Compounds > metformin

metformin and crizotinib

metformin has been researched along with crizotinib in 3 studies

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (66.67)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ1
Han, R; He, Y; Li, L; Lin, C; Lu, C; Peng, T; Wang, Y; Zhang, K1
Ashton, JC; Bland, AR; Bower, RL; Rosengren, RJ; Shrestha, N1

Other Studies

3 other study(ies) available for metformin and crizotinib

ArticleYear
Identification of potent Yes1 kinase inhibitors using a library screening approach.
    Bioorganic & medicinal chemistry letters, 2013, Aug-01, Volume: 23, Issue:15

    Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship

2013
Metformin restores crizotinib sensitivity in crizotinib-resistant human lung cancer cells through inhibition of IGF1-R signaling pathway.
    Oncotarget, 2016, Jun-07, Volume: 7, Issue:23

    Topics: Anaplastic Lymphoma Kinase; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Crizotinib; Drug Resistance, Neoplasm; Humans; Lung Neoplasms; Metformin; Neoplasm Invasiveness; Pyrazoles; Pyridines; Receptor Protein-Tyrosine Kinases; Receptor, IGF Type 1; Receptors, Somatomedin; Signal Transduction

2016
The effect of metformin in EML
    Biochemical pharmacology, 2021, Volume: 183

    Topics: A549 Cells; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cell Survival; Crizotinib; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Lung Neoplasms; Male; Metformin; Mice; Mice, Inbred BALB C; Mice, Nude; Oncogene Proteins, Fusion; Rodentia

2021