Compounds > metformin

metformin and azd 6244

metformin has been researched along with azd 6244 in 3 studies

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ1
Bianco, R; Castellone, MD; Ciaramella, V; Ciardiello, F; De Vita, F; Della Corte, CM; Di Mauro, C; Fasano, M; Martinelli, E; Morgillo, F; Orditura, M; Papaccio, F; Sasso, FC; Troiani, T1

Other Studies

3 other study(ies) available for metformin and azd 6244

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Identification of potent Yes1 kinase inhibitors using a library screening approach.
    Bioorganic & medicinal chemistry letters, 2013, Aug-01, Volume: 23, Issue:15

    Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship

2013
Metformin increases antitumor activity of MEK inhibitors through GLI1 downregulation in LKB1 positive human NSCLC cancer cells.
    Oncotarget, 2016, Jan-26, Volume: 7, Issue:4

    Topics: AMP-Activated Protein Kinase Kinases; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Benzimidazoles; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Cell Proliferation; Chromatin Immunoprecipitation; Drug Synergism; Female; Gene Expression Regulation, Neoplastic; Humans; Hypoglycemic Agents; Immunoenzyme Techniques; Lung Neoplasms; MAP Kinase Kinase 1; Metformin; Mice; Mice, Inbred BALB C; Mice, Nude; Niacinamide; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Transcription Factors; Tumor Cells, Cultured; Xenograft Model Antitumor Assays; Zinc Finger Protein GLI1

2016