Aged; Blood Flow Velocity; Blood Pressure; Body Mass Index; Body Weight; C-Peptide; Cross-Over Studies; Diabetes Mellitus, Type 2; Diazoxide; Dipyridamole; Double-Blind Method; Female; Forearm; Glyburide; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Sulfonylurea Compounds; Vasodilation | 2002 |
Nine weeks of bedtime diazoxide is well tolerated and improves beta-cell function in subjects with Type 2 diabetes.
Topics: Blood Glucose; Diabetes Mellitus, Type 2; Diazoxide; Double-Blind Method; Drug Administration Schedule; Female; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin; Islets of Langerhans; Male; Metformin | 2004 |
Twelve weeks' treatment with diazoxide without insulin supplementation in Type 2 diabetes is feasible but does not improve insulin secretion.
Topics: Carbamates; Diabetes Mellitus, Type 2; Diazoxide; Dose-Response Relationship, Drug; Female; Humans; Hypoglycemic Agents; Insulin; Insulin Secretion; Insulin-Secreting Cells; Male; Metformin; Middle Aged; Piperidines; Treatment Outcome | 2007 |
High-Dose, Diazoxide-Mediated Insulin Suppression Boosts Weight Loss Induced by Lifestyle Intervention.
Topics: Adult; Blood Glucose; Body Mass Index; Body Weight; Diazoxide; Dose-Response Relationship, Drug; Double-Blind Method; Healthy Lifestyle; Humans; Hyperglycemia; Hyperinsulinism; Hypoglycemic Agents; Insulin; Insulin Antagonists; Male; Metformin; Middle Aged; Obesity; Potassium Channels; Treatment Outcome; Weight Loss | 2018 |
11 other study(ies) available for metformin and diazoxide
| Article | Year |
|---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
[Extragonadal endocrine manifestations of Klinefelter's disease].
Topics: Adrenal Gland Diseases; Adult; Antibodies; Autoantibodies; Blood Glucose; Diabetes Mellitus; Diazoxide; Endocrine System Diseases; Glucose; Humans; Hypoglycemia; Insulin; Klinefelter Syndrome; Male; Metformin; Obesity; Pituitary Diseases; Thyroid Diseases; Thyroid Gland | 1973 |
Mitochondrial dysfunction as the cause of the failure to precondition the diabetic human myocardium.
Topics: Adenosine; Adrenergic alpha-Agonists; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diazoxide; Enzyme Activation; Glyburide; Heart Atria; Humans; Hypoglycemic Agents; In Vitro Techniques; Ischemic Preconditioning, Myocardial; Membrane Potentials; Metformin; Mitochondria, Heart; Myocardial Ischemia; p38 Mitogen-Activated Protein Kinases; Phenylephrine; Potassium Channels; Protein Kinase C; Reactive Oxygen Species; Tetradecanoylphorbol Acetate | 2006 |
Total cellular calcium and magnesium content of cultured human peripheral blood mononuclear cells following exposure to antidiabetic drugs.
Topics: Adult; Calcium; Cells, Cultured; Diazoxide; Glyburide; Humans; Hypoglycemic Agents; Leukocytes; Magnesium; Metformin; Middle Aged; Potassium Channels; Rosiglitazone; Thiazolidinediones | 2006 |
Hyperinsulinemia precedes insulin resistance in mice lacking pancreatic beta-cell leptin signaling.
Topics: Adiposity; Animals; Blood Glucose; Body Weight; Diazoxide; Eating; Female; Hyperinsulinism; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulin-Secreting Cells; Male; Metformin; Mice; Mice, Knockout; Receptors, Leptin | 2010 |