metformin and caffeine

metformin has been researched along with caffeine in 29 studies

Research

Studies (29)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (3.45)	18.7374
1990's	1 (3.45)	18.2507
2000's	8 (27.59)	29.6817
2010's	14 (48.28)	24.3611
2020's	5 (17.24)	2.80

Authors

Authors	Studies
Lombardo, F; Obach, RS; Waters, NJ	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Campillo, NE; Guerra, A; Páez, JA	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Glen, RC; Lowe, R; Mitchell, JB	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Bray, GA	1
UESUGI, Y	1
Lehrman, MA; Shang, J	1
Homan, G; Moran, L; Noakes, M; Norman, RJ	1
Amran, MS; Azam, AT; Hossain, MA; Mohiuddin, M	1
Jakova, E; Lee, JS	1
Čapo, I; Lalošević, D; Miljković, D; Popović, DJ; Popović, JK; Popović, KJ	1
Liu, SY; Shao, XT; Song, XB; Tan, DQ; Wang, DG; Wang, Z	1
Cong, ZX; Liu, SY; Shao, XT; Wang, DG; Wang, Z; Zheng, XY	1
Dhakal, S; Lee, Y; Sang, J	1
Borutaite, V; Jankeviciute, S; Svirskiene, N; Svirskis, G	1
Belfort, B; Di Chiara Roupert, R; Imfeld, G; Prieto-Espinoza, M; Weill, S	1

Reviews

3 review(s) available for metformin and caffeine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Drug treatment of obesity. Bailliere's best practice & research. Clinical endocrinology & metabolism, 1999, Volume: 13, Issue:1 Topics: Androgen Antagonists; Androgens; Anti-Obesity Agents; Appetite Depressants; Caffeine; Central Nervous System Stimulants; Energy Metabolism; Enzyme Inhibitors; Ephedrine; Humans; Hypoglycemic Agents; Lactones; Lipase; Metformin; Obesity; Orlistat; Patient Selection	1999
Lifestyle choices, diet, and insulin sensitizers in polycystic ovary syndrome. Endocrine, 2006, Volume: 30, Issue:1 Topics: Age Factors; Alcohol Drinking; Body Weight; Caffeine; Female; Humans; Hypoglycemic Agents; Infertility, Female; Life Style; Metformin; Nutritional Status; Polycystic Ovary Syndrome; Smoking; Stress, Physiological	2006

Other Studies

26 other study(ies) available for metformin and caffeine

Article	Year
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data. European journal of medicinal chemistry, 2009, Volume: 44, Issue:11 Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Neural computational prediction of oral drug absorption based on CODES 2D descriptors. European journal of medicinal chemistry, 2010, Volume: 45, Issue:3 Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
Predicting phospholipidosis using machine learning. Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5 Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Prediction of drug intestinal absorption by new linear and non-linear QSPR. European journal of medicinal chemistry, 2011, Volume: 46, Issue:1 Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics	2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
[EFFECTS OF VARIOUS NATURAL ORGANIC SUBSTANCES AND AMINO ACIDS ON THE BLOOD SURGAR LEVEL AND EXPERIMENTAL STUDIES ON ORAL HYPOGLYCEMIC AGENTS]. Nihon Naibunpi Gakkai zasshi, 1963, Nov-20, Volume: 39 Topics: Amino Acids; Animals; Bile Acids and Salts; Blood Chemical Analysis; Blood Glucose; Caffeine; Chlorpropamide; Creatine; Creatinine; Cystine; Diabetes Mellitus, Experimental; Hippurates; Hypoglycemic Agents; Injections; Injections, Intravenous; Metformin; Pathology; Pharmacology; Rats; Research; Salts; Theobromine; Theophylline; Tyrosine	1963
Activation of glycogen phosphorylase with 5-aminoimidazole-4-carboxamide riboside (AICAR). Assessment of glycogen as a precursor of mannosyl residues in glycoconjugates. The Journal of biological chemistry, 2004, Mar-26, Volume: 279, Issue:13 Topics: Amides; Aminoimidazole Carboxamide; Binding Sites; Caffeine; Catalysis; Cells, Cultured; Chromatography, High Pressure Liquid; Cyclic AMP; Cyclic GMP; Enzyme Activation; Fibroblasts; Glycogen; Glycogen Phosphorylase; Humans; Hypoglycemic Agents; Indoles; Lipid Metabolism; Mannose; Metformin; Oligosaccharides; Phosphorylation; Protein Binding; Ribonucleotides; Skin; Time Factors	2004
In vive effects of gliclazide and metformin on the plasma concentration of caffeine in healthy rats. Pakistan journal of biological sciences : PJBS, 2009, May-01, Volume: 12, Issue:9 Topics: Animals; Caffeine; Gliclazide; Hypoglycemic Agents; Metformin; Rats	2009
Behavior of α-synuclein-drug complexes during nanopore analysis with a superimposed AC field. Electrophoresis, 2017, Volume: 38, Issue:2 Topics: alpha-Synuclein; Caffeine; Electricity; Electrophoresis; Humans; Metformin; Models, Chemical; Nanopores; Nicotine; Parkinson Disease; Pharmaceutical Preparations	2017
Caffeine induces metformin anticancer effect on fibrosarcoma in hamsters. European review for medical and pharmacological sciences, 2018, Volume: 22, Issue:8 Topics: Animals; Antineoplastic Agents; Caffeine; Cricetinae; Drug Synergism; Female; Fibrosarcoma; Male; Mesocricetus; Metformin; Random Allocation; Treatment Outcome	2018
Assessment of metformin, nicotine, caffeine, and methamphetamine use during Chinese public holidays. Chemosphere, 2020, Volume: 258 Topics: Caffeine; China; Cities; Holidays; Humans; Metformin; Methamphetamine; Nicotine; Substance-Related Disorders; Wastewater; Water Pollutants, Chemical	2020
Spatial analysis of metformin use compared with nicotine and caffeine consumption through wastewater-based epidemiology in China. Ecotoxicology and environmental safety, 2021, Jan-15, Volume: 208 Topics: Caffeine; China; Cities; Diabetes Mellitus, Type 2; Humans; Metformin; Nicotiana; Nicotine; Spatial Analysis; Tobacco Use; Wastewater; Wastewater-Based Epidemiological Monitoring	2021
Cucurbitacin B Suppresses Hyperglycemia Associated with a High Sugar Diet and Promotes Sleep in Molecules and cells, 2021, Feb-28, Volume: 44, Issue:2 Topics: Animals; Caffeine; Diet; Dietary Sugars; Drosophila melanogaster; Drosophila Proteins; Feeding Behavior; Glucose; Hemolymph; Hyperglycemia; Male; Memory; Metformin; Mutation; Organ Specificity; Receptors, Cell Surface; Sleep; Taste; Triglycerides; Triterpenes	2021
Effects of Metformin on Spontaneous Ca International journal of molecular sciences, 2021, Aug-31, Volume: 22, Issue:17 Topics: Animals; Caffeine; Calcium Signaling; Chromans; Cyclosporine; Electron Transport Complex I; Female; Hypoxia; Male; Metformin; Microglia; Mitochondria; Mitochondrial Membrane Transport Proteins; Neurons; Primary Cell Culture; Rats; Reactive Oxygen Species; Rotenone	2021
Reactive transport of micropollutants in laboratory aquifers undergoing transient exposure periods. The Science of the total environment, 2023, Jan-15, Volume: 856, Issue:Pt 2 Topics: Atrazine; Caffeine; Groundwater; Metformin; RNA, Ribosomal, 16S; Water; Water Pollutants, Chemical	2023