metformin has been researched along with curcumin in 24 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 13 (54.17) | 24.3611 |
| 2020's | 11 (45.83) | 2.80 |
| Authors | Studies |
|---|---|
| Darvesh, AS; Geldenhuys, WJ; Leeper, TC; Morris, DL; Sullivan, PG; Yonutas, HM | 1 |
| Arora, S; Chaturvedi, A; Heuser, M; Joshi, G; Kumar, R; Patil, S | 1 |
| Steinman, TI | 1 |
| Chen, J; Hann, SS; Wang, Z; Wu, J; Zhao, S; Zheng, F | 1 |
| Ben, Q; Du, Y; Gao, J; Gong, Y; He, X; Huang, L; Jin, J; Li, Z; Man, X; Ning, X; Wu, H; Xu, M | 1 |
| Babica, P; Čtveráčková, L; Lenčešová, Z; Trosko, JE; Upham, BL | 1 |
| Antony, B; Benny, M; Hicks, W; Jacob, T; Kulsum, S; Kumar, VV; Kuriakose, MA; Kuruvilla, BT; Lakshminarayan, P; Raghavan, N; Raju, N; Ravindra, DR; Seshadri, M; Sharma, A; Siddappa, G; Sudheendra, HV; Sunny, SP; Suresh, A | 1 |
| Dadashpour, M; Farajzadeh, R; Javidfar, S; Lotfi-Attari, J; Pilehvar-Soltanahmadi, Y; Sadeghzadeh, H; Shafiei-Irannejad, V; Zarghami, N | 1 |
| Cao, ZQ; Cheng, YN; Gong, FL; Guo, XL; Yu, LG; Zhang, HH; Zhang, Y | 1 |
| Chudhuri, A; Dehghan, E; Dehghani, M; Goodarzi, M; Hakimi, A; Lin, R; Mirzaei, H; Robertson, S; Saremi, B; Tu, X; Yadavali, S; Zhang, Y | 1 |
| Abdel Baky, NA; Abdelsamia, EM; Balah, A; Khaleel, SA | 1 |
| Biron, VL; Conrad, D; Harris, J; Kostiuk, M; Lindsay, C; O'Connell, DA; Seikaly, H | 1 |
| Cao, L; Han, J; Kumar Sah, S; Xie, Y; Zhi, D | 1 |
| Bahador, A; Chiniforush, N; Plotino, G; Pourhajibagher, M | 1 |
| Cao, H; Lu, J; Tang, H; Xu, P; Yan, X; Zheng, Y; Zhou, L | 1 |
| Eslami, SS; Jafari, D; Montazeri, H; Sadeghizadeh, M; Tarighi, P | 1 |
| Cordero-Martínez, E; León-Ramírez, C; Ruiz-Herrera, J; Sánchez-Segura, L; Soberanes-Gutiérrez, CV; Vega-Arreguín, JC | 1 |
| Atkin, SL; Azarpazhooh, MR; Heydari, B; Karimi-Zarchi, M; Sahebkar, A; Simental-Mendía, LE; Sohrevardi, SM; Teymourzadeh, M | 1 |
| Chai, HC; Chua, KH; Lim, SK; Mahendran, R; Ong, KC | 1 |
| Abdulmalek, S; Awad, D; Balbaa, M; Eldala, A | 1 |
| Dasuni Wasana, PW; Muangnoi, C; Rojsitthisak, P; Towiwat, P; Vajragupta, O | 1 |
| Chen, M; Duan, P; Gao, H; Gong, Y; Li, J; Lu, A; Xie, J; Xu, H | 1 |
| Dasuni Wasana, PW; Rojsitthisak, P; Towiwat, P; Vajragupta, O | 1 |
| Apte, K; Kumbhare, K; Mishra, S; Patil, D; Patwardhan, B; Shengule, S | 1 |
3 review(s) available for metformin and curcumin
| Article | Year |
|---|---|
Polycystic kidney disease: a 2011 update.
Topics: Antineoplastic Agents; Benzazepines; Curcumin; Everolimus; Gastrointestinal Agents; Glomerular Filtration Rate; Humans; Hypertension; Hypoglycemic Agents; Immunosuppressive Agents; Indazoles; Kidney; Metformin; Octreotide; Organ Size; Polycystic Kidney, Autosomal Dominant; Sirolimus; Sodium; Tolvaptan | 2012 |
Natural-derived compounds and their mechanisms in potential autosomal dominant polycystic kidney disease (ADPKD) treatment.
Topics: Antioxidants; Chalcones; Curcumin; Diterpenes; Diterpenes, Kaurane; Emodin; Epoxy Compounds; Estrogen Antagonists; Flavanones; Humans; Hypoglycemic Agents; Metformin; Phenanthrenes; Plant Extracts; Polycystic Kidney, Autosomal Dominant; Protein Kinase Inhibitors; Quercetin; Resveratrol | 2021 |
Recent progress and research trend of anti-cataract pharmacology therapy: A bibliometric analysis and literature review.
Topics: Bibliometrics; Cataract; Curcumin; Humans; Lanosterol; Metformin; Oxysterols; Resveratrol | 2022 |
1 trial(s) available for metformin and curcumin
| Article | Year |
|---|---|
Therapeutic Effect of Curcumin in Women with Polycystic Ovary Syndrome Receiving Metformin: A Randomized Controlled Trial.
Topics: Blood Glucose; Curcumin; Female; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Metformin; Polycystic Ovary Syndrome | 2021 |
20 other study(ies) available for metformin and curcumin
| Article | Year |
|---|---|
Identification of small molecules that bind to the mitochondrial protein mitoNEET.
Topics: Hypoglycemic Agents; Ligands; Mitochondrial Proteins; Protein Binding; Small Molecule Libraries; Thiazolidinediones | 2016 |
A Perspective on Medicinal Chemistry Approaches for Targeting Pyruvate Kinase M2.
Topics: Allosteric Regulation; Allosteric Site; Carrier Proteins; Chemistry, Pharmaceutical; Glycolysis; Humans; Membrane Proteins; Protein Kinase Inhibitors; Thyroid Hormone-Binding Proteins; Thyroid Hormones | 2022 |
Targeting EP4 by curcumin through cross talks of AMP-dependent kinase alpha and p38 mitogen-activated protein kinase signaling: the role of PGC-1α and Sp1.
Topics: Adenylate Kinase; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Curcumin; Down-Regulation; Enzyme Activation; Gene Expression Regulation, Neoplastic; Head and Neck Neoplasms; Humans; Metformin; Molecular Targeted Therapy; p38 Mitogen-Activated Protein Kinases; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Receptors, Prostaglandin E, EP4 Subtype; RNA Interference; Signal Transduction; Transcription Factors | 2013 |
Bulk pancreatic cancer cells can convert into cancer stem cells(CSCs) in vitro and 2 compounds can target these CSCs.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily G, Member 2; beta Catenin; Cell Line, Tumor; Cell Proliferation; Cell Survival; Curcumin; Humans; Ki-67 Antigen; Metformin; Mice; Mice, Inbred NOD; Mice, SCID; Neoplastic Stem Cells; Octamer Transcription Factor-3; Pancreatic Neoplasms; Proto-Oncogene Proteins c-bcr; Receptor, Notch1; Xenograft Model Antitumor Assays; Zinc Finger Protein GLI1 | 2016 |
Chemopreventive Agents Attenuate Rapid Inhibition of Gap Junctional Intercellular Communication Induced by Environmental Toxicants.
Topics: Animals; Anticarcinogenic Agents; Caprylates; Carcinogens; Cell Communication; Cell Survival; Cells, Cultured; Curcumin; DDT; Epithelial Cells; Fluorenes; Fluorocarbons; Gap Junctions; Hexachlorocyclohexane; Liver; Metformin; Rats; Rats, Inbred F344; Tetradecanoylphorbol Acetate | 2016 |
Curcumin and metformin-mediated chemoprevention of oral cancer is associated with inhibition of cancer stem cells.
Topics: 4-Nitroquinoline-1-oxide; AC133 Antigen; Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Movement; Cell Proliferation; Chemoprevention; Curcumin; Female; Hyaluronan Receptors; Hypoglycemic Agents; Metformin; Mice, Inbred C57BL; Mouth; Mouth Neoplasms; Neoplastic Stem Cells | 2017 |
Nano-encapsulated metformin-curcumin in PLGA/PEG inhibits synergistically growth and hTERT gene expression in human breast cancer cells.
Topics: Breast Neoplasms; Capsules; Cell Line, Tumor; Cell Proliferation; Curcumin; Drug Carriers; Drug Liberation; Drug Synergism; Gene Expression Regulation, Neoplastic; Humans; Metformin; Nanoparticles; Particle Size; Polyesters; Polyethylene Glycols; Telomerase | 2018 |
Metformin incombination with curcumin inhibits the growth, metastasis, and angiogenesis of hepatocellular carcinoma in vitro and in vivo.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Cell Line; Cell Proliferation; Cells, Cultured; Curcumin; Female; Hep G2 Cells; Humans; Liver Neoplasms; Metformin; Mice, Inbred BALB C; Mice, Nude; Neoplasm Metastasis; Neovascularization, Pathologic; Signal Transduction; Tumor Burden; Xenograft Model Antitumor Assays | 2018 |
Hydralazine induces stress resistance and extends C. elegans lifespan by activating the NRF2/SKN-1 signalling pathway.
Topics: Animals; Antihypertensive Agents; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Cell Line, Tumor; Curcumin; Disease Models, Animal; DNA-Binding Proteins; Enzyme Inhibitors; Humans; Hydralazine; Hypoglycemic Agents; In Vitro Techniques; Longevity; Metformin; Neurons; Neuroprotective Agents; NF-E2-Related Factor 2; Stress, Physiological; Tauopathies; Transcription Factors | 2017 |
Curcumin augments the cardioprotective effect of metformin in an experimental model of type I diabetes mellitus; Impact of Nrf2/HO-1 and JAK/STAT pathways.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cardiotonic Agents; Curcumin; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Drug Synergism; Heart; Heme Oxygenase-1; Janus Kinases; Male; Membrane Proteins; Metformin; Myocardium; NF-E2-Related Factor 2; Rats; Rats, Wistar; STAT Transcription Factors; Treatment Outcome | 2019 |
Antitumour effects of metformin and curcumin in human papillomavirus positive and negative head and neck cancer cells.
Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; Curcumin; Gene Expression Regulation, Neoplastic; Humans; Ki-67 Antigen; Metformin; Papillomaviridae; Papillomavirus Infections; Squamous Cell Carcinoma of Head and Neck | 2019 |
Combinational effect of curcumin and metformin against gentamicin-induced nephrotoxicity: Involvement of antioxidative, anti-inflammatory and antiapoptotic pathway.
Topics: Acute Kidney Injury; Animals; Anti-Inflammatory Agents; Apoptosis; Curcumin; Drug Combinations; Gentamicins; Kidney; Metformin; Oxidative Stress; Rats; Rats, Wistar | 2019 |
Dual wavelength irradiation antimicrobial photodynamic therapy using indocyanine green and metformin doped with nano-curcumin as an efficient adjunctive endodontic treatment modality.
Topics: Anti-Bacterial Agents; Bacterial Load; Bicuspid; Biofilms; Curcumin; Disinfection; Enterococcus faecalis; In Vitro Techniques; Indocyanine Green; Lasers, Semiconductor; Metformin; Photochemotherapy; Photosensitizing Agents; Tooth Root | 2020 |
Blockade of high mobility group box 1 involved in the protective of curcumin on myocardial injury in diabetes in vivo and in vitro.
Topics: Animals; Cardiotonic Agents; Caspase 1; Cell Line; Cell Survival; Curcumin; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Electrocardiography; Gene Expression Regulation; Glucose; Glucose Tolerance Test; HMGB1 Protein; Hypoglycemic Agents; Interleukin-1beta; Male; Metformin; Mice; Mice, Inbred C57BL; Myocardium; Myocytes, Cardiac; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Signal Transduction | 2020 |
Combination of Curcumin and Metformin Inhibits Cell Growth and Induces Apoptosis without Affecting the Cell Cycle in LNCaP Prostate Cancer Cell Line.
Topics: Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Curcumin; Humans; Male; Metformin; Prostatic Neoplasms | 2021 |
Cell death in Ustilago maydis: comparison with other fungi and the effect of metformin and curcumin on its chronological lifespan.
Topics: Basidiomycota; Cell Death; Culture Media; Curcumin; Metformin; Microbial Viability; Reactive Oxygen Species; Saccharomyces cerevisiae; Yarrowia | 2020 |
Ameliorative effect of curcumin and zinc oxide nanoparticles on multiple mechanisms in obese rats with induced type 2 diabetes.
Topics: Animals; Antioxidants; Blood Glucose; Curcumin; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet, High-Fat; Hypoglycemic Agents; Inflammation; Insulin; Insulin Resistance; Liver; Male; Metformin; Nanoparticles; Obesity; Oxidative Stress; Rats; Streptozocin; Zinc Oxide | 2021 |
Curcumin and metformin synergistically modulate peripheral and central immune mechanisms of pain.
Topics: Analgesics; Anti-Inflammatory Agents; Curcumin; Humans; Metformin; Pain | 2022 |
Metformin and curcumin co-encapsulated chitosan/alginate nanoparticles as effective oral carriers against pain-like behaviors in mice.
Topics: Alginates; Animals; Caco-2 Cells; Chitosan; Curcumin; Drug Carriers; Humans; Metformin; Mice; Nanoparticles; Particle Size | 2023 |
Herb-drug interaction of Nisha Amalaki and Curcuminoids with metformin in normal and diabetic condition: A disease system approach.
Topics: Animals; Curcuma; Diabetes Mellitus, Experimental; Drug Therapy, Combination; Herb-Drug Interactions; Hypoglycemic Agents; Male; Metformin; Phyllanthus emblica; Plant Extracts; Rats; Rats, Wistar | 2018 |