metformin and cyproterone acetate, ethinyl estradiol drug combination

metformin has been researched along with cyproterone acetate, ethinyl estradiol drug combination in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's10 (35.71)29.6817
2010's15 (53.57)24.3611
2020's3 (10.71)2.80

Authors

AuthorsStudies
Kelestimur, F; Sahin, Y1
Mitkov, M; Pekhlivanov, B; Terzieva, D1
Mitkov, M; Pehlivanov, B; Terzieva, D1
Alvarez-Blasco, F; Botella-Carretero, JI; Escobar-Morreale, HF; Lasunción, MA; Luque-Ramírez, M; Martínez-Bermejo, E1
Atanasova, I; Genchev, G; Kamenov, Z; Khristov, V; Kolarov, G; Milcheva, B; Orbetsova, M; Shigarminova, R; Zakharieva, S1
Alvarez-Blasco, F; Botella-Carretero, JI; Escobar-Morreale, HF; Luque-Ramírez, M; San Millán, JL; Sanchón, R1
Alvarez-Blasco, F; Escobar-Morreale, HF; Luque-Ramírez, M; Uriol Rivera, MG1
Jiang, M; Ma, F; Qi, J; Qiao, L; Wang, L; Xie, S; Xu, K; Yue, H; Zhang, W; Zhou, X1
Jing, Z; Liang-Zhi, X; Tai-Xiang, W; Ying, T; Yu-Jian, J1
del Rey Sánchez, JM; Escobar-Morreale, HF; Luque-Ramírez, M; Matíes, M; Mendieta-Azcona, C1
Gui, SQ; Kuek, S; Wang, WJ1
Chacón, MR; de Zegher, F; Díaz, M; Ibáñez, L; López-Bermejo, A; Maymó-Masip, E; Salvador, C; Vendrell, J1
Armutcu, F; Carlioglu, A; Gumus, II; Karakurt, F; Kasapoglu, B; Kaygusuz, I; Keskin, EA; Koca, C; Uysal, A; Uysal, S1
Aksoy, A; Carlioglu, A; Gozukara, I; Kabil Kucur, S; Kamalak, Z; Keskin, H; Uludag, EU1
Cahill, DJ; O'Brien, K1
Carter, B; Fedorowicz, Z; Pandis, N; van Zuuren, EJ1
Jin, J; Mueck, AO; Ruan, X; Wu, H1
Chen, A; Du, J; Du, Y; Liao, YC; Lin, XF; Wang, Y; Wu, C; Wu, RR; Ye, Y; Zhang, XB1
Feng, W; Jia, YY; Shi, HR; Zhang, DY1
de Zegher, F; Díaz, M; Gallego-Escuredo, JM; Ibáñez, L; Villarroya, F1
Cui, N; Feng, X; Hao, G; Wang, L; Xu, Y; Zhang, J; Zhao, Z1
Gu, M; Mueck, AO; Ruan, X; Song, J; Wang, H; Wang, L2
Mohanty, J; Nagy, A; Sahu, A; Tripathy, P1
Shi, Y; Tang, L; Ye, J; Zhu, X1
Huo, P; Jiang, Z; Le, J; Lei, X; Tang, Q; Tu, H; Yao, J; Zhang, R; Zhang, S1
Hu, H; Li, F; Li, W; Liu, J; Ma, Z; Zou, G1
Chen, X; Feng, Y; Li, X; Liu, Y; Wang, Y; Yao, D; Zhang, F1

Reviews

3 review(s) available for metformin and cyproterone acetate, ethinyl estradiol drug combination

ArticleYear
Medical treatment regimens of hirsutism.
    Reproductive biomedicine online, 2004, Volume: 8, Issue:5

    Topics: Androgen Antagonists; Cyproterone Acetate; Drug Combinations; Enzyme Inhibitors; Ethinyl Estradiol; Female; Finasteride; Flutamide; Hirsutism; Humans; Hypoglycemic Agents; Metformin; Mineralocorticoid Receptor Antagonists; Spironolactone

2004
The effects of Diane-35 and metformin in treatment of polycystic ovary syndrome: an updated systematic review.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2008, Volume: 24, Issue:10

    Topics: Algorithms; Androgen Antagonists; Cyproterone Acetate; Drug Combinations; Ethinyl Estradiol; Female; Humans; Hypoglycemic Agents; Metformin; Polycystic Ovary Syndrome; Treatment Outcome

2008
Interventions for hirsutism (excluding laser and photoepilation therapy alone).
    The Cochrane database of systematic reviews, 2015, Apr-28, Issue:4

    Topics: 5-alpha Reductase Inhibitors; Adult; Androgen Antagonists; Body Mass Index; Contraceptive Agents, Female; Cyproterone Acetate; Desogestrel; Drug Combinations; Eflornithine; Ethinyl Estradiol; Female; Finasteride; Flutamide; Hirsutism; Humans; Hypoglycemic Agents; Metformin; Quality of Life; Randomized Controlled Trials as Topic; Spironolactone

2015

Trials

12 trial(s) available for metformin and cyproterone acetate, ethinyl estradiol drug combination

ArticleYear
[Combined use of metformin and Diane35 in polycystic ovary syndrome].
    Akusherstvo i ginekologiia, 2004, Volume: 43, Issue:3

    Topics: Administration, Oral; Adolescent; Adult; Androgen Antagonists; Cyproterone Acetate; Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; Ethinyl Estradiol; Female; Humans; Metformin; Polycystic Ovary Syndrome; Prospective Studies; Treatment Outcome

2004
Combined use of metformin and ethinyl estradiol-cyproterone acetate in polycystic ovary syndrome.
    European journal of obstetrics, gynecology, and reproductive biology, 2005, Feb-01, Volume: 118, Issue:2

    Topics: Adult; Androgen Antagonists; Body Mass Index; Cyproterone Acetate; Dehydroepiandrosterone Sulfate; Drug Combinations; Drug Therapy, Combination; Ethinyl Estradiol; Female; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Metformin; Polycystic Ovary Syndrome; Prospective Studies; Sex Hormone-Binding Globulin; Testosterone; Waist-Hip Ratio

2005
Comparison of ethinyl-estradiol plus cyproterone acetate versus metformin effects on classic metabolic cardiovascular risk factors in women with the polycystic ovary syndrome.
    The Journal of clinical endocrinology and metabolism, 2007, Volume: 92, Issue:7

    Topics: Administration, Oral; Adult; Androgen Antagonists; Androgens; Blood Glucose; Cardiovascular Diseases; Cyproterone Acetate; Drug Combinations; Dyslipidemias; Ethinyl Estradiol; Female; Humans; Hypoglycemic Agents; Insulin Resistance; Lipids; Metformin; Polycystic Ovary Syndrome; Risk Factors

2007
Increased body iron stores of obese women with polycystic ovary syndrome are a consequence of insulin resistance and hyperinsulinism and are not a result of reduced menstrual losses.
    Diabetes care, 2007, Volume: 30, Issue:9

    Topics: Adolescent; Adult; Androgen Antagonists; Cyproterone Acetate; Drug Combinations; Ethinyl Estradiol; Female; Ferritins; Humans; Hyperinsulinism; Hypoglycemic Agents; Insulin Resistance; Iron; Metformin; Obesity; Oligomenorrhea; Polycystic Ovary Syndrome

2007
Serum uric acid concentration as non-classic cardiovascular risk factor in women with polycystic ovary syndrome: effect of treatment with ethinyl-estradiol plus cyproterone acetate versus metformin.
    Human reproduction (Oxford, England), 2008, Volume: 23, Issue:7

    Topics: Adolescent; Adult; Body Mass Index; Cross-Sectional Studies; Cyproterone Acetate; Drug Combinations; Ethinyl Estradiol; Female; Humans; Metformin; Obesity; Polycystic Ovary Syndrome; Risk Factors; Uric Acid

2008
Effects of an antiandrogenic oral contraceptive pill compared with metformin on blood coagulation tests and endothelial function in women with the polycystic ovary syndrome: influence of obesity and smoking.
    European journal of endocrinology, 2009, Volume: 160, Issue:3

    Topics: Adult; Androgen Antagonists; Blood Coagulation; Blood Platelets; Case-Control Studies; Contraceptives, Oral, Hormonal; Cyproterone Acetate; Drug Combinations; Endothelium, Vascular; Ethinyl Estradiol; Female; Fibrinogen; Homocysteine; Humans; Hypoglycemic Agents; Metformin; Obesity; Partial Thromboplastin Time; Polycystic Ovary Syndrome; Prothrombin; Smoking; Young Adult

2009
Efficacy of Chinese patent medicine Tian Gui Capsule in patients with polycystic ovary syndrome: a randomized controlled trial.
    Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine, 2011, Volume: 9, Issue:9

    Topics: Adolescent; Adult; Androgen Antagonists; Cyproterone Acetate; Drug Combinations; Drugs, Chinese Herbal; Ethinyl Estradiol; Female; Humans; Metformin; Phytotherapy; Polycystic Ovary Syndrome; Young Adult

2011
Ethinyl estradiol-cyproterone acetate versus low-dose pioglitazone-flutamide-metformin for adolescent girls with androgen excess: divergent effects on CD163, TWEAK receptor, ANGPTL4, and LEPTIN expression in subcutaneous adipose tissue.
    The Journal of clinical endocrinology and metabolism, 2012, Volume: 97, Issue:10

    Topics: Abdominal Fat; Adolescent; Androgen Antagonists; Angiopoietin-Like Protein 4; Angiopoietins; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Body Composition; Cyproterone Acetate; Dose-Response Relationship, Drug; Drug Combinations; Ethinyl Estradiol; Female; Flutamide; Gene Expression; Humans; Hyperandrogenism; Hypoglycemic Agents; Leptin; Metformin; Pioglitazone; Receptors, Cell Surface; Receptors, Tumor Necrosis Factor; Subcutaneous Fat; Thiazolidinediones; TWEAK Receptor

2012
Effects of ethinylestradiol-cyproterone acetate vs. pioglitazone-flutamide-metformin on plasma FGF21 levels in adolescent girls with androgen excess.
    Diabetes & metabolism, 2016, Volume: 42, Issue:3

    Topics: Adolescent; Cyproterone Acetate; Drug Combinations; Ethinyl Estradiol; Female; Fibroblast Growth Factors; Flutamide; Hirsutism; Humans; Hyperandrogenism; Hyperinsulinism; Longitudinal Studies; Metformin; Pioglitazone; Thiazolidinediones

2016
Effect of Diane-35, alone or in combination with orlistat or metformin in Chinese polycystic ovary syndrome patients.
    Archives of gynecology and obstetrics, 2018, Volume: 297, Issue:6

    Topics: Adipose Tissue; Adult; Androgen Antagonists; Androgens; Cyproterone Acetate; Drug Combinations; Ethinyl Estradiol; Female; Humans; Insulin Resistance; Metformin; Obesity; Orlistat; Overweight; Polycystic Ovary Syndrome; Treatment Outcome

2018
Doppler analysis of ovarian stromal blood flow changes after treatment with metformin versus ethinyl estradiol-cyproterone acetate in women with polycystic ovarian syndrome: A randomized controlled trial.
    Journal of gynecology obstetrics and human reproduction, 2019, Volume: 48, Issue:5

    Topics: Adult; Androgen Antagonists; Androgens; Body Mass Index; Contraceptives, Oral, Combined; Cyproterone Acetate; Drug Combinations; Ethinyl Estradiol; Female; Humans; Insulin; Insulin Resistance; Luteinizing Hormone; Metformin; Ovary; Polycystic Ovary Syndrome; Prospective Studies; Regional Blood Flow; Testosterone; Ultrasonography, Doppler, Color; Waist Circumference

2019
Therapeutic effects of puerarin on polycystic ovary syndrome: A randomized trial in Chinese women.
    Medicine, 2021, May-28, Volume: 100, Issue:21

    Topics: Administration, Oral; Adolescent; Adult; China; Cholesterol; Cyproterone Acetate; Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; Ethinyl Estradiol; Female; Humans; Isoflavones; Metformin; Obesity; Polycystic Ovary Syndrome; Primary Ovarian Insufficiency; Sex Hormone-Binding Globulin; Superoxide Dismutase; Tablets; Testosterone; Treatment Outcome; Young Adult

2021

Other Studies

13 other study(ies) available for metformin and cyproterone acetate, ethinyl estradiol drug combination

ArticleYear
[Effect of 6-month treatment with oral antiandrogen alone and in combination with insulin sensitizers on body composition, hormonal and metabolic parameters in women with polycystic ovary syndrome (PCOS) in order to determine therapeutic strategy].
    Akusherstvo i ginekologiia, 2006, Volume: 45, Issue:7

    Topics: Androgen Antagonists; Blood Glucose; Body Composition; Cyproterone Acetate; Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; Ethinyl Estradiol; Female; Humans; Hypoglycemic Agents; Insulin; Lipids; Metformin; Polycystic Ovary Syndrome; Rosiglitazone; Thiazolidinediones; Time Factors; Treatment Outcome

2006
Homeostasis model assessment-insulin resistance (HOMA-IR), a key role for assessing the ovulation function in polycystic ovary syndrome (PCOS) patients with insulin resistance.
    Endocrine journal, 2008, Volume: 55, Issue:5

    Topics: Cyproterone Acetate; Drug Combinations; Ethinyl Estradiol; Female; Homeostasis; Humans; Hypoglycemic Agents; Insulin Resistance; Metformin; Models, Biological; Ovarian Follicle; Ovary; Ovulation; Polycystic Ovary Syndrome; Sensitivity and Specificity

2008
The platelet activating factor acetyl hydrolase, oxidized low-density lipoprotein, paraoxonase 1 and arylesterase levels in treated and untreated patients with polycystic ovary syndrome.
    Archives of gynecology and obstetrics, 2014, Volume: 290, Issue:5

    Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Adult; Androgen Antagonists; Aryldialkylphosphatase; Body Mass Index; Carboxylic Ester Hydrolases; Case-Control Studies; Cyproterone Acetate; Drug Combinations; Ethinyl Estradiol; Female; Humans; Hypoglycemic Agents; Lipoproteins, LDL; Metformin; Phospholipase A2 Inhibitors; Platelet Activating Factor; Polycystic Ovary Syndrome; Polymorphism, Single Nucleotide; Treatment Outcome

2014
How medical treatment affects mean platelet volume as a cardiovascular risk marker in polycystic ovary syndrome?
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2015, Volume: 26, Issue:8

    Topics: Adolescent; Adult; Androgen Antagonists; Biomarkers; Blood Platelets; Body Mass Index; C-Reactive Protein; Cardiovascular Diseases; Case-Control Studies; Cyproterone Acetate; Drug Combinations; Ethinyl Estradiol; Female; Humans; Hypoglycemic Agents; Insulin Resistance; Leukocyte Count; Mean Platelet Volume; Metformin; Polycystic Ovary Syndrome; Regression Analysis; Treatment Outcome

2015
Polycystic ovary syndrome (PCOS): metformin.
    BMJ clinical evidence, 2015, Mar-27, Volume: 2015

    Topics: Androgen Antagonists; Cyproterone Acetate; Drug Combinations; Ethinyl Estradiol; Female; Humans; Hypoglycemic Agents; Metformin; Polycystic Ovary Syndrome; Weight Reduction Programs

2015
Metabolic profile of Diane-35 versus Diane-35 plus metformin in Chinese PCOS women under standardized life-style changes.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2015, Volume: 31, Issue:7

    Topics: Adolescent; Adult; Androgen Antagonists; China; Cyproterone Acetate; Drug Combinations; Drug Therapy, Combination; Ethinyl Estradiol; Female; Humans; Hyperandrogenism; Hypoglycemic Agents; Metabolome; Metformin; Polycystic Ovary Syndrome; Treatment Outcome; Young Adult

2015
Exploring the significance of sex hormone-binding globulin examination in the treament of women with polycystic ovarian syndrome (PCOS).
    Clinical and experimental obstetrics & gynecology, 2015, Volume: 42, Issue:3

    Topics: Abortion, Spontaneous; Adult; Androgen Antagonists; Blood Glucose; Body Mass Index; Clomiphene; Cyproterone Acetate; Drug Combinations; Drug Therapy, Combination; Estradiol; Ethinyl Estradiol; Female; Fertility Agents, Female; Follicle Stimulating Hormone; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Live Birth; Luteinizing Hormone; Metformin; Obesity; Ovulation Induction; Polycystic Ovary Syndrome; Prolactin; Sex Hormone-Binding Globulin; Testosterone; Treatment Outcome; Young Adult

2015
Management of polycystic ovarian syndrome with Diane-35 or Diane-35 plus metformin.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2016, Volume: 32, Issue:2

    Topics: Adult; Androgen Antagonists; Cyproterone Acetate; Drug Combinations; Ethinyl Estradiol; Female; Humans; Hypoglycemic Agents; Metformin; Outcome Assessment, Health Care; Polycystic Ovary Syndrome; Young Adult

2016
Restored Plasma Anandamide and Endometrial Expression of Fatty Acid Amide Hydrolase in Women With Polycystic Ovary Syndrome by the Combination Use of Diane-35 and Metformin.
    Clinical therapeutics, 2017, Volume: 39, Issue:4

    Topics: Adult; Amidohydrolases; Androgen Antagonists; Arachidonic Acids; Cyproterone Acetate; Drug Combinations; Endocannabinoids; Endometrium; Ethinyl Estradiol; Female; Glycerides; Humans; Infertility, Female; Metformin; Polycystic Ovary Syndrome; Polyunsaturated Alkamides; Receptors, Cannabinoid; Young Adult

2017
Effect of orlistat or metformin in overweight and obese polycystic ovary syndrome patients with insulin resistance.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2018, Volume: 34, Issue:5

    Topics: Adult; Anti-Obesity Agents; Cyproterone Acetate; Drug Combinations; Drug Therapy, Combination; Ethinyl Estradiol; Female; Humans; Hypoglycemic Agents; Insulin Resistance; Lactones; Metformin; Obesity; Orlistat; Overweight; Polycystic Ovary Syndrome; Young Adult

2018
Association between CD16
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2019, Volume: 145, Issue:1

    Topics: Adult; Biomarkers; Case-Control Studies; China; Cross-Sectional Studies; Cyproterone Acetate; Drug Combinations; Drug Therapy, Combination; Ethinyl Estradiol; Female; Humans; Hyperandrogenism; Insulin Resistance; Metformin; Monocytes; Polycystic Ovary Syndrome; Prospective Studies; Receptors, IgG

2019
Combined use of Diane-35 and metformin improves the ovulation in the PCOS rat model possibly via regulating glycolysis pathway.
    Reproductive biology and endocrinology : RB&E, 2020, Jun-03, Volume: 18, Issue:1

    Topics: Androgen Antagonists; Animals; Apoptosis; Body Weight; Cyproterone Acetate; Disease Models, Animal; Drug Combinations; Drug Therapy, Combination; Ethinyl Estradiol; Female; Glycolysis; Hypoglycemic Agents; Insulin Resistance; Lactate Dehydrogenase 5; Luteinizing Hormone; Metformin; Ovary; Ovulation; Polycystic Ovary Syndrome; Pyruvate Kinase; Rats; Sirtuin 1; Testosterone

2020
Diane-35 and Metformin Induce Autophagy and Apoptosis in Polycystic Ovary Syndrome Women with Early-Stage Endometrial Carcinoma.
    Genes, 2022, 01-12, Volume: 13, Issue:1

    Topics: Androgen Antagonists; Animals; Apoptosis; Autophagy; Cyproterone Acetate; Drug Combinations; Drug Therapy, Combination; Endometrial Neoplasms; Ethinyl Estradiol; Female; Glucose Transporter Type 4; Hypoglycemic Agents; Insulin-Like Growth Factor I; Metformin; Mice; Polycystic Ovary Syndrome; Receptors, Androgen

2022