Compounds > metformin

metformin and bi 2536

metformin has been researched along with bi 2536 in 3 studies

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ1
Ahmad, N; Hodges, K; Kuang, S; Liu, X; Ratliff, T; Shao, C1
Ahmad, N; Chen, L; Liu, X1

Other Studies

3 other study(ies) available for metformin and bi 2536

ArticleYear
Identification of potent Yes1 kinase inhibitors using a library screening approach.
    Bioorganic & medicinal chemistry letters, 2013, Aug-01, Volume: 23, Issue:15

    Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship

2013
Inhibition of polo-like kinase 1 (Plk1) enhances the antineoplastic activity of metformin in prostate cancer.
    The Journal of biological chemistry, 2015, Jan-23, Volume: 290, Issue:4

    Topics: Animals; Antineoplastic Agents; Cell Cycle; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Cell Separation; Cell Survival; Disease Progression; Flow Cytometry; Glycolysis; Humans; Male; Metformin; Mice; Mitosis; Neoplasm Transplantation; Polo-Like Kinase 1; Prostate-Specific Antigen; Prostatic Neoplasms; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Pteridines; RNA Interference; Signal Transduction; Tumor Suppressor Protein p53

2015
Combining p53 stabilizers with metformin induces synergistic apoptosis through regulation of energy metabolism in castration-resistant prostate cancer.
    Cell cycle (Georgetown, Tex.), 2016, Volume: 15, Issue:6

    Topics: Acetanilides; Antineoplastic Agents; Apoptosis; Cell Cycle Proteins; Cell Line, Tumor; Drug Synergism; Drug Therapy, Combination; Gene Expression Regulation, Neoplastic; Glycolysis; Humans; Male; Metformin; Mitochondria; Mitosis; Oxidative Phosphorylation; Polo-Like Kinase 1; Prostate; Prostatic Neoplasms, Castration-Resistant; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Pteridines; Signal Transduction; Sirtuin 1; Thiourea; Tumor Suppressor Protein p53

2016