metformin and cytochrome c-t

metformin has been researched along with cytochrome c-t in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (15.38)29.6817
2010's9 (69.23)24.3611
2020's2 (15.38)2.80

Authors

AuthorsStudies
Batandier, C; Chauvin, C; De Oliveira, F; Detaille, D; Fontaine, E; Guigas, B; Leverve, X1
Almeida, A; Attia, S; Delgado-Esteban, M; Detaille, D; El-Mir, MY; Fontaine, E; Guigas, B; Leverve, X; R-Villanueva, G1
Arévalo, M; Briones, E; Detaille, D; El-Mir, MY; Leverve, X; López-Novoa, JM; Morales, AI; Prieto, M; Puente, A1
Kim, MO; Lee, HY; Naseer, MI; Ullah, I; Ullah, N1
Dela, F; Helge, JW; Kristensen, JM; Larsen, S; Wojtaszewski, JF1
El Sarha, A; Ismail, MA; Refaat, R; Salman, ZK; Selima, E1
Asensio-Lopez, MC; de Torre, C; Lax, A; Pascual-Figal, DA; Sanchez-Mas, J; Valdes, M1
Chen, HM; Chen, YL; Cheng, YC; Chiang, MC; Chung, MM; Liang, YJ; Nicol, CJ; Pei, D; Sun, B; Yen, CH1
Cui, Y; Du, Y; Gu, H; Jiang, Y; Li, S; Liu, Q; Sun, C; Sun, R; Xiao, Y; Zhou, C; Zhuang, S1
Chen, SJ; Cheng, YC; Chiang, MC; Huang, RN; Yen, CH1
Chang, JZ; Hong, CY; Kok, SH; Lai, EH; Lin, SK; Su, IH; Wang, HW; Yang, CN; Yang, H1
He, H; Li, SSC; Liu, J; Liu, Z; Wen, Y1
Mini, S; Shyma, RL1

Other Studies

13 other study(ies) available for metformin and cytochrome c-t

ArticleYear
Metformin inhibits mitochondrial permeability transition and cell death: a pharmacological in vitro study.
    The Biochemical journal, 2004, Sep-15, Volume: 382, Issue:Pt 3

    Topics: Cell Death; Citrate (si)-Synthase; Cytochromes c; Electron Transport Complex I; Humans; Hypoglycemic Agents; Intracellular Membranes; Ion Channels; KB Cells; Metformin; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Oxygen Consumption; Permeability

2004
Neuroprotective role of antidiabetic drug metformin against apoptotic cell death in primary cortical neurons.
    Journal of molecular neuroscience : MN, 2008, Volume: 34, Issue:1

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cells, Cultured; Cerebral Cortex; Cyclosporine; Cytochromes c; Diabetic Neuropathies; Enzyme Inhibitors; Etoposide; Hypoglycemic Agents; Membrane Potential, Mitochondrial; Metformin; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Oxidative Stress; Rats; Rats, Wistar

2008
Metformin prevents experimental gentamicin-induced nephropathy by a mitochondria-dependent pathway.
    Kidney international, 2010, Volume: 77, Issue:10

    Topics: Acetylglucosaminidase; Animals; Antioxidants; Apoptosis; Cytochrome c Group; Cytochromes c; Electron Transport; Gentamicins; Hypoglycemic Agents; Kidney; Kidney Diseases; Lipid Peroxidation; Male; Metformin; Mitochondria; Oxidation-Reduction; Oxidative Stress; Permeability; Rats; Reactive Oxygen Species

2010
Neuroprotection with metformin and thymoquinone against ethanol-induced apoptotic neurodegeneration in prenatal rat cortical neurons.
    BMC neuroscience, 2012, Jan-19, Volume: 13

    Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Benzimidazoles; Benzoquinones; Calcium; Carbocyanines; Caspases; Cell Survival; Cells, Cultured; Central Nervous System Depressants; Cerebral Cortex; Cytochromes c; Embryo, Mammalian; Ethanol; Female; Fluoresceins; In Situ Nick-End Labeling; Indoles; Membrane Potential, Mitochondrial; Metformin; Neurons; Neuroprotective Agents; Organic Chemicals; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Pregnancy; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Statistics, Nonparametric

2012
Two weeks of metformin treatment enhances mitochondrial respiration in skeletal muscle of AMPK kinase dead but not wild type mice.
    PloS one, 2013, Volume: 8, Issue:1

    Topics: 3-Hydroxyacyl CoA Dehydrogenases; AMP-Activated Protein Kinases; Animals; Blotting, Western; Cell Respiration; Citrate (si)-Synthase; Cytochromes c; Electron Transport; Female; Metformin; Mice; Mice, Inbred C57BL; Mitochondria; Mitochondrial Proteins; Muscle, Skeletal; Phosphorylation; Phosphoserine; Pyruvate Dehydrogenase Complex; Substrate Specificity

2013
The combined effect of metformin and L-cysteine on inflammation, oxidative stress and insulin resistance in streptozotocin-induced type 2 diabetes in rats.
    European journal of pharmacology, 2013, Aug-15, Volume: 714, Issue:1-3

    Topics: Animals; Body Weight; C-Reactive Protein; Caspase 3; Chemokine CCL2; Cysteine; Cytochromes c; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Drug Interactions; Fatty Acids, Nonesterified; Glutathione; Inflammation; Insulin Resistance; Liver; Male; Malondialdehyde; Metformin; Nitrates; Nitrites; Oxidative Stress; Rats; Rats, Wistar

2013
Ferritin heavy chain as main mediator of preventive effect of metformin against mitochondrial damage induced by doxorubicin in cardiomyocytes.
    Free radical biology & medicine, 2014, Volume: 67

    Topics: Animals; Animals, Newborn; Antibiotics, Antineoplastic; Apoferritins; Apoptosis; Cardiotonic Agents; Caspase 3; Cell Line, Tumor; Cytochromes c; DNA Fragmentation; Doxorubicin; Gene Expression Regulation; Iron; Metformin; Mice; Mitochondria; Myocytes, Cardiac; NF-kappa B; Rats; RNA, Small Interfering; Signal Transduction

2014
The neuroprotective role of metformin in advanced glycation end product treated human neural stem cells is AMPK-dependent.
    Biochimica et biophysica acta, 2015, Volume: 1852, Issue:5

    Topics: AMP-Activated Protein Kinases; Blotting, Western; Caspase 3; Caspase 9; Cell Survival; Cells, Cultured; Cytochromes c; Gene Expression; Glycation End Products, Advanced; Humans; Hypoglycemic Agents; Metformin; Mitochondria; Neural Stem Cells; Nuclear Respiratory Factor 1; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; PPAR gamma; Proto-Oncogene Proteins c-bcl-2; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Signal Transduction; Transcription Factors

2015
Metformin prevents cerebellar granule neurons against glutamate-induced neurotoxicity.
    Brain research bulletin, 2016, Volume: 121

    Topics: Animals; Animals, Newborn; Apoptosis; Caspase 3; Cells, Cultured; Cerebellum; Cytochromes c; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Glutamic Acid; Male; MAP Kinase Kinase 4; MAP Kinase Signaling System; Metformin; Neurons; Neuroprotective Agents; Rats

2016
Metformin activation of AMPK-dependent pathways is neuroprotective in human neural stem cells against Amyloid-beta-induced mitochondrial dysfunction.
    Experimental cell research, 2016, 10-01, Volume: 347, Issue:2

    Topics: AMP-Activated Protein Kinases; Amyloid beta-Peptides; Cell Survival; Cyclic AMP Response Element-Binding Protein; Cytochromes c; Cytosol; Enzyme Activation; Gene Expression Regulation; Humans; Metformin; Mitochondria; Neural Stem Cells; Neuroprotective Agents; Proto-Oncogene Proteins c-bcl-2; Signal Transduction

2016
Metformin Ameliorates Periapical Lesions through Suppression of Hypoxia-induced Apoptosis of Osteoblasts.
    Journal of endodontics, 2018, Volume: 44, Issue:12

    Topics: Animals; Apoptosis; Caspase 9; Cell Hypoxia; Cells, Cultured; Cytochromes c; Depression, Chemical; Disease Models, Animal; Humans; Metformin; Mitochondria; Osteoblasts; Oxidative Stress; Periapical Diseases; Poly(ADP-ribose) Polymerases; Rats, Sprague-Dawley; Root Canal Irrigants; Superoxides

2018
Single-Cell Analysis of Signaling Proteins Provides Insights into Proapoptotic Properties of Anticancer Drugs.
    Analytical chemistry, 2020, 09-15, Volume: 92, Issue:18

    Topics: Antineoplastic Agents; Apoptosis; Caspase 3; Cell Line; Cell Proliferation; Cell Survival; Cytochromes c; Dactinomycin; Drug Screening Assays, Antitumor; Humans; Immunoassay; Kinetics; Metformin; Particle Size; Single-Cell Analysis; Surface Properties

2020
Neuroprotective effect of Morin via TrkB/Akt pathway against diabetes mediated oxidative stress and apoptosis in neuronal cells.
    Toxicology mechanisms and methods, 2022, Volume: 32, Issue:9

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Blood Glucose; Brain-Derived Neurotrophic Factor; Cytochromes c; Diabetes Mellitus; Flavones; Flavonoids; Glycated Hemoglobin; Hypoglycemic Agents; Insulins; Male; Metformin; Neuroprotective Agents; Oxidative Stress; Protein Carbonylation; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Streptozocin

2022