metformin has been researched along with d-alpha tocopherol in 42 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (2.38) | 18.2507 |
| 2000's | 11 (26.19) | 29.6817 |
| 2010's | 25 (59.52) | 24.3611 |
| 2020's | 5 (11.90) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Fülöp, T; Khalil, A; Maheux, P; Tessier, D | 1 |
| Bischoff, A | 1 |
| Shen, W | 1 |
| Bugianesi, E; David, E; Gentilcore, E; Manini, R; Marchesini, G; Natale, S; Rizzetto, M; Vanni, E; Villanova, N | 1 |
| Comar, KM; Sterling, RK | 1 |
| Lavine, JE; Schwimmer, JB | 1 |
| Kadayifci, A; Merriman, RB | 1 |
| Alessandri, C; Angelico, F; Burattin, M; Del Ben, M; Lirussi, F | 1 |
| Barclay, D; Faure, P; Halimi, S; Joyeux-Faure, M | 1 |
| Kleiner, D; Lavine, JE; Molleston, J; Patton, HM; Schwimmer, JB; Van Natta, ML | 1 |
| Calignano, A; Canani, RB; Cuzzocrea, S; Esposito, E; Iacono, A; Meli, R; Pacilio, M; Raso, GM | 1 |
| Dhawan, A; Dziechciarz, P; Horvath, A; Socha, P; Szajewska, H; Vajro, P | 1 |
| Abrams, SH; Brunt, EM; Lavine, JE; Molleston, JP; Murray, KF; Robuck, PR; Rosenthal, P; Sanyal, AJ; Scheimann, AO; Schwimmer, JB; Tonascia, J; Unalp, A | 1 |
| Álvarez Ferre, J; González Jiménez, E; Schmidt Río-Valle, J | 1 |
| Abrams, SH; Brunt, EM; Chalasani, N; Clark, JM; Hoofnagle, JH; Kleiner, DE; Lavine, JE; Molleston, JP; Murray, KF; Robuck, PR; Rosenthal, P; Sanyal, AJ; Scheimann, AO; Schwimmer, JB; Tonascia, J; Ünalp, A; Van Natta, ML | 1 |
| Alisi, A; Nobili, V | 1 |
| Andrews, DB; Lavine, JE | 1 |
| Brunt, EM; Chalasani, N; Charlton, M; Cusi, K; Diehl, AM; Lavine, JE; Sanyal, AJ; Younossi, Z | 1 |
| Akcam, M; Boyaci, A; Dundar, BN; Kaya, S; Pirgon, O; Uysal, S | 1 |
| Beiraghdar, F; Ghamarchehreh, ME; Jalalian, HR; Panahi, Y; Sahebkar, A; Zare, R | 1 |
| Azzouzi, AR; Cancel-Tassin, G; Cussenot, O; Eisinger, F; Gravis, G; Rossi, D | 1 |
| Aviram, M; Hayek, T; Koren-Gluzer, M | 1 |
| Ding, XD; Fan, JG; Han, Y; Ma, AL; Shi, JP; Xu, Y | 1 |
| Henry, L; Mehta, R; Mishra, A; Reyes, MJ; Younossi, ZM | 1 |
| Halilbasic, E; Hofer, H; Kazemi-Shirazi, L; Kienbacher, C; Munda, P; Rechling, C; Trauner, M; Traussnigg, S | 1 |
| Ganesh, S; Rustgi, VK | 1 |
| Depeš, D; Falk, M; Hofer, M; Hoferová, Z | 1 |
| Moradi, A; Rafiei, F; Talaei, A | 1 |
| Al-Ajmi, HN; Al-Amin, MA; Al-Barrak, HS; Al-Hassab, SA; Al-Rabeeah, DA; Al-Rasheed, NM; Al-Salman, SA; Al-Shammari, TK; Hasan, IH; Ibrahim, SA | 1 |
| Boniecka, I; Czerwonogrodzka-Senczyna, A; Ostrowska, J; Sarosiekjeznach-Steinhagen, A | 1 |
| Akash, MSH; Munawar, SM; Rehman, K; Saeed, K | 1 |
| El-Aal, AA; El-Ghffar, EAA; Ghali, AA; Sirdah, MM; Zughbur, MR | 1 |
| Akbarzadeh, A; Rahimi, M; Salehi, R; Samadi, N; Shafiei-Irannejad, V; Yousefi, B; Zarghami, N | 1 |
| Alkhouri, N; Conjeevaram Selvakumar, PK; Kabbany, MN | 1 |
| Anushiravani, A; Haddadi, N; Mohammadkarimi, V; Pourfarmanbar, M | 1 |
| Atkin, SL; De Vincentis, A; Jamialahmadi, T; Mahjoubin-Tehran, M; Mantzoros, CS; Mikhailidis, DP; Sahebkar, A | 1 |
| Kohli, R; Lin, CH | 1 |
| Chalasani, N; Cummings, OW; Gawrieh, S; Harlow, KE; Molleston, JP; Pike, F; Rosenberg, WM; Wilson, LA; Yates, KP | 1 |
| Ahmadi-Juoibari, T; Aneva, IY; Ataee, M; Bahrami, G; Farzaei, MH; Heydarpour, F; Majnooni, MB | 1 |
| Beheshtirouy, S; Gharekhani, A; Khoshbaten, M; Rezaee, H; Shayanrad, S | 1 |
14 review(s) available for metformin and d-alpha tocopherol
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Review article: Drug therapy for non-alcoholic fatty liver disease.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antioxidants; Ascorbic Acid; Betaine; Cholagogues and Choleretics; Enzyme Inhibitors; Fatty Liver; Humans; Hypoglycemic Agents; Lipotropic Agents; Metformin; Pentoxifylline; Probucol; Thiazolidinediones; Ursodeoxycholic Acid; Vitamin E | 2006 |
Drugs improving insulin resistance for non-alcoholic fatty liver disease and/or non-alcoholic steatohepatitis.
Topics: Alanine Transaminase; Aspartate Aminotransferases; Fatty Liver; Humans; Hypoglycemic Agents; Insulin Resistance; Metformin; Randomized Controlled Trials as Topic; Vitamin E; Vitamins | 2007 |
Pharmacological interventions for nonalcoholic fatty liver disease in adults and in children: a systematic review.
Topics: Acetylcysteine; Adult; Alanine Transaminase; Aspartate Aminotransferases; Carnitine; Child; Dietary Supplements; Drug Synergism; Drug Therapy, Combination; Fatty Liver; Humans; Hypoglycemic Agents; Liver; Metformin; Pioglitazone; Probucol; Randomized Controlled Trials as Topic; Thiazolidinediones; Ursodeoxycholic Acid; Vitamin E | 2009 |
[Fatty liver and its clinical management in obese adolescents].
Topics: Adiponectin; Adolescent; Apoptosis; Biomarkers; Chemokines; Disease Progression; Fatty Liver; Fibrosis; Hepatocytes; Humans; Hypertriglyceridemia; Insulin Resistance; Kupffer Cells; Liver Cirrhosis; Liver Transplantation; Metformin; Models, Biological; Non-alcoholic Fatty Liver Disease; Obesity; Oxidative Stress; Ursodeoxycholic Acid; Vitamin E | 2011 |
[Pharmaco and diet based prostate cancer prevention].
Topics: 5-alpha Reductase Inhibitors; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Diet; Eflornithine; Fruit; Histone Deacetylase Inhibitors; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemic Agents; Male; Metformin; Minerals; Prostatic Neoplasms; Selective Estrogen Receptor Modulators; Selenium; Vegetables; Vitamin D; Vitamin E; Vitamins | 2013 |
Systematic review with meta-analysis: non-alcoholic steatohepatitis - a case for personalised treatment based on pathogenic targets.
Topics: Bariatric Surgery; Fatty Liver; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lactones; Metabolic Syndrome; Metformin; Non-alcoholic Fatty Liver Disease; Orlistat; Precision Medicine; Thiazolidinediones; Ursodeoxycholic Acid; Vitamin E; Weight Loss | 2014 |
Challenges and Management of Liver Cirrhosis: Practical Issues in the Therapy of Patients with Cirrhosis due to NAFLD and NASH.
Topics: Anticholesteremic Agents; Antioxidants; Bariatric Surgery; Carcinoma, Hepatocellular; Disease Progression; Genetic Variation; Humans; Hypoglycemic Agents; Lipase; Liver; Liver Cirrhosis; Liver Neoplasms; Liver Transplantation; Membrane Proteins; Metabolic Syndrome; Metformin; Non-alcoholic Fatty Liver Disease; Obesity, Morbid; Prognosis; Receptors, Cytoplasmic and Nuclear; Vitamin E | 2015 |
Current Pharmacologic Therapy for Nonalcoholic Fatty Liver Disease.
Topics: Angiotensin Receptor Antagonists; Anti-Inflammatory Agents, Non-Steroidal; Anti-Obesity Agents; Anticholesteremic Agents; Antioxidants; Cannabinoid Receptor Antagonists; Cholagogues and Choleretics; Fatty Acids, Omega-3; Glucagon-Like Peptide-1 Receptor; Humans; Hypoglycemic Agents; Insulin Resistance; Lactones; Metformin; Non-alcoholic Fatty Liver Disease; Orlistat; Pentoxifylline; Piperidines; Probiotics; Pyrazoles; Rimonabant; Synbiotics; Thiazolidinediones; Ursodeoxycholic Acid; Vitamin E | 2016 |
Combining Pharmacological Countermeasures to Attenuate the Acute Radiation Syndrome-A Concise Review.
Topics: Acute Radiation Syndrome; Amifostine; Animals; Dinoprostone; Drug Administration Schedule; Drug Combinations; Drug Synergism; Granulocyte Colony-Stimulating Factor; Humans; Metformin; Misoprostol; Radiation Injuries, Experimental; Radiation-Protective Agents; Vitamin E | 2017 |
[Non-alcoholic liver disease - diagnosis and treatment].
Topics: Biopsy; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemic Agents; Metformin; Non-alcoholic Fatty Liver Disease; Vitamin E | 2017 |
Nonalcoholic Fatty Liver Disease in Children: Not a Small Matter.
Topics: Adolescent; Bariatric Surgery; Child; Diet Therapy; Humans; Metformin; Non-alcoholic Fatty Liver Disease; Prevalence; Vitamin E | 2018 |
Non-alcoholic fatty liver disease and steatohepatitis: State of the art on effective therapeutics based on the gold standard method for diagnosis.
Topics: Biopsy; Disease Progression; Humans; Liver; Liver Cirrhosis; Metformin; Non-alcoholic Fatty Liver Disease; Pentoxifylline; Pioglitazone; Randomized Controlled Trials as Topic; Rosiglitazone; Severity of Illness Index; Treatment Outcome; Ursodeoxycholic Acid; Vitamin E | 2021 |
Emerging New Diagnostic Modalities and Therapies of Nonalcoholic Fatty Liver Disease.
Topics: Adolescent; Alanine Transaminase; Antioxidants; Bariatric Surgery; Child; Child, Preschool; Cysteamine; Cystine Depleting Agents; Delayed-Action Preparations; Diet; Humans; Hypoglycemic Agents; Infant; Infant, Newborn; Life Style; Liver Cirrhosis; Metformin; Non-alcoholic Fatty Liver Disease; Pediatric Obesity; Vitamin E | 2020 |
13 trial(s) available for metformin and d-alpha tocopherol
| Article | Year |
|---|---|
Effects of gliclazide versus metformin on the clinical profile and lipid peroxidation markers in type 2 diabetes.
Topics: Aged; Biomarkers; Diabetes Mellitus, Type 2; Female; Gliclazide; Humans; Hypoglycemic Agents; Lipid Peroxides; Lipoproteins, HDL; Lipoproteins, LDL; Male; Metformin; Middle Aged; Treatment Outcome; Vitamin E | 1999 |
A randomized controlled trial of metformin versus vitamin E or prescriptive diet in nonalcoholic fatty liver disease.
Topics: Adult; Aged; Alanine Transaminase; Antioxidants; Aspartate Aminotransferases; Biopsy; Body Mass Index; Diet, Reducing; Fatty Liver; Female; Follow-Up Studies; Hepatitis; Homeostasis; Humans; Hypoglycemic Agents; Insulin Resistance; Liver Cirrhosis; Male; Metabolic Syndrome; Metformin; Middle Aged; Treatment Outcome; Vitamin E | 2005 |
Clinical correlates of histopathology in pediatric nonalcoholic steatohepatitis.
Topics: Adolescent; Alanine Transaminase; Antioxidants; Aspartate Aminotransferases; Biopsy; Child; Drug Therapy, Combination; Fatty Liver; Female; Follow-Up Studies; Hematocrit; Humans; Hypoglycemic Agents; Leukocyte Count; Liver; Male; Metformin; Predictive Value of Tests; Prevalence; Prognosis; Prospective Studies; ROC Curve; Severity of Illness Index; Vitamin E | 2008 |
Treatment of nonalcoholic fatty liver disease in children: TONIC trial design.
Topics: Adolescent; Alanine Transaminase; Child; Double-Blind Method; Fatty Liver; Female; Humans; Hypoglycemic Agents; Liver Function Tests; Male; Metformin; Patient Selection; Research Design; Vitamin E | 2010 |
Effect of vitamin E or metformin for treatment of nonalcoholic fatty liver disease in children and adolescents: the TONIC randomized controlled trial.
Topics: Adolescent; Alanine Transaminase; Antioxidants; Child; Double-Blind Method; Fatty Liver; Female; Humans; Hypoglycemic Agents; Male; Metformin; Non-alcoholic Fatty Liver Disease; Obesity; Severity of Illness Index; Treatment Outcome; Vitamin E | 2011 |
Investigation of the effects of Chlorella vulgaris supplementation in patients with non-alcoholic fatty liver disease: a randomized clinical trial.
Topics: Adult; Aged; Alanine Transaminase; Alkaline Phosphatase; Antioxidants; Aspartate Aminotransferases; Bilirubin; Biomarkers; Blood Glucose; Blood Pressure; Chi-Square Distribution; Chlorella vulgaris; Drug Therapy, Combination; Fatty Liver; Female; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Iran; Male; Metformin; Middle Aged; Non-alcoholic Fatty Liver Disease; Plant Preparations; Serum Albumin; Serum Albumin, Human; Time Factors; Treatment Outcome; Triglycerides; Uric Acid; Vitamin E; Weight Loss | 2012 |
Randomized, vitamin E-controlled trial of bicyclol plus metformin in non-alcoholic fatty liver disease patients with impaired fasting glucose.
Topics: Alanine Transaminase; Biphenyl Compounds; Drug Therapy, Combination; Female; Humans; Hypoglycemia; Liver; Male; Metformin; Non-alcoholic Fatty Liver Disease; Vitamin E | 2014 |
The evaluation of the effect of metformin on breast fibrocystic disease.
Topics: Adolescent; Adult; AMP-Activated Protein Kinases; Double-Blind Method; Female; Fibrocystic Breast Disease; Humans; Metformin; Vitamin E; Young Adult | 2017 |
The effect of vitamin C and/or E supplementations on type 2 diabetic adult males under metformin treatment: A single-blinded randomized controlled clinical trial.
Topics: Adult; Antioxidants; Ascorbic Acid; Biomarkers; Blood Glucose; Case-Control Studies; Diabetes Mellitus, Type 2; Dietary Supplements; Drug Synergism; Female; Follow-Up Studies; Glycated Hemoglobin; Hematologic Tests; Humans; Hypoglycemic Agents; Insulin Resistance; Kidney Function Tests; Lipids; Liver Function Tests; Male; Metformin; Middle Aged; Middle East; Oxidative Stress; Prognosis; Single-Blind Method; Vitamin E; Vitamins | 2018 |
Treatment options for nonalcoholic fatty liver disease: a double-blinded randomized placebo-controlled trial.
Topics: Adolescent; Adult; Aged; Alanine Transaminase; Aspartate Aminotransferases; Biomarkers; Blood Glucose; Body Mass Index; Double-Blind Method; Female; Humans; Iran; Lipids; Male; Metformin; Middle Aged; Non-alcoholic Fatty Liver Disease; Pioglitazone; Risk Reduction Behavior; Silymarin; Time Factors; Treatment Outcome; Vitamin E; Waist Circumference; Young Adult | 2019 |
Relationship of Enhanced Liver Fibrosis Score with Pediatric Nonalcoholic Fatty Liver Disease Histology and Response to Vitamin E or Metformin.
Topics: Adolescent; Area Under Curve; Biopsy; Child; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hypoglycemic Agents; Liver; Liver Cirrhosis; Logistic Models; Male; Metformin; Non-alcoholic Fatty Liver Disease; Odds Ratio; ROC Curve; Severity of Illness Index; Treatment Outcome; Vitamin E; Vitamins | 2021 |
The effects of co-administration of artichoke leaf extract supplementation with metformin and vitamin E in patients with nonalcoholic fatty liver disease: A randomized clinical trial.
Topics: Alanine Transaminase; Cynara scolymus; Dietary Supplements; Humans; Liver; Metformin; Non-alcoholic Fatty Liver Disease; Plant Extracts; Vitamin E | 2021 |
Comparison of the efficacy of pioglitazone and metformin on ultrasound grade and liver enzymes level in patients with non-alcoholic fatty liver disease: A randomized controlled clinical trial.
Topics: Alanine Transaminase; Aspartate Aminotransferases; Humans; Hypoglycemic Agents; Metformin; Non-alcoholic Fatty Liver Disease; Pioglitazone; Vitamin E | 2023 |
15 other study(ies) available for metformin and d-alpha tocopherol
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
[Fatty liver and raised gamma-GT: it can happen to abstainers, too].
Topics: Cholagogues and Choleretics; Clinical Enzyme Tests; Diabetes Complications; Diagnosis, Differential; Fatty Liver; Female; gamma-Glutamyltransferase; Humans; Hypoglycemic Agents; Male; Metformin; Obesity; Risk Factors; Ursodeoxycholic Acid; Vitamin E | 2002 |
[Drug therapy for nonalcoholic fatty liver disease].
Topics: Antioxidants; Fatty Liver; Humans; Hypoglycemic Agents; Hypolipidemic Agents; Metformin; Quaternary Ammonium Compounds; Vitamin E | 2005 |
Clinical Research Network launches TONIC trial for treatment of nonalcoholic fatty liver disease in children.
Topics: Adolescent; Antioxidants; Child; Clinical Trials as Topic; Data Collection; Fatty Liver; Female; Humans; Hypoglycemic Agents; Male; Metformin; Obesity; Vitamin E | 2006 |
Metformin, vitamin E, and diet for patients with nonalcoholic fatty liver disease.
Topics: Adult; Aged; Alanine Transaminase; Antioxidants; Aspartate Aminotransferases; Biopsy; Body Mass Index; Diet, Reducing; Fatty Liver; Female; Hepatitis; Homeostasis; Humans; Hypoglycemic Agents; Insulin Resistance; Liver Cirrhosis; Male; Metabolic Syndrome; Metformin; Middle Aged; Treatment Outcome; Vitamin E | 2006 |
Comparison of the effects of zinc alone and zinc associated with selenium and vitamin E on insulin sensitivity and oxidative stress in high-fructose-fed rats.
Topics: Animals; Antioxidants; Diet; Dietary Carbohydrates; Fructose; Glucose Clamp Technique; Hypoglycemic Agents; Insulin; Insulin Resistance; Lipids; Male; Metformin; Micronutrients; Oxidation-Reduction; Oxidative Stress; Proteins; Rats; Rats, Wistar; Selenium; Vitamin E; Zinc | 2007 |
Comparative therapeutic effects of metformin and vitamin E in a model of non-alcoholic steatohepatitis in the young rat.
Topics: Animals; Antioxidants; Blotting, Western; Body Weight; Disease Models, Animal; Fatty Liver; Lipid Peroxidation; Liver; Male; Metformin; Rats; Rats, Sprague-Dawley; Vitamin E | 2009 |
Nonalcoholic fatty liver disease: Targeted therapy in children--what is the right way?
Topics: Adolescent; Alanine Transaminase; Child; Fatty Liver; Humans; Life Style; Metformin; Non-alcoholic Fatty Liver Disease; Treatment Outcome; Vitamin E | 2011 |
Medical therapy for nonalcoholic fatty liver disease in children and adolescents.
Topics: Adolescent; Biopsy; Child; Fatty Liver; Humans; Hypoglycemic Agents; Liver; Metformin; Non-alcoholic Fatty Liver Disease; Vitamin E; Vitamins | 2012 |
The diagnosis and management of non-alcoholic fatty liver disease: practice Guideline by the American Association for the Study of Liver Diseases, American College of Gastroenterology, and the American Gastroenterological Association.
Topics: Fatty Liver; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Life Style; Metformin; Non-alcoholic Fatty Liver Disease; Prevalence; Risk Factors; Thiazolidinediones; Vitamin E | 2012 |
Therapeutic effect of metformin and vitamin E versus prescriptive diet in obese adolescents with fatty liver.
Topics: Adiponectin; Adolescent; Cholesterol, LDL; Fatty Liver; Female; Humans; Hypoglycemic Agents; Insulin Resistance; Male; Metformin; Non-alcoholic Fatty Liver Disease; Obesity; Tumor Necrosis Factor-alpha; Vitamin E | 2011 |
Metformin inhibits macrophage cholesterol biosynthesis rate: possible role for metformin-induced oxidative stress.
Topics: Animals; Antioxidants; Cell Line; Cholesterol; Hypoglycemic Agents; Macrophages; Metformin; Mice; Oxidative Stress; Vitamin E | 2013 |
Possible protective mechanisms exerted by metformin or metformin and vitamin E in isoproterenol-induced cardiac injury.
Topics: Animals; Heart Injuries; Isoproterenol; Male; Metformin; NF-kappa B; Rats; Rats, Wistar; Signal Transduction; Vitamin E | 2018 |
Resveratrol regulates hyperglycemia-induced modulations in experimental diabetic animal model.
Topics: Animals; Antioxidants; Blood Glucose; Calcium; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Hyperglycemia; Insulin; Insulin Resistance; Magnesium; Male; Metformin; Rats; Resveratrol; Stilbenes; Vitamin E | 2018 |
Reversion of Multidrug Resistance by Co-Encapsulation of Doxorubicin and Metformin in Poly(lactide-co-glycolide)-d-α-tocopheryl Polyethylene Glycol 1000 Succinate Nanoparticles.
Topics: Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B; Breast Neoplasms; Doxorubicin; Drug Compounding; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Female; Humans; MCF-7 Cells; Metformin; Nanoparticles; Polylactic Acid-Polyglycolic Acid Copolymer; Vitamin E | 2018 |